-
1
-
-
0028868139
-
Host-directed and immune-based therapies for human immunodeficiency virus infection
-
Lederman MM. Host-directed and immune-based therapies for human immunodeficiency virus infection. Ann Intern Med. 1995;122:218-222.
-
(1995)
Ann Intern Med
, vol.122
, pp. 218-222
-
-
Lederman, M.M.1
-
2
-
-
23844558948
-
Tumour necrosis factor inhibitors
-
Nash PT, Florin TH. Tumour necrosis factor inhibitors. Med J Aust. 2005;183:205-208.
-
(2005)
Med J Aust
, vol.183
, pp. 205-208
-
-
Nash, P.T.1
Florin, T.H.2
-
3
-
-
21644468434
-
The evolving clinical profile of abatacept (CTLA4-Ig): A novel co-stimulatory modulator for the treatment of rheumatoid arthritis
-
Ruderman EM, Pope RM. The evolving clinical profile of abatacept (CTLA4-Ig): a novel co-stimulatory modulator for the treatment of rheumatoid arthritis. Arthritis Res Ther. 2005;7(suppl 2):S21-S25.
-
(2005)
Arthritis Res Ther
, vol.7
, Issue.2 SUPPL.
-
-
Ruderman, E.M.1
Pope, R.M.2
-
4
-
-
33744762212
-
Biological therapies directed against cells in autoimmune disease
-
Hasler P. Biological therapies directed against cells in autoimmune disease. Springer Semin Immunopathol. 2006;27:443-456.
-
(2006)
Springer Semin Immunopathol
, vol.27
, pp. 443-456
-
-
Hasler, P.1
-
5
-
-
0037413467
-
A controlled trial of natalizumab for relapsing multiple sclerosis
-
Miller DH, Khan OA, Sheremata WA, et al. A controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med. 2003;348:15-23.
-
(2003)
N Engl J Med
, vol.348
, pp. 15-23
-
-
Miller, D.H.1
Khan, O.A.2
Sheremata, W.A.3
-
6
-
-
33646696885
-
Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and metaanalysis of rare harmful effects in randomized controlled trials
-
Bongartz T, Sutton AJ, Sweeting MJ, Buchan I, Matteson EL, Montori V. Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and metaanalysis of rare harmful effects in randomized controlled trials. JAMA. 2006;295:2275-2285.
-
(2006)
JAMA
, vol.295
, pp. 2275-2285
-
-
Bongartz, T.1
Sutton, A.J.2
Sweeting, M.J.3
Buchan, I.4
Matteson, E.L.5
Montori, V.6
-
7
-
-
33644605483
-
Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy
-
Yousry TA, Major EO, Ryschkewitsch C, et al. Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy. N Engl J Med. 2006;354:924-933.
-
(2006)
N Engl J Med
, vol.354
, pp. 924-933
-
-
Yousry, T.A.1
Major, E.O.2
Ryschkewitsch, C.3
-
8
-
-
11144270580
-
Chemokines
-
Paul WE, ed. Philadelphia, Pa: Lippincott Williams & Wilkins
-
Murphy PM. Chemokines. In: Paul WE, ed. Fundamental Immunology. 5th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2003:801-840.
-
(2003)
Fundamental Immunology. 5th Ed.
, pp. 801-840
-
-
Murphy, P.M.1
-
9
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski K, Kumasaka T, Hori T, et al. Crystal structure of rhodopsin: a G protein-coupled receptor. Science. 2000;289:739-745.
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
-
10
-
-
0033523018
-
Naturally occurring CCR5 extracellular and transmembrane domain variants affect HIV-1 co-receptor and ligand binding function
-
Howard OM, Shirakawa AK, Turpin JA, et al. Naturally occurring CCR5 extracellular and transmembrane domain variants affect HIV-1 co-receptor and ligand binding function. J Biol Chem. 1999;274:16228-16234.
-
(1999)
J Biol Chem
, vol.274
, pp. 16228-16234
-
-
Howard, O.M.1
Shirakawa, A.K.2
Turpin, J.A.3
-
11
-
-
4444246007
-
Chemokine receptor CCR5: Insights into structure, function, and regulation
-
Oppermann M. Chemokine receptor CCR5: insights into structure, function, and regulation. Cell Signal. 2004;16:1201-1210.
-
(2004)
Cell Signal
, vol.16
, pp. 1201-1210
-
-
Oppermann, M.1
-
12
-
-
0030812438
-
Molecular mechanism of desensitization of the chemokine receptor CCR-5: Receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptor
-
Aramori I, Ferguson SS, Bieniasz PD, Zhang J, Cullen B, Cullen MG. Molecular mechanism of desensitization of the chemokine receptor CCR-5: receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptor. EMBO J. 1997;16:4606-4616.
-
(1997)
EMBO J
, vol.16
, pp. 4606-4616
-
-
Aramori, I.1
Ferguson, S.S.2
Bieniasz, P.D.3
Zhang, J.4
Cullen, B.5
Cullen, M.G.6
-
13
-
-
0032188973
-
Chemokine receptor CCR5 functionally couples to inhibitory G proteins and undergoes desensitization
-
Zhao J, Ma L, Wu YL, Wang P, Hu W, Pei G. Chemokine receptor CCR5 functionally couples to inhibitory G proteins and undergoes desensitization. J Cell Biochem. 1998;71:36-45.
-
(1998)
J Cell Biochem
, vol.71
, pp. 36-45
-
-
Zhao, J.1
Ma, L.2
Wu, Y.L.3
Wang, P.4
Hu, W.5
Pei, G.6
-
14
-
-
0032522970
-
Macrophage inflammatory protein-1β induces migration and activation of human thymocytes
-
Dairaghi DJ, Franz-Bacon K, Callas E, et al. Macrophage inflammatory protein-1β induces migration and activation of human thymocytes. Blood. 1998;91:2905-2913.
