The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth

Nature

Volumn 390, Issue 6655, 1997, Pages 78-81

  Nguyen, MyTrang ^a   Camenisch, Todd ^a   Snouwaert, John N ^a   Hicks, Elizabeth ^a   Coffman, Thomas M ^b   Anderson, Page A W ^c   Malouf, Nadia N ^a   Koller, Beverly H ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; ELASTIN; INDOMETACIN; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2 RECEPTOR, EP4 SUBTYPE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; BIRTH; CARDIOVASCULAR SYSTEM; CONTROLLED STUDY; DUCTUS ARTERIOSUS OBLITERATION; FEMALE; FETUS; IN SITU HYBRIDIZATION; LUNG CIRCULATION; MALE; MOUSE; NEWBORN; NONHUMAN; PATENT DUCTUS ARTERIOSUS; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; DBA MOUSE; DRUG EFFECT; DUCTUS ARTERIOSUS; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTATION; PATHOLOGY; PHYSIOLOGY; PREGNANCY;

ANIMALS; ANIMALS, NEWBORN; DINOPROSTONE; DUCTUS ARTERIOSUS; DUCTUS ARTERIOSUS, PATENT; FEMALE; FETUS; INDOMETHACIN; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MODELS, BIOLOGICAL; MUTATION; PREGNANCY; RECEPTORS, PROSTAGLANDIN E;

EID: 0030613757     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/36342     Document Type: Article

References (30)

1. Heymann, M. A. & Rudolph, A. M. Control of the ductus areteriosus. Physiol. Rev. 55, 62-78 (1975).
2. Jager, B. V. & Wollenman, O. J. An anatomical study of the closure of the ductus arteriosus. Am. J. Pathol. 18, 595-613 (1942).
3. Challis, J. R. G., Dilley, S. R., Robinson, J. S. & Thorburn, G. D. Prostaglandins in the circulation of the fetal lamb. Prostaglandins 11, 1041-1046 (1976).
4. 2 concentrations and patent ductus arteriosus in fetal and neonatal lambs. J. Pediatr. 97, 455-461 (1980).
5. Clyman, R. I., Wong, L., Heymann, M. A. & Rudolph, A. M. Responsiveness of the lamb ductus arteriosus to prostaglandins and their metabolites. Prostaglandins 15, 325-331 (1980).
6. Mitchell, M. D., Brunt, J., Clover, L. & Walker, D. W. Prostaglandins in the umbilical and uterine circulations during late pregnancy in the ewe. J. Reprod. Fertil. 58, 283-287 (1980).
7. Piper, P. J., Vane, J. R. & Wyllie, J. H. Inactivation of prostaglandins by the lungs. Nature 225, 600-603 (1970).
8. Patterson, D. F. Genetic factors in persistence of the ductus arteriosus. Paediatr. Cardiol. 2, 45-57 (1979).
9. Gersony, W. M. Patent ductus arteriosus in the neonate. Pediatr. Clin. North. Am. 33, 545-560 (1986).
10. Gittenberger-de Groot, A. C., Strengers, J. L. M., Menlink, M., Poelmann, R. E. & Patterson, D. F. Histologic studies on normal and persistent ductus arteriosus in the dog. J. Am. Coll. Cardiol. 6, 394-404 (1985).
11. 2 on the ductus arteriosus in the newborn rat: An ultrastructural study. Physiological Reviews 41, 323-329 (1992).
12. Coceani, F. & Olley, P. M. The response of the ductus arteriosus to prostaglandins. Can. J. Physiol. Pharmacol. 51, 220-225 (1973).
13. Christiansen, N. C. & Fabricus, J. Medical manipulation of the ductus arteriosus. Lancet 2, 24-26 (1975).
14. Elliot, R. B., Starling, M. B. & Neutze, J. M. Medical manipulation of the ductus arteriosus. Lancet 1, 140-142 (1975).
15. Olley, P. M., Coceani, F. & Bocach, E. E-type prostaglandins: A new emergency therapy for certain types of congenital heart malformations. Circulation 53, 728-731 (1976).
16. Sharpe, G. L., Larsson, K. S. & Thalme, B. Studies on closure of the ductus arteriosus. Prostaglandins 9, 585-596 (1975).
17. Moise, K. J. et al. Indomethacin in the treatment of premature labor. Effects on the fetal ductus arteriosus. N. Engl. J. Med. 319, 327-331 (1988).
18. Momma, K. & Takao, A. In vivo constriction of the ductus arteriosus by nonsteroidal anti-inflammatory drugs in near-term and preterm fetal rats. Pediatr. Res. 22, 567-572 (1987).
19. Heymann, M. A., Rudolph, A. M. & Silverman, N. H. Closure of the ductus arteriosus in premature infants by inhibition of prostaglandin synthesis. N. Engl. J. Med. 295, 530-533 (1976).
20. Friedman, W. F., Hirschklau, M. J., Printz, M. P., Pitlick, P. T. & Kirkpatrick, S. E. Pharmacologic closure of patent ductus arteriosus in the premature infant. N. Engl. J. Med. 295, 526-529 (1976).
21. Coleman, R. A., Smith, W. L. & Narumiya, S. International union of pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Phamacol. Rev. 46, 205-229 (1994).
22. Smith, G. C. S., Coleman, R. A. & McGrath, J. C. Characterization of dilator prostanoid receptors in the fetal rabbit ductus arteriosus. J. Pharmacol. Exp. Ther. 271, 390-396 (1994).
23. Coceani, F. Control of the ductus arteriosus - a new function for cytochrome P450, endothelin and nitric oxide. Biochem. Pharmacol. 48, 1315-1318 (1994).
24. Clyman, R. I. Ductus arteriosus: Current theories of prenatal and postnatal regulation. Sem. Perinatol. 11, 64-71 (1987).
25. Coceani, F. & Olley, P. M. Role of prostaglandins, prostacyclins, and thromboxanes in the control of prenatal patency and postnatal closure of the ductus arteriosus. Sem. Perinatol. 4, 109-113 (1980).
26. 2 subtype. J. Biol. Chem. 268, 7759-7762 (1993).
27. 2 subtype. Mol. Pharmacol. 46, 213-220 (1994).
28. Engelhardt, J. F., Yankaskas, J. R. & Wilson, J. M. In vivo retroviral gene transfer into human bronchial epithelia of xenografts. J. Clin. Invest. 90, 2598-2607 (1992).
29. Hooper, M., Hardy, K., Handyside, A., Hunter, S. & Monk, M. HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells. Nature 326, 292-295 (1987).
30. Mohn, A. & Koller, B. H. in DNA Cloning 4 (eds Glover, D. M. & Hames, B. D.) 143-184 (Oxford University Press, New York, 1995).