메뉴 건너뛰기




Volumn 94, Issue 11, 2004, Pages 1515-1522

PPARγ agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: Role of diacylglycerol kinase

Author keywords

Diabetic complications; Diacylglycerol kinase; PPAR ; Protein kinase C; Vascular inflammation

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; 3 [2 [4 (4,4' DIFLUOROBENZHYDRYLIDENE)PIPERIDINO]ETHYL] 2,3 DIHYDRO 2 THIOXO 4(1H) QUINAZOLINONE; CIGLITAZONE; COMPLEMENTARY DNA; DIACYLGLYCEROL; GLUCOSE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; TROGLITAZONE; VASCULOTROPIN; 15 DEOXYPROSTAGLANDIN J2; 15-DEOXYPROSTAGLANDIN J2; CELL ADHESION MOLECULE; CHROMAN DERIVATIVE; DIACYLGLYCEROL KINASE; DRUG DERIVATIVE; HYBRID PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN D2; PROTEIN KINASE C BETA;

EID: 2942670612     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000130527.92537.06     Document Type: Article
Times cited : (97)

References (38)
  • 1
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis: An inflammatory disease
    • Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med. 1999; 340:115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 2
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature. 2002;420:868-874.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 3
    • 0035851187 scopus 로고    scopus 로고
    • PPARgamma: A nuclear regulator of metabolism, differentiation, and cell growth
    • Rosen ED, Spiegelman BM. PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem. 2001;276: 37731-37734.
    • (2001) J Biol Chem , vol.276 , pp. 37731-37734
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 4
    • 0034878539 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs) and their role in the vessel wall: Possible mediators of cardiovascular risk?
    • Marx N, Libby P, Plutzky J. Peroxisome proliferator-activated receptors (PPARs) and their role in the vessel wall: possible mediators of cardiovascular risk? J Cardiovasc Risk. 2001;8:203-210.
    • (2001) J Cardiovasc Risk , vol.8 , pp. 203-210
    • Marx, N.1    Libby, P.2    Plutzky, J.3
  • 6
    • 0031724132 scopus 로고    scopus 로고
    • Potent inhibitory effect of troglitazone on carotid arterial wall thickness in type 2 diabetes
    • Minamikawa J, Tanaka S, Yamauchi M, Inoue D, Koshiyama H. Potent inhibitory effect of troglitazone on carotid arterial wall thickness in type 2 diabetes. J Clin Endocrinol Metab. 1998;83:1818-1820.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1818-1820
    • Minamikawa, J.1    Tanaka, S.2    Yamauchi, M.3    Inoue, D.4    Koshiyama, H.5
  • 8
    • 0029060391 scopus 로고
    • Protein kinase C and lipid signaling for sustained cellular responses
    • Nishizuka Y. Protein kinase C and lipid signaling for sustained cellular responses. FASEB J. 1995;9:484-496.
    • (1995) FASEB J , vol.9 , pp. 484-496
    • Nishizuka, Y.1
  • 9
    • 0029975352 scopus 로고    scopus 로고
    • Biochemical and molecular mechanisms in the development of diabetic vascular complications
    • King GL, Kunisaki M, Nishio Y, Inoguchi T, Shiba T, Xia P. Biochemical and molecular mechanisms in the development of diabetic vascular complications. Diabetes. 1996;45 Suppl 3:S105-108.
    • (1996) Diabetes , vol.45 , Issue.SUPPL. 3
    • King, G.L.1    Kunisaki, M.2    Nishio, Y.3    Inoguchi, T.4    Shiba, T.5    Xia, P.6
  • 10
    • 0027437753 scopus 로고
    • Diacylglycerol/protein kinase C signalling: A mechanism for insulin resistance?