-
(1998)
Blood
, vol.91
, pp. 2905-2913
-
-
Dairaghi, D.J.1
Franz-Bacon, K.2
Callas, E.3
-
15
-
-
0035892099
-
HIV-1 gp120 and chemokine activation of Pyk2 and mitogen-activated protein kinases in primary macrophages mediated by calcium-dependent, pertussis toxininsensitive chemokine receptor signaling
-
Del Corno M, Liu QH, Schols D, et al. HIV-1 gp120 and chemokine activation of Pyk2 and mitogen-activated protein kinases in primary macrophages mediated by calcium-dependent, pertussis toxininsensitive chemokine receptor signaling. Blood. 2001;98:2909-2916.
-
(2001)
Blood
, vol.98
, pp. 2909-2916
-
-
Del Corno, M.1
Liu, Q.H.2
Schols, D.3
-
16
-
-
17644402459
-
Transduction of receptor signals by β-arrestins
-
Lefkowitz RJ, Shenoy SK. Transduction of receptor signals by β-arrestins. Science. 2005;308:512-517.
-
(2005)
Science
, vol.308
, pp. 512-517
-
-
Lefkowitz, R.J.1
Shenoy, S.K.2
-
18
-
-
0033567969
-
CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist
-
Blanpain C, Migeotte I, Lee B, et al. CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist. Blood. 1999;94:1899-1905.
-
(1999)
Blood
, vol.94
, pp. 1899-1905
-
-
Blanpain, C.1
Migeotte, I.2
Lee, B.3
-
19
-
-
0036467505
-
The role of chemokines in linking innate and adaptive immunity
-
Luster AD. The role of chemokines in linking innate and adaptive immunity. Curr Opin Immunol. 2002;14:129-135.
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 129-135
-
-
Luster, A.D.1
-
20
-
-
0035260758
-
Chemokines as regulators of T cell differentiation
-
Luther SA, Cyster JG. Chemokines as regulators of T cell differentiation. Nat Immunol. 2001;2:102-107.
-
(2001)
Nat Immunol
, vol.2
, pp. 102-107
-
-
Luther, S.A.1
Cyster, J.G.2
-
21
-
-
0032193205
-
Roles of chemokines and receptor polarization in NKtarget cell interactions
-
Nieto M, Navarro F, Perez-Villar JJ, et al. Roles of chemokines and receptor polarization in NKtarget cell interactions. J Immunol. 1998;161:3330-3339.
-
(1998)
J Immunol
, vol.161
, pp. 3330-3339
-
-
Nieto, M.1
Navarro, F.2
Perez-Villar, J.J.3
-
22
-
-
22244448718
-
Regulation of protein function by glycosaminoglycans-as exemplified by chemokines
-
Handel TM, Johnson Z, Crown SE, Lau EK, Proudfoot AE. Regulation of protein function by glycosaminoglycans-as exemplified by chemokines. Annu Rev Biochem. 2005;74:385-410.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 385-410
-
-
Handel, T.M.1
Johnson, Z.2
Crown, S.E.3
Lau, E.K.4
Proudfoot, A.E.5
-
23
-
-
0032904627
-
Mechanisms that regulate the function of the selectins and their ligands
-
Vestweber D, Blanks JE. Mechanisms that regulate the function of the selectins and their ligands. Physiol Rev. 1999;79:181-213.
-
(1999)
Physiol Rev
, vol.79
, pp. 181-213
-
-
Vestweber, D.1
Blanks, J.E.2
-
24
-
-
0037300378
-
Chemokines: Attractive mediators of the immune response
-
Wong MM, Fish EN. Chemokines: attractive mediators of the immune response. Semin Immunol. 2003;15:5-14.
-
(2003)
Semin Immunol
, vol.15
, pp. 5-14
-
-
Wong, M.M.1
Fish, E.N.2
-
25
-
-
18244389686
-
T cell costimulation by chemokine receptors
-
Molon B, Gri G, Bettella M, et al. T cell costimulation by chemokine receptors. Nat Immunol. 2005;6:465-471.
-
(2005)
Nat Immunol
, vol.6
, pp. 465-471
-
-
Molon, B.1
Gri, G.2
Bettella, M.3
-
26
-
-
0021751840
-
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus
-
Dalgleish AG, Beverley PC, Clapham PR, Crawford DH, Greaves MF, Weiss RA. The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature. 1984;312:763-767.
-
(1984)
Nature
, vol.312
, pp. 763-767
-
-
Dalgleish, A.G.1
Beverley, P.C.2
Clapham, P.R.3
Crawford, D.H.4
Greaves, M.F.5
Weiss, R.A.6
-
27
-
-
0026017498
-
Glycosylphosphatidylinositol-anchored CD4/Thy-1 chimeric molecules serve as human immunodeficiency virus receptors in human, but not mouse, cells and are modulated by gangliosides
-
Jasin M, Page KA, Littman DR. Glycosylphosphatidylinositol-anchored CD4/Thy-1 chimeric molecules serve as human immunodeficiency virus receptors in human, but not mouse, cells and are modulated by gangliosides. J Virol. 1991;65:440-444.
-
(1991)
J Virol
, vol.65
, pp. 440-444
-
-
Jasin, M.1
Page, K.A.2
Littman, D.R.3
-
28
-
-
0024544365
-
Human immunodeficiency virus infection studied in CD4-expressing human-murine T-cell hybrids
-
Tersmette M, van Dongen JJ, Clapham PR, et al. Human immunodeficiency virus infection studied in CD4-expressing human-murine T-cell hybrids. Virology. 1989;168:267-273.
