The tachykinin peptide family

Pharmacological Reviews

Volumn 54, Issue 2, 2002, Pages 285-322

  Severini, Cinzia ^a   Improta, Giovanna ^b   Falconieri Erspamer, Giuliana ^b   Salvadori, Severo ^c   Erspamer, Vittorio ^b  

^a CNR   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c Ferrara   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINOVALERYLSUBSTANCE P [7-11][9 PROLINE 10 (N METHYLLEUCINE)]; BRADYKININ; CAPSAICIN; ELEDOISIN; HISTAMINE; KASSININ; NEUROKININ A; NEUROKININ B; NEUROPEPTIDE; PEPTIDE DERIVATIVE; PHYSALAEMIN; RECEPTOR SUBTYPE; SUBSTANCE P; TACHYKININ DERIVATIVE;

AMPHIBIA; DOSE RESPONSE; DRUG EFFECT; DRUG INDUCED DISEASE; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; HUMAN; MOUSE; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; REVIEW;

AMINO ACID SEQUENCE; ANIMALS; HUMANS; MOLECULAR SEQUENCE DATA; RECEPTORS, TACHYKININ; SPECIES SPECIFICITY; TACHYKININS;

EID: 0036259051     PISSN: 00316997     EISSN: None     Source Type: Journal    
DOI: 10.1124/pr.54.2.285     Document Type: Review

References (388)

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2. Occurrence and some properties of eledoisin in extracts of posterior salivary glands of Eledone
3. Isolation and amino acid sequence of physalaemin, the main active polypeptide of the skin of Physalaemus fuscomaculatus
4. Structure of uperolein, a physalaemin-like endecapeptide occurring in the skin of Uperuleia rugosa and Uperoleia marmorata
5. Occurrence of phyllomedusin, a physalaemin-like decapeptide, in the skin of Phyllomedusa bicolor
6. Amino acid composition and sequence of kassinin, a tachykinin dodecapeptide from the skin of the African frog Kassina senegalensis
7. Immunocytochemical localization of substance P and ACTH-like activity in the central nervous system of the earthworm Lumbricus terrestris L
8. Preprotachykinin gene expression in the human basal ganglia: Characterization of mRNAs and pre-mRNAs produced by alternate RNA splicing
9. Tachykinins: Local gastric effects and brainstem responses
10. Adrenergic and peptidergic (substance P and vasoactive intestinal polypeptide) innervation of the rat portal vein
11. Inhibitory effect of intracranial injections of tachykinins on angiotensin-induced drinking in the cat
12. Light and electric microscopic localization of substance P-like immunoreactivity in the cerebral ganglion of locust with a monoclonal antibody
13. The effects of eledoisin and bradykinin on the general and visceral circulation
14. Effect of the endecapeptide eledoisin on the coronary blood flow: Comparison with bradykinin, nitroglycerin and epinephrine in the dog
15. Peripheral vasodilator action of eledoisin, bradykinin and nitroglycerin in anaesthetized dogs
16. Vasodilating action of eledoisin on the intact and denervated skeletal muscle preparation of the dog
17. Immunoreactive tachykinins in 24 h collections of urine from patients with carcinoid tumours: Characterization and correlation with plasma concentrations
18. Synthetic peptides related to eledoisin
19. Peptides of amphibian skin active on the gut. Tachykinins and caeruleins. Isolation, structure and basic functions
20. Substance P
21. Occurrence of physalaemin in extracts of the skin of Physalaemus fuscomaculatus and its pharmacological actions on extravascular smooth muscle
22. Action of some natural peptides on the stomach of the anaesthetized rat
23. The effect of physalaemin and related peptides on salivary secretion
24. Enlargement of salivary glands in rats after chronic administration of physalaemin or isoprenaline
25. Effects of physalaemin on some exocrine secretions of dogs and rats
26. Portata distrettuale e metabolismo dell'encefalo sotto infusione continua di eledoisina
27. Expression of tachykinins by ileal and lung carcinoid tumors assessed by combined in situ hybridization, immunocytochemistry and radioimmunoassay
28. Sensory and autonomic innervation of non-hairy and hairy human skin. An immunohistochemical study
29. Distribution and effects of tachykinin-like peptides in the stomatogastric nervous system of the crab Cancer borealis
30. A cDNA encoding the precursor of the rat neuropeptide, neurokinin B
31. Novel uperin peptides from the dorsal glands of the Australian foodplain toadlet Uperoleia inundata
32. Chromodacryorrhoea and repetitive hind paw tapping: Models of peripheral and central tachykinin NK1 receptor activation in gerbils
33. Effect of central administration of tachykinins on thermoregulation and gastric emptying in rats
34. Central tachykinin NK3 receptors in the inhibitory action on the rat colonic propulsion of a new tachykinin PG-KII
35. Tachykinin multiplicity in rat central nervous system as studied using antisera raised against substance P and neurokinin A
36. The effects of substance P and related peptides on alpha-amylase release from rat parotid gland slices
37. Substance P effects on blood flow, fluid transport and vasoactive intestinal polypeptide release in the feline small intestine
