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Volumn 91, Issue 5, 2004, Pages 1945-1954

Characterization of Wide Dynamic Range Neurons in the Deep Dorsal Horn of the Spinal Cord in Preprotachykinin-A Null Mice in Vivo

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; NEUROKININ A; PREPROTACHYKININ; PREPROTACHYKININ A; SUBSTANCE P; UNCLASSIFIED DRUG;

EID: 16544367329     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00945.2003     Document Type: Article
Times cited : (19)

References (69)
  • 1
    • 0030798999 scopus 로고    scopus 로고
    • Inflammation increases the distribution of dorsal horn neurons that internalize the neurokinin-1 receptor in response to noxious and non-noxious stimulation
    • Abbadie C, Trafton J, Liu H, Mantyh PW, and Basbaum AI. Inflammation increases the distribution of dorsal horn neurons that internalize the neurokinin-1 receptor in response to noxious and non-noxious stimulation. J Neurosci 17: 8049-8060, 1997.
    • (1997) J Neurosci , vol.17 , pp. 8049-8060
    • Abbadie, C.1    Trafton, J.2    Liu, H.3    Mantyh, P.W.4    Basbaum, A.I.5
  • 3
    • 0032917013 scopus 로고    scopus 로고
    • Spinal mechanisms of acute and persistent pain
    • Basbaum AI. Spinal mechanisms of acute and persistent pain. Reg Anesth Pain Med 24: 59-67, 1999.
    • (1999) Reg Anesth Pain Med , vol.24 , pp. 59-67
    • Basbaum, A.I.1
  • 4
    • 0023895875 scopus 로고
    • A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
    • Bennett GJ and Xie YK. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33: 87-107, 1988.
    • (1988) Pain , vol.33 , pp. 87-107
    • Bennett, G.J.1    Xie, Y.K.2
  • 5
    • 0033056376 scopus 로고    scopus 로고
    • Actions of intrathecal diphtheria toxin-substance P fusion protein on models of persistent pain
    • Benoliel R, Eliav E, Mannes AJ, Caudle RM, Leeman S, and Iadarola MJ. Actions of intrathecal diphtheria toxin-substance P fusion protein on models of persistent pain. Pain 79: 243-253, 1999.
    • (1999) Pain , vol.79 , pp. 243-253
    • Benoliel, R.1    Eliav, E.2    Mannes, A.J.3    Caudle, R.M.4    Leeman, S.5    Iadarola, M.J.6
  • 6
    • 0014609028 scopus 로고
    • Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli
    • Bessou P and Perl ER. Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli. J Neurophysiol 32: 1025-1043, 1969.
    • (1969) J Neurophysiol , vol.32 , pp. 1025-1043
    • Bessou, P.1    Perl, E.R.2
  • 7
    • 0030961297 scopus 로고    scopus 로고
    • Interaction between neurons in different laminae of the dorsal horn of the spinal cord. A correlation study in normal and neuropathic rats
    • Biella G, Riva L, and Sotgiu ML. Interaction between neurons in different laminae of the dorsal horn of the spinal cord. A correlation study in normal and neuropathic rats. Eur J Neurosci 9: 1017-1025, 1997.
    • (1997) Eur J Neurosci , vol.9 , pp. 1017-1025
    • Biella, G.1    Riva, L.2    Sotgiu, M.L.3
  • 8
    • 0028999428 scopus 로고
    • Morphological characterization of substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis
    • Brown JL, Liu H, Maggio JE, Vigna SR, Mantyh PW, and Basbaum AI. Morphological characterization of substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis. J Comp Neurol 356: 327-344, 1995.
    • (1995) J Comp Neurol , vol.356 , pp. 327-344
    • Brown, J.L.1    Liu, H.2    Maggio, J.E.3    Vigna, S.R.4    Mantyh, P.W.5    Basbaum, A.I.6
  • 9
    • 0029989646 scopus 로고    scopus 로고
    • Role of substance P in the modulation of C-fiber-evoked responses of spinal dorsal horn neurons
    • Budai D and Larson AA. Role of substance P in the modulation of C-fiber-evoked responses of spinal dorsal horn neurons. Brain Res 710: 197-203, 1996.