-
(1989)
Virology
, vol.168
, pp. 267-273
-
-
Tersmette, M.1
Van Dongen, J.J.2
Clapham, P.R.3
-
29
-
-
0025797437
-
Human genes other than CD4 facilitate HIV-1 infection of murine cells
-
Weiner DB, Huebner K, Williams WV, Greene MI. Human genes other than CD4 facilitate HIV-1 infection of murine cells. Pathobiology. 1991;59:361-371.
-
(1991)
Pathobiology
, vol.59
, pp. 361-371
-
-
Weiner, D.B.1
Huebner, K.2
Williams, W.V.3
Greene, M.I.4
-
30
-
-
0029417004
-
Identification of RANTES, MIP-1α, and MIP-1β as the major HIV-suppressive factors produced by CD8+ T cells
-
Cocchi F, DeVico AL, Garzino DA, Arya SK, Gallo RC, Lusso P. Identification of RANTES, MIP-1α, and MIP-1β as the major HIV-suppressive factors produced by CD8+ T cells. Science. 1995;270:1811-1815.
-
(1995)
Science
, vol.270
, pp. 1811-1815
-
-
Cocchi, F.1
DeVico, A.L.2
Garzino, D.A.3
Arya, S.K.4
Gallo, R.C.5
Lusso, P.6
-
31
-
-
0030018156
-
CC CKR5: A RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1
-
Alkhatib G, Combadiere C, Broder CC, et al. CC CKR5: a RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1. Science. 1996;272:1955-1958.
-
(1996)
Science
, vol.272
, pp. 1955-1958
-
-
Alkhatib, G.1
Combadiere, C.2
Broder, C.C.3
-
33
-
-
0029775576
-
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
-
Bleul CC, Farzan M, Choe H, et al. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature. 1996;382:829-833.
-
(1996)
Nature
, vol.382
, pp. 829-833
-
-
Bleul, C.C.1
Farzan, M.2
Choe, H.3
-
34
-
-
0005014748
-
The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
-
Choe H, Farzan M, Sun Y, et al. The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell. 1996;85:1135-1148.
-
(1996)
Cell
, vol.85
, pp. 1135-1148
-
-
Choe, H.1
Farzan, M.2
Sun, Y.3
-
35
-
-
15844419153
-
Identification of a major co-receptor for primary isolates of HIV-1
-
Deng H, Liu R, Ellmeier W, et al. Identification of a major co-receptor for primary isolates of HIV-1. Nature. 1996;381:661-666.
-
(1996)
Nature
, vol.381
, pp. 661-666
-
-
Deng, H.1
Liu, R.2
Ellmeier, W.3
-
36
-
-
15844389650
-
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
-
Dragic T, Litwin V, Allaway GP, et al. HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature. 1996;381:667-673.
-
(1996)
Nature
, vol.381
, pp. 667-673
-
-
Dragic, T.1
Litwin, V.2
Allaway, G.P.3
-
37
-
-
0030002637
-
HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
-
Feng Y, Broder CC, Kennedy PE, Berger EA. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science. 1996;272:872-877.
-
(1996)
Science
, vol.272
, pp. 872-877
-
-
Feng, Y.1
Broder, C.C.2
Kennedy, P.E.3
Berger, E.A.4
-
38
-
-
0032104378
-
G protein-coupled receptors in HIV and SIV entry: New perspectives on lentivirus-host interactions and on the utility of animal models
-
Unutmaz D, KewalRamani VN, Littman DR. G protein-coupled receptors in HIV and SIV entry: new perspectives on lentivirus-host interactions and on the utility of animal models. Semin Immunol. 1998;10:225-236.
-
(1998)
Semin Immunol
, vol.10
, pp. 225-236
-
-
Unutmaz, D.1
KewalRamani, V.N.2
Littman, D.R.3
-
39
-
-
16144365317
-
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5
-
Trkola A, Dragic T, Arthos J, et al. CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5. Nature. 1996;384:184-187.
-
(1996)
Nature
, vol.384
, pp. 184-187
-
-
Trkola, A.1
Dragic, T.2
Arthos, J.3
-
40
-
-
0032543307
-
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
-
Kwong PD, Wyatt R, Robinson J, Sweet RW, Sodroski J, Hendrickson WA. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature. 1998;393:648-659.
-
(1998)
Nature
, vol.393
, pp. 648-659
-
-
Kwong, P.D.1
Wyatt, R.2
Robinson, J.3
Sweet, R.W.4
Sodroski, J.5
Hendrickson, W.A.6
-
41
-
-
15844388931
-
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
-
Liu R, Paxton WA, Choe S, et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell. 1996;86:367-377.
-
(1996)
Cell
, vol.86
, pp. 367-377
-
-
Liu, R.1
Paxton, W.A.2
Choe, S.3
-
42
-
-
0001633495
-
Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene: Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study
-
Dean M, Carrington M, Winkler C, et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene: Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science. 1996;273:1856-1862.
-
(1996)
Science
, vol.273
, pp. 1856-1862
-
-
Dean, M.1
Carrington, M.2
Winkler, C.3
-
43
-
-
17344372255
-
Dating the origin of the CCR5-Δ32 AIDS-resistance allele by the coalescence of haplotypes
-
Stephens JC, Reich DE, Goldstein DB, et al. Dating the origin of the CCR5-Δ32 AIDS-resistance allele by the coalescence of haplotypes. Am J Hum Genet. 1998;62:1507-1515.
-
(1998)
Am J Hum Genet
, vol.62
, pp. 1507-1515
-
-
Stephens, J.C.1
Reich, D.E.2
Goldstein, D.B.3
-
44
-
-
0035126472
-
Characterization of high-risk HIV-1 seronegative hemophiliacs
-
Salkowitz JR, Purvis SF, Meyerson H, et al. Characterization of high-risk HIV-1 seronegative hemophiliacs. Clin Immunol. 2001;98:200-211.
