A Wnt signaling pathway controls Hox gene expression and neuroblast migration in C. elegans

Development

Volumn 126, Issue 1, 1999, Pages 37-49

  Maloof, Julin N ^a   Whangbo, Jennifer ^a   Harris, Jeanne M ^a,b   Jongeward, Gregg D ^a,c   Kenyon, Cynthia ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY   (United States)

^c UNIVERSITY OF THE PACIFIC   (United States)

Author keywords

C. elegans; Cell migration; Hox gene; Wnt signaling

Indexed keywords

BETA CATENIN; GLYCOPROTEIN;

ANIMAL CELL; ARTICLE; CAENORHABDITIS ELEGANS; CELL MIGRATION; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; NEUROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL MOVEMENT; CYTOSKELETAL PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOPROTEINS; HELMINTH PROTEINS; HOMEODOMAIN PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; NEURONS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

ANIMALIA; CAENORHABDITIS ELEGANS; INVERTEBRATA;

EID: 0032960350     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Adler, P. N. (1992). The genetic control of tissue polarity in Drosophila. BioEssays 14, 735-741.
2. Bhanot, P., Brink, M., Samos, C. H., Hsieh, J., Wang, Y., Macke, J. P., Andrew, D., Nathans, J. and Nusse, R. (1996). A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 382, 225-230.
3. Brannon, M., Gomperts, M., Sumoy, L, Moon, R. T., and Kimelman D. (1997). A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus. Genes Dev. 11, 2359-2370.
4. Brenner, S. (1974). The genetics of C. elegans. Genetics 77, 71-94.
5. Cadigan, K. M. and Nusse, R. (1997). Wnt signaling: a common theme in animal development. Genes Dev. 11, 3286-3305.
6. Castelli-Gair, J. and Akam, M. (1995). How the Hox gene Ultrabithorax specifies two different segments: the significance of spatial and temporal regulation within metameres. Development 121, 2973-2982.
7. Chisholm, A. (1991). Control of cell fate in the tail region of C. elegans by the gene egl-5. Development 111, 921-932.
8. Clark, S. G., Chisholm, A. D. and Horvitz, H. R. (1993). Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39. Cell 74, 43-55.
9. Costa, M., Weir, M., Coulson, A., Sulston, J. and Kenyon, C. (1988). Posterior pattern formation in C. elegans involves position-specific expression of a gene containing a homeobox. Cell 55, 747-756.
10. Cowing, D. W. and Kenyon, C. (1992). Expression of the homeotic gene mab-5 during Caenorhabditis elegans embryogenesis. Development 116, 481-490.
11. Desai, C., Garriga, G., MeIntire, S. L. and Horvitz, H. R. (1988). A genetic pathway for the development of the Caenorhabditis elegans HSN motor neurons. Nature 336, 638-646.
12. Eisenmann, D. M., Maloof, J. N., Simske, J. S., Kenyon, C. and Kim, S. K. (1998). The β-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during C. elegans vulval development. Development 125, 3667-3680.
13. Ferguson, E. L. and Horvitz, H. R. (1985). Identification and characterization of 22 genes that affect lhe vulval cell lineages of the nematode Caenorhabditis elegans. Genetics 110, 17-72.
14. Fire, A., Harrison, S. W. and Dixon, D. (1990). A modular set of lacZ fusion vectors for studying gene expression in Caenorhabditis elegans. Gene 93, 189-198.
15. Fixsen, W. D. (1985). The genetic control of hypodermal lineages during nematode develoment. PhD Thesis, Massachusetts Institue of Technology.
16. Frohman, M. A. (1993). Rapid amplification of complementary DNA ends for generation of full-length complementary DNAs: thermal RACE. Meth. Enzymol. 218, 340-356.
17. Gavin, B. J., McMahon, J. A. and McMahon, A. P. (1990). Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 4, 2319-2332.
18. Guo, C. (1995). mig-5, a gene that controls cell fate determination and cell migration in C. elegans, is a member of the dsh family. PhD Thesis. The Johns Hopkins University.
19. Han, M. (1997). Gut reaction to Wnt signaling in worms [comment]. Cell 90, 581-584.
20. Harris, J., Honigberg, L., Robinson, N. and Kenyon, C. (1996). Neuronal cell migration in C. elegans: regulation of Hox gene expression and cell position. Development 122, 3117-3131.
21. Hedgecock, E. M., Culotti, J. G., Hall, D. H. and Stern, B. D. (1987). Genetics of cell and axon migrations in Caenorhabditis elegans. Development 100, 365-382.
22. Herman, M. A., Vassilieva, L. L., Horvitz, H. R., Shaw, J. E. and Herman, R. K. (1995). The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously. Cell 83, 101-110.
23. Jiang, L. I. and Sternberg, P. W. (1998). Interactions of EGF, Wnt and HOM-C genes specify the P12 neuroectoblast fate in C. elegans. Development 125, 2337-2347.
24. Kenyon, C. (1986). A gene involved in the development of the posterior body region of C. elegans. Cell 46, 477-487.
25. Kenyon, C., Austin, J., Costa, M., Cowing, D. W., Harris, J. M., Honigberg, L., Hunter, C. P., Maloof, J. N., Muller-Immergluck, M. M., Salser, S. J., Waring, D. A., Wang, B. B. and Wrischnik, L. A. (1998). The dance of the Hox genes: patterning the anteroposterior body axis of C. elegans. Cold Spring Harbor Symp. Quant. Biol. (in press).