    • (1996) Brain Res , vol.710 , pp. 197-203
    • Budai, D.1    Larson, A.A.2
  • 10
  • 11
    • 0027481908 scopus 로고
    • Wide dynamic range but not nociceptive-specific neurons encode multidimensional features of prolonged repetitive heat pain
    • Coghill RC, Mayer DJ, and Price DD. Wide dynamic range but not nociceptive-specific neurons encode multidimensional features of prolonged repetitive heat pain. J Neurophysiol 69: 703-716, 1993.
    • (1993) J Neurophysiol , vol.69 , pp. 703-716
    • Coghill, R.C.1    Mayer, D.J.2    Price, D.D.3
  • 12
    • 0026077953 scopus 로고
    • Spatial distribution of nociceptive processing in the rat spinal cord
    • Coghill RC, Price DD, Hayes RL, and Mayer DJ. Spatial distribution of nociceptive processing in the rat spinal cord. J Neurophysiol 65: 133-140, 1991.
    • (1991) J Neurophysiol , vol.65 , pp. 133-140
    • Coghill, R.C.1    Price, D.D.2    Hayes, R.L.3    Mayer, D.J.4
  • 13
    • 0023588142 scopus 로고
    • Intrathecal administration of substance P in the rat: Spinal transection or morphine blocks the behavioural responses but not the facilitation of the tail flick reflex
    • Cridland RA and Henry JL. Intrathecal administration of substance P in the rat: spinal transection or morphine blocks the behavioural responses but not the facilitation of the tail flick reflex. Neurosci Lett 84: 203-208, 1988.
    • (1988) Neurosci Lett , vol.84 , pp. 203-208
    • Cridland, R.A.1    Henry, J.L.2
  • 14
    • 0029161130 scopus 로고
    • Modulation of excitatory amino acid responses by tachykinins and selective tachykinin receptor agonists in the rat spinal cord
    • Cumherhatch MJ, Chizh BA, and Headley PM. Modulation of excitatory amino acid responses by tachykinins and selective tachykinin receptor agonists in the rat spinal cord. Br J Pharmacol 115: 1005-1012, 1995.
    • (1995) Br J Pharmacol , vol.115 , pp. 1005-1012
    • Cumherhatch, M.J.1    Chizh, B.A.2    Headley, P.M.3
  • 16
    • 0026333731 scopus 로고
    • Substance P-mediated slow excitatory postsynaptic potential elicited in dorsal horn neurons in vivo by noxious stimulation
    • De Koninck Y and Henry JL. Substance P-mediated slow excitatory postsynaptic potential elicited in dorsal horn neurons in vivo by noxious stimulation. Proc Natl Acad Sci USA 88: 11344-11348, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 11344-11348
    • De Koninck, Y.1    Henry, J.L.2
  • 17
    • 0030582659 scopus 로고    scopus 로고
    • Thermal hyperalgesia in rat evoked by intrathecal substance P at multiple stimulus intensities reflects an increase in the gain of nociceptive processing
    • Dirig DM and Yaksh TL. Thermal hyperalgesia in rat evoked by intrathecal substance P at multiple stimulus intensities reflects an increase in the gain of nociceptive processing. Neurosci Lett 220: 93-96, 1996.
    • (1996) Neurosci Lett , vol.220 , pp. 93-96
    • Dirig, D.M.1    Yaksh, T.L.2
  • 18
    • 0027217498 scopus 로고
    • Combined application of excitatory amino acids and substance P produces long-lasting changes in responses of primate spinothalamic tract neurons
    • Dougherty PM, Palecek J, Zorn S, and Willis WD. Combined application of excitatory amino acids and substance P produces long-lasting changes in responses of primate spinothalamic tract neurons. Brain Res Brain Res Rev 18: 227-246, 1993.