    • Shmueli E, Alberti KG, Record CO. Diacylglycerol/protein kinase C signalling: a mechanism for insulin resistance? J Intern Med. 1993;234: 397-400.
    • (1993) J Intern Med , vol.234 , pp. 397-400
    • Shmueli, E.1    Alberti, K.G.2    Record, C.O.3
  • 12
    • 0033597338 scopus 로고    scopus 로고
    • Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions
    • Topham MK, Prescott SM. Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions. J Biol Chem. 1999;274: 11447-11450.
    • (1999) J Biol Chem , vol.274 , pp. 11447-11450
    • Topham, M.K.1    Prescott, S.M.2
  • 14
    • 0029087910 scopus 로고
    • Identification of the mechanism for the inhibition of Na+, K(+)-adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2
    • Xia P, Kramer RM, King GL. Identification of the mechanism for the inhibition of Na+, K(+)-adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2. J Clin Invest. 1995;96:733-740.
    • (1995) J Clin Invest , vol.96 , pp. 733-740
    • Xia, P.1    Kramer, R.M.2    King, G.L.3
  • 16
    • 0029998639 scopus 로고    scopus 로고
    • Molecular cloning of a novel human diacylglycerol kinase highly selective for arachidonate-containing substrates
    • Tang W, Bunting M, Zimmerman GA, McIntyre TM, Prescott SM. Molecular cloning of a novel human diacylglycerol kinase highly selective for arachidonate-containing substrates. J Biol Chem. 1996;271: 10237-10241.
    • (1996) J Biol Chem , vol.271 , pp. 10237-10241
    • Tang, W.1    Bunting, M.2    Zimmerman, G.A.3    McIntyre, T.M.4    Prescott, S.M.5
  • 17
    • 0027981889 scopus 로고
    • Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia
    • Xia P, Inoguchi T, Kern TS, Engerman RL, Oates PJ, King GL. Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia. Diabetes. 1994;43:1122-1129.
    • (1994) Diabetes , vol.43 , pp. 1122-1129
    • Xia, P.1    Inoguchi, T.2    Kern, T.S.3    Engerman, R.L.4    Oates, P.J.5    King, G.L.6
  • 19
    • 0033954192 scopus 로고    scopus 로고
    • Selectivity of the diacylglycerol kinase inhibitor 3-[2-(4-[bis-(4- fluorophenyl)methylene]-1-piperidinyl)ethyl]-2, 3-dihydro-2-thioxo-4(1H) quinazolinone (R59949) among diacylglycerol kinase subtypes
    • Jiang Y, Sakane F, Kanoh H, Walsh JP. Selectivity of the diacylglycerol kinase inhibitor 3-[2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl)ethyl]-2, 3-dihydro-2-thioxo-4(1H)quinazolinone (R59949) among diacylglycerol kinase subtypes. Biochem Pharmacol. 2000;59:763-772.
    • (2000) Biochem Pharmacol , vol.59 , pp. 763-772
    • Jiang, Y.1    Sakane, F.2    Kanoh, H.3    Walsh, J.P.4
  • 20
    • 0027977387 scopus 로고
    • Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissues
    • Inoguchi T, Xia P, Kunisaki M, Higashi S, Feener EP, King GL. Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissues. Am J Physiol. 1994;267:E369-E379.
    • (1994) Am J Physiol , vol.267
    • Inoguchi, T.1    Xia, P.2    Kunisaki, M.3    Higashi, S.4    Feener, E.P.5    King, G.L.6
  • 21
    • 0026489335 scopus 로고
    • Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: Differential reversibility to glycemic control by islet cell transplantation
    • Inoguchi T, Battan R, Handler E, Sportsman JR, Heath W, King GL. Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation. Proc Natl Acad Sci U S A. 1992;89:11059-11063.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 11059-11063
    • Inoguchi, T.1    Battan, R.2    Handler, E.3    Sportsman, J.R.4    Heath, W.5    King, G.L.6
  • 23
