Intestinal anti-nociceptive behaviour of NK3 receptor antagonism in conscious rats: Evidence to support a peripheral mechanism of action

Neurogastroenterology and Motility

Volumn 15, Issue 4, 2003, Pages 363-369

  Fioramonti, Jean ^a   Gaultier, E ^a   Toulouse, M ^a   Sanger, G J ^b   Bueno, L ^a  

^a CEMAGREF   (France)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Colo rectal tone; Inflammation; NK3 receptor; Stress; Visceral pain

Indexed keywords

NEUROKININ 3 RECEPTOR; SB 235375; TACHYKININ RECEPTOR ANTAGONIST; TALNETANT; UNCLASSIFIED DRUG;

ABDOMINAL WALL MUSCULATURE; ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; COLON DILATATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; ELECTRODE; ELECTROMYOGRAPHY; ENTERITIS; FEMALE; HYPERSENSITIVITY; IMMOBILIZATION STRESS; INTESTINE DISTENSION; MALE; MUSCLE CONTRACTION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; STRESS;

ABDOMINAL MUSCLES; ACETIC ACIDS; ANIMALS; BLOOD-BRAIN BARRIER; CONSCIOUSNESS; ELECTROMYOGRAPHY; FEMALE; INTESTINES; MALE; MUSCLE CONTRACTION; NOCICEPTORS; PAIN MEASUREMENT; PHYSICAL STIMULATION; QUINOLINES; RATS; RATS, WISTAR; RECEPTORS, NEUROKININ-3; RECTUM; RESTRAINT, PHYSICAL; STRESS, PSYCHOLOGICAL; TRINITROBENZENESULFONIC ACID;

EID: 0038713723     PISSN: 13501925     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2982.2003.00420.x     Document Type: Article

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