    • (1993) Brain Res Brain Res Rev , vol.18 , pp. 227-246
    • Dougherty, P.M.1    Palecek, J.2    Zorn, S.3    Willis, W.D.4
  • 19
    • 0033104153 scopus 로고    scopus 로고
    • Substance P receptor (neurokinin-1)-expressing neurons in lamina I of the spinal cord encode for the intensity of noxious stimulation: A c-Fos study in rat
    • Doyle CA and Hunt SP. Substance P receptor (neurokinin-1)-expressing neurons in lamina I of the spinal cord encode for the intensity of noxious stimulation: a c-Fos study in rat. Neuroscience 89: 17-28, 1999.
    • (1999) Neuroscience , vol.89 , pp. 17-28
    • Doyle, C.A.1    Hunt, S.P.2
  • 20
    • 0023950602 scopus 로고
    • Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat
    • Duggan AW, Hendry IA, Morton CR, Hutchison WD, and Zhao ZQ. Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat. Brain Res 451: 261-273, 1988.
    • (1988) Brain Res , vol.451 , pp. 261-273
    • Duggan, A.W.1    Hendry, I.A.2    Morton, C.R.3    Hutchison, W.D.4    Zhao, Z.Q.5
  • 21
    • 0023711158 scopus 로고
    • Is substance P a primary afferent neurotransmitter for nociceptive input? I. Analysis of pain-related behaviors resulting from intrathecal administration of substance P and 6 excitatory compounds
    • Frenk H, Bossut D, Urca G, and Mayer DJ. Is substance P a primary afferent neurotransmitter for nociceptive input? I. Analysis of pain-related behaviors resulting from intrathecal administration of substance P and 6 excitatory compounds. Brain Res 455: 223-231, 1988.
    • (1988) Brain Res , vol.455 , pp. 223-231
    • Frenk, H.1    Bossut, D.2    Urca, G.3    Mayer, D.J.4
  • 22
    • 0017181611 scopus 로고
    • Effects of substance P on functionally identified units in cat spinal cord
    • Henry JL. Effects of substance P on functionally identified units in cat spinal cord. Brain Res 114: 439-451, 1976.
    • (1976) Brain Res , vol.114 , pp. 439-451
    • Henry, J.L.1
  • 23
    • 0034214841 scopus 로고    scopus 로고
    • NK1 (substance P) receptor antagonists-why are they not analgesic in humans?
    • Hill R. NK1 (substance P) receptor antagonists-why are they not analgesic in humans? Trends Pharmacol Sci 21: 244-246, 2000.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 244-246
    • Hill, R.1
  • 24
    • 0016717712 scopus 로고
    • Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neurons
    • Hokfelt T, Kellerth JO, Nilsson G, and Pernow B. Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neurons. Brain Res 100: 235-252, 1975.
    • (1975) Brain Res , vol.100 , pp. 235-252
    • Hokfelt, T.1    Kellerth, J.O.2    Nilsson, G.3    Pernow, B.4
  • 25
    • 0029005024 scopus 로고
    • Central versus peripheral site of action of the tachykinin NK1-antagonist RP 67580 in inhibiting chemonociception
    • Holzer-Petsche U and Rordorf-Nikolic T. Central versus peripheral site of action of the tachykinin NK1-antagonist RP 67580 in inhibiting chemonociception. Br J Pharmacol 115: 486-490, 1995.
    • (1995) Br J Pharmacol , vol.115 , pp. 486-490
    • Holzer-Petsche, U.1    Rordorf-Nikolic, T.2
  • 26
    • 0019507468 scopus 로고
    • Intrathecal substance P elicits a caudally-directed biting and scratching behavior in mice
    • Hylden JL and Wilcox GL. Intrathecal substance P elicits a caudally-directed biting and scratching behavior in mice. Brain Res 217: 212-215, 1981.
    • (1981) Brain Res , vol.217 , pp. 212-215
    • Hylden, J.L.1    Wilcox, G.L.2
  • 27
    • 0030963836 scopus 로고    scopus 로고
    • Mechanism of mustard oil-induced skin inflammation in mice
    • Inoue H, Asaka T, Nagata N, and Koshihara Y. Mechanism of mustard oil-induced skin inflammation in mice. Eur J Pharmacol 333: 231-240, 1997.
