Proteoglycans and pattern formation: Sugar biochemistry meets developmental genetics

Trends in Genetics

Volumn 16, Issue 5, 2000, Pages 206-212

  Selleck, Scott B ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSAMINOGLYCAN; GLYCOSYLTRANSFERASE; GLYPICAN; GROWTH FACTOR; HEPARAN; PROTEOGLYCAN; SULFOTRANSFERASE; SYNDECAN; URIDINE DIPHOSPHATE GLUCOSE DEHYDROGENASE;

BODY SIZE; CARBOHYDRATE METABOLISM; CARBOHYDRATE SYNTHESIS; CELL SURFACE; DEVELOPMENT; DROSOPHILA; ENZYME ACTIVITY; GENE EXPRESSION; HEREDITARY MULTIPLE EXOSTOSIS; HUMAN; MORPHOGENESIS; MOUSE; NEPHROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; BODY PATTERNING; DROSOPHILA PROTEINS; GLYCOSAMINOGLYCANS; GROWTH SUBSTANCES; HEPARITIN SULFATE; HUMANS; INSECT PROTEINS; MEMBRANE GLYCOPROTEINS; MICE; PROTEOGLYCANS; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; WILMS TUMOR;

EID: 0034191875     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9525(00)01997-1     Document Type: Review

References (44)

1. Pilia, G. et al. (1996) Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nat. Genet. 12, 241-247
2. McCormick, C. et al. (1998) The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate. Nat. Genet. 19, 158-161
3. Lind, T. et al. (1998) The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate. J. Biol. Chem. 273, 26265-26268
4. Lindahl, U. et al. (1998) Regulated diversity of heparan sulfate. J. Biol. Chem. 273, 24979-24982
5. Maccarana, M. et al. (1996) Domain structure of heparan sulfates from bovine organs. J. Biol. Chem. 271, 17804-17810
6. Feyzi, E. et al. (1998) Age-dependent modulation of heparan sulfate structure and function. J. Biol. Chem. 273, 13395-13398
7. Bernfield, M. et al. (1999) Functions of cell surface heparan sulfate proteoglycans. Annu. Rev. Biochem. 68, 729-777
8. Nakato, H. et al. (1995) The division abnormally delayed (dally) gene: A putative integral membrane proteoglycan required for cell division patterning during postembryonic development of the nervous system in Drosophila. Development 121, 3687-3702
9. Tsuda, M. et al. (1999) A cell surface proteoglycan, dally, regulates wingless signalling in Drosophila. Nature 400, 276-280
10. Neri, G. et al. (1998) Clinical and molecular aspects of the Simpson-Golabi-Behmel syndrome. Am. J. Med. Genet. 79, 279-2839
11. Cano-Gauci, D.F. et al. (1999) Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndrome. J. Cell Biol. 146, 255-264
12. Olwin, B.B. and Rapraeger, A. (1992) Repression of myogenic differentiation by aFGF, bFGF, and K-FGF is dependent on cellular heparan sulfate. J. Cell Biol. 118, 631-639
13. Rapraeger, A.C. et al. (1991) Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation. Science 252, 1705-1708
14. Plotnikov, A.N. et al. (1999) Structural basis for FGF receptor dimerization and activation. Cell 98, 641-650
15. Reichsman, F. et al. (1996) Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction. J. Cell Biol. 135, 819-827
16. Aviezer, D. and Yayon, A. (1994) Heparin-dependent binding and autophosphorylation of epidermal growth factor (EGF) receptor by heparin-binding EGF-like growth factor but not EGF. Proc. Natl. Acad. Sci. U. S. A. 91, 12173-12177
17. Zioncheck, T.F. et al. (1995) Sulfated oligosaccharides promote hepatocyte growth factor association and govern its mitogenic activity. J. Biol. Chem. 270, 16871-16878
18. Jackson, S.M. et al. (1997) Dally, a Drosophila glypican, controls cellular responses to the TGF-β-related morphogen, Dpp. Development 124, 4113-4120
19. Lin, X. and Perrimon, N. (1999) Dally cooperates with Drosophila frizzled 2 to transduce wingless signalling. Nature 400, 281-284
20. Bhanot, P. et al. (1996) A new member of the frizzled family from Drosophila functions as a wingless receptor. Nature 382, 225-230
21. Häcker, U. et al. (1997) The Drosophila sugarless gene modulates wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. Development 124, 3565-3573
22. Binari, R.C. et al. (1997) Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling. Development 124, 2623-2632
23. Haerry, T.E. et al. (1997) Defects in glucuronate biosynthesis disrupt wingless signaling in Drosophila. Development 124, 3055-3064
24. Lin, X. et al. (1999) Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development. Development 126, 3715-3723
25. Forsberg, E. et al. (1999) Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme. Nature 400, 773-776
26. Humphries, D.E. et al. (1999) Heparin is essential forthe storage of specific granule proteases in mast cells. Nature 400, 769-772
27. Bellaiche, Y. et al. (1998) Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. Nature 394, 85-88
28. McCormick, C. et al. (1999) New perspectives on the molecular basis of hereditary bone tumours. Mol. Med. Today 5, 481-486
29. Toyoda, H. et al. (1999) Structural analysis of glycosaminoglycans in Drosophila and C. elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo. J. Biol. Chem. 275, 2269-2275
30. The, I. et al. (1999) Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan. Mol. Cell 4, 633-639
31. Kooyman, D.L. et al. (1995) In vivo transfer of GPI-linked complement restriction factors from erythrocytes to the endothelium. Science 269, 89-92
32. Mahley, R.W. and Ji, Z.S. (1999) Remnant lipoprotein metabolism: Key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E. J. Lipid Res. 40, 1-16
33. Bejsovec, A. and Wieschaus, E. (1995) Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface. Genetics 139, 309-320
34. Moline, M.M. et al. (1999) Directionality of wingless protein transport influences epidermal patterning in the Drosophila embryo. Development 126, 4375-4384
35. Sanson, B. et al. (1999) Engrailed and hedgehog make the range of wingless asymmetric in Drosophila embryos. Cell 98, 207-216
36. Kobayashi, M. et al. (1997) Molecular cloning and expression of Chinese hamster ovary cell heparan-sulfate 2-sulfotransferase. J. Biol. Chem. 272, 13980-13985
37. Bullock, S.L. et al. (1998) Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase. Genes Dev. 12, 1894-1906
38. Sen, J. et al. (1998) Spatially restricted expression of pipe in the Drosophila egg chamber defines embryonic dorsal-ventral polarity. Cell 95, 471-481
39. Rosenberg, R.D. et al. (1997) Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated? J. Clin. Invest. 100, 67-75
40. Ho, G. et al. (1997) Role of heparan sulfate proteoglycans in the uptake and degradation of tissue factor pathway inhibitor-coagulation factor Xa complexes. J. Biol. Chem. 272, 16838-16844
41. Song, H.H. et al. (1997) OCI-5/rat glypican-3 binds to fibroblast growth factor-2 but not to insulin-like growth factor-2. J. Biol. Chem. 272, 7574-7577
42. Padgett, R.W. et al. (1998) TGF-beta signaling, smads, and tumor suppressors. BioEssays 20, 382-390
43. Ramirez-Weber, F.A. and Kornberg, T.B. (1999) Cytonemes: Cellular processes that project to the principal signaling center in Drosophila imaginal discs. Cell 97, 599-607
44. Rogalski, T.M. et al. (1993) Products of the unc-52 gene in Caenorhabditis elegans are homologous to the core protein of the mammalian basement membrane heparan sulfate proteoglycan. Genes Dev. 7, 1471-1484.