38. Cardiovascular effects of substance P: Effects on the heart and regional blood flow in the dog
39. Immunohistochemical localization of regulatory peptides and serotonin in six species of trematode parasites
40. Effects of chronic administration of eledoisin or physalaemin on the rat salivary glands
41. Primary afferent tachykinins are required to experience moderate to ir tense pain
42. Effects of eledoisin on gastro-intestinal electrical activity
43. Determination of the amino acid residues in substance P conferring selectivity and specificity for the rat neurokinin receptors
44. Enterochromaffin cells of the digestive system: Cellular source of guanylin, a guanylate cyclase activating peptide
45. Sialokinin I and II: Vasodilatory tachykinins from the yellow fever mosquito Aedes aegypti
46. Isolation of a sialagogic peptide from bovine hypothalamic tissue and its characterization as substance P
47. Amino-acid sequence of substance P
48. Expression of the diversity of neuronal and hormonal peptides in the cleavage of precursor molecules
49. Two novel tachykinin-related peptides from the nervous system of the crab Cancer borealis
50. Stimulation of tachykinin NK3 receptors in the nucleus basalis magnocellularis reduces alcohol intake in rats
51. Characterization of an antiserum against an achetakinin I-analog and its use for the localization of culekinin depolarizing peptide II in the mosquito Culex salinarius
52. Tachykinins (substance P, neurokinin A and neuropeptide gamma) and neurotensin from the intestine of the Burmese python, Phython molurus
53. Scyliorhinin I and II, two novel tachykinins from dogfish gut
54. Measurement and partial characterization of the multiple forms of neurokinin A-like immunoreactivity in carcinoid tumours
55. 3]substance P and neurokinin A from chicken small intestine
56. Carassin: A tachykinin that is structurally related to neuropeptide-gamma from the brain of the goldfish
57. Chem and immunochemical characterization of substance P-like immunoreactivity and physalaemin-like immunoreactivity in a carcinoid tumour
58. 2] scyliorhinin II from the intestine of the ray Torpedo marmorata
59. Bufokinin: A substance P-related peptide from the gut of the toad. Bufo marinus with high binding affinity but low selectivity for mammalian tachykinin receptors
60. The regional distribution of somatostatin, substance P and neurotensin in human brain
61. Posttraining administration of substance P and its N-terminal fragment block the amnestic effects of diazepam
62. Cardiovascular effects of amphibian and mammalian tachykinins in the toad Bufo marinus
63. Carcinoid tumors: Development of our knowledge
64. Carcinoids and carcinoid syndrome
65. Guanylin: An endogenous activator of intestinal guanylate cyclase
66. Neurokinin A-like immunoreactivity in rat primary sensory neurons: Coexistence with substance P
67. Stimulation of rabbit lacrimal gland secretion with biologically active peptides
68. Azione dell'eledoisina sulla permeabilità capillare nell'uomo, nella cavia e nel ratto
69. Effetti della fisalaemina sulla secrezione lacrimale
70. The treatment of Sjoegren's syndrome with physalaemin
71. Hypotensive effect of eledoisin, physalaemin and related peptides in man
72. Dipsogenic effect of angiotensin II, bombesin and tachykinins in the duck
73. Potent dipsogenic effect of physalaemin in the pigeon
74. Tachykinins and body fluid regulation
75. Altered nociception, analgesia and aggression in mice lacking the receptor for substance P
76. Digital vascular responses to intraarterial injections of bradykinin, kallidin and eledoisin in man
77. Role of the N-terminal arginine in the histamine-releasing activity of substance P, bradykinin and related peptides
78. Peptides and histamine release from rat peritoneal mast cells
79. Intracerebroventricular injection of capsaicin and substance P provokes the micturition reflex in the rat
80. Intrathecal substance P, depresses the tail-flick response: Antagonism by naloxone
81. Intrathecal substance P depresses spinal motor and sensory responses to stimulation ofnociceptive afferents: Antagonism by naloxone
82. Different receptors are involved in the endothelium-mediated relaxation and the smooth muscle contraction of the rabbit pulmonary artery in response to substance P and related neurokinins
83. Effects of peptides and non-peptides on isolated arterial smooth muscle: Role of endothelium
84. Peptidergic control of male rat sexual behavior: The effects of intracerebral injections of substance P and cholecystokinin
85. Facilitation of lordosis by injection of substance P into the midbrain central gray
86. Infusion of substance P or neurokinin A by microdialysis alters responses of primate spinothalamic tract neurons to cutaneous stimuli and to iontophoretically released excitatory amino acids
87. Regional distribution of substance P-like immunoreactivity in the lower brainstem of the rat
88. Modulation of the immune response by tachykinins