    • (1997) Eur J Pharmacol , vol.333 , pp. 231-240
    • Inoue, H.1    Asaka, T.2    Nagata, N.3    Koshihara, Y.4
  • 28
    • 0030612063 scopus 로고    scopus 로고
    • Spinal NK2 receptors contribute to the increased excitability of the nociceptive flexor reflex during persistent peripheral inflammation
    • Jia YP and Seybold VS. Spinal NK2 receptors contribute to the increased excitability of the nociceptive flexor reflex during persistent peripheral inflammation. Brain Res 751: 169-174, 1997.
    • (1997) Brain Res , vol.751 , pp. 169-174
    • Jia, Y.P.1    Seybold, V.S.2
  • 29
    • 0037109674 scopus 로고    scopus 로고
    • Spinal neurons that possess the substance P receptor are required for the development of central sensitization
    • Khasabov SG, Rogers SD, Ghilardi JR, Peters CM, Mantyh PW, and Simone DA. Spinal neurons that possess the substance P receptor are required for the development of central sensitization. J Neurosci 22: 9086-9098, 2002.
    • (2002) J Neurosci , vol.22 , pp. 9086-9098
    • Khasabov, S.G.1    Rogers, S.D.2    Ghilardi, J.R.3    Peters, C.M.4    Mantyh, P.W.5    Simone, D.A.6
  • 30
    • 0030882629 scopus 로고    scopus 로고
    • Profile of neuronal excitation following selective activation of the neurokinin-1 receptor in rat deep dorsal horn in vitro
    • King AE, Ackley MA, and Slack JR. Profile of neuronal excitation following selective activation of the neurokinin-1 receptor in rat deep dorsal horn in vitro. Brain Res 767: 55-63, 1997a.
    • (1997) Brain Res , vol.767 , pp. 55-63
    • King, A.E.1    Ackley, M.A.2    Slack, J.R.3
  • 31
    • 0030949195 scopus 로고    scopus 로고
    • Tachykinin actions on deep dorsal horn neurons in vitro: An electrophysiological and morphological study in the immature rat
    • King AE, Slack JR, Lopez-Garcia JA, and Ackley MA. Tachykinin actions on deep dorsal horn neurons in vitro: an electrophysiological and morphological study in the immature rat. Eur J Neurosci 9: 1037-1046, 1997b.
    • (1997) Eur J Neurosci , vol.9 , pp. 1037-1046
    • King, A.E.1    Slack, J.R.2    Lopez-Garcia, J.A.3    Ackley, M.A.4
  • 32
    • 0024337784 scopus 로고
    • Stimulus specificity of peripherally evoked substance P release from the rabbit dorsal horn in situ
    • Kuraishi Y, Hirota N, Sato Y, Hanashima N, Takagi H, and Satoh M. Stimulus specificity of peripherally evoked substance P release from the rabbit dorsal horn in situ. Neuroscience 30: 241-250, 1989.
    • (1989) Neuroscience , vol.30 , pp. 241-250
    • Kuraishi, Y.1    Hirota, N.2    Sato, Y.3    Hanashima, N.4    Takagi, H.5    Satoh, M.6
  • 33
    • 0034036363 scopus 로고    scopus 로고
    • Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene
    • Laird JM, Olivar T, Roza C, De Felipe C, Hunt SP, and Cervero F. Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene. Neuroscience 98: 345-352, 2000.
    • (2000) Neuroscience , vol.98 , pp. 345-352
    • Laird, J.M.1    Olivar, T.2    Roza, C.3    De Felipe, C.4    Hunt, S.P.5    Cervero, F.6
  • 34
    • 0035252574 scopus 로고    scopus 로고
    • Role of central and peripheral tachykinin NK1 receptors in capsaicin-induced pain and hyperalgesia in mice
    • Laird JM, Roza C, De Felipe C, Hunt SP, and Cervero F. Role of central and peripheral tachykinin NK1 receptors in capsaicin-induced pain and hyperalgesia in mice. Pain 90: 97-103, 2001.
