Direct and long-range action of a wingless morphogen gradient

Cell

Volumn 87, Issue 5, 1996, Pages 833-844

  Zecca, Myriam ^a   Basler, Konrad ^a   Struhl, Gary ^b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DROSOPHILA; EVOLUTION; FORELIMB; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENE TARGETING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; SPECIES DIFFERENTIATION; TRANSCRIPTION REGULATION;

ARMADILLO;

EID: 0030606264     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81991-1     Document Type: Article

References (68)

1. Basler, K., and Struhl, G. (1994). Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein. Nature 368, 208-214.
2. Bejsovec, A., and Martinez-Arias, A. (1991). Roles of wingless in patterning the larval epidermis of Drosophila. Development 113, 471-485.
3. Blair, S. (1992). shaggy (zeste-white 3) and the formation of supernumerary bristle precursors in the developing wing blade of Drosophila. Dev. Biol. 152, 263-278.
4. Blair, S.S. (1993). Mechanisms of compartment formation: evidence that non-proliferating cells do not play a critical role in defining the D/V lineage restriction in the developing wing of Drosophila. Development 119, 339-351.
5. Boulianne, G.L., de la Concha, A., Campos-Ortega, J.A., Jan, L.Y., and Jan, Y.N. (1991). The Drosophila neurogenetic gene neuralized encodes a novel protein and is expressed in precursors of larval and adult neurons. EMBO J. 10, 2975-2983.
6. Brand, A.H., and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
7. Brönner, G., and Jäckle, H. (1991). Control and function of terminal gap gene activity in the posterior pole region of the Drosophila embryo. Mech. Dev. 35, 205-211.
8. Bryant, P.J. (1970). Cell lineage relationships in the imaginal wing disc of Drosophila melanogaster. Dev. Biol. 22, 389-411.
9. Carroll, S.B., Gates, J., Keys, D.N., Paddock, S.W., Panganiban, G. E.F., Selegue, J.E., and Williams, J.A. (1994). Pattern formation and eyespot determination in butterfly wings. Science 265, 109-114.
10. Casanova, J., Furriols, M., McCormick, C.A., and Struhl, G. (1995). Similarities between trunk and spätzle, putative extracellular ligands specifying body pattern in Drosophila. Genes Dev. 9, 2539-2544.
11. Cohen, S.M., Bronner, G., Kuttner, F., Jurgens, G., and Jackle, H. (1989). Distal-less encodes a homoeodomain protein required for limb development in Drosophila. Nature 338, 432-434.
12. Couso, J.P., Bishop, S.A., and Martinez Arias, A. (1994). The wingless signalling pathway and the patterning of the wing margin in Drosophila. Development 120, 621-636.
13. Diaz-Benjumea, F.J., and Cohen, S.M. (1994). wingless acts through the shaggylzeste-white 3 kinase to direct dorsal-ventral axis formation in the Drosophila leg. Development 120, 1661-1668.
14. Diaz-Benjumea, F.J., and Cohen, S.M. (1995). Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing. Development 121, 4215-4225.
15. Dietrich, U., and Campos-Ortega, J.A. (1984). The expression of neurogenic loci in imaginal epidermal cells of Drosophila melanogaster. J. Neurogenet. 1, 315-332.
16. DiNardo, S., Sher, E., Heemskerk, J.J., Kassis, J.A., and O'Farrell, P.H. (1988). Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis. Nature 332, 604-609.
17. Fischer, J.A., Giniger, E., Maniatis, T., and Ptashne, M. (1988). GAL4 activates transcription in Drosophila. Nature 332, 853-855.
18. Garcia-Bellido, A., Ripoll, P., and Morata, G. (1973). Developmental compartmentalisation of the wing disk of Drosophila. Nature New Biol. 245, 251-253.
19. Golic, K. (1991). Site-specific recombination between homologous chromosomes in Drosophila. Science 252, 958-961.
20. Grimm, S., and Pflugfelder, G.O. (1996). Control of the gene optomotor-blind in Drosophila wing development by decapentaplegic and wingless. Science 271, 1601-1604.