-
(2001)
Clin Immunol
, vol.98
, pp. 200-211
-
-
Salkowitz, J.R.1
Purvis, S.F.2
Meyerson, H.3
-
45
-
-
0037172396
-
Persistence of dual-tropic HIV-1 in an individual homozygous for the CCR5 Δ32 allele
-
Gorry PR, Zhang C, Wu S, et al. Persistence of dual-tropic HIV-1 in an individual homozygous for the CCR5 Δ32 allele. Lancet. 2002;359:1832-1834.
-
(2002)
Lancet
, vol.359
, pp. 1832-1834
-
-
Gorry, P.R.1
Zhang, C.2
Wu, S.3
-
46
-
-
17544384752
-
Exclusive and persistent use of the entry coreceptor CXCR4 by human immunodeficiency virus type 1 from a subject homozygous for CCR5 Δ32
-
Michael NL, Nelson JA, Kewal Ramani VN, et al. Exclusive and persistent use of the entry coreceptor CXCR4 by human immunodeficiency virus type 1 from a subject homozygous for CCR5 Δ32. J Virol. 1998;72:6040-6047.
-
(1998)
J Virol
, vol.72
, pp. 6040-6047
-
-
Michael, N.L.1
Nelson, J.A.2
Kewal Ramani, V.N.3
-
47
-
-
33645046393
-
Selective transmission of CCR5-utilizing HIV-1: The 'gatekeeper' problem resolved?
-
Margolis L, Shattock R. Selective transmission of CCR5-utilizing HIV-1: the 'gatekeeper' problem resolved? Nat Rev Microbiol. 2006;4:312-317.
-
(2006)
Nat Rev Microbiol
, vol.4
, pp. 312-317
-
-
Margolis, L.1
Shattock, R.2
-
48
-
-
16044373004
-
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
-
Samson M, Libert F, Doranz BJ, et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature. 1996;382:722-725.
-
(1996)
Nature
, vol.382
, pp. 722-725
-
-
Samson, M.1
Libert, F.2
Doranz, B.J.3
-
49
-
-
0035881173
-
Homozygous and heterozygous CCR5-Δ32 genotypes are associated with resistance to HIV infection
-
Marmor M, Sheppard HW, Donnell D, et al. Homozygous and heterozygous CCR5-Δ32 genotypes are associated with resistance to HIV infection. J Acquir Immune Defic Syndr. 2001;27:472-481.
-
(2001)
J Acquir Immune Defic Syndr
, vol.27
, pp. 472-481
-
-
Marmor, M.1
Sheppard, H.W.2
Donnell, D.3
-
50
-
-
0035818402
-
Effects of CCR5-Δ32, CCR2-64I, and SDF-13′A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data
-
Ioannidis JP, Rosenberg PS, Goedert JJ, et al. Effects of CCR5-Δ32, CCR2-64I, and SDF-13′A alleles on HIV-1 disease progression: an international meta-analysis of individual-patient data. Ann Intern Med. 2001;135:782-795.
-
(2001)
Ann Intern Med
, vol.135
, pp. 782-795
-
-
Ioannidis, J.P.1
Rosenberg, P.S.2
Goedert, J.J.3
-
51
-
-
8244227329
-
Inherited resistance to HIV-1 conferred by an inactivating mutation in CC chemokine receptor 5: Studies in populations with contrasting clinical phenotypes, defined racial background, and quantified risk
-
Zimmerman PA, Buckler-White A, Alkhatib G, et al. Inherited resistance to HIV-1 conferred by an inactivating mutation in CC chemokine receptor 5: studies in populations with contrasting clinical phenotypes, defined racial background, and quantified risk. Mol Med. 1997;3:23-36.
-
(1997)
Mol Med
, vol.3
, pp. 23-36
-
-
Zimmerman, P.A.1
Buckler-White, A.2
Alkhatib, G.3
-
52
-
-
0027537480
-
Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS
-
Koot M, Keet IP, Vos AH, et al. Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS. Ann Intern Med. 1993;118:681-688.
-
(1993)
Ann Intern Med
, vol.118
, pp. 681-688
-
-
Koot, M.1
Keet, I.P.2
Vos, A.H.3
-
53
-
-
0031575431
-
Change in coreceptor use coreceptor use correlates with disease progression in HIV-1-infected individuals
-
Connor RI, Sheridan KE, Ceradini D, Choe S, Landau NR. Change in coreceptor use coreceptor use correlates with disease progression in HIV-1-infected individuals. J Exp Med. 1997;185:621-628.
-
(1997)
J Exp Med
, vol.185
, pp. 621-628
-
-
Connor, R.I.1
Sheridan, K.E.2
Ceradini, D.3
Choe, S.4
Landau, N.R.5
-
54
-
-
17044452367
-
HIV-1-resistance phenotype conferred by combination of two separate inherited mutations of CCR5 gene
-
Quillent C, Oberlin E, Braun J, et al. HIV-1-resistance phenotype conferred by combination of two separate inherited mutations of CCR5 gene. Lancet. 1998;351:14-18.
-
(1998)
Lancet
, vol.351
, pp. 14-18
-
-
Quillent, C.1
Oberlin, E.2
Braun, J.3
-
55
-
-
20044377204
-
The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility
-
Gonzalez E, Kulkarni H, Bolivar H, et al. The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility. Science. 2005;307:1434-1440.
-
(2005)
Science
, vol.307
, pp. 1434-1440
-
-
Gonzalez, E.1
Kulkarni, H.2
Bolivar, H.3
-
56
-
-
21344467949
-
Detection of the CCR5-Δ32 HIV resistance gene in Bronze Age skeletons
-
Hummel S, Schmidt D, Kremeyer B, Herrmann B, Oppermann M. Detection of the CCR5-Δ32 HIV resistance gene in Bronze Age skeletons. Genes Immun. 2005;6:371-374.