    • (2001) Pain , vol.90 , pp. 97-103
    • Laird, J.M.1    Roza, C.2    De Felipe, C.3    Hunt, S.P.4    Cervero, F.5
  • 35
    • 0027225257 scopus 로고
    • Peptides and the primary afferent nociceptor
    • Levine JD, Fields HL, and Basbaum AI. Peptides and the primary afferent nociceptor. J Neurosci 13: 2273-2286, 1993.
    • (1993) J Neurosci , vol.13 , pp. 2273-2286
    • Levine, J.D.1    Fields, H.L.2    Basbaum, A.I.3
  • 36
    • 0029012284 scopus 로고
    • The types of neuron in spinal dorsal horn which possess neurokinin-1 receptors
    • Littlewood NK, Todd AJ, Spike RC, Watt C, and Shehah SA. The types of neuron in spinal dorsal horn which possess neurokinin-1 receptors. Neuroscience 66: 597-608, 1995.
    • (1995) Neuroscience , vol.66 , pp. 597-608
    • Littlewood, N.K.1    Todd, A.J.2    Spike, R.C.3    Watt, C.4    Shehah, S.A.5
  • 37
    • 0034007744 scopus 로고    scopus 로고
    • Nerve injury-induced mechanical but not thermal hyperalgesia is attenuated in neurokinin-1 receptor knockout mice
    • Mansikka H, Sheth RN, DeVries C, Lee H, Winchurch R, and Raja SN. Nerve injury-induced mechanical but not thermal hyperalgesia is attenuated in neurokinin-1 receptor knockout mice. Exp Neurol 162: 343-349, 2000.
    • (2000) Exp Neurol , vol.162 , pp. 343-349
    • Mansikka, H.1    Sheth, R.N.2    DeVries, C.3    Lee, H.4    Winchurch, R.5    Raja, S.N.6
  • 40
    • 0035878076 scopus 로고    scopus 로고
    • PKCgamma contributes to a subset of the NMDA-dependent spinal circuits that underlie injury-induced persistent pain
    • Martin WJ, Malmherg AB, and Basbaum AI. PKCgamma contributes to a subset of the NMDA-dependent spinal circuits that underlie injury-induced persistent pain. J Neurosci 21: 5321-5327, 2001.
    • (2001) J Neurosci , vol.21 , pp. 5321-5327
    • Martin, W.J.1    Malmherg, A.B.2    Basbaum, A.I.3
  • 41
    • 0034720177 scopus 로고    scopus 로고
    • Allodynia and hyperalgesia evoked by sciatic mononeuropathy in NK1 receptor knockout mice
    • Martinez-Caro L and Laird JM. Allodynia and hyperalgesia evoked by sciatic mononeuropathy in NK1 receptor knockout mice. Neuroreport 11: 1213-1217, 2000.
    • (2000) Neuroreport , vol.11 , pp. 1213-1217
    • Martinez-Caro, L.1    Laird, J.M.2
  • 42
    • 0026333437 scopus 로고
    • Release of substance P into the superficial dorsal horn following nociceptive activation of the hindpaw of the rat
    • McCarson KE and Goldstein BD. Release of substance P into the superficial dorsal horn following nociceptive activation of the hindpaw of the rat. Brain Res 568: 109-115, 1991.
    • (1991) Brain Res , vol.568 , pp. 109-115
    • McCarson, K.E.1    Goldstein, B.D.2
  • 43
    • 0017344097 scopus 로고
    • An analysis of response properties of spinal cord dorsal horn neurones to nonnoxious and noxious stimuli in the spinal rat
    • Menetrey D, Giesler GJ Jr, and Besson JM. An analysis of response properties of spinal cord dorsal horn neurones to nonnoxious and noxious stimuli in the spinal rat. Exp Brain Res 27: 15-33, 1977.
