Control of mycotoxins in storage and techniques for their decontamination

Mycotoxins in Food: Detection and Control

Volumn , Issue , 2004, Pages 190-223

  Shapira, R ^a   Paster, N ^b  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b VOLCANI CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33748598293     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-1-85573-733-4.50014-8     Document Type: Chapter

References (226)

1. Anon (2001), Manual of the application of the HACCP system in mycotoxin prevention and control, FAO Food and Nutrition Paper No. 73, Rome, FAO
2. L Abrunhosa, R Serrs and A Venancio (2002) Biodegradation of ochratoxin A by fungi isolated from grapes. J. Agric. Food Chem. 50(25), 7493-7496
3. Aibara K and Miyaki K (1970), Aflatoxin and its radio-sensitivity, in Radiation Sensitivity of Toxins and Animal Poisons: Proceedings of a Panel Meeting, Bangkok, May 19-22, 1969, Vienna, IAEA, 49-62
4. J F Alberts, W C Gelderblom, P G Thiel, W F Marasas, D J Van Schalkwyk and Y Behrend (1990) Effects of temperature and incubation period on production of fumonisin B1 by. Fusarium moniliforme, Appl. Environ. Microbiol. 56(6), 1729-1733
5. T Altug, A E Yousef and E H Marth (1990) Degradation of aflatoxin B1 in dried figs by sodium bisulfite with or without heat, ultraviolet energy or hydrogen peroxide. J. Food Protect. 53(7), 581-582
6. M S Anderson, M F Dutton and K Harding (1979) Production and degradation of patulin by Paecilomyces species, a common contaminant of silage. J. Sci. Food Agric. 30(3), 229-232
7. K L Applegate and J R Chipley (1974) Effect of 60Co GI on aflatoxin B1 and B2 production by. Aspergillus flavus, Mycologia 66(3), 436-445
8. K L Applegate and J R Chipley (1976) Production of ochratoxin A by Aspergillus ochraceus NRRL-3174 before and after exposure to 60Co irradiation. Appl. Environ. Microbiol. 31(3), 349-353
9. N H Aziz, E S A Attia and S A Farag (1997) Effect of gamma-irradiation on the natural occurrence of Fusarium mycotoxins in wheat, flour and bread. Nahrung-Food 41(1), 34-37
10. R H Bailey, L F Kubena, R B Harvey, S A Buckley and G E Rottinghaus (1998) Efficacy of various inorganic sorbents to reduce the toxicity of aflatoxin and T-2 toxin in broiler chickens. Poult. Sci. 77(11), 1623-1630
11. S C Basappa and T Shantha (1996) Methods for detoxification of aflatoxins in foods and feeds - a critical appraisal. J. Food Sci. Technol. 33(21), 95-107
12. A Bata and R Lasztity (1999) Detoxification of mycotoxin-contaminated food and feed by microorganisms. Trends Food Sci. Technol. 10(6-7), 223-228
13. J Bauer, M Garies, W Detzler, B Gedek, K Heinritzi and G Kabilka (1987) Detoxification of mycotoxins in feedstuffs. Tierarztl Umschau. 42(1), 70-77
14. S Beeton and A T Bull (1989) Biotransformation and detoxification of T-2 toxin by soil and freshwater bacteria. Appl. Environ. Microbiol. 55(1), 190-197
15. G A Bennett, O L Shotwell and C W Hesseltine (1980) Destruction of zearalenone in contaminated corn. J. Am. Oil Chem. Soc. 57(8), 245-247
16. D Bhatnagar, E B Lillehoj and J W Bennett (1991) Biological detoxification of mycotoxins. J E Smith, R S Henderson, (Eds) Mycotoxins and Animal Foods. Boston: CRC Press 816-826
17. B A Blackwell, J T Gilliam, M E Savard, D J Miller and J P Duvick (1999) Oxidative deamination of hydrolyzed fumonisin B(1) (AP(1)) by cultures of. Exophiala spinifera, Nat. Toxins. 7(1), 31-38
18. J Bol and J E Smith (1989) Biotransformation of aflatoxin. Food Biotechnol. 3(2), 127-144
19. H Boudra, P Le Bars and J Le Bars (1995) Thermostability of ochratoxin A in wheat under two moisture conditions. Appl. Environ. Microbiol. 61(3), 1156-1158
20. L B Bullerman and T E Hartung (1975) Effect of low-level gamma irradiation on growth and patulin production by. Penicillium patulum, J. Food Sci. 40(1), 195-196
21. R Canela, R Pujol, N Sala and V Sanchis (1996) Fate of fumonisins B1 and B2 in steeped corn kernels. Food Addit. Contam. 13(5), 511-517
22. M M Castelo, S S Sumner and L B Bullerman (1998) Stability of fumonisins in thermally processed corn products. J. Food Protect. 61(8), 1030-1033
23. D Cazzaniga, J C Basilico, R J Gonzalez, R L Torres and D M de Greef (2001) Mycotoxins inactivation by extrusion cooking of corn flour. Lett. Appl. Microbiol. 33(2), 144-147
24. A B Chakrabarti (1981) Detoxification of corn. J. Food Protect. 44(1), 591-592
25. L L Charmley and D B Prelusky (1994) Decontamination of Fusarium mycotoxins. J D Miller, H L Trenholm, (Eds) Mycotoxins in Grain, Compounds Other than Aflatoxin St Paul, MN: Eagan Press 421-435
26. J Chelkowski, P Golinsky, B Godlewska, W Radomyska, K Szebiotko and M Wiewiorowska (1981) Mycotoxins in cereal grain. Part IV. Inactivation of ochratoxin A and other mycotoxins during ammoniation. Nahrung 25(7), 631-637
27. C M Christensen and R A Meronuck (1986) Quality Maintenance in Stored Grains and Seeds. Minneapolis, MN: University of Minnesota Press
28. C M Christensen and D B Sauer (1982) Microflora. C M Christensen, (Eds) Storage of Cereal Grains and their Products St Paul, MN: American Association of Cereal Chemists Inc. 219-241