89. Effect of substance P on resistance and capacitance vessels in the human forearm
90. Relative secretory contributions of the three major salivary glands of the rat in response to substance P and supersensitivity
91. Immunohistochemical investigations of neuropeptides in the brain, corpora cardiaca and corpora allata of an adult lepidopteran insect (Manduca sexta) L
92. Behavioural effects of tachykinins and related peptides
93. The "direct" effect of physalaemin on salivary gland cells
94. The pharmacology of salivary myoepithelial cells in dogs
95. Regional distribution of methionine-enkephalin and substance P-like immunoreactivity in normal human brain and in Huntington's disease
96. Expression of preprotachykinin-A and neuropeptide Y messenger RNA in the thymus
97. Release of histamine by substance P
98. Ricerche preliminari sulla moschatina
99. The tachykinin peptides family
100. Bioactive secretions of the integument
101. Structure and pharmacological actions of physalaemin, the main active polypeptide of the skin of Physalaemus fuscomaculatus
102. Pharmacological actions of eledoisin on extravascular smooth muscle
103. The action of eledoisin on the systemic arterial blood pressure of some experimental animals
104. Comparison of neurokinin A and substance P on cardiovascular and airway function in man
105. Peptide and acetylcholine action on neurons of the cat subfornical organ
106. Substance P and bradykinin stimulate plasma extravasation in the mouse gastrointestinal tract and pancreas
107. Localization of substance P-like, leucine-enkephalin-like, methionine-enkephalin-like, FMRFamide-like immunoreactivity in the eyestalk of the fiddler crab Uca pugilator
108. Structure/activity relationships for some substance P-related peptides that cause wheal and flare reactions in human skin
109. Dual actions of substance P on nociception: Possible role of endogenous opioids
110. Vasodilating activity of the natural polypeptide physalaemin on hind limb and coronary vascular beds of dog. Comparison with eledoisin and nitroglycerin
111. Localization of somatostatin-, substance P- and calcitonin-like immunoreactivity in the neural ganglion of Ciona intestinalis L (Ascidiaceae)
112. Substance P-, neurotensin- and bombesin-like immunoreactivities in the gill epithelium of Ciona intestinalis L
113. Gastro-intestinal and neurohormonal peptides in the alimentary tract and cerebral complex of Ciona intestinalis (Ascidiaceae)
114. Analysis of the inflammatory response induced by substance P in the mouse pleural cavity
115. Tachykinin receptors and the airways
116. An invertebrate-type tachykinin isolated from the freshwater bivalve mollusc, Anodonta cygnea
117. Role of endothelium in responses of vascular smooth muscle
118. The role of endothelium in the response of vascular smooth muscle to drugs
119. Substance P-like immunoreactivity in nerves associated with the vascular system of guinea-pigs
120. Influence of substance P and fragments on passive avoidance behavior
121. Human brain substance P: Distribution in controls and Huntington's chorea
122. The intestine as source of the immunoreactive substance P in plasma of the cat
123. Nociceptive behavior after intrathecal injections of substance P, neurokinin A and calcitonin gene-related peptide in mice
124. Substance P in tumours: Pheochromocytoma and carcinoid
125. Substance P and substance K receptor binding sites in the human gastrointestinal tract: Localization by autoradiography
126. Substance P-like immunoreactivity in capsaicinsensitive structures of the rat thymus
127. Co-localization of calcitonin gene-related peptide-like immunoreactivity with substance P in cutaneous, vascular and visceral sensory neurons of guinea pigs
128. Bronchoconstrictor action of bradykinin, kallidin and eledoisin
129. Substance P-like immunoreactivity in the stomatogastric nervous systems of the crab Cancer borealis and the lobster Panulirus interruptus and Homarus americanus
130. Characterization of antisera specific to NK1, NK2 and NK3 neurokinin receptors and their utilization to localize receptors in the rat gastrointestinal tract
131. Substance P-like immunoreactivity in the nervous system of hydra
132. Failure of substance P to produce analgesia in the mouse
133. Tachykinin receptor types: Classification and membrane signaling mechanism
134. Immunocytochemical demonstration of neuropeptides and serotonin in the nervous systems of adult Schistosoma mansoni
135. Immunocytochemical evidence for the presence of "mammalian" neurohormonal peptides in neurones of the tapeworm Diphyllobathrium dendriticum
136. Substance P, a highly active naturally occurring polypeptide
137. Flare and itch induced by substance P in human skin
138. Effects of substance P and neurokinin A (substance k) on motor behavior: Unique effect of substance P attributable to its amino-terminal sequence
139. Age and strain differences in some behavioral effects of intracranial substance P
140. The role of enzymatic processing in the biological actions of substance P