    • (1977) Exp Brain Res , vol.27 , pp. 15-33
    • Menetrey, D.1    Giesler Jr., G.J.2    Besson, J.M.3
  • 45
    • 0027435390 scopus 로고
    • The effects of neurokinin receptor antagonists on mustard oil-evoked activation of rat dorsal horn neurons
    • Munro FE, Fleetwood-Walker SM, Parker RM, and Mitchell R. The effects of neurokinin receptor antagonists on mustard oil-evoked activation of rat dorsal horn neurons. Neuropeptides 25: 299-305, 1993.
    • (1993) Neuropeptides , vol.25 , pp. 299-305
    • Munro, F.E.1    Fleetwood-Walker, S.M.2    Parker, R.M.3    Mitchell, R.4
  • 46
    • 0028173330 scopus 로고
    • NK1 and NK2 receptors contribute to C-fibre evoked slow potentials in the spinal cord
    • Nagy I, Miller BA, and Woolf CJ. NK1 and NK2 receptors contribute to C-fibre evoked slow potentials in the spinal cord. Neuroreport 5: 2105-2108, 1994.
    • (1994) Neuroreport , vol.5 , pp. 2105-2108
    • Nagy, I.1    Miller, B.A.2    Woolf, C.J.3
  • 47
    • 0029954092 scopus 로고    scopus 로고
    • Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons
    • Neumann S, Doubell TP, Leslie T, and Woolf CJ. Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons. Nature 384: 360-364, 1996.
    • (1996) Nature , vol.384 , pp. 360-364
    • Neumann, S.1    Doubell, T.P.2    Leslie, T.3    Woolf, C.J.4
  • 49
    • 0026751792 scopus 로고
    • Responses of spinothalamic tract cells to mechanical and thermal stimulation of skin in rats with experimental peripheral neuropathy
    • Palecek J, Paleckova V, Dougherty PM, Carlton SM, and Willis WD. Responses of spinothalamic tract cells to mechanical and thermal stimulation of skin in rats with experimental peripheral neuropathy. J Neurophysiol 67: 1562-1573, 1992.
    • (1992) J Neurophysiol , vol.67 , pp. 1562-1573
    • Palecek, J.1    Paleckova, V.2    Dougherty, P.M.3    Carlton, S.M.4    Willis, W.D.5
  • 50
    • 0027330263 scopus 로고
    • Inhibition by NK2 but not NK1 antagonists of carrageenan-induced preprodynorphin mRNA expression in rat dorsal horn lamina I neurons
    • Parker RM, Fleetwood-Walker SM, Rosie R, Munro FE, and Mitchell R. Inhibition by NK2 but not NK1 antagonists of carrageenan-induced preprodynorphin mRNA expression in rat dorsal horn lamina I neurons. Neuropeptides 25: 213-222, 1993.
    • (1993) Neuropeptides , vol.25 , pp. 213-222
    • Parker, R.M.1    Fleetwood-Walker, S.M.2    Rosie, R.3    Munro, F.E.4    Mitchell, R.5
  • 51
    • 0034625658 scopus 로고    scopus 로고
    • Psychological and neural mechanisms of the affective dimension of pain
    • Price DD. Psychological and neural mechanisms of the affective dimension of pain. Science 288: 1769-1772, 2000.
    • (2000) Science , vol.288 , pp. 1769-1772
    • Price, D.D.1
  • 52
    • 0033120641 scopus 로고    scopus 로고
    • The induction and potentiation of c-Jun and c-Fos expression in spinal neurons mediated by NK1 and NK2 receptors
    • Redburn JL and Leah JD. The induction and potentiation of c-Jun and c-Fos expression in spinal neurons mediated by NK1 and NK2 receptors. Neuropeptides 33: 115-119, 1999.
    • (1999) Neuropeptides , vol.33 , pp. 115-119
    • Redburn, J.L.1    Leah, J.D.2
  • 53
    • 0022524574 scopus 로고
    • Does neurogenic inflammation alter the sensitivity of unmyelinated nociceptors in the rat?