    • 0025896795 scopus 로고
    • Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis
    • Cybulsky MI, Gimbrone MA Jr. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science. 1991;251: 788-791.
    • (1991) Science , vol.251 , pp. 788-791
    • Cybulsky, M.I.1    Gimbrone Jr., M.A.2
  • 24
    • 0030065688 scopus 로고    scopus 로고
    • Neovascular expression of E-selectin, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 in human atherosclerosis and their relation to intimal leukocyte content
    • O'Brien KD, McDonald TO, Chait A, Allen MD, Alpers CE. Neovascular expression of E-selectin, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 in human atherosclerosis and their relation to intimal leukocyte content. Circulation. 1996;93:672-682.
    • (1996) Circulation , vol.93 , pp. 672-682
    • O'Brien, K.D.1    McDonald, T.O.2    Chait, A.3    Allen, M.D.4    Alpers, C.E.5
  • 25
    • 0032032347 scopus 로고    scopus 로고
    • Native low density lipoprotein-induced calcium transients trigger VCAM-1 and E-selectin expression in cultured human vascular endothelial cells
    • Allen S, Khan S, Al Mohanna F, Batten P, Yacoub M. Native low density lipoprotein-induced calcium transients trigger VCAM-1 and E-selectin expression in cultured human vascular endothelial cells. J Clin Invest. 1998;101:1064-1075.
    • (1998) J Clin Invest , vol.101 , pp. 1064-1075
    • Allen, S.1    Khan, S.2    Al Mohanna, F.3    Batten, P.4    Yacoub, M.5
  • 26
    • 0032723117 scopus 로고    scopus 로고
    • High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL
    • Xia P, Vadas MA, Rye KA, Barter PJ, Gamble JR. High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL. J Biol Chem. 1999;274:33143- 33147.
    • (1999) J Biol Chem , vol.274 , pp. 33143-33147
    • Xia, P.1    Vadas, M.A.2    Rye, K.A.3    Barter, P.J.4    Gamble, J.R.5
  • 28
    • 0029088742 scopus 로고
    • Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes
    • Schmidt AM, Hori O, Chen JX, Li JF, Crandall J, Zhang J, Cao R, Yan SD, Brett J, Stern D. Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes. J Clin Invest. 1995;96:1395-1403.
    • (1995) J Clin Invest , vol.96 , pp. 1395-1403
    • Schmidt, A.M.1    Hori, O.2    Chen, J.X.3    Li, J.F.4    Crandall, J.5    Zhang, J.6    Cao, R.7    Yan, S.D.8    Brett, J.9    Stern, D.10
  • 29
    • 0034711678 scopus 로고    scopus 로고
    • Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators
    • Pasceri V, Wu HD, Willerson JT, Yeh ET. Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators. Circulation. 2000;101:235-238.
    • (2000) Circulation , vol.101 , pp. 235-238
    • Pasceri, V.1    Wu, H.D.2    Willerson, J.T.3    Yeh, E.T.4
  • 30
    • 0032847680 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction
    • Jackson SM, Parhami F, Xi XP, Berliner JA, Hsueh WA, Law RE, Demer LL. Peroxisome proliferator-activated receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction. Arterioscler Thromb Vasc Biol. 1999;19:2094-2104.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2094-2104
    • Jackson, S.M.1    Parhami, F.2    Xi, X.P.3    Berliner, J.A.4    Hsueh, W.A.5    Law, R.E.6    Demer, L.L.7
  • 31
    • 0037072826 scopus 로고    scopus 로고
    • Constitutive activation of peroxisome proliferator-activated receptor-gamma suppresses pro-inflammatory adhesion molecules in human vascular endothelial cells