-
(2005)
Genes Immun
, vol.6
, pp. 371-374
-
-
Hummel, S.1
Schmidt, D.2
Kremeyer, B.3
Herrmann, B.4
Oppermann, M.5
-
57
-
-
3242877388
-
Evolutionary genetics: Ambiguous role of CCR5 in Y. pestis infection
-
Elvin SJ, Williamson ED, Scott JC, et al. Evolutionary genetics: Ambiguous role of CCR5 in Y. pestis infection. Nature. 2004;430:417.
-
(2004)
Nature
, vol.430
, pp. 417
-
-
Elvin, S.J.1
Williamson, E.D.2
Scott, J.C.3
-
58
-
-
1342346713
-
Evolutionary genetics: CCR5 mutation and plague protection
-
Mecsas J, Franklin G, Kuziel WA, Brubaker RR, Falkow S, Mosier DE. Evolutionary genetics: CCR5 mutation and plague protection. Nature. 2004;427:606.
-
(2004)
Nature
, vol.427
, pp. 606
-
-
Mecsas, J.1
Franklin, G.2
Kuziel, W.A.3
Brubaker, R.R.4
Falkow, S.5
Mosier, D.E.6
-
59
-
-
0033521155
-
Use of chemokine receptors by poxviruses
-
Lalani AS, Masters J, Zeng W, et al. Use of chemokine receptors by poxviruses. Science. 1999;286:1968-1971.
-
(1999)
Science
, vol.286
, pp. 1968-1971
-
-
Lalani, A.S.1
Masters, J.2
Zeng, W.3
-
60
-
-
0034625771
-
Timing the ancestor of the HIV-1 pandemic strains
-
Korber B, Muldoon M, Theiler J, et al. Timing the ancestor of the HIV-1 pandemic strains. Science. 2000;288:1789-1796.
-
(2000)
Science
, vol.288
, pp. 1789-1796
-
-
Korber, B.1
Muldoon, M.2
Theiler, J.3
-
61
-
-
0035796003
-
CC chemokine receptor 5 and renal-transplant survival
-
Fischereder M, Luckow B, Hocher B, et al. CC chemokine receptor 5 and renal-transplant survival. Lancet. 2001;357:1758-1761.
-
(2001)
Lancet
, vol.357
, pp. 1758-1761
-
-
Fischereder, M.1
Luckow, B.2
Hocher, B.3
-
62
-
-
23744505807
-
A novel small-molecule compound targeting CCR5 and CXCR3 prevents acute and chronic allograft rejection
-
Akashi S, Sho M, Kashizuka H, et al. A novel small-molecule compound targeting CCR5 and CXCR3 prevents acute and chronic allograft rejection. Transplantation. 2005;80:378-384.
-
(2005)
Transplantation
, vol.80
, pp. 378-384
-
-
Akashi, S.1
Sho, M.2
Kashizuka, H.3
-
63
-
-
0040945723
-
Met-RANTES reduces vascular and tubular damage during acute renal transplant rejection: Blocking monocyte arrest and recruitment
-
Grone HJ, Weber C, Weber KS, et al. Met-RANTES reduces vascular and tubular damage during acute renal transplant rejection: blocking monocyte arrest and recruitment. FASEB J. 1999;13:1371-1383.
-
(1999)
FASEB J
, vol.13
, pp. 1371-1383
-
-
Grone, H.J.1
Weber, C.2
Weber, K.S.3
-
64
-
-
31344465937
-
CCR5 deficiency increases risk of symptomatic West Nile virus infection
-
Glass WG, McDermott DH, Lim JK, et al. CCR5 deficiency increases risk of symptomatic West Nile virus infection. J Exp Med. 2006;203:35-40.
-
(2006)
J Exp Med
, vol.203
, pp. 35-40
-
-
Glass, W.G.1
McDermott, D.H.2
Lim, J.K.3
-
65
-
-
26844529383
-
Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection
-
Glass WG, Lim JK, Cholera R, Pletnev AG, Gao JL, Murphy PM. Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection. J Exp Med. 2005;202:1087-1098.
-
(2005)
J Exp Med
, vol.202
, pp. 1087-1098
-
-
Glass, W.G.1
Lim, J.K.2
Cholera, R.3
Pletnev, A.G.4
Gao, J.L.5
Murphy, P.M.6
-
66
-
-
22544457921
-
Age-dependent role for CCR5 in antiviral host defense against herpes simplex virus type 2
-
Ank N, Petersen K, Malmgaard L, Mogensen SC, Paludan SR. Age-dependent role for CCR5 in antiviral host defense against herpes simplex virus type 2. J Virol. 2005;79:9831-9841.
-
(2005)
J Virol
, vol.79
, pp. 9831-9841
-
-
Ank, N.1
Petersen, K.2
Malmgaard, L.3
Mogensen, S.C.4
Paludan, S.R.5
-
67
-
-
13444283754
-
CCR5 plays a critical role in the development of myocarditis and host protection in mice infected with Trypanosoma cruzi
-
Machado FS, Koyama NS, Carregaro V, et al. CCR5 plays a critical role in the development of myocarditis and host protection in mice infected with Trypanosoma cruzi. J Infect Dis. 2005;191:627-636.
-
(2005)
J Infect Dis
, vol.191
, pp. 627-636
-
-
Machado, F.S.1
Koyama, N.S.2
Carregaro, V.3
-
68
-
-
4344588778
-
CCR5-deficient mice control Mycobacterium tuberculosis infection despite increased pulmonary lymphocytic infiltration
-
Algood HM, Flynn JL. CCR5-deficient mice control Mycobacterium tuberculosis infection despite increased pulmonary lymphocytic infiltration. J Immunol. 2004;173:3287-3296.
-
(2004)
J Immunol
, vol.173
, pp. 3287-3296
-
-
Algood, H.M.1
Flynn, J.L.2
-
69
-
-
0038819121
-
CCR5 deficiency decreases susceptibility to experimental cerebral malaria
-
Belnoue E, Kayibanda M, Deschemin JC, et al. CCR5 deficiency decreases susceptibility to experimental cerebral malaria. Blood. 2003;101:4253-4259.
-
(2003)
Blood
, vol.101
, pp. 4253-4259
-
-
Belnoue, E.1
Kayibanda, M.2
Deschemin, J.C.3
-
70
-
-
0037082498
-
The role of CC chemokine receptor 5 in antiviral immunity
-
Nansen A, Christensen JP, Andreasen SO, Bartholdy C, Christensen JE, Thomsen AR. The role of CC chemokine receptor 5 in antiviral immunity. Blood. 2002;99:1237-1245.
-
(2002)
Blood
, vol.99
, pp. 1237-1245
-
-
Nansen, A.1
Christensen, J.P.2
Andreasen, S.O.3
Bartholdy, C.4
Christensen, J.E.5
Thomsen, A.R.6
-
71
-
-
0035885037
-
Reduced macrophage infiltration and demyelination in mice lacking the chemokine receptor CCR5 following infection with a neurotropic coronavirus
-
Glass WG, Liu MT, Kuziel WA, Lane TE. Reduced macrophage infiltration and demyelination in mice lacking the chemokine receptor CCR5 following infection with a neurotropic coronavirus. Virology. 2001;288:8-17.
-
(2001)
Virology
, vol.288
, pp. 8-17
-
-
Glass, W.G.1
Liu, M.T.2
Kuziel, W.A.3
Lane, T.E.4
-
72
-
-
24744462346
-
Host inflammatory response and development of complications of Chlamydia trachomatis genital infection in CCR5-deficient mice and subfertile women with the CCR5Δ32 gene deletion
-
Barr EL, Ouburg S, Igietseme JU, et al. Host inflammatory response and development of complications of Chlamydia trachomatis genital infection in CCR5-deficient mice and subfertile women with the CCR5Δ32 gene deletion. J Microbiol Immunol Infect. 2005;38:244-254.
-
(2005)
J Microbiol Immunol Infect
, vol.38
, pp. 244-254
-
-
Barr, E.L.1
Ouburg, S.2
Igietseme, J.U.3
-
73
-
-
0037308259
-
Associations of chemokine system polymorphisms with clinical outcomes and treatment responses of chronic hepatitis C
-
Promrat K, McDermott DH, Gonzalez CM, et al. Associations of chemokine system polymorphisms with clinical outcomes and treatment responses of chronic hepatitis C. Gastroenterology. 2003;124:352-360.
-
(2003)
Gastroenterology
, vol.124
, pp. 352-360
-
-
Promrat, K.1
McDermott, D.H.2
Gonzalez, C.M.3
-
74
-
-
22644440543
-
The CCR5-Δ32 mutation: Impact on disease outcome in individuals with hepatitis C infection from a single source
-
Goulding C, McManus R, Murphy A, et al. The CCR5-Δ32 mutation: impact on disease outcome in individuals with hepatitis C infection from a single source. Gut. 2005;54:1157-1161.
-
(2005)
Gut
, vol.54
, pp. 1157-1161
-
-
Goulding, C.1
McManus, R.2
Murphy, A.3
-
75
-
-
3042601653
-
CC-chemokine receptor 5 (CCR5) in hepatitis C: At the crossroads of the antiviral immune response?
-
Ahlenstiel G, Woitas RP, Rockstroh J, Spengler U. CC-chemokine receptor 5 (CCR5) in hepatitis C: at the crossroads of the antiviral immune response? J Antimicrob Chemother. 2004;53:895-898.
-
(2004)
J Antimicrob Chemother
, vol.53
, pp. 895-898
-
-
Ahlenstiel, G.1
Woitas, R.P.2
Rockstroh, J.3
Spengler, U.4
-
76
-
-
0027378573
-
A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1
-
Muster T, Steindl F, Purtscher M, et al. A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1. J Virol. 1993;67:6642-6647.
-
(1993)
J Virol
, vol.67
, pp. 6642-6647
-
-
Muster, T.1
Steindl, F.2
Purtscher, M.3
-
77
-
-
0028291731
-
Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1
-
Roben P, Moore JP, Thali M, Sodroski J, Barbas CF III, Burton DR. Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1. J Virol. 1994;68:4821-4828.
-
(1994)
J Virol
, vol.68
, pp. 4821-4828
-
-
Roben, P.1
Moore, J.P.2
Thali, M.3
Sodroski, J.4
Barbas III, C.F.5
Burton, D.R.6
-
78
-
-
0031936306
-
Neutralization sensitivity of human immunodeficiency virus type 1 primary isolates to antibodies and CD4-based reagents is independent of coreceptor usage
-
Trkola A, Ketas T, Kewalramani VN, et al. Neutralization sensitivity of human immunodeficiency virus type 1 primary isolates to antibodies and CD4-based reagents is independent of coreceptor usage. J Virol. 1998;72:1876-1885.
-
(1998)
J Virol
, vol.72
, pp. 1876-1885
-
-
Trkola, A.1
Ketas, T.2
Kewalramani, V.N.3
-
79
-
-
0034759882
-
Broadly neutralizing antibodies targeted to the membraneproximal external region of human immunodeficiency virus type 1 glycoprotein gp41
-
Zwick MB, Labrijn AF, Wang M, et al. Broadly neutralizing antibodies targeted to the membraneproximal external region of human immunodeficiency virus type 1 glycoprotein gp41. J Virol. 2001;75:10892-10905.