    • Reeh PW, Kocher L, and Jung S. Does neurogenic inflammation alter the sensitivity of unmyelinated nociceptors in the rat? Brain Res 384: 42-50, 1986.
    • (1986) Brain Res , vol.384 , pp. 42-50
    • Reeh, P.W.1    Kocher, L.2    Jung, S.3
  • 54
    • 0029076797 scopus 로고
    • Antinociceptive profiles of non-peptidergic neurokinin1 and neurokinin2 receptor antagonists: A comparison to other classes of antinociceptive agent
    • Seguin L, Le Marouille-Girardon S, and Millan MJ. Antinociceptive profiles of non-peptidergic neurokinin1 and neurokinin2 receptor antagonists: a comparison to other classes of antinociceptive agent. Pain 61: 325-343, 1995.
    • (1995) Pain , vol.61 , pp. 325-343
    • Seguin, L.1    Le Marouille-Girardon, S.2    Millan, M.J.3
  • 56
    • 0030890339 scopus 로고    scopus 로고
    • Differential roles of neurokinin 1 and neurokinin 2 receptors in the development and maintenance of heat hyperalgesia induced by acute inflammation
    • Sluka KA, Milton MA, Willis WD, and Westlund KN. Differential roles of neurokinin 1 and neurokinin 2 receptors in the development and maintenance of heat hyperalgesia induced by acute inflammation. Br J Pharmacol 120: 1263-1273, 1997.
    • (1997) Br J Pharmacol , vol.120 , pp. 1263-1273
    • Sluka, K.A.1    Milton, M.A.2    Willis, W.D.3    Westlund, K.N.4
  • 57
    • 0028597002 scopus 로고
    • Non-specific effects of the tachykinin NK1 receptor antagonist, CP-99,994, in antinociceptive tests in rat, mouse and gerbil
    • Smith G, Harrison S, Bowers J, Wiseman J, and Birch P. Non-specific effects of the tachykinin NK1 receptor antagonist, CP-99,994, in antinociceptive tests in rat, mouse and gerbil. Eur J Pharmacol 271: 481-487, 1994.
    • (1994) Eur J Pharmacol , vol.271 , pp. 481-487
    • Smith, G.1    Harrison, S.2    Bowers, J.3    Wiseman, J.4    Birch, P.5
  • 58
    • 0028989395 scopus 로고
    • Poststimulus afterdischarges of spinal WDR and NS units in rats with chronic nerve constriction
    • Sotgiu ML, Biella G, and Riva L. Poststimulus afterdischarges of spinal WDR and NS units in rats with chronic nerve constriction. Neuroreport 6: 1021-1024, 1995.
    • (1995) Neuroreport , vol.6 , pp. 1021-1024
    • Sotgiu, M.L.1    Biella, G.2    Riva, L.3
  • 59
    • 0242543184 scopus 로고    scopus 로고
    • The coding of noxious mechanical and thermal stimuli of deep dorsal horn neurones is attenuated in NK1 knockout mice
    • Suzuki R, Hunt SP, and Dickenson AH. The coding of noxious mechanical and thermal stimuli of deep dorsal horn neurones is attenuated in NK1 knockout mice. Neuropharmacology 45: 1093-1100, 2003.
    • (2003) Neuropharmacology , vol.45 , pp. 1093-1100
    • Suzuki, R.1    Hunt, S.P.2    Dickenson, A.H.3
  • 60
    • 0025267304 scopus 로고
    • Differential release of substance P and somatostatin in the rat spinal cord in response to noxious cold and heat; effect of dynorphin A(1-17)
    • Tiseo PJ, Adler MW, and Liu-Chen LY. Differential release of substance P and somatostatin in the rat spinal cord in response to noxious cold and heat; effect of dynorphin A(1-17). J Pharmacol Exp Ther 252: 539-545, 1990.
