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Volumn 22, Issue 4, 2004, Pages 569-576

Role of neurokinin-1 receptor antagonists in chemotherapy-induced emesis: Summary of clinical trials

Author keywords

5 HT3 receptor antagonists; Antiemetics; Chemotherapy induced emesis; NK 1 receptor antagonists

Indexed keywords

2 [1 [3,5 BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY] 3 (4 FLUOROPHENYL) 4 (3 OXO 1 PHOSPHORYL 1,2,4 TRIAZOL 5 YLMETHYL)MORPHOLINE; 3 (2 METHOXY 5 TRIFLUOROMETHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; APREPITANT; BUTYROPHENONE DERIVATIVE; DEXAMETHASONE; DOLASETRON MESILATE; DOPAMINE RECEPTOR BLOCKING AGENT; DROPERIDOL; EZLOPITANT; GRANISETRON; HALOPERIDOL; METOCLOPRAMIDE; NEUROKININ 1 RECEPTOR ANTAGONIST; ONDANSETRON; PALONESETRON; PHENOTHIAZINE DERIVATIVE; RAMOSETRON; SEROTONIN 3 ANTAGONIST; SEROTONIN ANTAGONIST; SUBSTANCE P ANTAGONIST; TROPISETRON; UNCLASSIFIED DRUG;

EID: 8644250381     PISSN: 07357907     EISSN: None     Source Type: Journal    
DOI: 10.1081/CNV-200027137     Document Type: Review
Times cited : (20)

References (46)
  • 2
    • 0029835209 scopus 로고    scopus 로고
    • Quality of life studies in chemotherapy induced emesis
    • Osba, D.; Zee, B.; Warr, D.; Kaizer, L.; Latreille, J.; Pater, J. Quality of life studies in chemotherapy induced emesis. Oncology 1996, 53 (Suppl 1), 92-95.
    • (1996) Oncology , vol.53 , Issue.SUPPL. 1 , pp. 92-95
    • Osba, D.1    Zee, B.2    Warr, D.3    Kaizer, L.4    Latreille, J.5    Pater, J.6
  • 3
    • 0019457470 scopus 로고
    • Emesis as a critical problem in chemotherapy
    • Laszlo, J.; Lucas, V.S., Jr. Emesis as a critical problem in chemotherapy. N. Engl. J. Med. 1981, 305, 948-949.
    • (1981) N. Engl. J. Med. , vol.305 , pp. 948-949
    • Laszlo, J.1    Lucas Jr., V.S.2
  • 4
    • 0028032299 scopus 로고
    • Efficacy and safety of granisetron, a selective 5-hydroxytryptamine receptor antagonist, for the prevention of nausea and vomiting induced by high dose cisplatin
    • Navari, R.M.; Kaplan, H.G.; Gralla, R.J.; Grunberg, S.M.; Palmer, R.; Fitts, D. Efficacy and safety of granisetron, a selective 5-hydroxytryptamine receptor antagonist, for the prevention of nausea and vomiting induced by high dose cisplatin. J. Clin. Oncol. 1994, 12, 2204-2210.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 2204-2210
    • Navari, R.M.1    Kaplan, H.G.2    Gralla, R.J.3    Grunberg, S.M.4    Palmer, R.5    Fitts, D.6
  • 5
  • 6
    • 0028913581 scopus 로고
    • Review of the preclinical pharmacology and comparative efficacy of 5-hydroxytryptamine-3 receptor antagonists for chemotherapy induced emesis
    • Perez, E.A. Review of the preclinical pharmacology and comparative efficacy of 5-hydroxytryptamine-3 receptor antagonists for chemotherapy induced emesis. J. Clin. Oncol. 1995, 13, 1036-1043.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 1036-1043
    • Perez, E.A.1
  • 7
    • 0029073652 scopus 로고
    • Progress in reducing nausea and emesis. Comparisons of ondansetron, granisetron, and tropisetron
    • Morrow, G.R.; Hickok, J.T.; Rosenthal, S.N. Progress in reducing nausea and emesis. Comparisons of ondansetron, granisetron, and tropisetron. Cancer 1995, 76, 343-357.
