Indexed keywords
NEUROKININ 1 RECEPTOR ANTAGONIST;
TACHYKININ RECEPTOR ANTAGONIST;
3 (2 METHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE;
3-(2-METHOXYBENZYLAMINO)-2-PHENYLPIPERIDINE;
APREPITANT;
MORPHOLINE DERIVATIVE;
NEUROKININ 1 RECEPTOR;
PIPERIDINE DERIVATIVE;
ANALGESIA;
DRUG POTENCY;
DRUG USE;
HUMAN;
LETTER;
NONHUMAN;
PAIN;
PRIORITY JOURNAL;
TREATMENT FAILURE;
ANIMAL;
CLINICAL TRIAL;
DISEASE MODEL;
DRUG ANTAGONISM;
STEREOISOMERISM;
ANIMALS;
CLINICAL TRIALS;
DISEASE MODELS, ANIMAL;
HUMANS;
MORPHOLINES;
PAIN;
PIPERIDINES;
RECEPTORS, NEUROKININ-1;
STEREOISOMERISM;
1
0034214841
NK1 (substance P) receptor antagonists – why are they not analgesic in humans?
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Discrepant results from preclinical and clinical studies on the potential of substance P–receptor antagonist compounds as analgesics
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3
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Clinical analgesic trials of NK1 antagonists
R.A. Dionne Clinical analgesic trials of NK1 antagonists Curr. Opin. CPNS Drugs 1 1999 82 85
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Dionne, R.A.1
5
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Investigation into species variation in tachykinin NK1-receptors by the use of the non-peptide antagonist, CP-96,345
1-receptors by the use of the non-peptide antagonist, CP-96,345 Br. J. Pharmacol. 104 1991 292 293
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Beresford, I.J.M.1
6
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Selective neurokinin-1 antagonists are anti-hyperalgesic in a model of neuropathic pain in the guinea-pig
E.A. Campbell Selective neurokinin-1 antagonists are anti-hyperalgesic in a model of neuropathic pain in the guinea-pig Neuroscience 87 1998 527 532
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Neuroscience , vol.87
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Campbell, E.A.1
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Oral anti-hyperalgesic and anti-inflammatory activity of NK1 receptor antagonsits in models of inflammatory hyperalgesia in the guinea-pig
1 receptor antagonsits in models of inflammatory hyperalgesia in the guinea-pig Pain 87 2000 253 264
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Lanepitant, an NK-1 antagonist, in painful diabetic neuropathy
D.J. Goldstein O. Wang Lanepitant, an NK-1 antagonist, in painful diabetic neuropathy Clin. Pharmacol. Ther. 65 1999 119
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Clin. Pharmacol. Ther. , vol.65
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Goldstein, D.J.1
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9
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PET imaging of NK1 receptors in living human brain
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Hietala, J.1
10
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The substance P receptor antagonist CP-99,994 reduces acute postoperative pain
R.A. Dionne The substance P receptor antagonist CP-99,994 reduces acute postoperative pain Clin. Pharmacol. Ther. 64 1998 562 568
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Clin. Pharmacol. Ther. , vol.64
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Dionne, R.A.1
11
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Comparison of a neurokinin-1 antagonist, L-754-030, to placebo, acetaminophen and ibuprofen in the dental pain model
R.R. Reinhardt Comparison of a neurokinin-1 antagonist, L-754-030, to placebo, acetaminophen and ibuprofen in the dental pain model Clin. Pharmacol. Ther. 63 1998 168
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Clin. Pharmacol. Ther. , vol.63
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Reinhardt, R.R.1
12
0038596547
The substance P receptor antagonist L-754-030 (MK-0869) is ineffective in the treatment of postherpetic neuralgia
G.A. Block The substance P receptor antagonist L-754-030 (MK-0869) is ineffective in the treatment of postherpetic neuralgia Neurology 50 1998 A225
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Neurology , vol.50
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Block, G.A.1
13
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Lanepitant in osteoarthritis pain
D.J. Goldstein Lanepitant in osteoarthritis pain Clin. Pharmacol. Ther. 63 1998 143
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Clin. Pharmacol. Ther. , vol.63
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Goldstein, D.J.1
14
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