29. F S Chu, C C Chang, S H Ashoor and N Prentice (1975) Stability of aflatoxin B1 and ochratoxin A in brewing. Appl. Microbiol. 29(3), 313-316
30. A Ciegler, E B Lillehoj, R E Peterson and H H Hall (1966) Microbial detoxification of aflatoxin. Appl. Microbiol. 14(6), 934-939
31. R J Cole and J W Dorner (1994) Extraction of aflatoxin from naturally contaminated peanuts with different solvents and solvent/peanut ratios. J. Am. Oil Anal. Chem. 77(6), 1509-1511
32. L M Cote, A M Dahlem, T Yoshizawa, S P Swanson and W B Buck (1986) Excretion of deoxynivalenol and its metabolite in milk, urine and feces of lactating dairy cows. J. Dairy Sci. 69(9), 2416-2433
33. P J Cotty (1994) Influence of field application of an atoxigenic strain of Aspergillus flavus on the populations of A. flavus infecting cotton bolls and on aflatoxin content of cottonseed. Phytopathology 84(11), 1270
34. A F Cucullu, L S Lee, W A Pons Jr and J B Stanely (1976) Ammoniation of aflatoxin B1: isolation and characterization of a product with molecular weight 206. J. Agric. Food Chem. 24(2), 408-410
35. H Dalboge (1997) Expression cloning of fungal enzymes genes; a novel approach for efficient isolation of enzyme gene of industrial relevance. FEMS Microbiol. Rev. 21(1), 29-42
36. S Dänicke (2002) Prevention and control of mycotoxins in the poultry production chain: a European view. World's Poult. Sci. 58(4), 451-467
37. J N Davidson, J G Babish, K A Delaney, D R Taylor and T D Phillips (1987) Hydrated sodium calcium aluminosilicate decreases the bioavailability of aflatoxin in chicken. Poult. Sci. 66(Suppl. 1), 89
38. W J Decker and D G Corby (1980) Activated charcoal absorbs aflatoxin B1. Vet. Human Toxicol. 22(6), 388-389
39. M P Doyle and E H Marth (1978) Bisulfite degrades aflatoxin - effect of temperature and concentration of bisulfite. J. Food Protect. 41(10), 774-780
40. M P Doyle and E H Marth (1978) Aflatoxin is degraded by mycelia from toxigenic and nontoxigenic strains of aspergilli grown on different substrates. Mycopathologia 63(3), 145-153
41. M P Doyle and E H Marth (1978) Degradation of aflatoxin by lactoperoxidase. Z. Lebensum Unters Forsch. 166(5), 271-273
42. M P Doyle and E H Marth (1979) Peroxidase activity in mycelia of Aspergillus parasiticus that degrade aflatoxin. Eur. J. Appl. Microbiol. 7(2), 211-217
43. M P Doyle, R S Appelbaum, R E Brackett and E M Marth (1982) Physical, chemical and biological degradation of mycotoxins in foods and agricultural commodities. J. Food Protect. 45(10), 964-971
44. M F Dutton, K Westlake and M S Anderson (1984) The interaction between additives, yeast and patulin production in grass-silage. Mycopathologia 87(1-2), 29-33
45. Duvick J (1994), Isolation of fumonisin-metabolizing fungi from maize seed. in: 5th International Mycological Congress, Vancouver, University of British Columbia, 56
46. Duvick J and Rodd T A (1998), Zearalenone detoxification compositions and methods, US Patent 5, 846, 812, Pioneer Hi-Bred Int. (USA)
47. J Duvick, T Rodd, J Maddox and J Gilliam (1998) Detoxification of mycotoxins in planta as a strategy for improving grain quality and disease resistance: identification of fumonisin-degrading microbes from maize. K Kohmoto, O C Yoder, (Eds) Molecular Genetics of Host-specific Toxins in Plant Disease. Developments in Plant Pathology vol 13 Dordrecht: Kluwer Academic Publishers 369-382
48. T S Edrington, L F Kubena, R B Harvey and G E Rottinghaus (1997) Influence of a superactivated charcoal on the toxic effects of aflatoxins or T-2 toxin in growing broilers. Poultry Sci. 79(9), 1205-1211
49. A A El-Banna and P M Scott (1983) Fate of mycotoxins during processing of foodstuffs. I. Aflatoxin B1 during making of Egyptian bread. J. Food Protect. 46(4), 301-304
50. A A El-Banna, P Y Lau and P M Scott (1983) Fate of mycotoxins during processing of foodstuffs. II. Deoxynivalenol (vomitoxin) during making of Egyptian bread. J. Food Protect. 46(6), 484-486
51. R Elias-Orozco, A Castellanos-Nava, M Gaytan-Martinez, J D Figueroa-Cardenas and G Loarca-Pina (2002) Comparison of nixtamalization and extrusion processes for a reduction in aflatoxin content. Food Adda. Contam. 19(9), 878-885
52. W O Ellis, J P Smith, B K Simpson and J H Oldham (1991) Aflatoxin in food: occurrence, biosynthesis, and methods of control. Crit. Rev. Food Sci. 30(4), 403-439
53. H El-Nezami, P Kankaanpaa, S Salminen and J Ahokas (1998) Ability of lactic acid bacteria to bind a common food carcinogen, aflatoxin B-1. Food Chem. Toxicol. 36(4), 321-326
54. H El-Nezami, P Kankaanpaa, S Salminen and J Ahokas (1998) Physicochemical alterations enhance the ability of dairy strains of lactic acid bacteria to remove aflatoxin from contaminated media. J. Food Protect. 61(4), 466-468
55. H El-Nezami, H Mykkanen, P Kankaanpaa, S Salminen and J Ahokas (2000) Ability of Lactobacillus and Propionibacterium strains to remove aflatoxin B1 from the chicken duodenum. J. Food Protect. 63(4), 549-552
