Xenopus mad proteins transduce distinct subsets of signals for the TGFβ superfamily

Cell

Volumn 85, Issue 4, 1996, Pages 479-487

  Graff, Jonathan M ^a   Bansal, Anu ^a   Melton, Douglas A ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN;

ARTICLE; CAENORHABDITIS ELEGANS; DROSOPHILA; EMBRYO DEVELOPMENT; MOLECULAR CLONING; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FAMILY; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; XENOPUS;

EID: 0029940972     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81249-0     Document Type: Article

References (56)

1. Amaya, E., Musci, T.J., and Kirschner, M.W. (1991). Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell 66, 257-270.
2. Chen, R.H., Miettinen, P.J., Maruoka, E.M., Choy, L., and Derynck, R. (1995). A WD-domain protein that is associated with and phosphorylated by the type II TGF-β receptor. Nature 377, 548-552.
3. Cho, K.W.Y., Blumberg, B., Steinbeisser, H., and De Robertis, E.M. (1991). Molecular nature of Spemann's organizer: the role of Xenopus homeobox gene goosecoid. Cell 67, 1111-1120.
4. Christian, J.L., McMahon, J.A., McMahon, A.P., and Moon, R.T. (1991). Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm inducing factors may play a role in ventral mesodermal patterning during embryogenesis. Development 111, 1045-1056.
5. Dale, L., Howes, G., Price, B.M.J., and Smith, J.C. (1992). Bone morphogenetic protein 4: aventralizing factor in Xenopus development. Development 115, 573-585.
6. Dale, L., Matthews, G., and Colman, A. (1993). Secretion and mesoderm-inducing activity of the TGF-β-related domain of Xenopus Vg 1. EMBO J. 12, 4471-4480.
7. Derynck, R. (1994).TGF-β-receptor-mediated signaling.Trends Biochem. Sci. 19, 548-553.
8. Evans, J.P., and Kay, B. (1991). Biochemical fractionation of oocytes. Meth. Cell Biol. 36, 133-148.
9. Graft, J.M., Thies, R.S., Song, J.J., Celeste, A.J., and Melton, D.A. (1994). Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo. Cell 79, 169-179.
10. Green, J.B.A., Howes, G., Symes, K., Cooke, J., and Smith, J.C. (1990). The biological effects of XTC-MIF: quantitative comparison with Xenopus bFGF. Development 108, 173-183.
11. Green, J.B.A., New, H.V., and Smith, J.C. (1992). Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm. Cell 71, 731-739.
12. Hahn, S., Schutte, M., Hogque, A., Moskaluk, C., da Costa, L., Rozenblum, E., Weinstein, C., Fischer, A., Yeo, C., Hruban, R., and Kern, S. (1996). DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271, 350-353.
13. Hawley, S.H.B., Wunnenberg-Stapleton, K., Hasimoto, C., Laurent, M.N., Watabe, T., Blumberg, B., and Cho, K.W.Y. (1995). Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction. Genes Dev. 9, 2923-2935.
14. He, X., Saint-Jeannet, J.P., Woodgett, J.R., Varmus, H.E., and Dawid, I.B. (1995). Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature 374, 617-622.
15. Hemmati-Brivanlou, A., and Melton, D.A. (1992). A truncated activin receptor dominantly inhibits mesoderm induction and formation of axial structures in Xenopus embryos. Nature 359, 609-614.
16. Hemmati-Brivanlou, A., and Thomsen, G.H. (1995). Ventral mesodermal patterning in Xenopus embryos: expression patterns and activities of BMP-2 and BMP-4. Dev. Genet. 17, 78-89.
17. Hemmati-Brivanlou, A., Frank, D., Bolce, M.E., Brown, R.D., Sive, H.L., and Harland, R.M. (1990). Localization of specific mRNAs in Xenopus embryos by whole-mount in situ hybridization. Development 110, 325-330.
18. Herskowitz, I. (1987). Functional inactivation of genes by dominant negative mutations. Nature 329, 219-222.
19. Jones, C.M., Lyons, K.M., Lapan, P.M., Wright, C.V.E., and Hogan, B.J.M. (1992). DVR-4 (bone morphogenetic protein-4) as a posteroventralizing factor in Xenopus mesoderm induction. Development 115, 639-647.
20. Jones, C.M., Kuehn, M.R., Hogan, B.L.M., Smith, J.C., and Wright, C.V.E. (1995). Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. Development 121, 3651-3662.
21. Kessler, D.S.,and Melton, D.A. (1995). Induction of dorsal mesoderm by soluble, mature Vg1 protein. Development 121, 2155-2164.
22. Kingsley, D. (1994). The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8, 133-146.
23. Kintner, C.R., and Melton, D.A. (1987). Expression of Xenopus N-CAM RNA in ectoderm is an early response to neural induction. Development 99, 311-325.
24. Koster, M., Plessow, S., Clement, J.H., Lorenz, A., Tiedemann, H., and Knochel, W. (1991). Bone morphogenetic protein 4 (BMP-4), a member of the TGF-β family, in early embryos of Xenopus laevis. analysis of mesoderm inducing activity. Mech. Dev. 33, 191-200.
25. Krieg, P.A., and Melton, D.A. (1987). In vitro RNAsynthesis with SP6 RNA polymerase. Meth. Enzymol. 155, 397-415.
26. Krieg, P.A., Varnum, S., Wormington, M., and Melton, D.A. (1989). The mRNA encoding elongation factor 1α (EF-1α) is a major transcript at the mid blastula transition in Xenopus. Dev. Biol. 133, 93-100.