141. Modulation of isolation-induced fighting by N- and C-terminal analogs of substance P: Evidence for multiple recognition sites
142. Neurokinin A increases duodenal mucosal permeability, bicarbonate secretion and fluid output in the rat
143. Similar effects of substance P and related peptides on salivation and on phosphatidylinositol turnover in rat salivary glands
144. Substance P, the immune system and inflammation
145. Substance P enhancement of inhibitory avoidance learning: Mediation by the N-terminal sequence
146. Anxiolytic-like action of neurokinin substance P administered systematically or into the nucleus basalis magnocellularis region
147. The effect of bradykinin, kallidin and eledoisin upon the pulmonary vascular bed of an isolated blood-perfused rabbit lung preparation
148. Effects of intrathecal and intracerebroventricular injections of substance P on nociception in the rat and mouse
149. Interaction of substance P with the respiratory control system in the rat
150. The substance P(1-7) fragment is a potent modulator of substance P actions in the brain
151. Coexistence of neuronal messengers: An overview
152. Immunohistochemical distribution of substance P
153. Substance P: Localization in the central nervous system and in some primary sensory neurons
154. Anticholeretic effect of substance P in anaesthetized dogs
155. Effects of tachykinins on gastric acid and pepsin secretion and on gastric outflow in the Atlantic cod Gadus morhua
156. Stimulation and inhibition of gastrointestinal propulsion induced by substance P and substance K in the rat
157. Capsaicin: Cellular targets, mechanisms of action and selectivity for tin sensory neurons
158. Tachykinins in the gut. Part I. Expression, release and motor function
159. Tachykinins in the gut. Part II. Roles in neural excitation, secretion and inflammation
160. Tachykinin receptors in gastrointestinal motility
161. Contractile effects of substance P and neurokinin A.on the rat stomach in vivo and in vitro
162. In vivo and in vitro actions of mammalian tachykinins
163. Comparison of cardiovascular and bronchoconstrictor effects of substance P, substance K and other tachykinins
164. The regional distribution of kassininlike immunoreactivity in central and peripheral tissues of the cat
165. Intrathecal substance P elicits a caudally-directed biting and scratching behavior in mice
166. Specific binding of substance P aminoterminal heptapeptide [SP(1-7)] to mouse brain and spinal cord membranes
167. Two novel tachykinin-related neuropeptides in the echiuroid worm Urechis unicinctus
168. Action of eledoisin on human lacrimal secretion in normal and pathological conditions
169. Tachykinins: Effects on gastric secretion and emptying in rats
170. Effects of supraspinal administration of PG-SPI and PG-KII, two amphibian tachykinin peptides, on nociception in the rat
171. In vitro and in vivo biological activities of PG-KII, a novel kassinin-like peptide from the skin of the Australian frog Pseudophryne güntheri
172. Regional distribution of substance P-like immunoreactivity in the frog brain and spinal cord: Immunohistochemical analysis
173. Ontogeny of substance P-containing neuron system of the rat: Immunohistochemical analysis: I. Forebrain and upper brainstem
174. Nociceptin/orphanin FQ-induced nociceptive responses through substance P release from peripheral nerve endings in mice
175. Receptors mediating tachykinin-induced contractile responses in guinea-pig trachea
176. Substance P equals pain substance
177. Sialogogic effects on rat submandibular gland of analogs of the C-terminal hexapeptide of substance P
178. Treatment of a severe case of cheratoconjunctivitis sicca with eledoisin
179. Eledoisin: A successful therapeutic concept for filamentary keratitis
180. Direct evidence for neurogenic inflammation and its prevention by denervation and by pretreatment with capsaicin
181. Co-release of substance P and neurokinin A from the Atlantic cod stomach
182. Substance P-related and neurokinin A-related peptides from the brain of the cod and trout
183. Primary structures and effects on gastrointestinal motility of tachykinins from the rainbow trout
184. Interaction of physalaemin, substance P and eledoisin with specific membrane receptors on pancreatic acinar cells
185. The effect of tachykinins on the conducting airways of the rat
186. Neuropeptide gamma: A peptide isolated from rabbit intestine that is derived from gamma-preprotachykinin
187. Vasoactivity and immunoreactivity of fish tachykinins in the vascular system of the spiny dogfish
188. Immunochemical evidence for substance P-like peptide in tissues of the earthworm Lumbricus terrestris: Action on intestinal contraction
189. Post mortem changes and regional distribution of substance P in the rat and mouse nervous system
190. Regional distribution of substance P, neurokinin a and neurokinin β in rat central nervous system
191. Neuromedin K: A novel mammalian tachykinin identified in porcine spinal cord