56. H El-Nezami, N Polychronaki, S Salminen and H Mykkanen (2002) Binding rather than metabolism may explain the interaction of two food-grade Lactobacillus strains with zearalenone and its derivative α-zearalenol. Appl. Environ. Microbiol. 68(7), 3545-3549
57. S El-Sharkawy and H K Abbas (1991) Metabolism of T-2 toxin by Mucor and Aspergillus sp. Acta Pharm. Jugosl. 41(3), 191-201
58. S El-Sharkawy and Y Abul-Hajj (1987) Microbial transformation of zearalenone. 1. Formation of zearalenone 4-O-β-glucoside. J. Nat. Prod. 50(3), 520-521
59. S El-Sharkawy and Y Abul-Hajj (1987) Microbial transformation of zearalenone. 2. Reduction, hydroxylation, and methylation products. J. Org. Chem. 53(3), 515-519
60. S El-Sharkawy and Y Abul-Hajj (1988) Microbial cleavage of zearalenone. Xenobiotica 18(4), 365-371
61. G Engelhardt, G Zill, B Wohner and P R Walhllnofer (1988) Transformation of the Fusarium mycotoxin zearalenone in maize cell suspension cultures. Naturwissenschaften 75(6), 309-310
62. R S Farag, M M Rashed and A A Abo Hgger (1996) Aflatoxin destruction by microwave heating. Int. J. Sci. Nutr. 47(3), 197-208
63. M K Faraj, J E Smith and G Harran (1993) Aflatoxin biodegradation: effect of temperature and microbes. Mycol. Res. 97(11), 1388-1392
64. G Feuerstein, J A Powell, A T Knower and K W Hunter (1988) Monoclonal antibodies to T-2 toxin - in vitro neutralization of protein synthesis inhibition and protection of rats against lethal toxemia. J. Clin. Invest. 76(6), 2134-2138
65. S Freimund, M Sauter and P Rys (2003) Efficient adsorption of the mycotoxins zearalenone and T-2 toxin on a modified yeast glucan. J. Environ. Sci. Health. B38(3), 243-255
66. M Fujita and T Yoshizawa (1989) Induction of phytoalexins by various mycotoxins and metabolism of mycotoxins in sweet potato root tissues. J. Food Hyg. Soc. Jpn. 30(6), 501-505
67. F Galvano, A Pietri, T Bertuzzi, M Bogano, L Chies, A De Angelis and M Galvano (1997) Activated carbons: in vitro affinity for fumonisin B1 and relation of adsorption ability to physicochemical parameters. J. Food Protect. 60(8), 985-991
68. M Gareis, J Bauer, J Thiem, G Plank, S Grabley and B Gedek (1990) Cleavage of zearalenone-glycoside, a masked mycotoxin, during digestion in swine. J. Vet. Med. B. 37(3), 236-240
69. W C Gelderblom, M E Cawood, S D Snyman, R Vleggaar and W F Marasas (1993) Structure-activity relationships of fumonisins in short-term carcinogenesis and cytotoxicity assays. Food Chem. Toxicol. 31(6), 407-414
70. J Gilbert (1995) Analysis of mycotoxins in food and feed; certification of DON in wheat and maize. Nat. Toxins. 3(4), 263-268
71. L A Goldblatt (1971) Control and removal of aflatoxin. J. Am. Oil Chem. Soc. 48(10), 605-610
72. L A Goldblatt and F G Dollear (1977) Detoxification of contaminated crops. J Rodricks, C W Hesseltine, M A Mehlman, (Eds) Mycotoxins in Human and Animal Health. Park Forest South, IL: Pathotox Publishers, Inc. 139-150
73. Goldblatt L A and Robertson J A Jr (1970), Process for removing aflatoxin from peanuts, US Patent 3, 515, 736
74. W N Hagler Jr, J R Hutchins and P B Hamilton (1982) Destruction of aflatoxin B1 in corn with some sodium bisulfite. J. Food Protect. 45(14), 1287-1291
75. O M Hale and D M Wilson (1979) Performance of pigs on diet containing heated or unheated corn with or without aflatoxin. J. Anim. Sci. 48(6), 1394-1400
76. A B Hamid and J E Smith (1987) Degradation of aflatoxin by. Aspergillus flavus, J. Gen. Microbiol. 133(8), 2023-2029
77. D Y Y Hao and R E Brackett (1988) Removal of aflatoxin B1 from peanut milk inoculated with. Flavobacterium auranotiacum, J. Food Sci. 53(5), 1384-1386
78. J Harwig, P M Scott, B P C Kennedy and Y-K Chen (1973) Disappearance of patulin from apple juice fermented by Saccharomyces spp. Can. J. Food Sci. Tech. 6(1), 45-46
79. J Harwig, B J Blanchfield and G Jarvis (1977) Effect of water activity on disappearance of patulin and citrinin from grains. J. Food Sci. 42(5), 1225-1228
80. C A Haskard, C Binnion and J Ahokas (2000) Factors affecting the sequestration of aflatoxin by Lactobacillus rhamnosus strain GG. Chem-Biol Inter. 128(1), 39-49
81. C A Haskard, H El-Nazemi, P Kankaanpaa, S Salminen and J T Ahokas (2001) Surface binding of aflatoxin B1 by lactic acid bacteria. Appl. Environ. Microbiol. 67(7), 3086-3091
82. P He, L G Young and C Forsberg (1992) Microbial transformation of deoxynivalenol (vomitoxin). Appl. Environ. Microbiol. 58(12), 3857-3863
83. S Hendrich, K A Miller, T M Wilson and P A Murphy (1993) Toxicity of Fusarium proliferatum-fermented nixtamalized corn-based diets fed to rats: effect of nutritional status. J. Agr. Food Chem. 41(10), 1649-1654
84. Henry S H, Whitaker T, Rabbani I, Bowers J, Park D, Price W, Bosch F X, Pennington J, Verger P, Yoshizawa T, van Egmond H, Jonker M A and Coker R (2001), Aflatoxin M1, in Safety Evaluation of Certain Mycotoxins in Food, WHO Additive Series, 47: 1-103
85. H Hooshmand and C F Klopfenstein (1995) Effect of gamma-irradiation on mycotoxin disappearance and amino-acid contents of corn, wheat, and soybeans with different moisture contents. Plant Food Human Nutr. 47(3), 227-238
86. K Hult, A Teiling and S Gatenbeck (1976) Degradation of ochratoxin A by a ruminant. Appl. Environ. Microbiol. 32(3), 433-444
87. A Huwig, S Freimund, O Kappeli and H Dutler (2001) Mycotoxin detoxification of animal feed by different adsorbents. Toxicol. Lett. 122(2), 179-188
88. Z Jesenska and I Sajbidorova (1991) T-2 toxin degradation by micromycetes. J. Hyg. Epidemiol. Microbiol. Immunol. 35(1), 41-49
89. F T Jones, M J Wineland, J T Parsons and W M Hagler Jr (1996) Degradation of aflatoxin by poultry litter. Poult. Sci. 75(1), 52-58
90. K V Jorgensen, D L Park, S M Rua and R L Price (1990) Reduction of mutagenic potentials in milk: Effects of ammonia treatment on aflatoxin-contaminated cottonseed. J. Food Protect. 53(9), 777-778
91. C Kadakal and S Nas (2003) Effect of heat treatment and evaporation on patulin and some other properties of apple juice. J. Sci. Food Agric. 83(9), 987-990
92. C Kadakal, N Sebahattin and E S Poyrazoglu (2002) Effect of commercial processing stages of apple juice on patulin, fumaric acid and hydroxymethylfurfural. J. Food Quality. 25(4), 359-368
93. H Kamimura (1986) Conversion of zearalenone to zearalenone glycoside by Rhizopus sp. Appl. Environ. Microbiol. 52(3), 515-519
94. P Karlovsky and A Wolf-Gerhard (1993) Screening of expression cDNA libraries for polysaccharide hydrolyzing enzymes. Meth. Mol. Cell Biol. 4(1), 40-45
95. P Karlovsky (1999) Biological detoxification of fungal toxins and its use in plant breeding, feed and food production. Nat. Toxins. 7(1), 1-23
96. D G Kennedy, S A Hewitt, J D G McEvoy, J W Currie, A Cannavan, W J Blanchflower and C T Elliot (1998) Zeranol is formed from Fusarium spp. toxins in cattle in vivo. Food Addit. Contam. 15(4), 393-400
97. K H Kiessling, H Patterson, K Sandholm and M Olsen (1984) Metabolism of aflatoxin, ochratoxin, zearalenone and three trichothecenes by intact rumen fluid, rumen protozoa and rumen bacteria. Appl. Environ. Microbiol. 47(5), 1070-1073
98. J-G K Kim, A E Yousef and S Dave (1999) Application of ozone for enhancing the microbiological safety and quality of foods: A review. J. Food Protect. 62(9), 1071-1087
99. M Kimura, I Kaneko, M Komiyama, A Takatsuki, H Koshino, K Yoneyama and I Yamaguchi (1998) Trichothecene 3-O-acetyltransferase protects both the producing organism and transformed yeast from related mycotoxins. Cloning and characterization of Tri101. J. Biol. Chem. 273(3), 1654-1661
100. M Kimura, Y Shingu, K Yoneyama and I Yamaguchi (1998) Features of Tri101, the trichothecene 3-O-acetyltransferase gene, related to the self-defense mechanism in. Fusarium graminearum, Biosci. Biotechnol. Biochem. 62(5), 1033-1036
101. L K Kirby, T S Nelson, J T Halley and J N Beasley (1987) Citrinin toxicity in young chicks. Poultry Sci. 66(6), 966-968
102. N Kitabatake, A B Trivedi and E Doi (1991) Thermal decomposition and detoxification of citrinin under various moisture conditions. J. Agric. Food Chem. 39(12), 2240-2244
103. P Krogh, B Hald, P Gjertsen and F Myken (1974) Fate of ochreatoxin A and citrinin during malting and brewing experiments. Appl. Microbiol. 28(1), 31-34
104. L F Kubena, R B Harvey, W E Huff, D E Corrier, T D Phillips and G E Rottinghaus (1990) Efficacy of a hydrated sodium calcium aluminosilicate to reduce the toxicity of aflatoxin and T-2 toxin. Poultry Sci. 69(7), 1078-1086
105. M E Kuilman, R F Mass, F M Woutersen-van Nijnantan and J Fink-Gremmels (2000) Inhibition of aflatoxin M1 production by bovine hepatocytes after intervention with oltipraz. Vet Q. 22(1), 30-35
106. J Lacey and N Magan (1991) Fungi in cereal grains: their occurrence and water and temperature relationships. J Chelkowski, (Eds) Cereal Grain, Mycotoxins, Fungi and Quality in Drying and Storage: Developments in Food Science. 26 Amsterdam: Elsevier 77-119
107. T E Lawlor, S R Haworth, E Zeiger, D L Park and L S Lee (1985) Mutagenic potential of ammonia- related aflatoxin reaction products in cottonseed meal. J. Am. Oil Chem. Soc. 62(7), 1136-1138
108. J F Lawrence, B Niedzwiadek and P M Scott (2000) Effect of temperature and solvent composition on extraction of fumonisins B-1 and B-2 from corn products. J. Am. Oil Anal. Chem. 83(3), 604-611
109. L S Lee, J B Stanely, A F Cucullu, W A Pons and L A Goldblatt (1974) Ammoniation of aflatoxin B1: isolation and identification of the major reaction product. J. Assoc. Off. Anal. Chem. 57(3), 626-631
110. S L Lee and A F Cucullu (1978) Conversion of aflatoxin B1 to aflatoxin D1 in ammoniated peanut and cottonseed meals. J. Agric. Food Chem. 26(4), 881-884
111. N L Leggott, G S Shephars, S Stockenstrom, E Stall and D J van Schatkwyk (2001) The reduction of patulin in apple juice by three different types of activated carbon. Food Addit. Contam. 18(9), 825-829
112. S L Lemke, P G Grant and T D Phillips (1998) Adsorption of zearalenone by organophilic montmorillonite clay. J. Agric. Food Chem. 46(9), 3789-3796
113. C Levi (1980) Mycotoxins in coffee. J. Assoc. Off. Anal. Chem. 63(6), 1282-1285
114. C P Levi, H L Trenk and H K Mohr (1974) Study of the occurrence of ochratoxin A in green coffee beans. J. Assoc. Off. Anal. Chem. 57(4), 866-870
115. E B Lillehoj, R D Stubblefield, G M Shannon and O L Shotwell (1971) Aflatoxin M1 removal from aqueous solution by Flavobacterium aurantiacum and resulting toxic effects. Mycopath. Mycol. Appl. 45(3), 259
116. J E Line and R E Brackett (1995) Role of toxin concentration and second carbon source in microbial transformation of aflatoxin B1 by. Flavobacterium aurantiacum, J Food Protect. 58(9), 1042-1044
117. D L Liu, D S Yao, Y Q Liang, T H Zhou, Y P Song, L Zhao and L Ma (2001) Production, purification, and characterization of an intracellular aflatoxin-detoxifizyme from Armillariella tabescens (E-20). Food Chem. Toxicol. 39(5), 461-466
118. R López-Garcia and L D Park (1988) Effectiveness of postharvest procedures in management of mycotoxin hazards. K K Sinha, D Bhatnagar, (Eds) Mycotoxins in Agriculture and Food Safety. New York: Marcel Dekker Inc. 407-433
119. Z Lu, W R Dantzer, E C Hopmans, V Prisk, J E Cunnik, P A Murphy and S Hendric (1977) Reaction with fructose detoxifies fumonisin B1 while stimulating liver-associated natural killer cell activity in rats. J. Agr. Food Chem. 45(1), 803-809
120. L Luter, W Wyslouzil and S C Kashyap (1982) The destruction of aflatoxin in peanuts by microwave roasting. Can. Inst. Food Sci. Technol. J. 15(3), 236-238
121. M Manabe and S Matsuura (1972) Studies on the fluorescent compounds in fermented foods. Part IV. Degradation of added aflatoxin during miso fermentation. J. Food Sci. Technol. 9(6), 275
122. R Mann and H J Rehm (1976) Degradation products from aflatoxin B1 by Corynebacterium rubrum, Aspergillus niger, Trichoderma viride and. Mucor ambiguous, Eur. J. Appl. Microbiol. 2 297-306
123. G E Mann, L P Codifer Jr and F G Dollear (1967) Effects of heat on aflatoxin in oilseed meals. J. Agric. Food Chem. 15(6), 1090-1092
124. G E Mann, L P Codifer, H K Gardner, S P Koltun and F G Dollear (1970) Chemical inactivation of aflatoxins in peanut and cottonseed meals. J. Am. Oil Chem. Soc. 47(5), 173-176
125. K S McKenzie, A B Sarr, K Mayura, R H Bailey, D R Miller, T D Rogers, W P Norred, K A Voss, R D Plattner, L F Kubena and T D Phillips (1997) Oxidative degradation and detoxification of mycotoxins using a novel source of ozone. Food Chem. Toxicol. 35(8), 807-820
126. K S McKenzie, L F Fubena, A J Denvir, T D Rogers, G D Hitchens, R H Bailey, R B Harvey, S A Buckly and T D Phillips (1998) Aflatoxicosis in turkey poults is prevented by treatment of naturally contaminated corn with ozone generated by electrolysis. Poultry Sci. 77(8), 1094-1102
127. S E Megalla and M A Mohran (1984) Fate of aflatoxin B1 in fermented dairy products. Mycopathologia 88(1), 27-29
128. M Megharaj, I Garthwaite and J H Thieele (1997) Total biodegradation of the oestrogenic mycotoxin zearalenone by bacterial culture. Lett. Appl. Microbiol. 24(5), 329-333
129. D Mertz, D Lee, M Zuber and E Lillehoj (1980) Uptake and metabolism of aflatoxin by. Zea mays, J. Agric. Food Chem. 28(5), 963-966
130. J D Miller (1995) Fungi and mycotoxins in grain: implications for stored product research. J. Stored Prod. Res. 31(1), 1-6
131. J D Miller and J C Young (1985) Deoxynivalenol in an experimental Fusarium graminearum infection of wheat. Can. J. Plant Pathol. 7(2), 132-134
132. J D Miller, J C Young and H L Trenholm (1983) Fusarium toxins in field corn. I. Time course of fungal growth and production of deoxynivalenol and other mycotoxins. Can. J. Bot. 61(12), 3080-3087
133. C J Mirocha, S V Pathre and T S Robson (1981) Comparative metabolism of zearalenone and transmission into bovine milk. Food Cosmet. Toxicol. 19(1), 25-30
134. K E Moerck, P McElfresh, A Wohlman and B W Hilton (1980) Aflatoxin destruction in corn using sodium bisulfite, sodium hydroxide, and aqueous ammonia. J. Food Protect. 43(7), 571-574
135. C Moreau (1979) Moulds, Toxins and Food Chichester: John Wiley & Sons
136. M O Moss (1998) Recent studies of mycotoxins. J. Appl. Microbiol. 84 62S-76S
137. M O Moss and M T Long (2002) Fate of patulin in the presence of the yeast. Saccharomyces cerevisiae, Food Addit. Contam. 19(4), 387-399
138. P A Murphy, S Hendrich, E C Hopmans, C C Hauck, Z Lu, G Buseman and G Munkvold (1996) Effect of processing on fumonisin content of corn. L S Jackson, J W Devries, L B Bullerman, (Eds) Fumonisins in Food New York: Plenum Press 323-334
139. K R Natarajan, K C Rhee, C M Cater and K F Mattil (1975) Destruction of aflatoxins in peanut protein isolates by sodium hypochlorite. J. Am. Oil Chem. Soc. 52(5), 160-163
140. G E Neal, D J Judah, P Carthew, A Verma, I Latour, L Weir, R D Coker, M J Nagler and L A P Hoogenboom (2001) Differences detected in vivo between samples of aflatoxin-contaminated peanut meal, following decontamination by two ammonia-based processes. Food Addit. Contam. 18(2), 137-149
141. E V Niles (April 1978) Growth rate and aflatoxin production of Aspergillus flavus in wheat sterilized by gamma irradiation, ethylene oxide fumigation and autoclaving. Trans. Br. Mycol. Soc. 70 239-247
142. W K Nip, F C Chang, F S Chu and N Prentice (1975) Fate of ochratoxin A in brewing. Appl. Microbiol. 30(6), 1048-1049
143. W P Norred, K A Voss, C W Bacon and R T Riley (1991) Effectiveness of ammonia treatment in detoxification of fumonisin-contaminated corn. Fd. Chem. Toxicol. 29(12), 815-819
144. M J R Nout (1989) Effect of Rhizopus and Neurospora spp. on growth of Aspergillus flavus and A. parasiticus and accumulation of aflatoxin B1 in groundnut. Mycol. Res. 93 518-523
145. J T Oatley, M D Rarick, G E Ji and J E Linz (2000) Binding of aflatoxin B1 to. Bifidobacteria in vitro, J. Food Protect. 63(8), 1133-1136
146. K O'Neill, A P Damoglu and M F Patterson (1993) The stability of deoxynivalenol and 3-acetyl deoxynivalenol to gamma irradiation. Food Addit. Contam. 10(2), 209-215
147. D Park (1993) Perspective on mycotoxin decontamination procedures. Food Addit. Contam. 10(1), 49-60
148. D L Park, L S Lee, R L Price and A E Pohland (1988) Review of the decontamination of aflatoxins by ammoniation: current status and regulation. J. Assoc. Off. Anal. Chem. 71(4), 685-703
149. D L Park, R Lopez-Garcia, S Trujillo-Preciado and R I Price (1996) Reduction of risks associated with fumonisin contamination in corn. L S Jackson, J W DeVries, L B Bullerman, (Eds) Fumonisins in Food New York: Plenum Press 335-344
150. D L Park, S M Rua, C J Mirocha, E M A Abd-Alla and C Y Weng (1992) Mutagenic potentials of fumonisin contaminated corn following ammonia decontamination procedures. Mycopathologia 117(1-2), 105-108
151. W A Parker and D Melnick (1966) Absence of aflatoxins from refined vegetable oil. J. Am. Oil Chem. Soc. 43(11), 635-638
152. N Paster, R Barkai-Golan and R Padova (1985) Effect of gamma radiation on ochratoxin production by the fungus. Aspergillus ochraceus, J. Sci. Food Agric. 36(6), 445-449
153. U D Patel, P Govindarajan and P J Dave (1989) Inactivation of aflatoxin B1 using the synergistic effect of hydrogen peroxide and gamma radiation. Appl. Environ. Microbiol. 55(2), 465-467
154. T D Phillips, L F Kubena, R B Harvey, D R Taylor and N D Heidelbaugh (1988) Hydrated sodium calcium aluminosilicate: a high affinity sorbent for aflatoxin. Poult. Sci. 67(2), 243-247
155. T D Phillips, B A Clement and D L Park (1994) Approaches to reduction of aflatoxins in foods and feeds. D L Eaton, J D Groopman, (Eds) The Toxicology of Aflatoxins - Human Health, Veterinary and Agricultural Significance San Diego, CA: Academic Press 383-406
156. M Pierides, H El-Nezami, K Peltonen, S Salminen and J Ahokas (2000) Ability of dairy strains of lactic acid bacteria to bind aflatoxin M1 in a food model. J. Food Protect. 63(5), 645-650
157. H R Pluyer, E M Ahmed and C I Wei (1987) Destruction of aflatoxin on peanuts by oven-roasting and microwave-roasting. J. Food Protect. 50(6), 504-508
158. B Poppenberger, F Berthiller, D Lucyshyn, T Sieberer, R Schuhmacher, R Krska, K Kuchler, J Glossl, C Luschnig and G Adam (2003) Detoxification of the Fusarium mycotoxin deoxynivalenol by a UDP-glucosyltransferase from. Arabidopsis thaliana, J. Biol. Chem. 278(48), 47905-47914
159. R L Price and K V Jorgensen (1985) Effect of processing on aflatoxin levels and on mutagenic potential of tortillas made from naturally contaminated corn. J. Food Sci. 50(2), 347-349
160. E Priyadarshini and P G Tulpule (1976) Aflatoxin production on irradiated foods. Food Cosmet. Toxicol. 14(4), 293-295
161. A D Prudente Jr and J M King (2002) Efficacy and safety evaluation of ozonation to degrade aflatoxin in corn. J. Food Sci. 67(8), 2866-2872
162. R Pujol, M Torres, V Sanchis and R Canela (1999) Fate of fumonisin B1 in corn kernel steeping water containing SO2. J. Agr. Food Chem. 47(1), 276-278
163. A-J Ramos and E Hernandez (1996) In vitro aflatoxin absorption by means of a montmorillonited silicate: a study of adsorption isotherms. Anim. Feed Sci. Technol. 62(2-4), 263-269
164. A-J Ramos, J Fink-Gremmels and E Hernandez (1996) Prevention of toxic effects of mycotoxins by means of nonnutritive adsorbent compounds. J. Food Protect. 5(6), 631-641
165. E T Rayner and F G Dollear (1968) Removal of aflatoxins from oilseed meals by extraction with aqueous isopropanol. J. Am. Oil Chem. Soc. 45(9), 622-624
166. B N Reddy (1987) Effect of gamma-radiation on aflatoxin concentration. Natl. Acad. Sci. Lett. (India) 10(6), 203-204
167. R G Rotter, A A Frohlic and R R Marquardt (1989) Influence of dietary charcoal on ochratoxin A toxicity in leghorn chicks. Can. J. Vet. Res. 53(4), 449-453
168. M Ruhland, G Engelhardt and P R Wallnofer (1994) Transformation of the mycotoxin ochratoxin A in wheat and maize cell suspension cultures. Naturwissenschaften 81(10), 453-454
169. M Ruhland, G Engelhardt, W Schafer and P R Wallnofer (1996) Transformation of the mycotoxin ochratoxin in plants. 1. Isolation and identification of metabolites formed in cell suspension cultures of wheat and maize. Nat. Toxins. 4(6), 254-260
170. M Ruhland, G Engelhardt and P R Wallnofer (1996) Transformation of the mycotoxin ochratoxin in plants. 2. Time course and rates of the degradation and metabolite production in cell-suspension cultures of different crop plants. Mycopathologia 134(2), 97-102
171. D C Sands, J L McIntyre and G S Walton (1976) Use of activated charcoal for the removal of patulin from cider. Appl. Environ. Microbiol. 32(3), 388-391
172. E M Schmelz, M A Dombrink-Kurtzman, P C Roberts, Y Kozutsumi, T Kawasaki and A H Merill Jr (1998) Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. Toxicol. Appl. Pharmacol. 148(2), 252-260
173. P B Schwarz, H H Casper and S Beattie (1995) Fate and development of naturally occurring Fusarium mycotoxins during malting and brewing. J. Am. Soc. Brew. Chem. 53(3), 121-127
174. S Schwenk, B Altmayer and K W Eichhorn (1989) Untersuchungen zur Bedeutung toxischer Stoffwechselprodukte des Pilzes Trichothecum roseum Link et Fr.fuer den Weinbau, Z. Lebensm. Unters Forsch. 188(6), 527-530
175. P M Scott (1984) Effect of food processing on mycotoxins. J. Food Protect. 47(6), 489-499
176. P M Scott (1991) Possibilities of reduction or elimination of mycotoxins present in cereal grains. J Chelkowski, (Eds) Cereal Grain; Mycotoxins, Fungi and Quality in Drying and Storage. Amsterdam: Elsevier 529-572
177. P M Scott (1998) Industrial and farm detoxification processes for mycotoxins. Revue Méd. Vét. 149(6), 543-548
178. P M Scott, S R Kanhere, P Y Lau, J E Dexter and R Greenhalg (1983) Effects of experimental flour milling and breadbaking on retention of deoxynivalenol (vomitoxin) in hard red spring wheat. Cereal Chem. 60(6), 421-424
179. P M Scott, S R Kanhere, E F Daley and J M Farber (1992) Fermentation of wort containing deoxynivalenol and zearalenone. Mycotoxin Res. 8(22), 58-66
180. P M Scott, S R Kanhere, G A Lawrence, E F Daley and J M Farber (1995) Fermentation of wort containing added ochratoxin A and fumonisin B1 and B2. Food Addit. Contam. 12(1), 31-40
181. L M Seitz, W D Eustace, H E Mohr, M D Shogren and W T Yamazaki (1986) Cleaning, milling and baking tests with hard red winter-wheat containing deoxynivalenol. Cereal Chem. 63(2), 146-150
182. A C Sen, C I Wei, S Y Fernando, J Toth, E M Ahmed and G E Dunaif (1988) Reduction in mutagenicity and toxicity of aflatoxin B1 by chlorine gas treatment. Food Chem. Toxicol. 26(9), 745-752
183. T Shantha (1999) Fungal degradation of aflatoxin B1. Nat. Toxins. 7(5), 175-178
184. T Shantha and V S Sreenivasa Murthy (1975) Detoxification of groundnut oil. J. Food Sci. Technol. 12(1), 20-24
185. A Sharma (1998) Mycotoxins: risk evaluation and management in radiation-processed foods. K K Sinha, D Bhatnagar, (Eds) Mycotoxins in Agriculture and Food Safety. New York: Marcel Dekker Inc. 435-457
186. P H Shetty and R V Bhat (1999) Physical method for segregation of fumonisin-contaminated maize. Food Chem. 66(3), 371-374
187. C N Shih and E H Marth (1975) Aflatoxin can be degraded by the mycelium of. Aspergillus parasiticus, Z. Lebensm. Unters. Forsch. 158(6), 361-362
188. J Shima, S Takase, Y Takahashi, Y Iwai, H Fujimoto, M Yamazaki and K Ochi (1997) Novel detoxification of the trichothecene mycotoxin deoxynivalenol by a soil bacterium isolated by enrichment culture. Appl. Environ. Microbiol. 63(10), 3825-3830
189. K K Sinha (1998) Detoxification of mycotoxins and food safety. K K Sinha, D Bhatnagar, (Eds) Mycotoxins in Agriculture and Food Safety. New York: Marcel Dekker Inc. 381-405
190. R N Sinha and W E Muir (1973) Grain Storage. Part of a System. Westport, CT: Avi Publ. Inc
191. T K Smith (1980) Influence of dietary fiber, protein and zeolite on zearalenone toxicosis in rats and swine. J. Anim. Sci. 50(2), 278-285
192. T K Smith (1984) Spent canola oil bleaching clays: Potential for treatment of T-2 toxicosis in rats and short-term inclusion in diets for immature swine. Can. J. Anim. Sci. 64(3), 725-732
193. K M Soliman, A A El-Faramawy, S M Zakaria and S H Mekkawy (2001) Monitoring the preventive effect of hydrogen peroxide and γ-radiation on aflatoxicosis in growing rabbits and the effect of cooking on aflatoxin residues. J. Agric. Food Chem. 49(7), 3291-3295
194. V Sreenivasamurthy, H A B Parpia, S Srikanta and A S Murti (1967) Detoxification of aflatoxin in peanut meal by hydrogen peroxide. J. Assoc. Off. Anal. Chem. 50(2), 350-354
195. J A Steele, C J Mirocha and S V Pathre (1977) Metabolism of zearalenone by. Fusarium roseum, J. Toxicol. Environ. Health. 3(1-2), 35-42
196. E E Stinson, S F Osman, C N Huhtanen and D D Bills (1978) Disappearance of patulin during alchoholic fermentation of apple juice. Appl. Environ. Microbiol. 36(4), 620-622
197. E E Stinson, S F Osman and D D Bills (1979) Water-soluble products from patulin during alchoholic fermentation of apple juice. J. Food Sci. 44(3), 788-796
198. I Studer-Rohr, D R Dietrich, J Schlatter and C Schlatter (1995) The occurrence of ochratoxin A in coffee. Food Chem. Toxicol. 33(5), 341-355
199. S P Swanson, W M Hagler and H D Rood (1984) Destruction of deoxynivalenol (vomitoxin) with sodium bisulfite (abstr.). Ann. Meet. Am. Soc. Microbiol. 84 192
