Striatal preprotachykinin gene expression reflects parkinsonian signs

NeuroReport

Volumn 15, Issue 16, 2004, Pages 2481-2484

  Wade, Timothy V ^a   Schneider, Jay S ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Cat; MPTP; mRNA; Parkinson's disease; Preprotachykinin; Striatum

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; METHAMPHETAMINE; NEUROPEPTIDE; PREPROTACHYKININ; SUBSTANCE P;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASAL GANGLION; CAT; CELL SUBPOPULATION; CONTROLLED STUDY; CORPUS STRIATUM; DENERVATION; FEMALE; GABAERGIC TRANSMISSION; GENE EXPRESSION REGULATION; GENE LOCATION; HISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MOTOR DYSFUNCTION; NONHUMAN; PARKINSONISM; PRIORITY JOURNAL; SENSORIMOTOR FUNCTION;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; BEHAVIOR, ANIMAL; CATS; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; IN SITU HYBRIDIZATION; MALE; MOTOR ACTIVITY; PARKINSONIAN DISORDERS; POSTURE; PROTEIN PRECURSORS; RADIOGRAPHY; RNA, MESSENGER; TACHYKININS; TIME FACTORS;

EID: 9644252649     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200411150-00010     Document Type: Article

References (23)

1. Gerfen CR. The neostrial mosaic: multiple levels of compartmental organization in the basal ganglia. Annu Rev Neurosci 1992; 15:285-320.
2. Herrero MT, Augood SJ, Hirsch EC, Javoy-Agid F, Luquin MR, Agid Y et al. Effects of L-Dopa on preproenkephalin and preprotachykinin gene expression in the MPTP-treated monkey striatum. Neuroscience 1995; 68:1189-1198.
3. Jolkkonen J, Jenner P and Marsden CD. L-Dopa administration differentially regulates enkephalin substance P gene expression in the caudate-putamen of MPTP-treated common marmoset. Mol Brain Res 1995; 32:297-307.
4. Morissette M, Grondin R, Goulet M, Bedard PJ and Di Paolo T. Differential regulation of striatal preproenkephalin and preprotachykinin mRNA levels in MPTP-lesioned monkeys chronically treated with dopamine D-1 or D-2 receptor agonists. J Neurochem 1999; 72:682-692.
5. Aubert I, Ghrayeb I, Normand E and Bloch B. Phenotypical characterization of the neurons expressing the D1 and D2 dopamine receptors in the monkey striatum. J Comp Neurol 2000; 418:22-32.
6. Gerfen CR, Engber TM, Mahan LC, Susel A, Chase TN, Monsma FJ Jr, and Sibley DR. D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons. Science 1990; 250:1429-1432.
7. Zeng BY, Jolkkonen J, Jenner P and Marsden CD. Chronic L-Dopa treatment differentially regulates gene expression of glumate decarboxylase, preproenkephalin and preprotachykinin in the striatum of 6-hydroxydopamine- lesioned rat. Neuroscience 1995; 66:19-28.
8. Wade TV and Schneider JS. Expression of striatal preprotachykinin mRNA in symptomatic and asymptomatic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- exposed monkeys is related to parkinsonian motor signs. J Neurosci 2001; 21:4901-4907.
9. Zhang Y, Landas K, Mueller H and Angulo JA. Progressive augmentation of striatal and accumbal preprotachykinin mRNA levels by chronic treatment with methamphetamine and effect of concurrent administration of N-methyl-D-asparate receptor antagonist MK-801. Neuropharmacology 1997; 36:325-334.
10. Schneider JS, Yuwiler A and Markham CH. Production of a parkinson-like syndrome in the cat with N-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine (MPTP): behavior, histology and biochemistry. Exp Neurol 1986; 91:293-307.
11. Schneider JS and Rothblat DS. Neurochemical evaluation of the striatum in symptomatic and recovered MPTP-treated cats. Neuroscience 1991; 44:421-429.
12. Rothblat DS and Schneider JS. Spontaneous functional recovery from parkinsonism is not due to reinnervation of the dorsal striatum by residual dopaminergic neurons. Brain Res Bull 1994; 34:309-312.
13. Frohna PA, Rothblat DS, Joyce JN and Schneider JS. Alterations in dopamine uptake sites and D1 and D2 receptors in cats symptomatic for and recovered from experimental parkinsonism. Synapse 1995; 19:46-55.
14. Schneider JS, Decamp E and Wade T. Striatal preproenkephalin gene expression is upregulated in acute but not chronic parkinsonian monkeys: implications for the contribution of the indirect striatopallidal circuit to parkinsonian symptomatology. J Neurosci 1999; 19:6643-6649.
15. Harmar AJ, Armstrong A, Pascall JC, Chapman K, Rosie R, Curtis A et al. cDNA sequence of human beta-preprotachykinin, the common precursor to substance P and neurokinin-A. FEBS Let 1986; 208:67-72.
16. Berman AJ and Jones EG. The Brain Stem of the Cat: A Cytoarchitectonic Atlas with Stereotaxic Coordinates. Madison, WI: University of Wisconsin Press; 1982.
17. Rothblat DS, Schroeder JA and Schneider JS. Tyrosine hydroxylase and dopamine transporter expression in residual dopaminergic neurons: potential contributors to spontaneous recovery from experimental Parkinsonism. J Neurosci Res 2001; 65:254-266.
18. Schroeder JA and Schneider JS. Striatal enkephalin gene expression does not reflect parkinsonian signs. Neuroreport 2000; 11:1799-1802.
19. Walker PD, Riley LA, Hart RP and Jonakait GM. Serotonin regulation of tachykinin biosynthesis in the rat neostriatum. Brain Res 1991; 546:33-39.
20. Gresch PJ and Walker PD. Serotonin-2 receptor stimulation normalizes striatal preprotachykinin messanger RNA in an animal model of Parkinson's disease. Neuroscience 1999; 93:831-841.
21. Basura GJ and Walker PD. Serotonin 2A receptor regulation of striatal neuropeptide gene expression is selective for tachykinin, but not enkephalin neurons following dopamine depletion. Mol Brain Res 2001; 92:66-77.
22. Perez-Otano I, Herrero MT, Oset C, De Caballos ML, Luquin MR, Obeso JA, Del Rio R. Extensive loss of brain dopamine and serotonin induced by chronic administration of MPTP in the marmoset. Brain Res 1991; 567:127-132.
23. Pifl C, Schingnitz G and Hornykiewics O. Effects of 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine on the regional distribution of brain monoamines in the rhesus monkey. Neuroscience 1991; 44:591-605.