26. Maloof, J. N. and Kenyon, C. (1998). The Hox gene lin-39 is required during C. elegans vulval induction to select the outcome of Ras signaling. Development 125, 181-190.
27. Mello, C. C., Kramer, J. M., Stinchcomb, D. and Ambros, V. (1991). Efficient gene transfer in C elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 10, 3959-3970.
28. Miller, J. R. and Moon, R. T. (1996). Signal transduction through beta-catenin and specification of cell fate during embryogenesis. Genes Dev. 10, 2527-2539.
29. Munemitsu, S., Albert, I., Souza, B., Rubinfeld, B. and Polakis, P. (1995). Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc. Natl. Acad. Sci. USA 92, 3046-3050.
30. Nelson, C. E., Morgan, B. A., Burke, A. C., Laufer, E., DiMambro, E., Murtaugh, L. C., Gonzales, E., Tessarollo, L., Parada, L. F. and Tabin, C. (1996). Analysis of Hox gene expression in the chick limb bud. Development 122, 1449-1466.
31. Nusse, R. (1997). A versatile transcriptional effector of Wingless signaling. Cell 89, 321-323.
32. Orsulic, S. and Peifer, M. (1996). An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling. J. Cell Biol. 134, 1283-1300.
33. Pai, L. M., Orsulic, S., Bejsovec, A. and Peifer, M. (1997). Negative regulation of Armadillo, a Wingless effector in Drosophila. Development 124, 2255-2266.
34. Peifer, M., Sweeton, D., Casey, M. and Wieschaus, E. (1994). wingless signal and Zeste-white 3 kinase trigger opposing changes in intracellular distribution of Armadillo. Development 120, 369-380.
35. Pirrotta, V. (1997). PcG complexes and chromatin silencing. Curr. Opin. Genet. Dev. 7, 249-258.
36. Polakis, P. (1997). The adenomatous polyposis coli (APC) tumor suppressor. Biochim. Biophys. Acta 1332, F127-147.
37. Rijsekijk, F., Schuermann, M., Wagenaar, E., Parren, P., Weigel, D., and Nusse, R. (1987). The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless. Cell 50, 649-657.
38. Rocheleau, C. E., Downs, W. D., Lin, R., Wittmann, C., Bei, Y., Cha, Y. H., Ali, M., Priess, J. R. and Mello, C. C. (1997). Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos [see comments]. Cell 90, 707-716.
39. Rubinfeld, B., Albert, I., Porfiri, E., Fiol, C., Munemitsu, S. and Polakis, P. (1996). Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly [see comments]. Science 272, 1023-1026.
40. Salser, S. J. and Kenyon, C. (1992). Activation of a C. elegans Antennapedia homologue in migrating cells controls their direction of migration. Nature 355, 2558.
41. Salser, S. J. and Kenyon, C. (1996). A C. elegans Hox gene switches on, off, on and off again to regulate proliferation, differentiation and morphogenesis. Development 122, 1651-1661.
42. Sawa, H., Lobel, L. and Horvitz, H. R. (1996). The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein. Genes Dev 10, 2189-2197.
43. Siegfried, E., Chou, T. B. and Perrimon, N. (1992). Wingless signaling acts through zeste-white 3, the Drosophila homolog glycogen synthase kinase-3, to regulate engrailed and establish cell fate. Cell 71, 1167-1179.
44. Strome, S., Garvin, C., Paulsen, J., Capowski, E., Martin, P. and Beanan, M. (1994). Specification and development of the germline in Caenorhabditis elegans. Ciba Foundation Symp. 182, 31-45; Discussion 45-57.
45. Thorpe, C. J., Schlesinger, A., Carter, J. C. and Bowerman, B. (1997). Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm [see Comments]. Cell 90, 695-705.
46. Trent, C., Tsung, N. and Horvitz, H. (1983). Egg-laying defective mutants of the nematode C. elegans. Genetics 104, 619-647.
47. van de Wetering, M., Cavallo, R., Dooijes, D., van Beest, M., van Es, J., Loureiro, J., Ypma, A., Hursh, D., Jones, T., Bejsovec, A., Peifer, M., Mortin, M. and Clevers, H. (1997). Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 88, 789-799.
48. von Heijne, G. (1986). Net N-C charge imbalance may be important for signal sequence function in bacteria. J. Mol. Biol 192, 287-290.
49. Wang, B. B., Muller, I. M., Austin, J., Robinson, N. T., Chisholm, A. and Kenyon, C. (1993). A homeotic gene cluster patterns the anteroposterior body axis of C. elegans. Cell 74, 29-42.
50. Williams, B. D., Schrank, B., Huynh, C., Shownkeen, R. and Waterston, R. H. (1992). A genetic mapping system in Caenorhabditis elegans based on polymorphic sequence-tagged sites. Genetics 131, 609-624.
51. Wood, W. B. (1988). The Nematode Caenorhabditis elegans. Cold Spring Harbor Laboratory, New York.
52. Wrischnik, L. A. and Kenyon, C. J. (1997). The role of lin-22, a hairy/enhancer of split homolog, in patterning the peripheral nervous system of C. elegans. Development 124, 2875-2888.
53. Zeng, L., Fagotto, F., Zhang, T., Hsu, W., Vasicek, T. J., Perry, W. R., Lee, J. J., Tilghman, S. M., Gumbiner, B. M. and Costantini, F. (1997). The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell 90, 181-192.