-
(2001)
J Virol
, vol.75
, pp. 10892-10905
-
-
Zwick, M.B.1
Labrijn, A.F.2
Wang, M.3
-
80
-
-
20944446452
-
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
-
Trkola A, Kuster H, Rusert P, et al. Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies. Nat Med. 2005;11:615-622.
-
(2005)
Nat Med
, vol.11
, pp. 615-622
-
-
Trkola, A.1
Kuster, H.2
Rusert, P.3
-
81
-
-
0026662175
-
Phase I study of continuous-infusion soluble CD4 as a single agent and in combination with oral dideoxyinosine therapy in children with symptomatic human immunodeficiency virus infection
-
Husson RN, Chung Y, Mordenti J, et al. Phase I study of continuous-infusion soluble CD4 as a single agent and in combination with oral dideoxyinosine therapy in children with symptomatic human immunodeficiency virus infection. J Pediatr. 1992;121:627-633.
-
(1992)
J Pediatr
, vol.121
, pp. 627-633
-
-
Husson, R.N.1
Chung, Y.2
Mordenti, J.3
-
82
-
-
0027976755
-
The effects of high-dose recombinant soluble CD4 on human immunodeficiency virus type 1 viremia
-
Schacker T, Coombs RW, Collier AC, et al. The effects of high-dose recombinant soluble CD4 on human immunodeficiency virus type 1 viremia. J Infect Dis. 1994;169:37-40.
-
(1994)
J Infect Dis
, vol.169
, pp. 37-40
-
-
Schacker, T.1
Coombs, R.W.2
Collier, A.C.3
-
83
-
-
9144250171
-
Treatment of advanced human immunodeficiency virus type 1 disease with the viral entry inhibitor PRO 542
-
Jacobson JM, Israel RJ, Lowy I, et al. Treatment of advanced human immunodeficiency virus type 1 disease with the viral entry inhibitor PRO 542. Antimicrob Agents Chemother. 2004;48:423-429.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 423-429
-
-
Jacobson, J.M.1
Israel, R.J.2
Lowy, I.3
-
84
-
-
2442455279
-
A novel class of HIV-1 inhibitors that targets the viral envelope and inhibits CD4 receptor binding
-
Wang HG, Williams RE, Lin PF. A novel class of HIV-1 inhibitors that targets the viral envelope and inhibits CD4 receptor binding. Curr Pharm Des. 2004;10:1785-1793.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 1785-1793
-
-
Wang, H.G.1
Williams, R.E.2
Lin, P.F.3
-
85
-
-
27744496272
-
Drug firms donate compounds for anti-HIV gel
-
Towie N. Drug firms donate compounds for anti-HIV gel. Nature. 2005;438:6-7.
-
(2005)
Nature
, vol.438
, pp. 6-7
-
-
Towie, N.1
-
86
-
-
27744571425
-
Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion
-
Veazey RS, Klasse PJ, Schader SM, et al. Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion. Nature. 2005;438:99-102.
-
(2005)
Nature
, vol.438
, pp. 99-102
-
-
Veazey, R.S.1
Klasse, P.J.2
Schader, S.M.3
-
87
-
-
33646342770
-
Microbicides and other topical strategies to prevent vaginal transmission of HIV
-
Lederman MM, Offord RE, Hartley O. Microbicides and other topical strategies to prevent vaginal transmission of HIV. Nat Rev Immunol. 2006;6:371-382.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 371-382
-
-
Lederman, M.M.1
Offord, R.E.2
Hartley, O.3
-
88
-
-
1642391068
-
Enfuvirtide: The first therapy to inhibit the entry of HIV-1 into host CD4 lymphocytes
-
Matthews T, Salgo M, Greenberg M, Chung J, DeMasi R, Bolognesi D. Enfuvirtide: the first therapy to inhibit the entry of HIV-1 into host CD4 lymphocytes. Nat Rev Drug Discov. 2004;3:215-225.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 215-225
-
-
Matthews, T.1
Salgo, M.2
Greenberg, M.3
Chung, J.4
DeMasi, R.5
Bolognesi, D.6
-
89
-
-
14844333093
-
Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection
-
Moyle GJ, Wildfire A, Mandalia S, et al. Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection. J Infect Dis. 2005;191:866-872.
-
(2005)
J Infect Dis
, vol.191
, pp. 866-872
-
-
Moyle, G.J.1
Wildfire, A.2
Mandalia, S.3
-
90
-
-
9344239350
-
Medicinal chemistry applied to a synthetic protein: Development of highly potent HIV entry inhibitors
-
Hartley O, Gaertner H, Wilken J, et al. Medicinal chemistry applied to a synthetic protein: development of highly potent HIV entry inhibitors. Proc Natl Acad Sci U S A. 2004;101:16460-16465.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 16460-16465
-
-
Hartley, O.1
Gaertner, H.2
Wilken, J.3
-
91
-
-
33645784598
-
Preclinical evaluation of synthetic-2 RANTES as a candidate vaginal microbicide to target CCR5
-
Kish-Catalone TM, Lu W, Gallo RC, Devico AL. Preclinical evaluation of synthetic-2 RANTES as a candidate vaginal microbicide to target CCR5. Antimicrob Agents Chemother. 2006;50:1497-1509.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 1497-1509
-
-
Kish-Catalone, T.M.1
Lu, W.2
Gallo, R.C.3
Devico, A.L.4
-
92
-
-
0030951442
-
Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist
-
Simmons G, Clapham PR, Picard L, et al. Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist. Science. 1997;276:276-279.
-
(1997)
Science
, vol.276
, pp. 276-279
-
-
Simmons, G.1
Clapham, P.R.2
Picard, L.3
-
93
-
-
5644247983
-
Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5
-
Lederman MM, Veazey RS, Offord R, et al. Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5. Science. 2004;306:485-487.