192. Bradykinin as a mediator of human pain
193. Projections and actions of tachykininergic, cholinergic and serotoninergic neurones in the intestine of the Atlantic cod
194. Substance P infusion into substantia nigra of the rat: Behavioural analysis and involvement of striatal dopamine
195. Behavioural activation induced in the rat by substance P infusion into ventral tegmental area: Implication of dopaminergic A10 neurones
196. Substance P fragments and striatal endogenous dopamine outflow: Interaction with substance P
197. Amyloid β-protein activates tachykinin receptors and inositol triphosphate accumulation by synergy with glutamate
198. Novel neuropeptides, neurokinin a and b, isolated from porcine spinal cord
199. Substance P inhibits pancreatic exocrine secretion via a neural mechanism
200. The effects of substance P and other peptides on spinal neurons of the frog
201. Effect of substance P and its C-terminal hexapeptide on gastric and pancreatic secretion in the dog
202. Structure and gene organization of bovine neuromedin K precursor
203. Isolation of four novel tachykinins from frog (Rana catesbeiana) brain and intestine
204. Distinct mechanism for antidepressant activity by blockade of central substance P receptors
205. Three rat preprotachykinin mRNAs encode the neuropeptides substance P and neurokinin A
206. Action of the newly discovered mammalian tachykinins substance k and neuromedin k on gastroduodenal motility of anaesthetized dogs
207. The effects of bradykinin and eledoisin injected into the cerebral ventricles of conscious rats
208. Radioimmunoassay for the tachykinin peptide physalaemin: Detection of a physalaemin-like substance in rabbit stomach
209. Physalaemin: An amphibian tachykinin in human lung small-cell carcinoma
210. A neuropeptide in mammalian tissues with physalaemin-like immudoreactivity
211. Characterization of substance P-like immunoreactivity in submammalian species by high performance liquid chromatography
212. Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation
213. Substance P and salivary secretion
214. Sialogenic action of substance P and physalaemin-like octapeptide upon infusion into various vessels
215. Different modes of action of substance P in the motor control of the feline stomach and pylorus
216. Substance P enhances NMDA channel function in hippocampal dentate gyrus granule cells
217. Goldfish gamma-preprotachykinin mRNA encodes the neuropeptides substance P, carassin and neurokinin A
218. Regional distribution and in vivo release of tachykinin-like immunereactivities in rat brain: Evidence for regional differences in relative proportions of tachykinins
219. Identification of immunoreactive substance P in human and other mammalian endothelial cells
220. Substance P is expressed in hippocampal principal neurons during status epilepticus and plays a critical role in the maintenance of status epilepticus
221. Pharmacological and biochemical investigation of receptors for the toad and the gut tachykinin peptide bufokinin, in its species of origin
222. Immunoelectron microscopic study of substance P-containing fibers in feline cerebral arteries
223. A comparison of the effects of locally and systematically administered kinins on coronary blood flow and myocardial metabolism
224. Tachykinins increase vascular permeability in the gastrointestinal tract of the rat
225. Action of substance P on the coronary blood flow in the isolated dog heart
226. Synthesis and biological activity of a new frog skin peptide, ranamargarin
227. Effects and distribution of vagal capsaicin-sensitive substance P neurons with special reference to the trachea and lungs
228. Callitachykinin I and II, two novel myotropic peptides isolated from the blowfly Calliphora vomitoria, that have resemblances to tachykinins
229. Tachykinin NK1 receptor antagonist RP 67580 attenuates progressive hypersensitivity of flexor reflex during experimental inflammation in rats
230. Immunocytochemical demonstration of neuropeptides in the nervous system of the liver fluke Fasciola hepatica (Trematoda, Digenea)
231. The role of peptides in the regulation of the micturition reflex: An update
232. The effects of tachykinins on inflammatory and immune cells
233. Tachykinin receptors and intestinal motility
234. Tachykinin-like immunoreactivity in the mammalian urinary bladder: Correlation with the functions of the capsaicin -sensitive sensory nerves
235. Further studies on the mechanisms of the tachykinin-induced activation of micturition reflex in rats: Evidence for the involvement of capsaicin-sensitive bladder mechanoreceptors
236. The role of neuropeptides in the regulation of the micturition reflex
237. The sensory-efferent function of capsaicin-sensitive sensory neurons
238. Tachykinin receptors in the guinea-pig isolated bronchi
239. Tachykinin receptors and tachykinin receptor antagonists
240. The role of the capsaicin-sensitive innervation of the rat urinary bladder in the activation of micturition reflex