200. S P Swanson, C Helaszek, W B Buck, H D Rood Jr and W M Haschek (1988) The role of intestinal microflora in the metabolism of trichothecene mycotoxins. Food Chem. Toxicol. 26(10), 823-829
201. E W Sydenham, S Stockenstrom, P G Thiel, G S Shephard, K K Koch and W F O Marasas (1995) Potential of alkaline hydrolysis for the removal of fumonisin from contaminated corn. J. Agr. Food Chem. 43(5), 1198-1201
202. T Tanaka, A Hasegawa, S Yamamoto, Y Matsuki and Y Ueno (1986) Residues of Fusarium mycotoxins nivalenol, deoxynivalenol and zearalenone, in wheat and processed food after milling and baking. J. Food Hyg. Soc. Jpn. 27(6), 653-655
203. P Temcharoen and W G Thilly (1982) Removal of aflatoxin B1 toxicity but not mutagenicity by 1 megarad gamma radiation of peanut meal. J. Food Saf. 4(4), 199-205
204. Thimm N, Wei G, Ottner F, Schwaighofer B and Binder E M (2000), Adsorption of mycotoxins - characterisation of the specificity of different clays, in Proceedings of the 10th International IUPAC Symposium on Mycotoxins and Phycotoxins, Guaruja, Brasil, 21-25 May, p.82 (abstract)
205. C Tozzi, L Anfossi, C Baggini, C Giovannoli and G Giraudi (2003) A combinatorial approach to obtain affinity media with binding properties towards the aflatoxins. Anal. Bioanal. Chem. 375(8), 994-999
206. W T Trager and L Stoloff (1967) Possible reactions for aflatoxin detoxification. J. Agric. Food Chem. 15(4), 679-681
207. H L Trenk, M E Butz and F S Chu (1971) Production of ochratoxin in different cereal products by. Aspergillus ochraceus, Appl. Microbiol. 21(6), 1032-1035
208. A B Trivedi, E Doi and N Kitabatake (1992) Detoxification of ochratoxin A on heating under acidic and alkaline conditions. Biosci. Biotechnol. Biochem. 56(5), 741-745
209. A Turbic, J T Ahokas and C A Haskard (2002) Selective in vitro binding of dietary mutagens, individually or in combination, by lactic acid bacteria. Food Addit. Contam. 19(2), 144-152
210. M Ulloa-Sosa and H W Shroeder (1969) Note on aflatoxin decontamination in the process of making tortillas from corn. Cereal Chem. 46(4), 397-400
211. G H van der Stegen, P J Essens and J van der Lijn (2001) Effect of roasting conditions on reduction of ochratoxin A in coffee. J. Agric. Food Chem. 49(10), 4713-4715
212. P J van Dyck, P Tobback, M Feys and H van de Voorde (1982) Sensitivity of aflatoxin B1 to ionizing radiation. Appl. Environ. Microbiol. 43(6), 1317-1319
213. J Varga, K Rigo and J Teren (2000) Degradation of ochratoxin A by Aspergillus species. Int. J. Food Microbiol. 59(1-2), 1-7
214. R Viani (2002) Effect of processing on ochratoxin A (OTA) content of coffee. Adv. Exp. Med. Biol. 504 189-193
215. A Visconti, M Solfrizzo, M B Doko, A Boenke and M Pascale (1996) Stability of fumonisins at different storage periods and temperatures in γ-irradiated maize. Food Addit. Contam. 13(8), 929-938
216. Völkl A, Woerfel G, Haeussermann T, Vogler B, Klaiber I and Karlovsky P (1997), Biotransformation von Myckotoxinen von Fusarium spp., in Proceedings of the 19th Mykotoxin-Workshop, Munich, Germany, 2-4 June, 45-9
217. K Westlake, R I Mackie and M F Dutton (1989) In vitro metabolism of mycotoxins by bacterial, protozoal and ovine ruminal fluid preparations. Anim. Feed Sci. Technol. 25(1-2), 169-178
218. N R Worrell, A K Mallett, C W Cook, N C Baldwin and M J Shepherd (1989) The role of gut micro-organisms in the metabolism of deoxynivalenol administered to rats. Xenobiotica 19(1), 25-32
219. T Yoshizawa and N Morooka (1975) Biological modification of trichothecene mycotoxins: acetylation and deacetylation of deoxynivalenols by Fusarium spp. Appl. Microbiol. 29(1), 54-58
220. T Yoshizawa, C Onomoto and N Morooka (1980) Microbial acetyl conjugation of T-2 toxin and its derivatives. Appl. Environ. Microbiol. 39(5), 962-966
221. J C Young (1986) Reduction of deoxynivalenol in contaminated corn by chemical and physical treatment. J. Agric. Food Chem. 34(3), 465-467
222. J C Young, R G Fulcher, J H Hayhoe, P M Scott and J E Dexter (1984) Effect of milling and baking on deoxynivalenol (vomitoxin) content of eastern Canadian wheats. J. Agr. Food Chem. 32(3), 659-664
223. J C Young, L M Subryan, D Potts, M E McLaren and F H Gobran (1986) Reduction in levels of deoxynivalenol in contaminated wheat by chemical and physical treatment. J. Agric. Food Chem. 34(3), 461-465
224. J C Young, H L Trenholm, D W Friend and D B Prelusky (1987) Detoxification of deoxynivalenol with sodium bisulfite and evaluation of the effects when pure mycotoxin or contaminated corn was treated and given to pigs. J. Agr. Food Chem. 35(2), 259-261
225. H Zegota, A Zegota and S Bachman (1988) Effect of irradiation on the patulin content and chemical composition of apple juice concentrate. Z. Lebensm. Unters. Forsch. 187(3), 235-238
226. X B Zhang and Y Ohta (1993) Microorganisms in the gastrointestinal tract of the rat prevent absorption of the mutagen-carcinogen 3-amino-1, 4-dimethyl-5H-pyrido(4, 3-b)indole. Can. J. Microbiol. 39(9), 841-845