21. Hama, C., Ali, Z., and Kornberg, T.B. (1990). Region-specific recombination and expression are directed by portions of the Drosophila engrailed promoter. Genes Dev. 4, 1079-1093.
22. Heemskerk, J., DiNardo, S., Kostriken, R., and OFarrell, P.H. (1991). Multiple modes of engrailed regulation in the progression towards cell fate determination. Nature 352, 404-410.
23. Hoppler, S., and Bienz, M. (1995). Two different thresholds of wingless signalling with distinct develomental consequences in the Drosophila midgut. EMBO J. 14, 5016-5026.
24. Hortsch, M., Patel, N.H., Bieber, A.J., Traquina, Z.R., and Goodman, C.S. (1990). Drosophila neurotactin, a surface glycoprotein with homology to serine esterases, is dynamically expressed during embryogenesis. Development 110, 1327-1340.
25. Jiang, J., and Struhl, G. (1995). Protein kinase A and Hedgehog signalling in Drosophila limb development. Cell 80, 563-572.
26. Kim, J., Irvine, K.D., and Carroll, S. (1995). Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. Cell 82, 795-802.
27. Kim, J., Sebring, A., Esch, J., Kraus, M.E., Vorwerk, K., Magee, J., and Carroll, S.B. (1996). Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene. Nature 382, 133-138.
28. Lecuit, T., Brook, W.J., Ng, M., Callega, M., Sun, H., and Cohen, S.M. (1996). Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing. Nature 381, 387-393.
29. Lepage, T., Cohen, S.M., Diaz-Benjumea, F.J., and Parkhurst, S.M. (1995). Signal transduction by cAMP-dependent protein kinase A in Drosophila limb patterning. Nature 373, 711-715.
30. Li, W., Ohlmeyer, J.T., Lane, M.E., and Kalderon, D. (1995). Function of protein kinase A in hedghehog signal transduction and Drosophila imaginal disc development. Cell 80, 553-562.
31. Martinez-Arias, A., Baker, N.E., and Ingham, P.W. (1988). Role of segment polarity genes in the definition and maintenance of cell states in the Drosophila embryo. Development 103, 157-170.
32. McMahon, A.P., and Moon, R.T. (1989). int-1 - a proto-oncogene involved in cell signalling. Development 107, 161-167.
33. Morgan, T.H. (1897). Regeneration in Allolobophora foetida. Roux's Arch. Dev. Biol. 5, 570-586.
34. Morisato, D., and Anderson, K.V. (1994). The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorso-ventral pattern of the Drosophila embryo. Cell 76, 677-688.
35. Nellen, D., Burke, R., Struhl, G., and Basler, K. (1996). Direct and long-range action of a DPP morphogen gradient. Cell 85, 357-368.
36. Neumann, C.J., and Cohen, S.M. (1996). Distinct mitogenic and cell fate specification functions of wingless in different regions of the wing. Development 122, 1781-1789.
37. Noordermeer, J., Johnston, P., Rijsewijk, F., Nusse, R., and Lawrence, P.A. (1992). The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo. Development 116, 711-719.
38. Nusse, R., and Varmus, H.E. (1992). Wnt genes. Cell 69, 1073-1087.
39. Nüsslein-Volhard, C., and Wieschaus, E. (1980). Mutations affecting segment number and polarity in Drosophila. Nature 287, 795-801.
40. Pan, D., and Rubin, G.M. (1995). cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in Drosophila imaginal discs. Cell 80, 543-552.
41. Parkin, N.T., Kitajewski, J., and Varmus, H.E. (1993). Activity of Wnt-1 as a transmembrane protein. Genes Dev. 7, 2181-2193.
42. Peifer, M., Rauskolb, C., Williams, M., Riggleman, B., and Wieschaus, E. (1991). The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation. Development 111, 1029-1043.
43. Peifer, M., and Wieschaus, E. (1990). The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin. Cell 63, 1167-1176.
44. Phillips, R.G., and Whittle, J.R.S. (1993). wingless expression mediates determination of peripheral nervous system elements in late stages of Drosophila wing disc development. Development 118, 427-436.
45. Pignoni, F., Balderelli, R.M., Steingrimsson, E., Diaz, R.J., Patapoutian, A., Merriam, J.R., and Lengyel, J.A. (1990). The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily. Cell 62, 151-163.
46. Roelink, H. (1995). Tripartite signaling of pattern: interactions between Hedgehogs, BMPs and Wnts in the control of vertebrate development. Curr. Opin. Neurobiol. 6, 33-40.
47. Roth, S., Stein, D., and Nüsslein-Volhard, C. (1989). A gradient of nuclear localization of the dorsal protein determines dorso-ventral pattern in the Drosophila embryo. Cell 59, 1189-1202.
48. Rulifson, E.J., and Blair, S.S. (1995). Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogensis in Drosophila. Development 121, 2813-1824.
49. Rushlow, C.A., Han, K., Manley, J.L., and Levine, M. (1989). The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila. Cell 59, 1165-1177.
50. Slack, J.M.W. (1987). Morphogenetic gradients - past and present. Trends Biochem. 12, 200-204.
51. Spemann, H. (1938). Embryonic Development and Induction (New Haven, Connecticut: Yale University Press).
52. Spradling, A.C., Stern, D.M., Kiss, I., Roote, J., Laverty,T., and Rubin, G.M. (1995). Gene disruptions using P transposable elements: an integral component of the Drosophila genome project. Proc. Natl. Acad. Sci. USA 92, 10824-10830.
53. Steward, R. (1989). Relocalization of the dorsal protein from the cytoplasm to the nucleus correlates with its function. Cell 59, 1179-1188.
54. Struhl, G., and Basler, K. (1993). Organizing activity of wingless protein in Drosophila. Cell 72, 527-540.
55. Treisman, J.E., and Rubin, G.M. (1995). wingless inhibits morphogenetic furrow movement in the Drosophila eye disc. Development 121, 3519-3527.
56. Turing, A. (1952). The chemical basis of morphogenesis. Philos. Trans. R. Soc. Lond. (B) 237, 37-72.
57. van-den-Heuvel, M., Nusse, R., Johnston, P., and Lawrence, P.A. (1989). Distribution of the wingless gene product in Drosophila embryos: a protein involved in cell-cell communication. Cell 59, 739-49.
58. Vincent, J. (1994). Morphogens dropping like flies? Trends Genet. 10, 383-385.
59. Vincent, J., and Lawrence, P.A. (1994). Drosophila wingless sustains engrailed expression only in adjoining cells: evidence from mosaic embryos. Cell 77, 909-915.
60. Wieschaus, E., and Riggleman, R. (1987). Autonomous requirements for the segment polarity gene armadillo during Drosophila embryogenesis. Cell 49, 177-84.
61. Wilder, E.L., and Perrimon, N. (1995). Dual functions of wingless in the Drosophila leg imaginal disc. 121, 477-488.
62. Williams, J.A., Bell, J.B., and Carroll, S.B. (1991). Control of Drosophila wing and haltere development by the nuclear vestigial gene product. Genes Dev. 5, 2481-2495.
63. Williams, J.A., Paddock, S.W., and Carroll, S.B. (1993). Pattern formation in a secondary field: a hierarchy of regulatory genes subdivides the developing Drosophila wing disc into discrete subregions. Development 117, 571-584.
64. Wilson, E.G. (1925). The Cell in Development and Inheritance (New York, New York: The Macmillan Company).
65. Wilson, I.A., Niman, H.L., Houghten, R.A., Cherenson, A.R., Connolly, M.L., and Lerner, R.A. (1984). The structure of an antigenic determinant in a protein. Cell 37, 767-778.
66. Xu, T., and Rubin, G.M. (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.
67. Yost, C., Torres, M., Miller, J.R., Huang, E., Kimmelman, D., and Moon, R.T. (1996). The axis-inducing activity, stability and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev. 10, 1443-1454.
68. Zecca, M., Basler, K., and Struhl, G. (1995). Sequential organizing activities of engrailed, hedgehog, and decapentaplegic in the Drosophila wing. Development 121, 2265-2278.