Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume

Molecular Psychiatry

Volumn 7, Issue 9, 2002, Pages 933-941

  Van der Hart, M G C ^a   Czeh B ^a   De Biurrun, G ^a   Michaelis, T ^b   Watanabe, T ^b   Natt, O ^b   Frahm, J ^b   Fuchs, E ^a  

^a GERMAN PRIMATE CENTER   (Germany)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

Depression; Hippocampus; Neurogenesis; Proton magnetic resonance spectroscopy; Substance P; Tree shrew

Indexed keywords

5 [[2 [1 [3,5 BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY] 3 (4 FLUOROPHENYL) 4 MORPHOLINYL]METHYL] N,N DIMETHYL 1H 1,2,3 TRIAZOLE 4 METHANAMINE; ANTIDEPRESSANT AGENT; CLOMIPRAMINE; INOSITOL; N ACETYLASPARTIC ACID; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; SUBSTANCE P; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN METABOLISM; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; DEPRESSION; DRUG EFFICACY; GRANULE CELL; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; MALE; MENTAL STRESS; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIMATE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PSYCHOSOCIAL DISORDER;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BODY WEIGHT; BRAIN CHEMISTRY; CELL DIVISION; CHRONIC DISEASE; CLOMIPRAMINE; DENTATE GYRUS; DEPRESSIVE DISORDER, MAJOR; DISEASE MODELS, ANIMAL; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RECEPTORS, NEUROKININ-1; STRESS, PSYCHOLOGICAL; TUPAIIDAE;

EID: 0036428828     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4001130     Document Type: Article

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