    • (1995) Cancer , vol.76 , pp. 343-357
    • Morrow, G.R.1    Hickok, J.T.2    Rosenthal, S.N.3
  • 8
    • 0030032559 scopus 로고    scopus 로고
    • Comparison of granisetron versus ondansetron versus tropisetron in the prophylaxis of acute nausea and vomiting induced by cisplatin for the treatment of head and neck cancer; a randomized controlled trial
    • Mantovani, G.; Maccio, A.; Bianch, A.; Curreli, L.; Ghiani, M.; Proto, E.; Santona, M.C. Comparison of granisetron versus ondansetron versus tropisetron in the prophylaxis of acute nausea and vomiting induced by cisplatin for the treatment of head and neck cancer; a randomized controlled trial. Cancer 1996, 77, 941-948.
    • (1996) Cancer , vol.77 , pp. 941-948
    • Mantovani, G.1    Maccio, A.2    Bianch, A.3    Curreli, L.4    Ghiani, M.5    Proto, E.6    Santona, M.C.7
  • 9
    • 9444264707 scopus 로고    scopus 로고
    • Double blind randomized comparison of the antiemetic efficacy of intravenous dolasetron and intravenous ondansetron in the prevention of acute cisplatin induced emesis in patients with cancer
    • Hesketh, P.; Navari, R.M.; Grote, T.; Gralla, R.; Hainsworth, J.; Kris, M.; Anthony, L.; Khovasteh, A.; Tapazoglou, E.; Benedict, C.; Hahne, W. Double blind randomized comparison of the antiemetic efficacy of intravenous dolasetron and intravenous ondansetron in the prevention of acute cisplatin induced emesis in patients with cancer. J. Clin. Oncol. 1996, 14, 2242-2249.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 2242-2249
    • Hesketh, P.1    Navari, R.M.2    Grote, T.3    Gralla, R.4    Hainsworth, J.5    Kris, M.6    Anthony, L.7    Khovasteh, A.8    Tapazoglou, E.9    Benedict, C.10    Hahne, W.11
  • 10
    • 0028888664 scopus 로고
    • Dexamethasone, granisetron, or both for the prevention of nausea and vomiting during chemotherapy for cancer
    • The Italian Group for Antiemetic Research. Dexamethasone, granisetron, or both for the prevention of nausea and vomiting during chemotherapy for cancer. N. Engl. J. Med. 1995, 332, 1-5.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1-5
  • 11
    • 0028274981 scopus 로고
    • A randomized double blind comparison of intravenous ondansetron alone and in combination with intravenous dexamethasone in the prevention of high dose cisplatin induced emesis
    • Hesketh, P.J.; Harvey, W.H.; Harker, W.G.; Beck, T.M.; Ryan, T.; Bricker, L.J.; Kishja, J.A.; Murphy, W.K.; Hainsworth, J.D.; Haley, B. A randomized double blind comparison of intravenous ondansetron alone and in combination with intravenous dexamethasone in the prevention of high dose cisplatin induced emesis. J. Clin. Oncol. 1994, 12, 596-600.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 596-600
    • Hesketh, P.J.1    Harvey, W.H.2    Harker, W.G.3    Beck, T.M.4    Ryan, T.5    Bricker, L.J.6    Kishja, J.A.7    Murphy, W.K.8    Hainsworth, J.D.9    Haley, B.10
  • 14
    • 0031712820 scopus 로고    scopus 로고
    • Double blind dose finding study of four intravenous doses of dexamethasone in the prevention of cisplatin induced acute emesis
    • Italian Group for Antiemetic Research. Double blind dose finding study of four intravenous doses of dexamethasone in the prevention of cisplatin induced acute emesis. J. Clin. Oncol. 1998, 16, 2937-2942.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 2937-2942
  • 15
    • 0030847832 scopus 로고    scopus 로고
    • Oral ondansetron 8 mg twice daily is as effective as 8 mg three times daily in the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy
    • Beck, T.M.; York, M.; Chang, A.; Navari, R.M.; Harvey, W.H.; Meshad, M.; Griffin, D.; Wenta, A. Oral ondansetron 8 mg twice daily is as effective as 8 mg three times daily in the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy. Cancer Investig. 1997, 15, 297-303.