    • (1990) J Pharmacol Exp Ther , vol.252 , pp. 539-545
    • Tiseo, P.J.1    Adler, M.W.2    Liu-Chen, L.Y.3
  • 61
    • 0027234727 scopus 로고
    • The inhibitory effect of substance P antagonist, CP-96, 345, on the late discharges of nociceptive neurons in the rat superficial spinal dorsal horn
    • Toda T and Hayashi H. The inhibitory effect of substance P antagonist, CP-96,345, on the late discharges of nociceptive neurons in the rat superficial spinal dorsal horn. Neurosci Lett 158: 36-38, 1993.
    • (1993) Neurosci Lett , vol.158 , pp. 36-38
    • Toda, T.1    Hayashi, H.2
  • 62
    • 0035873496 scopus 로고    scopus 로고
    • Differential contribution of substance P and neurokinin A to spinal cord neurokinin-1 receptor signaling in the rat
    • Trafton JA, Abbadie C, and Basbaum AI. Differential contribution of substance P and neurokinin A to spinal cord neurokinin-1 receptor signaling in the rat. J Neurosci 21: 3656-3664, 2001.
    • (2001) J Neurosci , vol.21 , pp. 3656-3664
    • Trafton, J.A.1    Abbadie, C.2    Basbaum, A.I.3
  • 63
    • 0027933184 scopus 로고
    • Modulation of spinal excitability: Co-operation between neurokinin and excitatory amino acid neurotransmitters
    • Urban L, Thompson SW, and Dray A. Modulation of spinal excitability: co-operation between neurokinin and excitatory amino acid neurotransmitters. Trends Neurosci 17: 432-438, 1994.
    • (1994) Trends Neurosci , vol.17 , pp. 432-438
    • Urban, L.1    Thompson, S.W.2    Dray, A.3
  • 64
    • 0034988626 scopus 로고    scopus 로고
    • Sensory processing in the deep spinal dorsal horn of neurokinin-1 receptor knockout mice
    • Weng HR, Mansikka H, Winchurch R, Raja SN, and Dougherty PM. Sensory processing in the deep spinal dorsal horn of neurokinin-1 receptor knockout mice. Anesthesiology 94: 1105-1112, 2001.
    • (2001) Anesthesiology , vol.94 , pp. 1105-1112
    • Weng, H.R.1    Mansikka, H.2    Winchurch, R.3    Raja, S.N.4    Dougherty, P.M.5
  • 65
    • 0026472539 scopus 로고
    • Spinal substance P and N-methyl-D-aspartate receptors are coactivated in the induction of central sensitization of the nociceptive flexor reflex
    • Xu XJ, Dalsgaard CJ, and Wiesenfeld-Hallin Z. Spinal substance P and N-methyl-D-aspartate receptors are coactivated in the induction of central sensitization of the nociceptive flexor reflex. Neuroscience 51: 641-648, 1992.
    • (1992) Neuroscience , vol.51 , pp. 641-648
    • Xu, X.J.1    Dalsgaard, C.J.2    Wiesenfeld-Hallin, Z.3
  • 66
    • 0019314381 scopus 로고
    • Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo
    • Yaksh TL, Jessell TM, Gamse R, Mudge AW, and Leeman SE. Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo. Nature 286: 155-157, 1980.
    • (1980) Nature , vol.286 , pp. 155-157
    • Yaksh, T.L.1    Jessell, T.M.2    Gamse, R.3    Mudge, A.W.4    Leeman, S.E.5
  • 67
    • 0025092248 scopus 로고
    • Quantitative autoradiographic distribution of multiple neurokinin binding sites in rat spinal cord
    • Yashpal K, Dam TV, and Quirion R. Quantitative autoradiographic distribution of multiple neurokinin binding sites in rat spinal cord. Brain Res 506: 259-266, 1990.
    • (1990) Brain Res , vol.506 , pp. 259-266
    • Yashpal, K.1    Dam, T.V.2    Quirion, R.3
  • 69
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals [editorial]. Pain 16: 109-110, 1983.
    • (1983) Pain , vol.16 , pp. 109-110
    • Zimmermann, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.