241. Activation of micturition reflex by substance P and substance K: Indirect evidence for the existence of multiple tachykinin receptors in the rat urinary bladder
242. "Kassinin" in mammals: The newest tachykinins
243. Tachykinins
244. Increased intestinal non-substance P tachykinin concentrations in malignant midgut carcinoid disease
245. Analgesic activity of substance P after intracerebral administration in rats
246. Modulation of acetylcholine metabolism in the hippocampal cholinergic pathway by intraseptally injected substance P
247. Immunocytochemical localization of enkephalin and substance P in retina and eyestalk neurones of lobster
248. Substance P-like immunoreactivity is present in the central nervous system of Limulus polyphemus
249. Activity ratio between intestinal and cardiovascular actions of caerulein and related substances in the anaesthetized dog
250. Regional differences in the motor and inflammatory responses to capsaicin in guinea pig airways. Correlation with content and release of substance P-like immunoreactivity
251. Les convertases des prohormones et systéme nerveus
252. NK1 receptors in the guinea-pig mediate locomotor hyperactivity
253. Mapping of brain sites sensitive to the antidipsogenic effect of tachykinins
254. Suppression of salt intake in the rat by neurokinin A: Comparison with the effect of kassinin
255. Inhibition of salt appetite in the rat following injection of tachykinins into the medial amygdala
256. Suppression of drinking but not feeding by central eledoisin and physalaemin in the rat
257. Effect of kassinin, neurokinin A and neurokinin B on drinking behaviour in the pigeon
258. The hypothalamic paraventricular nucleus is a site of action for the central effect of tachykinins on plasma vasopressin
259. The rat isolated portal vein: A preparation sensitive to neurokinins, particularly neurokinin B
260. Tachykinins do not cause plasma leakage in the rabbit trachea
261. Effects of tachykinins on rapidly adapting pulmonary stretch receptors and total lung resistance in anaesthetized artificially ventilated rabbits
262. The excitatory action of the newly-discovered mammalian tachykinins, neurokinin alpha and neurokinin beta, on neurones of the isolated spinal cord of the newborn rat
263. Tachykinins may modify spontaneous epileptiform activity in the rat entorhinal cortex in vitro by activating GABAergic inhibition
264. Tachykinin immunoreactivity in the parasitic flatworm Diclidophora merlangi and its fish host the whiting (Merlangius merlangus): Radioimmunoassay and chromatographic characterization using region-specific substance P and neurokinin A antisera
265. Actions of peptides isolated from amphibian skin on pancreatic acinar cells
266. The role of N-terminal tetrapeptide in the histamine-releasing action of substance P
267. Substance P-induced intestinal secretion of water and electrolytes
268. Immunomodulation by tachykinin neuropeptides
269. Comparative circulatory effects of substance P, eledoisin and physalaemin in the dog
270. Localization of neurokinin B in the central nervous system of the rat
271. N- and C-terminal substance P fragments: Differential effects on striatal (3H)substance P binding and NK1 receptor internalization
272. Tachykinins and other biologically active peptides from the skin of the Costa Rican phyllomedusid frog Agalychnis callidryas
273. Substance P-induced analgesia in the rat
274. Hyperalgesia produced by intrathecal substance P and related peptides: Desensitization and cross desensitization
275. Isolation of five tachikinin-related peptides from the midgut of the cockroach Leucophaea maderae: Existence of N-terminally extended isoforms
276. Cardiovascular roles of tachykinin peptides in the nucleus tractus solitarii of rats
277. Physalaemin- and bombesin-like peptides in the skin of the Australian leptodactylid frog Uperuleia rugosa
278. Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cyclic AMP cascades in transfected Chinese hamster ovary cells
279. Synergistic effect with Phe-Gly-Leu-Met-NH2 of the C-terminal of substance P and insulin-like growth factor-1 on epithelial wound healing of rabbit cornea
280. Synergistic effect of substance P with epidermal growth factor on epithelial migration in rabbit cornea
281. Substance P precursor and kininogen: Their structures, gene organizations and regulation
282. Studies on the cardiovascular effects of synthetic eledoisin
283. Effects of eledoisin on the systemic venous return in dogs
284. Cardiovascular effects of synthetic physalaemin
285. Tachykinin-related peptides in invertebrates: A review
286. Nucleotide sequences of cloned cDNA for two types of bovine brain substance P precursor
287. Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing
288. Identification of one tachykinin- and two kinin-related peptides in the brain of the white shrimp Penaeus vannamei
289. Distribution and constrictor effect of substance P in guinea pig tracheobronchial tissue