    • (1997) Cancer Investig. , vol.15 , pp. 297-303
    • Beck, T.M.1    York, M.2    Chang, A.3    Navari, R.M.4    Harvey, W.H.5    Meshad, M.6    Griffin, D.7    Wenta, A.8
  • 16
    • 0028218986 scopus 로고
    • Effect of schedule and maintenance on the antiemetic efficacy of ondansetron combined with dexamethasone in acute and delayed nausea and emesis in patients receiving moderately emetogenic chemotherapy: A phase III trial by the National Cancer Institute of Canada clinical trials group
    • Kaizer, L.; Warr, D.; Hoskins, P.; Latreille, J.; Lofters, W.; Yau, J.; Palmer, M.; Zee, B.; Levy, M.; Pater, J. Effect of schedule and maintenance on the antiemetic efficacy of ondansetron combined with dexamethasone in acute and delayed nausea and emesis in patients receiving moderately emetogenic chemotherapy: a phase III trial by the National Cancer Institute of Canada clinical trials group. J. Clin. Oncol. 1994, 12, 1050-1057.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 1050-1057
    • Kaizer, L.1    Warr, D.2    Hoskins, P.3    Latreille, J.4    Lofters, W.5    Yau, J.6    Palmer, M.7    Zee, B.8    Levy, M.9    Pater, J.10
  • 17
    • 0029102865 scopus 로고
    • Oral ondansetron for the control of cisplatin-induced delayed emesis: A large, multicenter, double-blind, randomized comparative trial of ondansetron versus placebo
    • Navari, R.M.; Madajcwicz, S.; Anderson, N.; Tchekmedyian, N.S.; Whaley, W.; Garewal, H.; Beck, T.M.; Chang, A.Y.; Greenberg, B.; Caldwell, K.C. Oral ondansetron for the control of cisplatin-induced delayed emesis: a large, multicenter, double-blind, randomized comparative trial of ondansetron versus placebo. J. Clin. Oncol. 1995, 13, 2408-2416.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 2408-2416
    • Navari, R.M.1    Madajcwicz, S.2    Anderson, N.3    Tchekmedyian, N.S.4    Whaley, W.5    Garewal, H.6    Beck, T.M.7    Chang, A.Y.8    Greenberg, B.9    Caldwell, K.C.10
  • 18
    • 0031691344 scopus 로고    scopus 로고
    • Antiemetic Subcommittee of the Multinational Association of Supportive Care in Cancer: Prevention of chemotherapy and radiotherapy-induced emesis: Results of perugia consensus conference
    • Antiemetic Subcommittee of the Multinational Association of Supportive Care in Cancer: prevention of chemotherapy and radiotherapy-induced emesis: results of perugia consensus conference. Ann. Oncol. 1998, 9, 811-819.
    • (1998) Ann. Oncol. , vol.9 , pp. 811-819
  • 20
    • 0343183307 scopus 로고    scopus 로고
    • Dexamethasone alone or in combination with ondansetron for the prevention of delayed nausea and vomiting induced by chemotherapy
    • The Italian Group for Antiemetic Research. Dexamethasone alone or in combination with ondansetron for the prevention of delayed nausea and vomiting induced by chemotherapy. N. Engl. J. Med. 2000, 342, 1554-1559.
    • (2000) N. Engl. J. Med. , vol.342 , pp. 1554-1559
  • 21
    • 0024515648 scopus 로고
    • Controlling delayed vomiting: Double blind, randomized trial comparing placebo, dexamethasone alone, and metoclopramide plus dexamethasone in patients receiving cisplatin
    • Kris, M.G.; Gralla, R.J.; Tyson, L.B. Controlling delayed vomiting: double blind, randomized trial comparing placebo, dexamethasone alone, and metoclopramide plus dexamethasone in patients receiving cisplatin. J. Clin. Oncol. 1989, 7, 108-114.
    • (1989) J. Clin. Oncol. , vol.7 , pp. 108-114
    • Kris, M.G.1    Gralla, R.J.2    Tyson, L.B.3
  • 22
    • 0031026404 scopus 로고    scopus 로고
    • Ondansetron versus metoclopramide, both combined with dexamethasone, in the prevention of cisplatin induced delayed emesis
    • Italian Group for Antiemetic Research. Ondansetron versus metoclopramide, both combined with dexamethasone, in the prevention of cisplatin induced delayed emesis. J. Clin. Oncol. 1997, 15, 124-130.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 124-130
  • 23
    • 0028819975 scopus 로고
    • Oral granisetron with or without methylprednisolone versus metoclopramide plus methylprednisolone in the management of delayed nausea and vomiting induced by cisplatin-based chemotherapy
    • Gebbis, V.; Testa, A.; Valenza, R.; Cannata, G.; Tirrito, M.L.; Gabbia, N. Oral granisetron with or without methylprednisolone versus metoclopramide plus methylprednisolone in the management of delayed nausea and vomiting induced by cisplatin-based chemotherapy. Cancer 1995, 76, 1821-1828.
    • (1995) Cancer , vol.76 , pp. 1821-1828
    • Gebbis, V.1    Testa, A.2    Valenza, R.3    Cannata, G.4    Tirrito, M.L.5    Gabbia, N.6
  • 25
    • 0030034135 scopus 로고    scopus 로고
    • Role of maintenance oral dexamethasone in prophylaxis of delayed emesis caused by moderately emetogenic chemotherapy
    • Koo, W.O.; Ang, P.T. Role of maintenance oral dexamethasone in prophylaxis of delayed emesis caused by moderately emetogenic chemotherapy. Ann. Oncol. 1996, 7, 71-74.
    • (1996) Ann. Oncol. , vol.7 , pp. 71-74
    • Koo, W.O.1    Ang, P.T.2
  • 26
    • 0028218986 scopus 로고
    • Effect of schedule and maintenance on the antiemetic efficacy of ondansetron combined with dexamethasone in acute and delayed nausea and emesis in patients receiving moderately emetogenic chemotherapy: A phase III trial by the National Cancer Institute of Canada trials group
    • Kaizer, L.; Warr, D.; Hoskins, P.; Latreille, J.; Lofters, W.; Yau, J.; Palmer, M.; Zie, B.; Levy, M.; Pater, J. Effect of schedule and maintenance on the antiemetic efficacy of ondansetron combined with dexamethasone in acute and delayed nausea and emesis in patients receiving moderately emetogenic chemotherapy: a phase III trial by the National Cancer Institute of Canada trials group. J. Clin. Oncol. 1994, 12, 1050-1057.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 1050-1057
    • Kaizer, L.1    Warr, D.2    Hoskins, P.3    Latreille, J.4    Lofters, W.5    Yau, J.6    Palmer, M.7    Zie, B.8    Levy, M.9    Pater, J.10
  • 27
    • 0020696529 scopus 로고
    • Neuropharmacology of chemotherapy-induced emesis
    • Borison, H.L.; McCarthy, L.E. Neuropharmacology of chemotherapy-induced emesis. Drugs 1983, 25 (Suppl 1), 8-17.
    • (1983) Drugs , vol.25 , Issue.SUPPL. 1 , pp. 8-17
    • Borison, H.L.1    McCarthy, L.E.2
  • 30
    • 0027381126 scopus 로고
    • Anti-emetic profile of a non-peptide neurokinin NK-1 receptor antagonist, CP-99,994, in ferrets
    • Bountra, C.; Bruce, K.; Dale, T.; Garner, C.; Jordan, C.T.; Wissel, D.; Ward, P. Anti-emetic profile of a non-peptide neurokinin NK-1 receptor antagonist, CP-99,994, in ferrets. Eur. J. Pharmacol. 1993, 249, R3-R4.
    • (1993) Eur. J. Pharmacol. , vol.249
    • Bountra, C.1    Bruce, K.2    Dale, T.3    Garner, C.4    Jordan, C.T.5    Wissel, D.6    Ward, P.7
  • 34
    • 0029893106 scopus 로고    scopus 로고
    • Broad spectrum antiemetic effects of CP-122,721, a tachykinin NK-1 receptor antagonist in ferrets
    • Gonsalves, S.; Watson, J.; Ashron, C. Broad spectrum antiemetic effects of CP-122,721, a tachykinin NK-1 receptor antagonist in ferrets. Eur. J. Pharmacol. 1996, 305, 181-185.
    • (1996) Eur. J. Pharmacol. , vol.305 , pp. 181-185
    • Gonsalves, S.1    Watson, J.2    Ashron, C.3
  • 41
    • 0037403701 scopus 로고    scopus 로고
    • Establishing the dose of the oral NK-1 antagonist aprepitant for chemotherapy induced nausea and vomiting
    • Chawla, S.P.; Grunberg, S.M.; Gralla, R.J.; et al. Establishing the dose of the oral NK-1 antagonist aprepitant for chemotherapy induced nausea and vomiting. Cancer 2003, 97, 2290-2300.
    • (2003) Cancer , vol.97 , pp. 2290-2300
    • Chawla, S.P.1    Grunberg, S.M.2    Gralla, R.J.3
  • 42
    • 0347816226 scopus 로고    scopus 로고
    • The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting: A multinational, randomized, double-blind placebo-controlled trial in patients receiving high-dose cisplatin-the aprepitant protocol 052 study group
    • Hesketh, P.J.; Grunberg, S.M.; Gralla, R.J.; et al. The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting: a multinational, randomized, double-blind placebo-controlled trial in patients receiving high-dose cisplatin-the aprepitant protocol 052 study group. J. Clin. Oncol. 2003, 21, 4112-4119.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 4112-4119
    • Hesketh, P.J.1    Grunberg, S.M.2    Gralla, R.J.3
  • 43
    • 0038728753 scopus 로고    scopus 로고
    • Addition of the neurokinin-1 receptor antagonist aprepitant to standard antiemetic therapy improves control of chemotherapy-induced nausea and vomiting
    • Poli-Bigelli, S.; Rodrigues-Pereira, J.; Carides, A.D.; et al. Addition of the neurokinin-1 receptor antagonist aprepitant to standard antiemetic therapy improves control of chemotherapy-induced nausea and vomiting. Cancer 2003, 97, 3090-3098.
    • (2003) Cancer , vol.97 , pp. 3090-3098
    • Poli-Bigelli, S.1    Rodrigues-Pereira, J.2    Carides, A.D.3
  • 44
    • 0346556083 scopus 로고    scopus 로고
    • Addition of the oral NK1 antagonist aprepitant to standard antiemetics provides protection against nausea and vomiting during multiple cycles of cisplatin-based chemotherapy
    • deWitt, R.; Herrstedt, J.; Rapoport, B.L.; et al. Addition of the oral NK1 antagonist aprepitant to standard antiemetics provides protection against nausea and vomiting during multiple cycles of cisplatin-based chemotherapy. J. Clin. Oncol. 2003, 21, 4105-4111.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 4105-4111
    • DeWitt, R.1    Herrstedt, J.2    Rapoport, B.L.3
  • 45
    • 1642513757 scopus 로고    scopus 로고
    • The oral NK-1 antagonist, aprepitant, given with standard antiemetics provides protection against nausea and vomiting over multiple cycles of cisplatin-based chemotherapy: A combined analysis of two randomized, placebo-controlled phase III clinical trials
    • deWitt, R.; Herrstedt, J.; Rapoport, B.; et al. The oral NK-1 antagonist, aprepitant, given with standard antiemetics provides protection against nausea and vomiting over multiple cycles of cisplatin-based chemotherapy: a combined analysis of two randomized, placebo-controlled phase III clinical trials. European. J. Cancer. 2004, 40, 403-410.
    • (2004) European. J. Cancer , vol.40 , pp. 403-410
    • DeWitt, R.1    Herrstedt, J.2    Rapoport, B.3
  • 46
    • 5444271770 scopus 로고    scopus 로고
    • Phase III double-blind study to assess an aprepitant-containing regimen for the prevention of nausea and vomiting due to moderately emetogenic chemotherapy
    • Abstract 8007
    • Warr, D.G.; Eisenberg, P.; Hesketh, P.J.; et al. Phase III double-blind study to assess an aprepitant-containing regimen for the prevention of nausea and vomiting due to moderately emetogenic chemotherapy. Proc. Am. Soc. Clin. Oncol. 2004, Abstract 8007.
    • (2004) Proc. Am. Soc. Clin. Oncol.
    • Warr, D.G.1    Eisenberg, P.2    Hesketh, P.J.3


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