Tachykinins and neuropsychiatric disorder

Current Drug Targets

Volumn 7, Issue 8, 2006, Pages 993-1003

  Chahl, Loris A ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

Analgesic; Antidepressant; Antiemetic; Antipsychotic; NK1 receptor antagonist; Substance P; Tachykinin; Tachykinin antagonist

Indexed keywords

2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; 2 BENZHYDRYL 3 (2 METHOXYBENZYLAMINO) 1 AZABICYCLO[2.2.2]OCTANE; 3 (2 METHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; ANALGESIC AGENT; ANTIDEPRESSANT AGENT; APREPITANT; CISPLATIN; DEXAMETHASONE; EZLOPITANT; FLUOXETINE; LANEPITANT; NALTREXONE; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; NEUROKININ 2 RECEPTOR; NEUROKININ 2 RECEPTOR ANTAGONIST; NEUROKININ 3 RECEPTOR; NEUROKININ 3 RECEPTOR ANTAGONIST; NEUROKININ A; NEUROKININ B; NEUROTRANSMITTER; NOLPITANTIUM; OSANETANT; PAROXETINE; SAREDUTANT; SUBSTANCE P; TACHYKININ; TACHYKININ RECEPTOR ANTAGONIST; TALNETANT; UNINDEXED DRUG; NEUROLEPTIC AGENT;

ANALGESIA; ANIMAL BEHAVIOR; CANCER; CHEMOTHERAPY INDUCED EMESIS; CLINICAL TRIAL; DEPRESSION; DRUG ABUSE; DRUG ACTIVITY; DRUG EFFICACY; ELECTROPHYSIOLOGY; HUMAN; IMMUNOCOMPETENT CELL; INHIBITION KINETICS; MENTAL DISEASE; MOOD DISORDER; NERVOUS SYSTEM; NEUROLOGIC DISEASE; NOCICEPTION; NONHUMAN; PAIN; PARKINSON DISEASE; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; REVIEW; SCHIZOPHRENIA; SENSORY NERVE; SPINAL CORD DORSAL HORN; ANIMAL; CHEMISTRY; METABOLISM;

ANIMALS; ANTIDEPRESSIVE AGENTS; ANTIPSYCHOTIC AGENTS; HUMANS; MENTAL DISORDERS; TACHYKININS;

EID: 33747163946     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945006778019309     Document Type: Review

References (209)

1. von Euler, U.S. and Gaddum, J.H. (1931) J. Physiol., 72, 74-87.
2. Chang, M.M. and Leeman S.E. (1970) J. Biol. Chem., 245, 4784-4790.
3. Chang, M.M.; Leeman, S.E. and Niall, H.D. (1971) Nature, New Biol., 232, 86-87.
4. Hökfelt, T.; Johansson, O.; Kellerth, J.-O.; Ljungdahl, A.; Nilsson, G.; Nygards, A. and Pernow, B. (1977) In Substance P, (von Euler, U.S. and Pernow, B. Eds), Raven Press, New York, pp. 117-145.
5. Ljungdahl, A.; Hokfelt, T. and Nilsson, G. (1978) Neuroscience, 3, 861-943.
6. Severini, C.; Improta, G.; Falconieri-Erspamer, G.; Salvadori, S. and Erspamer, V. (2002) Pharmacol. Rev., 54, 285-322.
7. Maggi, C.A. (1997) Regul. Pept., 70, 75-90.
8. Pennefather, J.N.; Lecci, A.; Luz Candenas, M.; Patak, E.; Pinto, F.M. and Maggi, C.A. (2004) Life Sci., 74, 1445-1463.
9. Page, N.M. (2004) Cell. Mol. Life Sci., 61, 1652-1663.
10. Bannon, M.J.; Poosch, M.S.; Haverstick, D.M.; Mandal, A.; Xue, I.C.; Shibata, I. and Dragovic, L.J. (1992) Mol. Brain Res., 12, 225-231.