290. Antisera raised against eledoisin and kassinin detect elevated levels of immunoreactive materials in plasma and tumor tissues from patients with carcinoid tumors
291. Tachykinin production by carcinoid tumours in culture
292. Regional distribution of substance P, neurokinin alpha and neurokinin beta in rat spinal cord, nerve roots and dorsal root ganglia and the effects of dorsal root section or spinal transection
293. Ranakinin: A novel NK1 tachykinin receptor agonist isolated with neurokinin B from the brain of the frog Rana ridibunda
294. Tachykinins in the central and peripheral nervous system of the ascidian Ciona Intestinalis
295. The effects of eledoisin on intestinal smooth muscles of ruminants
296. The effects of some polypeptides on the systemic blood pressure of sheep
297. Neurotransmitter functions of mammalian tachykinins
298. Immunocytochemical localization of substance P in mammalian intestine
299. Centrally mediated cardiovascular and EEG responses to bradykinin and eledoisin
300. Substance P
301. Role of tachykinins in neurogenic inflammation
302. Effect of substance P on blood flow in canine adipose tissue and skeletal muscle
303. Excitation of cerebral cortical neurons by various polypeptides
304. Substance P and Hydra: An immunohistochemical and physiological study
305. The substance P receptor on rat mast cells and in human skin
306. Vasopressin release induced by intracranial injection of tachykinins is due to activation of central neurokinin-3 receptors
307. The tachykinin NK1 receptor. Part I: Ligands and mechanisms of cellular activation
308. The tachykinin NK1 receptor. Part II: Distribution and pathophysiological roles
309. Possible role(s) of neurokinins in CNS development and neurode-generative or other disorders
310. Substance P is released from the endothelium of normal and capsaicin-treated rat hind limb vasculature, in vivo, by increased flow
311. Receptors and antagonists for substance P and related peptides
312. Pharmacological receptors for substance P and neurokinins
313. Neurokinin receptor subtypes characterized by biological assays
314. Effects and interactions of sensory neuropeptides on airway microvascular leakage in guinea-pigs
315. Isolation and characterization of substance P, substance P5-11 and substance K from two metastatic ileal carcinoids
316. + efflux, amylase release and cyclic nucleotide levels in slices of rat parotid gland
317. Differential inhibition of foot tapping and chromodacryorrhoea in gerbils by CNS penetrant and non-penetrant NK1 receptor antagonists
318. Ontogeny of substance P-containing neuron system of the rat: Immunohistochemical analysis: II. Lower brain stem
319. Phosphoramidon potentiates mammalian tachykinin induced biting, licking and scratching behaviour in mice
320. N-terminal substance P fragments inhibit the spinally induced NK1 receptor mediated behavioural response in mice
321. Effects of neuropeptides and capsaicin on the canine tracheal vasculature in vivo
322. Effect of synthetic substance P on internal carotid blood flow in man
323. Evidence for substance P-immunoreactive spinal afferents that mediate bronchoconstriction
324. Intraaccumbens injections of substance P, morphine and amphetamine: Effects in conditioned place preference and behavioral activity
325. Substance P enhancement of passive and active avoidance conditioning in mice
326. Substance P facilitation of memory: Effects in an appetitively motivated learning task
327. Tachykinins stimulate release of peptide hormones (glucagon-like peptide-1 and paracrine somatostatin) and neurotransmitter (vasoactive intestinal polypeptide) from porcine ileum through NK1 receptors
328. Characterization of physalaemin -evoked rat saliva and failure of autonomic blocking agents to modify composition
329. Locustatachykinins III and IV: Two additional insect neuropeptides with homology to peptides of the vertebrate tachykinin family
330. Locustatachykinin I and II, two novel insect neuropeptides with homology to peptides of the vertebrate tachykinin family
331. Parallel bioassay of 39 tachykinins on 11 smooth muscle preparations. Structure and receptor selectivity/affinity relationship
332. Intrathecal substance P and somatostatin in rats: Behaviors indicative of sensation
333. Sensory substance P-innervation of the urinary bladder: Possible site of action of capsaicin in causing urine retention in rats
334. Bronchoconstrictor and respiratory effects of neurokinin A in dogs
335. Effects of substance P on gastric motility differ depending on the site and vagal innervation in conscious dogs
336. The endecapeptide eledoisin is a powerful vasodilating and hypotensive agent in man
337. Six novel tachykinin- and bombesin-related peptides from the skin of the Australian frog Pseudophryne guntheri
338. Substance P-like-immunoreactivity release from enterochromaffin cells of rat caecum mucosa. Inhibition by serotonin and calcium-free medium