    • Wang N, Verna L, Chen NG, Chen J, Li H, Forman BM, Stemerman MB. Constitutive activation of peroxisome proliferator-activated receptor-gamma suppresses pro-inflammatory adhesion molecules in human vascular endothelial cells. J Biol Chem. 2002;277:34176-34181.
    • (2002) J Biol Chem , vol.277 , pp. 34176-34181
    • Wang, N.1    Verna, L.2    Chen, N.G.3    Chen, J.4    Li, H.5    Forman, B.M.6    Stemerman, M.B.7
  • 32
    • 0035795411 scopus 로고    scopus 로고
    • Role of diacylglycerol kinase alpha in the attenuation of receptor signaling
    • Sanjuan MA, Jones DR, Izquierdo M, Merida I. Role of diacylglycerol kinase alpha in the attenuation of receptor signaling. J Cell Biol. 2001; 153:207-220.
    • (2001) J Cell Biol , vol.153 , pp. 207-220
    • Sanjuan, M.A.1    Jones, D.R.2    Izquierdo, M.3    Merida, I.4
  • 33
    • 0032849088 scopus 로고    scopus 로고
    • New insights into the regulation of protein kinase C and novel phorbol ester receptors
    • Ron D, Kazanietz MG. New insights into the regulation of protein kinase C and novel phorbol ester receptors. FASEB J. 1999;13:1658-1676.
    • (1999) FASEB J , vol.13 , pp. 1658-1676
    • Ron, D.1    Kazanietz, M.G.2
  • 34
    • 0033749209 scopus 로고    scopus 로고
    • Properties and functions of diacylglycerol kinases
    • van Blitterswijk WJ, Houssa B. Properties and functions of diacylglycerol kinases. Cell Signal. 2000;12:595-605.
    • (2000) Cell Signal , vol.12 , pp. 595-605
    • Van Blitterswijk, W.J.1    Houssa, B.2
  • 35
    • 0034595651 scopus 로고    scopus 로고
    • Thiazolidinedione treatment enhances insulin effects on protein kinase C-zeta/lambda activation and glucose transport in adipocytes of nondiabetic and Goto-Kakizaki type II diabetic rats
    • Kanoh Y, Bandyopadhyay G, Sajan MP, Standaert ML, Farese RV. Thiazolidinedione treatment enhances insulin effects on protein kinase C-zeta/lambda activation and glucose transport in adipocytes of nondiabetic and Goto-Kakizaki type II diabetic rats. J Biol Chem. 2000;275: 16690-16696.
    • (2000) J Biol Chem , vol.275 , pp. 16690-16696
    • Kanoh, Y.1    Bandyopadhyay, G.2    Sajan, M.P.3    Standaert, M.L.4    Farese, R.V.5
  • 36
    • 0035861760 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands inhibit mitogenic induction of p21(Cip1) by modulating the protein kinase Cdelta pathway in vascular smooth muscle cells
    • Wakino S, Kintscher U, Liu Z, Kim S, Yin F, Ohba M, Kuroki T, Schonthal AH, Hsueh WA, Law RE. Peroxisome proliferator-activated receptor gamma ligands inhibit mitogenic induction of p21(Cip1) by modulating the protein kinase Cdelta pathway in vascular smooth muscle cells. J Biol Chem. 2001;276:47650-47657.
    • (2001) J Biol Chem , vol.276 , pp. 47650-47657
    • Wakino, S.1    Kintscher, U.2    Liu, Z.3    Kim, S.4    Yin, F.5    Ohba, M.6    Kuroki, T.7    Schonthal, A.H.8    Hsueh, W.A.9    Law, R.E.10
  • 38
    • 0037031979 scopus 로고    scopus 로고
    • Vascular inflammation is negatively autoregulated by interaction between CCAAT/enhancer-binding protein-delta and peroxisome proliferator-activated receptor-gamma
    • Takata Y, Kitami Y, Yang ZH, Nakamura M, Okura T, Hiwada K. Vascular inflammation is negatively autoregulated by interaction between CCAAT/enhancer-binding protein-delta and peroxisome proliferator-activated receptor-gamma. Circ Res. 2002;91:427-433.
    • (2002) Circ Res , vol.91 , pp. 427-433
    • Takata, Y.1    Kitami, Y.2    Yang, Z.H.3    Nakamura, M.4    Okura, T.5    Hiwada, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.