11. Nakanishi, S. (1987) Physiol. Rev., 67, 1117-1142.
12. Bolam, J.P.; Somogyi, P.; Takagi, H.; Fodor, I. and Smith, A.D. (1983) J. Neurocytol., 12, 325-344.
13. Roberts, G.W.; Woodhams, P.L.; Polak, J.M. and Crow, T.J. (1984) Neuroscience, 11, 35-77.
14. Davies, S. and Köhler, C. (1985) Anat. Embryol., 173, 45-52.
15. Menetrey, D. and Basbaum, A.I. (1987) Neuroscience, 23, 173-187.
16. Iritani, S.; Fujii, M. and Satoh, K. (1989) Brain Res. Bull., 22, 295-303.
17. Penny, G.R.; Afsharpour, S. and Kitai, S.T. (1986) Neurosci. Letts., 65, 53-59.
18. Chan-Palay, V.; Jonsson, G. and Palay, S.L. (1978) Proc. Natl. Acad. Sci. USA, 75, 1582-1586.
19. Mâgoul, R.; Onteniente, B.; Oblin, A. and Calas, A. (1986) J. Histochem. Cytochem., 34, 735-742.
20. Costa, M.; Furness, J. and Gibbins I. (1986) Prog. Brain Res., 68, 217-239.
21. Kanazawa, I. and Jessell, T. (1976) Brain Res., 117, 362-367.
22. Douglas, F.L.; Palkovits, M. and Brownstein, M.J. (1982) Brain Res., 245, 376-378.
23. Beach, T.G. and McGeer, E.G. (1984) Neuroscience, 13, 29-52.
24. Halliday, G.M.; Gai, W.P.; Blessing, W.W. and Geffen, L.B. (1990) Neuroscience, 39, 81-96.
25. Hökfelt, T.; Meyerson, B.; Nilsson, G.; Pernow, B. and Sachs, C. (1976) Brain Res., 104, 181-186.
26. Mai, J.K.; Stephens, P.H.; Hopf, A. and Cuello, A.C. (1986) Neuroscience, 17, 709-739.
27. Del Fiacco, M.; Levanti, M.C.; Dessi, M.L. and Zucca, G. (1987) Neuroscience, 21, 141-150.
28. Gale, J.S.; Bird, E.D.; Spoke, E.G.; Iversen, L.L. and Jessell, T. (1978) J. Neurochem., 30, 633-634.
29. Emson, P.C.; Arregul, A.; Clement Jones, V.; Sandberg, B.E. and Rossor, M. (1980) Brain Res., 199, 147-160.
30. Cooper, P.E.; Fernstrom, M.H.; Rorstad, O.P.; Leeman, S.E. and Martin, J.B. (1981) Brain Res., 218, 219-232.
31. Kotani, H.; Hoshimaru, M.; Nawa, H. and Nakanishi, S. (1986) Proc. Natl. Acad. Sci. USA, 83, 7074-7078.
32. Pinto, F.M.; Almeida, T.A.; Hernandez, M.; Devillier, P.; Advenier, C. and Luz Candenas, M. (2004) Eur. J. Pharmacol., 494, 233-239.
33. Harmar, A. and Keen, P. (1982) Brain Res., 231, 379-385.
34. Krause, J.E.; Chirgwin, J.M.; Carter, M.S.; Xu, Z.S. and Hershey, A.D. (1987) Proc. Natl. Acad. Sci. USA, 84, 881-885.
35. Maggi, C.A.; Patacchini, R.; Rovero, P. and Giachetti, A. (1993) J. Autonom. Pharmacol., 13, 23-93.
36. Otsuka, M. and Yoshioka, K. (1993) Physiol. Rev., 73, 229-308.
37. Regoli, D.; Boudon, A. and Fauchêre, J-L. (1994) Pharmacol. Rev., 46, 551-599.
38. Maggi, C.A. (1995) Gen. Pharmacol., 26, 911-944.
39. Nakanishi, S. (1991) Ann. Rev. Neurosci., 14, 123-136.
40. Guard, S. and Watson, S.P. (1991) Neurochem. Int. 18, 149-165.
41. Khawaja, A.M. and Rogers, D.F. (1996) Int. J. Biochem. Cell Biol., 28, 721-738.
42. Nakajima, Y.; Tsuchida, Y.; Negishi, M.; Ito, S. and Nakanishi, S. (1992) J. Biol. Chem. 267, 2437-2442.
43. Fong, T.M.; Anderson, S.A.; Yu, H.; Huang, R.R.C. and Strader, C.D. (1992) Mol. Pharmacol., 41, 24-30.
44. Caberlotto, L.; Hurd, Y.L.; Murdock, P.; Wahlin, J.P.; Melotto, S.; Corsi, M. and Carletti, R. (2003) Eur. J. Neurosci., 17, 1736-1746.
45. Candenas, M.L.; Cintado, C.G.; Pennefather, J.N.; Pereda, M.T.; Loizaga, J.M.; Maggi, C.A. and Pinto, F.M. (2002) Life Sci., 72, 269-277.
46. Belluci, F.; Meini, S.; Catalioto, R-M.; Catalani, C.; Giuliani, S.; Quartara, L.; Giolitti, A.; Faiella, A.; Rotondaro, L.; Candenas, M.L.; Pinto, F.M. and Maggi, C.A. (2004) Eur. J. Pharmacol., 499, 229-238.
47. Petitet, F.; Beaujouan, J-C.; Saffroy, M.; Torrens, Y.; Fardin, V. and Glowinski, J. (1993) Peptides, 14, 551-559.
48. Dam, T-V. and Quirion, R. (1994) In The Tachykinin Receptors, (Buck, S.H., Ed.), Humana, New Jersey, pp. 101-123.
49. Ding, Y.Q.; Shigemoto, R.; Takada, M.; Ohoshi, H.; Nakanishi, S. and Mizuno, N. (1996) J. Comp. Neurol., 364, 290-310.