27. Lee, J.E., Hollenberg, S.M., Snider, L., Turner, D.L., Lipnick, N., and Weintraub, H. (1995). Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science 268, 836-844.
28. Massagué, J., Attisano, L., and Wrana, J.L. (1994). The TGF-β family and its composite receptors. Trends Cell Biol. 4, 172-178.
29. Mathews, L.S. (1994). Activin receptors and cellular signaling by the receptor serine kinase family. Endocr. Rev. 15, 310-325.
30. Mohun, T.J., Brennan, S., Dathan, N., Fairman, S., and Gurdon, J.B. (1984). Cell type specific activation of actin genes in the early amphibian embryo. Nature 311, 716-721.
31. Newfeld, S.J., Chartoff, E.H., Graft, J.M., Melton, D.A., and Gelbart, W.M. (1996). Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-β-responsive cells. Development, in press.
32. Nieuwkoop, P.D., and Faber, J. (1967). Normal Table of Xenopus laevis (Daudin) (Amsterdam: North Holland Publishing Company).
33. Pierce, S.B., and Kimelman, D. (1995). Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3. Development 121, 755-765.
34. Raftery, L.A., Twobly, V., Wharton, K., and Gelbart, W.M. (1995). Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila. Genetics 139, 241-254.
35. Rebagliati, M.R., Weeks, D.L., Harvey, R.P., and Melton, D.A. (1985). Identification and cloning of localized maternal mRNAs from Xenopus eggs. Cell 42, 769-777.
36. Rosa, F., Roberts, A.B., Danielpour, D., Dart, L.L., Sporn, M.B., and Dawid, I.B. (1988). Mesoderm induction in amphibians: the role of TGF-β2-like factors. Science 239, 783-785.
37. Sasai, Y., Lu, B., Steinbeisser, H., and DeRobertis, E.M. (1995). Regulation of neural induction by the Chd and BMP-4 antagonistic patterning signals in Xenopus. Nature 376, 333-336.
38. Savage, C., Das, P., Finelli, A., Townsend, S., Sun, C., Baird, S., and Padgett, R. (1996). Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor β pathway components. Proc. Natl. Acad. Sci. USA 93, 7790-7794.
39. Schmidt, J.E., Suzuki, A., Ueno, N., and Kimelman, D. (1995). Localized BMP-4 mediates dorsal/ventral patterning in the early Xenopus embryo. Dev. Biol. 169, 37-50.
40. Schulte-Merker, S., Smith, J.C., and Dale, L. (1994). Effects of truncated activin and FGF receptors and of follistatin on the inducing activities of BVg1 and activin: does activin play a role in mesoderm induction? EMBO J. 13, 3533-3541.
41. Sekelsky, J.J., Newfeld, S.J., Raftery, L.A., Chartoff, E.H., and Gelbart, W.M. (1995). Genetic characterization and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 139, 1347-1358.
42. Smith, J.C., Price, B.M.J., Green, J.B.A., Weigel, D., and Herrmann, B.G. (1991a). Expression of a Xenopus homolog of Brachyury (T) in an immediate-early response to mesoderm induction. Cell 67, 79-87.
43. Smith, L.D., Xu, W., and Varnold, R.L. (1991 b). Oogenesis and oocyte isolation. Meth. Cell Biol. 36, 45-60.
44. Smith, W.C., and Harland, R.M. (1991). Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center. Cell 67, 753-765.
45. Sokol, S.Y., Klingensmith, J., Perrimon, N., and Itoh, K. (1995). Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled. Development 121, 1637-1647.
46. Suzuki, A., Thies, R.S., Yamaji, N., Song, J.J., Wozney, J.M., Murakami, K., and Ueno, N. (1994). A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo. Proc. Natl. Acad. Sci. USA 91, 10255-10259.
47. Thomsen, G.H., and Melton, D.A. (1993). Processed Vg1 protein is an axial mesoderm inducerin Xenopus. Cell 74, 433-441.
48. Thomsen, G., Woolf, T., Whitman, M., Sokol, S., Vaughan, J., Vale, W., and Melton, D.A. (1990). Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures. Cell 63, 485-493.
49. Umbhauer, M., Marshall, C.J., Mason, C.S., Old, R.W., and Smith, J.C. (1995). Mesoderm induction in Xenopus caused by activation of MAP kinase. Nature 376, 58-62.
50. Verma, I.M., Stevenson, J.K., Schwarz, E.M., Antwerp, D.V., and Miyamoto, S. (1995). Rel/NF-κB/κB family: intimate tales of association and dissociation. Genes Dev. 9, 2723-2735.
51. Wall, N.A., and Hogan, B.L.M. (1994). TGF-β related genes in development. Curr. Opin. Genet. Dev. 4, 517-522.
52. Wang, T., Donahoe, P.K., and Zervos, A.S. (1994). Specific interaction of type I receptors of the TGF-β family with the immunophilin FKBP-12. Science 265, 674-676.
53. Wilson, P.A., and Hemmati-Brivanlou, A. (1995). Induction of epidermis and inhibition of neural fate by BMP-4. Nature 376, 331-333.
54. Wilson, P.A., and Melton, D.A. (1994). Mesodermal patterning by an inducer gradient depends on secondary cell-cell communication. Curr. Biol. 4, 676-686.
55. Wrana, J.L., Attisano, L., Wieser, R., Ventura, F., and Massague, J. (1994). Mechanism of activation of the TGF-β receptor. Nature 370, 341-347.
56. Yamaguchi, K., Shirakabe, K., Shibuya, H., Irie, K., Oishi, I., Ueno, N., Taniguchi, T., Nishida, E., and Matsumoto, K. (1995). Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science 270, 2008-2011.