L-733,060, a novel tachykinin NK1 receptor antagonist; effects in [Ca2+](i) mobilisation, cardiovascular and dural extravasation assays

European Journal of Pharmacology

Volumn 317, Issue 1, 1996, Pages 129-135

  Seabrook, Guy R ^a   Shepheard, Sara L ^a   Williamson, David J ^a   Tyrer, Peter ^a   Rigby, Michael ^a   Cascieri, Margaret A ^a   Harrison, Timothy ^a   Hargreaves, Richard J ^a   Hill, Raymond G ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

Migraine; Pain; Plasma extravasation; Substance P; Tachykinin NK1 receptor

Indexed keywords

3 [3,5 BIS(TRIFLUOROMETHYL)BENZYLOXY] 2 PHENYLPIPERIDINE; SUBSTANCE P; TACHYKININ RECEPTOR; TACHYKININ RECEPTOR ANTAGONIST;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM MOBILIZATION; CARDIOVASCULAR EFFECT; CHO CELL; CONTROLLED STUDY; DRUG EFFECT; EXTRAVASATION; GERBIL; HEART RATE; INTRAVENOUS DRUG ADMINISTRATION; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BLOOD PRESSURE; CALCIUM; CAPILLARY PERMEABILITY; CHO CELLS; CRICETINAE; GERBILLINAE; HEART RATE; HEMODYNAMIC PROCESSES; HUMANS; MALE; PIPERIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROKININ-1; STEREOISOMERISM; TRANSFECTION;

EID: 0030581733     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00706-6     Document Type: Article

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