50. Nakaya, Y.; Kaneko, T.; Shigemoto, R.; Nakanishi, S. and Mizuno, N. (1994) J. Comp. Neurol., 347, 249-274.
51. Mileusnic, D.; Lee, J.M.; Magnuson, D.J.; Hejna, M.J.; Krause, J.E.; Lorens, J.B. and Lorens, S.A. (1999) Neuroscience, 89, 1269-1290.
52. Yip, J. and Chahl L.A. (2001) Regul. Pept., 98, 55-62.
53. Tooney, P.A.; Au, G.G. and Chahl, L.A. (2000) Neurosci. Letts., 283, 185-188.
54. Snider, R.M.; Constantine, J.W.; Lowe III, J.A.; Longo, K.P.; Lebel, W.S.; Woody, H.A.; Drozda, S.E.; Desai, M.C.; Vinick, F.J.; Spencer, R.W. and Hess, H.J. (1991) Science, 251, 435-437.
55. McLean, S.; Gangon, A.H.; Seeger, T.F.; Bryce, D.K.; Pratt, K.G.; Reynolds, L.S.; Stok, C.J.; Lowe III, J.A. and Heym, J. (1991) Science, 251, 437-439.
56. Guard, S. and Watling, K.J. (1992) Br. J. Pharmacol., 106, 37P.
57. Garret, C.; Carruette, A.; Fardin, V.; Moussaoui, S.; Peyronel, J.F.; Blanchard, J.C.; and Laduron, P.M. (1991) Proc. Natl. Acad. Sci. USA, 88, 10208-10211.
58. Saria, A. (1999) Eur. J. Pharmacol., 375, 51-60.
59. Gorbulev, V.; Akhundora, A.; Luzins, H. and Fahrenholz, F. (1992) Biochim. Biophys. Acta, 1131, 99-102.
60. Emonds-Alt, X.; Vilain, P.; Goulaouic, P.; Proietto, V.; Van Broeck, D.; Advenier, C.; Naline, E.; Neliat, G.; Le Fur, G. and Breliere, J.C. (1992) Life Sci., 50, PL101-PL106.
61. Advenier, C.; Rouissi, N.; Nguyen, Q.T.; Emonds-Alt, X.; Breliere, J.C.; Neliat, G.; Naline, E. and Regoli, D. (1992) Biochem. Biophys. Res. Commun., 184, 1418-1424.
62. Emonds-Alt, X.; Doutremepuich, J.D.; Jung, M.; Proietto, V.; Santucci, V.; Van Broeck, D.; Vilain, P.; Soubrie, P.; Le Fur, G. and Breliere, J.C. (1993) Neuropeptides, 24, 231-239.
63. Emonds-Alt, X.; Bichon, D.; Ducoux, J.P.; Heaulme, M.; Miloux, B.; Poncelet, M.; Proietto, V.; Van Broeck, D.; Vilain, P.; Neliat, G.; Soubrie, P.; Le Fur, G. and Breliere, J.C. (1995) Life Sci., 56, PL27-PL32.
64. Seabrook, G.R.; Shepheard, S.L., Williamson, D.J.; Tyrer, P.; Rigby, M.; Cascieri, M.A.; Harrison, T.; Hargreaves, R.J. and Hill, R.G. (1996) Eur. J. Pharmacol., 317, 129-135.
65. Kramer, M.S.; Cutler, N.; Feighner, J.; Shrivastava, R.; Carman, J.; Sramek, J.J.; Reines, S.A.; Liu, G.; Snavely, D.; Wyatt-Knowles, Edwina; Hale, Jeffrey J.; Mills, S.G.; MacCoss, M.; Swain, C.J.; Harrison, T.; Hill, R.G.; Hefti, F.; Scolnick, E.M.; Cascieri, M.A.; Chicchi, G.G.; Sadowski, S.; Williams, A.R.; Hewson, L.; Smith, D.; Carlson, E.J.; Hargreaves, R.J.; and Rupniak, N.M.J. (1998) Science, 281, 1640-1645.
66. Emonds-Alt, X.; Proietto,V.; Steinberg, R.; Advenier, C.; Daoui, S.; Naline, E.; Gueudet, C.; Michaud, J-C.; Oury-Donat, F.; Poncelet, M.; Vilain, P.; Le Fur, G.; Mattrand, J-P.; Soubrio, P. and Pascal, M. (2002) Can. J. Physiol. Pharmacol., 80, 482-88.
67. Quartara, L. and Maggi, C.A. (1997) Neuropeptides, 31, 537-563.
68. Lembeck. F. (1953) Arch. Exp. Pathol. Pharmakol. 219, 197-213.
69. Hökfelt, T.; Kellerth, J.O.; Nilsson, G. and Pernow, B. (1975) Brain Res., 100, 235-252.
70. Hökfelt, T., Kellerth, J.O., Nilsson, G., and Pernow, B. (1975) Science, 190, 889-890.
71. Hökfelt, T.; Ljungdahl, A.; Terenius, L.; Elde, R. And Nilsson, G. (1977) Proc. Natl. Acad. Sci. USA, 74, 3081-3085.
72. Jancso, G.; Kiraly, E. and Jancso-Gabor, A. (1977) Nature, 270, 741-743.
73. Maggi, C.A. and Meli, A. (1988) Gen. Pharmacol., 19, 1-43.
74. Ogawa, T.; Kanazawa, I. and Kimura, S. (1985) Brain Res., 359, 152-157.
75. McLeod, A.L.; Krause, J.E. and Ribeiro-Da-Silva, A. (2000) J. Comp. Neurol., 420, 349-362.
76. Murase, K. and Randic, M. (1984) J. Physiol. (Lond.), 346, 203-217.
77. Henry, J.L. (1976) Brain Res., 114, 439-451.
78. Wiesenfeld-Hallin, Z. (1986) Brain Res., 372, 172-175.
79. Leah, J.D.; Cameron, A.A. and Snow, P.J. (1985) Neurosci. Letts., 56, 257-263.
80. Neumann, S.; Doubell, T.P.; Leslie, T. and Woolf, C.J. (1996) Nature, 384, 360-364.
81. Hylden, J.K.L. and Wilcox, G.L. (1981) Brain Res., 217, 212-215.
82. Lembeck, F.; Folkers, K. and Donnerer, J. (1981) Biochem. Biophys. Res. Commun., 103, 1318-1321.
83. Otsuka, M. and Yanagisawa, M. (1990) Cell. Mol. Neurobiol., 10, 293-302.
84. Stewart, J.M.; Gretto, C.J.; Neldner, K.; Reeve, B.; Krivoy, W. and Zimmermann, M. (1976) Nature, 262, 784-785.
85. Frederickson, R.C.; Burgis, V.; Harrell, C.E. and Edwards, J.D. (1978) Science, 199, 1359-1362.
86. Duggan, A.W. and Hendry, I.A. (1986) Neurosci. Letts., 68, 134-140.
87. McCarson, K.E. and Goldstein, B.D. (1991) Brain Res., 568, 109-115.
88. Schaible, H.G.; Jarrott, B.; Hope, P.J. and Duggan, A.W. (1990) Brain Res., 529, 214-223.
89. Ninkovic, M.; Beaujouan, J-C.; Torrens, Y.; Saffroy, M.; Hall, M.D. and Glowinski, J. (1984) Eur. J. Pharmacol., 106, 463-464.
90. Yashpal, K.; Radhakrishnan, V.; Coderre, T.J. and Henry, J.L. (1993) Neuroscience, 52, 1039-1047.
91. Mantyh, P.W.; Rogers, S.D.; Honore, P.; Allen, B.J.; Ghilardi, J.R.; Li, J.; Daughters, R.S.; Lappi, D.A.; Wiley, R.G. and Simone, D.A. (1997) Science, 278, 275-279.
92. Mendell, L.M. and Wall, P.D. (1966) Nature, 206, 97-99.
93. Khasabov, S.G.; Rogers, S.D.; Ghilardi, J.R.; Peters, C.M.; Mantyh, P.W. and Simone, D.A. (2002) J. Neurosci., 22, 9086-9098.
94. Urban, L.; Thompson, S.W. and Dray, A. (1994) Trends Neurosci., 17, 432-438.
95. Budai, D and Larson, A.A. (1996) Brain Res., 710, 197-203.
96. Picard, P.; Boucher, S.; Regoli, D.; Gitter, B.D.; Howbert, J.J. and Couture, R. (1993) Eur. J. Pharmacol., 232, 255-261.
97. Jia, Y.P. and Seybold, V.S. (1997) Brain Res., 751, 169-174.
98. Ding, Y-Q.; Lu, C-R.; Wang, H.; Su, C-J.; Chen, L-W.; Zhang, Y-Q. and Ju, G. (2002) Eur. J. Neurosci., 16, 551-556.
99. Barbieri, M. and Nistri, A. (2001) J. Neurophysiol., 85, 1502-1511.
100. Battaglia, G. and Rustioni, A. (1998) J. Comp. Neurol., 277, 302-312.
101. Grubb, B.D.; Riley, R.C.; Hope, P.J.; Pubols, L. and Duggan, A.W. (1996) Neuroscience, 74, 1077-1086.
102. Fürst, S. (1999) Brain Res. Bull., 48, 129-141.
103. Soyguder, Z. (2005) Brain Res., 1033, 202-209.
104. De Felipe, C.; Herrero, J.F.; O'Brien, J.A.; Palmer, J.A.; Doyle, C.A.; Smith, A.J.; Laird, J.M.; Belmonte, C.; Cervero, F. and Hunt, S.P. (1998) Nature, 392, 394-397.
105. Cao, Y-Q.; Mantyh, P.W.; Carlson, E.J.; Gillespie, A.M.; Epstein, C.J. and Basbaum, A.I. (1998) Nature, 392, 390-394.
106. Zimmer, A.; Zimmer, A.M.; Baffi, J.; Usdin, T.; Reynolds, K.; Konig, M.; Palkovits, M. and Mezey, E. (1998) Proc. Natl. Acad. Sci. USA, 95, 2630-2635.
107. Martin, W.J.; Cao, Y-Q. and Basbaum, A.I. (2004) J. Neurophysiol., 91, 1945-1954.
108. McLeod, A.L.; Ritchie, J.; Cuello, A.C.; Julien, J-P.; Ribeiro-Da-Silva, A. and Henry, J.L. (1999) Neuroscience, 89, 891-899.
109. Weng, H-R; Mansikka, H.; Winchurch, R.; Raja, S.N. and Dougherty, P.M. (2001) Anesthesiology, 94, 1105-1112.
110. Kidd, B.L.; Inglis, J.J.; Vetsika, K.; Hood, V.C.; De Felipe, C.; Bester, H.; Hunt, S.P. and Cruwys, S.C. (2003) Neuroreport, 14, 2189-2192.
111. Kennedy, P.G.E.; Rodgers, J.; Bradley, B.; Hunt, S.P.; Gettinby, G.; Leeman, S.E.; De Felipe, C. and Murray, M. (2003) Brain, 126, 1683-1690.
112. Hill, R. (2000) Trends Pharmacol. Sci., 21, 244-246.
113. Urban, L.A. (2000) Trends Pharmacol. Sci., 21, 462-464.
114. Villanueva, L. (2000) Trends Pharmacol. Sci., 21, 461-462.
115. Hill, R. (2000) Trends Pharmacol. Sci., 21, 465.
116. Hargreaves, R. (2002) J. Clin. Psychiatry, 63 (Suppl. 11), 18-24.
117. Vera-Portocarrero, L.P. and Westlund, K.N. (2004) Pharmacol. Biochem. Behav., 77, 63-640.
118. Fioramonti, J.; Gaultier, E.; Toulouse, M.; Sanger, G.J. and Bueno, L. (2003) Neurogastroenterol. Motil., 15, 363-369.
119. Maeono, H.; Kiyama, H. and Tohyama, M. (1993) Mol. Brain Res., 18, 43-58.
120. Kelley, A.E.; Stinus, L. and Iversen, S.D. (1979) Neurosci. Letts., 11, 335-339.
121. Elliott, P.J. and Iversen, S.P. (1986) Brain Res., 381, 68-76.
122. Elliott, P.J. (1988) Exp. Brain Res., 381, 354-356.
123. Unger, T.; Carolus, S.; Demmert, G.; Ganten, D.; Lang, R.E.; Maser-Gluth, C.; Steinberg, H. and Veelken, R. (1998) Circ. Res., 63, 812-820.
124. Culman, J.; Klee, S.; Ohlendorf, C. and Unger, T. (1997) J. Pharmacol. Exp. Ther., 280, 238-246.
125. Rupniak, N.M. and Williams, A.R. (1994) Eur. J. Pharmacol., 265, 179-183.
126. Ballard, T.M.; Sanger, S. and Higgins, G.A. (2001) Eur. J. Pharmacol., 412, 255-264.
127. Varty, G.B.; Cohen-Williams, M.E.; Morgan, C.A.; Pylak, U.; Duffy, R.A.; Lachowicz, J.E.; Carey, G.L. and Coffin, V.L. (2002) Neuropsychopharmacology, 27, 371-379.
128. File, S.E. (1997) Pharmacol. Biochem. Behav., 58, 747-752.
129. Johnston, P.A. and Chahl, L.A. (1991) Naunyn-Schmiedeberg's Arch. Pharmacol., 343, 283-288.
130. Johnston, P.A. and Chahl, L.A. (1993) Regul. Peptides, 46, 376-378.
131. Yip, J and Chahl, L.A. (1997) Br. J. Pharmacol., 122, 715-725.
132. Yip, J. and Chahl, L.A. (1999) Neuroscience, 94, 663-673.
133. Piot, O.; Betschart, J.; Grall, I.; Ravard, S.; Garret, C. and Blanchard, J-C. (1995) Br. J. Pharmacol., 116, 2496-2502.
134. Kramer, M.S.; Cutler, N.; Feighner, J.; Shrivastava, R.; Carman, J.; Sramek, J.J.; Reines, S.A.; Liu, G.; Snavely, D.; Wyatt-Knowles, E.; Hale, J.J.; Mills, S.G.; MacCoss, M.; Swai, C.J.; Harrison, T.; Hill, R.G.; Hefti, F.F.; Scolnick, E.M.; Cascieri, M.A.; Chicchi, G.G.; Sadowski, S.; Williams, A.R.; Hewson, L.; Smith, D.; Carlson, E.J.; Hargreaves, R.J. and Rupniak, N.M.J. (1998) Science, 281, 1640-1645.
135. Rupniak, N.M.; Carlson, E.C.; Harrison, T.; Oates, B.; Seward, E.; Owen, S.; De Felipe, C.; Hunt, S. and Wheeldon, A. (2000) Neuropharmacology, 39, 1413-1421.
136. Krishnan, K.R.R. (2002) J. Clin. Psychiatry, 63 (Suppl. 11), 25-29.
137. Rupniak, N.M.J. (2002) Can. J. Physiol. Pharmacol., 80, 489-494.
138. Adell, A. (2004) Current Drug Targets - CNS & Neurological Disorders, 3, 113-121.
139. Conley, R.K.; Cumberbatch, M.J.; Mason, G.S.; Williamson, D.J.; Harrison, T.; Locker, K.; Swain, C.; Maubach, K.; O'Donnell, R.; Rigby, M.; Hewson, L.; Smith, D. and Rupniak, N.M. (2002) J. Neurosci., 22, 7730-7736.
140. Guiard, B.P.; Przybylski, C.; Guilloux, J-P.; Seif, I.; Froger, N.; De Felipe, C.; Hunt, S.P.; Lanfumey, L. and Gardier, A.M. (2004) J. Neurochem., 89, 54-63.
141. Maubach, K.A.; Martin, K.; Chicchi, G.; Harrison, T.; Wheeldon, A.; Swain, C.J.; Cumberbatch, M.J.; Rupniak, N.M. and Seabrook, G.R. (2002) Neuroscience, 109, 609-617.
142. Smith, D.W.; Hewson, L.; Fuller, P.; Williams, A.R.; Wheeldon, A. and Rupniak, N.M. (1999) Brain Res., 848, 90-95.
143. Boyce, S.; Smith, D.; Carlson, E.; Hewson, L.; Rigby, M.; O'Donnell, R.; Harrison, T. and Rupniak, N.M. (2001). Neuropharmacology, 41, 130-137.
144. Maubach, K.A.; Martin, K.; Smith, D.W.; Hewson, L.; Frankshun, R.A.; Harrison, T. and Seabrook, G.R. (2001) Neuropharmacology, 40, 806-817.
145. Ebner, K.; Rupniak, N.M.; Saria, A. and Singewald, N. (2004) Proc. Natl. Acad. Sci. USA, 101, 4280-4285.
146. Jacobs, B.L.; Praag, H. and Gage, F.H. (2000) Mol. Psychiatry, 5, 262-269.
147. van der Hart, M.G.; Czeh, B.; de Biurrun, G.; Michaelis, T.; Watanabe, T.; Natt, O.; Frahm, J. and Fuchs, E. (2002) Mol. Psychiatry, 7, 933-941.
148. Guest, P.C.; Knowles, M.R.; Molon-Noblot, S.; Salim, K.; Smith, D.; Murray, F.; Laroque, P.; Hunt, S.P.; De Felipe, C.; Rupniak, N.M. and McAllister, G. (2004) Brain Res., 1002, 1-10.
149. Stout, S.C.; Owens, M.J. and Nemeroff, C.B. (2001) Annu. Rev. Pharmacol. Toxicol., 41, 877-906.
150. Burnet, P.W. and Harrison, P.J. (1999) Biol. Psychiatry, 47, 80-83.
151. Walsh, D.M.; Stratton, S.C.; Beresford, I.J. and Hagan, R.M. (1995) Psychopharmacology, 121, 186-191.
152. Dableh, L.J.; Yashpal, K.; Rochford, J. and Henry, J.L. (2005) Eur. J. Pharmacol., 507, 99-105.
153. Suman-Chauhan, N.; Grimson, P.; Guard, S.; Madden, Z.; Chung, F.Z.; Watling, K.; Pinnock, R. and Woodruff, G. (1994) Eur. J. Pharmacol., 269, 65-72.
154. Massi, M.; Panocka, I. and de Caro, G. (2000) Peptides, 21, 1597-1609.
155. Ribeiro, S.J.; Teixeira, R.M.; Calixto, J.B. and Lima, T.V. (1999) Neuropeptides, 33, 181-188.
156. Armstrong, D.M.; Pickel, V.M.; Joh, T.H.; Reis, D.J. and Miller, R.J. (1981) J. Comp. Neurol., 196, 505-517.
157. Helke, C.J.; Shults, C.A.; Chase, T.N. and O'Donohue, T.L. (1984) Neuroscience, 12, 215-223.
158. Ladic, L.A. and Buchan, A.M.J. (1996) J. Autonom. Nervous System, 58, 25-34.
159. Quartara, L. and Maggi, C.A. (1998) Neuropeptides, 32, 1-49.
160. Bountra, C.; Bunce, K.; Dale, T.; Gardner, C.; Jordan, C.; Twissell, D. and Ward, P. (1993) Eur. J. Pharmacol., 249, R3-R4.
161. Tattersall, F.D.; Rycroft, W.; Hargreaves, R.J. and Hill, R.G. (1993) Eur. J. Pharmacol., 250, R5-R6.
162. Watson, J.W.; Gonsalves, S.F.; Fossa, A.A.; McLean, S.; Seeger, T.; Obach, S. and Andrews, P.L. (1995) Br. J. Pharmacol., 115, 84-94.
163. Rudd, J.A.; Jordan, C.C. and Naylor, R.J. (1996) Br. J. Pharmacol., 119, 931-936.
164. Lucot, J.B.; Obach, R.S.; McLean, S. and Watson, J.W. (1997) Br. J. Pharmacol., 120, 116-120.
165. Gardner, C.J.; Twissell, D.J.; Dale, T.J.; Gale, J.D.; Jordan, C.C.; Kilpatrick, G.J.; Bountra, C. and Ward, P. (1995) Br. J. Pharmacol., 116, 3158-3163.
166. Grelot, L.; Dapzol, J.; Esteve, E.; Frugiere, A.; Bianchi, A.L.; Sheldrick, R.L.; Gardner, C.J. and Ward, P. (1998) Br. J. Pharmacol., 124, 1643-1650.
167. Singh, L.; Field, M.J.; Hughes, J.; Kuo, B-S.; Suman-Chauhan, N.; Tuladhar, B.R.; Wright, D.S. and Naylor, R.J. (1997) Eur. J. Pharmacol., 321, 209-216.
168. Gonsalves, S.; Watson, J. and Ashton, C. (1996) Eur. J. Pharmacol., 306, 181-185.
169. Rupniak, N.M.J.; Tattersall, F.D.; Williams, A.R.; Rycroft, W.; Carlson, E.J.; Cascieri, M.A.; Sadowski, S.; Ber, E.; Hale, J.J.; Mills, S.G.; MacCoss, M.; Seward, E.; Huscroft, I.; Owen, S.; Swain, C.J.; Hill, R.G. and Hargreaves, R.J. (1997) Eur. J. Pharmacol., 326, 201-209.
170. Tattersall, F.D.; Rycroft, W.; Francis, B.; Pearce, D.; Merchant, K.; MacLeod, A.M.; Ladduwahetty, T.; Keown, L.; Swain, C.; Baker, R.; Cascieri, M.; Ber, E.; Metzger, J.; MacIntyre, D.E.; Hill, R.G. and Hargreaves, R.J. (1996) Neuropharmacology, 35, 1121-1129.
171. Rupniak, N.M.J. and Kramer, M.S. (1999) Trends Pharmacol. Sci., 20, 485-490.
172. Hesketh, P.J.; Grunberg. S.M.; Gralla, R.J.; Warr, D.G.; Roila, F.; de Wit, R.; Chawla. S.P.; Carides, A.D.; Ianus, J.; Elmer, M.E.; Evans, J.K.; Beck, K.; Reines, S. and Horgan, K.J. Aprepitant Protocol 052 Study Group (2003) J. Clin. Oncology, 21, 4112-4119.
173. de Wit, R.; Herrstedt, J.; Rapoport, B.; Carides, A.D.; Carides, G.; Elmer, M.; Schmidt, C.; Evans, J.K. and Horgan, K.J. (2003) J. Clin. Oncology, 21, 4105-4111.
174. de Wit, R.; Herrstedt, J.; Rapoport, B.; Carides, A.D.; Guoguang-Ma, J.; Elmer, M.; Schmidt, C.; Evans, J.K. and Horgan, K.J. (2004) Eur. J. Cancer, 40, 403-410.
175. Navari, R.M. (2004) Cancer Investig., 22, 569-576.
176. Massaro, A.M. and Lenz, K.L. (2005) Annals Pharmacother., 39, 77-85.
177. Sanchez, R.I.; Wang, R.W.; Newton, D.J.; Bakhtiar, R.; Lu, P.; Chiu, S.H.; Evans, D.C. and Huskey, S.E. (2004) Drug Metab. Dispos., 32, 1287-1292.
178. Shadle, C.R.; Lee, Y.; Majumdar, A.K.; Petty, K.J.; Gargano, C.; Bradstreet, T.E.; Evans, J.K. and Blum, R.A. (2004) J. Clin. Pharmacol., 44, 215-223.
179. http://www.medicinenet.com/aprepitant-oral/article.htm
180. Kaiya, H.; Tamura, Y.; Adachi, S.; Moriuchi, I.; Namba, M.; Tanaka, M.; Yoshida, H.; Yanaihara, N.; and Yanaihara, C. (1981) Psychiatry Res., 5, 11-21.
181. Rimon, R.; Le Greves, P.; Nyberg, F.; Heikkila, L.; Satmela, L. and Terenius, L. (1984) Biol. Psychiatry, 19, 509-516.
182. Heikkila, L.; Rimon, R. and Terenius, L. (1990) Psychiatry Res., 34, 229-236.
183. Miller, C.; Kirchmair, R.; Troger, J.; Saria, A.; Fleischhacker, W.W.; Fischer-Colbrie, R.; Benzer, A. and Winkler, H. (1996) Biol. Psychiatry, 39, 911-918.
184. Roberts, G.W.; Ferrier, I.N.; Lee, Y.; Crow, T.J.; Johnstone, E.C.; Owens, D.G.C.; Bacarese-Hamilton, A.J.; McGregor, G.; O'Shaughnessey, D.; Polak, J.M. and Bloom, S.R. (1983) Brain Res., 288, 199-211.
185. Toru, M.; Watanabe, S.; Shibuya, H.; Nishikawa, T.; Noda, K.; Mitsushio, H.; Ichikawa, H.; Kurumaji, A.; Takashima, M.; Mataga, N. and Ogawa, A. (1988) Acta Psychiatry Scand., 78, 121-137.
186. Iadarola, M.J.; Ofri, D. And Kleinman, J.E. (1991) Life Sci., 48, 1919-1930.
187. Rioux, L.; Nissanov, J. and Joyce, J.N. (1998) Prog. Neuro-Psychopharmacol. Biol. Psychiatry, 22, 1295-1299.
188. Burnet, P.W. and Harrison, P.J. (2000) Biol. Psychiatry, 47, 80-83.
189. Harrison, P.J. (1999) Brain Res., 122, 593-624.
190. Tooney, P.A.; Crawter, V.C. and Chahl. L.A. (2001) Biol. Psychiatry, 49, 523-527.
191. Tooney, P.A.; Anderson, W.B.; Lynch-Frame, A. and Chahl, L.A. Neurosci. Lett., In press.
192. Elliott, P.J.; Mason, G.S.; Stephens-Smith, M. and Hagan, R.M. (1991) Neuropeptides, 19, 119-126.
193. Seabrook, G.R.; Bowery, B.J. and Hill, R.G. (1995) Eur. J. Pharmacol., 273, 113-119.
194. Whitty, C.J.; Paul, M.A. and Bannon, M.J. (1997) J. Comp. Neurol., 382, 394-400.
195. Bensaid, M.; Faucheux, B.A.; Hirsch, E.; Agid, Y.; Soubrie, P. and Oury-Donat, F. (2001) Neurosci. Letts, 303, 25-28.
196. Meltzer, H.Y.; Arvanitis, L.; Bauer, D.; Rein, W. and Meta-Trial Study Group (2004) Am. J. Psychiatry, 161, 975-984.
197. Giardina, G.A.; Gagliardi, S. and Martinelli, M. (2003) Idrugs, 6, 758-772.
198. Hutson, P.H.; Patel, S.; Jay, M.T. and Barton, C.L. (2004) Eur. J. Pharmacol., 484, 57-64.
199. Smith, Y and J.Z. Kieval (2000) Trends Neurosci., 23, S28-S33.
200. Aubry, J-M.; Lundström, K.; Kawashima, E.; Ayala, G.; Schulz, P.; Bartanusz, V. and Kiss, J.Z. (1994) NeuroReport, 5, 1597-1600.
201. Parent, A.; Cicchetti, F. and Beach, T.G. (1995) NeuroReport, 6, 721-724.
202. Kemel, M-L.; Pérez, S.; Beaujouan, J-C.; Jabourian, M.; Soubrié, P. and Glowinski, J. (2003) J. Neurochem., 87, 487-496.
203. Wade, T.V. and Schneider, J.S. (2004) NeuroReport, 15, 2481-2484.
204. Chen, L.W.; Yung, K.K. and Chan, Y.S. (2004) Current Drug Targets, 5, 197-206.
205. Maldonado, R.; Girdlestone, D. and Roques, B.P. (1993) Neurosci. Letts, 156, 135-140.
206. Hasenöhrl, R.U.; De Souza-Silva, M.A.; Nikolaus, S.; Tomaz, C.; Brandao, M.L.; Schwarting, R.K.W. and Huston, J.P. (2000) Neuropeptides, 34, 272-280.
207. Ripley, T.L.; Gadd, C.A.; De Felipe, C.; Hunt, S.P. and Stephens, D.N. (2002) Neuropharmacology, 43, 1258-1268.
208. Gadd, C.A.; Murtra, P.; De Felipe, C. and Hunt, S.P. (2003) J. Neurosci., 23, 8271-8280.
209. Langosch, J.M.; Kupferschmid, S.; Heinen, M.; Walden, J.; Herpfer, I.; Fiebich, B.L. and Lieb, K. (2005) Prog. Neuro-Psychopharmacol. Biol. Psychiatry, 29, 315-319.