339. Substance P-like immunoreactive neurons in the adult nervous system of the fly Sarcophaga bullata
340. Substance P in medullary carcinoma of the thyroid
341. Substance P in ovarian carcinoid
342. Human colonic substance P-producing cells are a separate population from the serotonin producing enterochromaffin cells
343. Clinical aspects of cerebral and extracerebral 5-hydroxytryptamine
344. Biliary and pancreatic secretion under the influence of substance P and a physalaemin derivative
345. Behavioural depressant and antinociceptive properties of substance P in the mouse: Possible implication of brain monoamines
346. The new enzymology of precursor processing endoproteases
347. Substance P and analgesia
348. A fragment of substance P with specific central activity: SP(1-7)
349. Substance P in the localization of a carcinoid tumor
350. Isolierung und aminosauren sequenz von substanz P aus pferdedarm
351. The effect of eledoisin on the rheogram in arteriosclerosis obliterans
352. Localization of substance P-like immunoreactivity in Hydra
353. Role of central tachykinin peptides in cardiovascular regulation in rats
354. Effect of synthetic physalaemin on splanchnic circulation in dogs
355. Modification of effects of biologically active peptides, caused by enzyme treatment, on the excitability of identifiable giant neurones of an African giant snail (Achatina fulica Férussac)
356. Inhibitory tripeptide, Lys-Phe-Tyr-, as a fragment of physalaemin
357. Effects of some oligopeptides, consisting of aromatic amino acids, on the excitability of an identifiable giant neurone of the African giant snail (Achatina fulica Férussac)
358. Effects of physalaemin, a vaso-active peptide from amphibian skin, on the excitability of an identified molluscan giant neurone of Achatina fulica Férussac
359. Differential effects of tachykinins injected intranigrally on striatal dopamine metabolism
360. Neuropeptide K: Isolation, structure and biological activities of a novel brain tachykinin
361. Neuropeptide K: A major tachykinin in plasma and tumor tissues from carcinoid patients
362. Secretory and motor effects in the submaxillary gland of the rat by intraarterial administration of some polypeptides and autonomic drugs
363. Effect of substance P on the flow of hepatic bile and pancreatic juice
364. Parasympathetic NANC-secretion of saliva in the mink and effects of substance P and VIP
365. Substance P induces a cardiovascular defense reaction in the rat: Pharmacological characterization
366. Substance P-like immunoreactivity in the central nervous system of the blattarian insect Periplaneta americana L. revealed by a monoclonal antibody
367. Cellule enterocromaffini e cellule basigranulose acidofile nei vertebrati
368. Reward for persistence in substance P research
369. Lack of beneficial effect of a tachykinin receptor antagonist in experimental colitis
370. Primary structure and receptor-binding properties of a neurokinin A-related peptide from frog gut
371. Purification and characterization of galanin and schyliorhinin I from the hybrid sturgeon Scaphirhynchus platorynchus and Scaphirhynchus albus (Acipenseriformes)
372. Structural characterization of tachykinins (neuropeptide gamma, neurokinin A and substance P) from a reptile Alligator mississipiensis
373. Tachykinins with unusual structural features from a urodele, the amphiuma, an elasmobranch, the hammerhead shark and an agnathan, the river lamprey
374. Isolation, localization and cardiovascular activity of tachykinins from the stomach of the bowfin Amia calva
375. Novel tachykinins from the brain of the sea lamprey, Petromyzon marinus and the skate, Raja rhina
376. Primary structures and biological activities of substance P-related peptides from the brain of the dogfish Scyliorhinus canicula
377. Substance P and enteroglucagon-like immunoreactivity in argentaffin and argyrophil midgut carcinoid tumours
378. Enteroglucagon and substance P-like immunoreactivity in argentaffin and argyrophil rectal carcinoids
379. Differential distribution of isoforms of Leucophaea tachykinin-related peptides (LemTRPs) in endocrine cells and neuronal processes of the cockroach midgut
380. Characterization of actions of Leucophaea tachykinin-related peptides (LemTRPs) and proctolin on cockroach hindgut contractions
381. Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo
382. Some effects of substance P on central respiratory control in rabbit pups
383. Substance P analogs: Synthesis and biological and immunological properties
384. Neurotrophic and neurotoxic effects of amyloid beta protein: Reversal by tachykinin neuropeptides
385. New tachykinins Glu2,Pro5-kassinin (Hylambates-kassinin) and hylambatin in the skin of the African rhacophorid frog Hylambates maculatus
386. Comparative toxicity of amyloid beta-peptide in neuroblastoma cell lines: Effects of albumin and physalaemin
387. Alteration in the brain content of substance P(1-7) during withdrawal in morphine-dependent rats
388. Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene