Antiatherogenic effect of Pistacia lentiscus via GSH restoration and downregulation of CD36 mRNA expression

Atherosclerosis

Volumn 174, Issue 2, 2004, Pages 293-303

  Dedoussis, George V Z ^a   Kaliora, Andriana C ^a   Psarras, Stellios ^b   Chiou, Antonia ^a   Mylona, Anastasia ^a   Papadopoulos, Nikolaos G ^b   Andrikopoulos, Nikolaos K ^a  

^a HAROKOPIO UNIVERSITY   (Greece)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Apoptosis; GSH; oxLDL; P. lentiscus; PBMC; Phenolics; Triterpenes

Indexed keywords

ANTIOXIDANT; CD14 ANTIGEN; CD36 ANTIGEN; CELL PROTEIN; GLUTATHIONE; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; OXIDIZED LOW DENSITY LIPOPROTEIN; PISTACIA LENTISCUS EXTRACT; PLANT EXTRACT; RESIN; SCAVENGER RECEPTOR; TRITERPENOID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; ATHEROGENESIS; CELL CULTURE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG MECHANISM; FOAM CELL; GENE EXPRESSION REGULATION; GREECE; GROWTH INHIBITION; HUMAN; HUMAN CELL; MACROPHAGE; MOLECULAR MECHANICS; NECROSIS; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; PISTACIA LENTISCUS; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANTIGENS, CD36; ANTIOXIDANTS; ARTERIOSCLEROSIS; CELL SURVIVAL; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOWN-REGULATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GLUTATHIONE; HUMANS; LIPOPROTEINS, LDL; MONOCYTES; OXIDATIVE STRESS; PHYTOTHERAPY; PISTACIA; PLANT PREPARATIONS; POLYMERASE CHAIN REACTION; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY;

EID: 2342530964     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2004.02.011     Document Type: Article

References (33)

1. Henriksen T., Mahoney E., Steinberg D. Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells, recognition by receptors for acetylated low density lipoproteins. Proc. Natl. Acad. Sci. U.S.A. 78:1981;6499-6503
2. Steinberg D., Parthasarathy S., Carew T.E., Khoo J.C., Witztum J.L. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenesity. N. Engl. J. Med. 320:1989;915-924
3. Fuhrman B., Volkova N., Aviram M. Oxidative stress increases the expression of the CD36 scavenger receptor and the cellular uptake of oxidized low-density lipoprotein in macrophages from atherosclerotic mice, protective role of antioxidants and of paraoxonase. Atherosclerosis. 161:2002;307-316
4. Steinbrecher U.P. Receptors for oxidized low density lipoprotein. Biochim. Biophys. Acta. 1436:1999;279-298
5. Silverstein R., Febbraio L.M. CD36 and atherosclerosis. Curr. Opin. Lipidol. 11:2000;483-491
6. Yoshida H., Quehenberger O., Kondratenko N., Green S., Steinberg D. Minimally oxidized low-density lipoprotein increases expression of scavenger receptor A, CD36 and macrosialin in resident mouse peritoneal macrophages. Arterioscler Thromb. Vasc. Biol. 18:1998;794-802
7. Aviram M. Review on human studies on oxidative damage and antioxidant protection related to cardiovascular diseases. Free Radic. Res. 33:2000;S85-S97
8. Deckert V., Dersumaux C., Athias A., et al. Prevention of LDL α-tocopherol consumption, cholesterol oxidation, and vascular endothelium dysfanction by polyphenolic compounds from red wine. Atherosclerosis. 165:2002;41-50
9. Visioli F., Poli A., Galli C. Antioxidant and other biological activities of phenols from olives and olive oil. Med. Res. Rev. 22:2002;65-75
10. Andrikopoulos N.K., Kaliora A.C., Assimopoulou A.N., Papageorgiou V.P. Inhibitory activity of minor polyphenolic and nonpolyphenolic constituents of olive oil against in vitro low-density lipoprotein oxidation. J. Med. Food. 5:2002a;1-7
11. Andrikopoulos N.K., Kaliora A.C., Assimopoulou A.N., Papageorgiou V.P. Biological activity of some naturally occurring resins, gums and pigments against the in vitro LDL oxidation. Phytother. Res. 17:2003;501-507
12. Al-Said M.S., Aggel A.M., Parmar N., Tariq M. Evaluation of mastic, a crude drug obtained from Pistacia lentiscus for gastric and duodenal anti-ulcer activity. J. Ethnopharmacol. 15:1986;271-278
13. Huwez F.U., Thirlwell D., Al'Aldeen D.A.A. Mastic gum kills Helicobacter pylori. N Engl. J. Med. 339:1999;1946
14. Janakat S., Al-Merie H. Evaluation of hepatoprotective effect of Pistacia lentiscus, Phillyrea latifolia and Nicotiana glauca. J. Ethnopharmacol. 83:2002;135-138
15. Janciauskiene S., Moraga F., Lindgren S. C-terminal fragment of alpha1-antitrypsin activates human monocytes to a pro-inflammatory state through interactions with the CD36 scavenger receptor and LDL receptor. Atherosclerosis. 158:2001;41-51
16. Fortun A., Khalil A., Gagne D., et al. Monocytes influence the fate of T cells challenged with oxidised low density lipoproteins towards apoptosis or MHC-restricted proliferation. Atherosclerosis. 156:2001;11-21
17. Gutfinger T. Polyphenols in olive oil. J. Am. Oil Chem. Soc. 58:1981;966-968
18. Balla G., Jacob H.S., Eaton J.W., Vercellotti G.M. Hemin. A possible physiological mediator of low density lipoprotein oxidation and endothelial Injury. Arterioscler. Thromb. 11:1991;1700-1711
19. Baxevanis C.N., Reclos G.J., Gritzapis A.D., Dedoussis G.V.Z., Missitzis I., Papamichail M. Elevated prostaglandin E2 production by monocytes is responsible for the depressed levels of natural killer cell function in patients with breast cancer. Cancer. 72:1993;491-501
20. Dedoussis G.V.Z., Mouzaki A., Theodoropoulou M., et al. Endogenous interleukin 6 conveys resistance to cis-diamminedichloroplatinum-mediated apoptosis of the K562 human leukemic cell line. Exp. Cell Res. 249:1999;269-278
21. Devaraj S., Hugou I., Jialal I. α-Tocopherol decreases CD36 expression in human monocyte-derived macrophages. J. Lipid Res. 42:2001;521-527
22. Andrikopoulos N.K., Bruschweiler H., Felber H., Taeschler Ch. HPLC analysis of phenolic antioxidants, tocopherols and triglycerides. J. Am. Oil Chem. Soc. 68:1991;359-364
23. Kaliora A.C., Mylona A., Chiou A., Petsios D.G., Andrikopoulos N.K. Detection and identification of simple phenolics in Pistacia lentiscus resin, A.C. J. Liq. Chromatogr. Relat. Technol. 27:2004;289-300
24. Kerry N., Abbey M. Red wine and fractionated phenolic compounds prepared from red wine inhibit low density lipoprotein oxidation in vitro. Atherosclerosis. 135:1999;93-102
25. Andrikopoulos N.K., Kaliora A.C., Assimopoulou A.N., Papageorgiou V.P. Biological activity of saliva against in vitro LDL oxidation after chewing commercial chewing gums. Ital. J. Food Sci. 14:2002;279-289
26. Shen L., Sevanian A. oxLDL induces macrophage α-GCS+HS protein expression: a role for oxLDL-associated lipid hydroperoxide in GSH synthesis. J. Lipid Res. 42:2001;813-823
27. Ghibelli L., Fanelli C., Rotilio G., et al. Rescue of cells from apoptosis by inhibition of active GSH extrusion. FASEB J. 12:1998;479-486
28. Han C.Y., Pak Y.K. Oxidation-dependent effects of oxidized LDL: proliferation or cell death. Exp. Mol. Med. 31:1999;165-173
29. Feng J., Han J., Pearce S.F.A., et al. Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-α J. Lipid Res. 41:2000;688-696
30. Papageorgiou V.P., Bkolachristianopoulou M.N., Apazidou K.K., Psarros E.E. Gas chromatographic-mass spectroscopic analysis of the acidic triterpenic fraction of mastic gum. J. Chromatogr. A. 769:1997;263-273
31. Somova L.O., Nadar A., Rammanan P., Shode F.O. Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension. Phytomedicine. 10:2003a;115-121
32. Somova L.I., Shode F.O., Ramnanan P., Nadar A. Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies africana leaves. J. Ethnopharmacol. 84:2003;299-305
33. Ursini F., Tubaro F., Rong J., Sevanian A. Optimization of nutrition: polyphenols and vascular protection. Nutr. Rev. 57:1999;241-249