-
(2004)
Science
, vol.306
, pp. 485-487
-
-
Lederman, M.M.1
Veazey, R.S.2
Offord, R.3
-
94
-
-
33745851881
-
Cutting edge: Human beta defensin 3: A novel antagonist of the HIV-1 co-receptor CXCR4
-
Feng Z, Dubyak GR, Lederman MM, Weinberg A. Cutting edge: human beta defensin 3: a novel antagonist of the HIV-1 co-receptor CXCR4. J Immunol. 2006;177:782-786.
-
(2006)
J Immunol
, vol.177
, pp. 782-786
-
-
Feng, Z.1
Dubyak, G.R.2
Lederman, M.M.3
Weinberg, A.4
-
95
-
-
9144240994
-
Human epithelial β-defensins 2 and 3 inhibit HIV-1 replication
-
Quinones-Mateu ME, Lederman MM, Feng Z, et al. Human epithelial β-defensins 2 and 3 inhibit HIV-1 replication. AIDS. 2003;17:F39-F48.
-
(2003)
AIDS
, vol.17
-
-
Quinones-Mateu, M.E.1
Lederman, M.M.2
Feng, Z.3
-
96
-
-
33750337778
-
Characterization of a panel of novel human monoclonal antibodies that specifically antagonize CCR5 and block HIV-1 entry
-
October 30-November 2, Washington, DC. Abstract 2871
-
Roschke V, Clark S, Branco L, et al. Characterization of a panel of novel human monoclonal antibodies that specifically antagonize CCR5 and block HIV-1 entry. Presented at: 44th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; October 30-November 2, 2004; Washington, DC. Abstract 2871.
-
(2004)
44th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Roschke, V.1
Clark, S.2
Branco, L.3
-
97
-
-
15744391870
-
The CCR5 receptor-based mechanism of action of 873140, a potent allosteric noncompetitive HIV entry inhibitor
-
Watson C, Jenkinson S, Kazmierski W, Kenakin T. The CCR5 receptor-based mechanism of action of 873140, a potent allosteric noncompetitive HIV entry inhibitor. Mol Pharmacol. 2005;67:1268-1282.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1268-1282
-
-
Watson, C.1
Jenkinson, S.2
Kazmierski, W.3
Kenakin, T.4
-
98
-
-
20644453529
-
Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D)
-
Marozsan AJ, Kuhmann SE, Morgan T, et al. Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D). Virology. 2005;338:182-199.
-
(2005)
Virology
, vol.338
, pp. 182-199
-
-
Marozsan, A.J.1
Kuhmann, S.E.2
Morgan, T.3
-
99
-
-
28544434492
-
CCR5 antagonists: Hosttargeted antivirals for the treatment of HIV infection
-
Westby M, van der Ryst E. CCR5 antagonists: hosttargeted antivirals for the treatment of HIV infection. Antivir Chem Chemother. 2005;16:339-354.
-
(2005)
Antivir Chem Chemother
, vol.16
, pp. 339-354
-
-
Westby, M.1
Van Der Ryst, E.2
-
101
-
-
33644653540
-
Late virologic breakthrough in treatment-naïve patients on a regimen of combivir plus vicriviroc
-
February 5-8, Denver, Colo. Abstract 161LB
-
Greaves W, Landovitz R, Fatkenheuer G, et al. Late virologic breakthrough in treatment-naïve patients on a regimen of combivir plus vicriviroc. Presented at: XIII Conference on Retroviruses and Opportunistic Infections; February 5-8, 2006; Denver, Colo. Abstract 161LB.
-
(2006)
XIII Conference on Retroviruses and Opportunistic Infections
-
-
Greaves, W.1
Landovitz, R.2
Fatkenheuer, G.3
-
103
-
-
17444393539
-
Reduced risk of AIDS lymphoma in individuals heterozygous for the CCR5-Δ32 mutation
-
Dean M, Jacobson LP, McFarlane G, et al. Reduced risk of AIDS lymphoma in individuals heterozygous for the CCR5-Δ32 mutation. Cancer Res. 1999;59:3561-3564.
-
(1999)
Cancer Res
, vol.59
, pp. 3561-3564
-
-
Dean, M.1
Jacobson, L.P.2
McFarlane, G.3
-
104
-
-
18644369147
-
The appealing story of HIV entry inhibitors: from discovery of biological mechanisms to drug development
-
Castagna A, Biswas P, Beretta A, Lazzarin A. The appealing story of HIV entry inhibitors: from discovery of biological mechanisms to drug development. Drugs. 2005;65:879-904.
-
(2005)
Drugs
, vol.65
, pp. 879-904
-
-
Castagna, A.1
Biswas, P.2
Beretta, A.3
Lazzarin, A.4
-
105
-
-
4143090383
-
Immune restoration disease after antiretroviral therapy
-
French MA, Price P, Stone SF. Immune restoration disease after antiretroviral therapy. AIDS. 2004;18:1615-1627.
-
(2004)
AIDS
, vol.18
, pp. 1615-1627
-
-
French, M.A.1
Price, P.2
Stone, S.F.3
-
106
-
-
0037702193
-
The immune reconstitution inflammatory syndrome
-
Shelburne SA III, Hamill RJ. The immune reconstitution inflammatory syndrome. AIDS Rev. 2003;5:67-79.
-
(2003)
AIDS Rev
, vol.5
, pp. 67-79
-
-
Shelburne III, S.A.1
Hamill, R.J.2
-
107
-
-
4644342929
-
CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract
-
Brenchley JM, Schacker TW, Ruff LE, et al. CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J Exp Med. 2004;200:749-759.
-
(2004)
J Exp Med
, vol.200
, pp. 749-759
-
-
Brenchley, J.M.1
Schacker, T.W.2
Ruff, L.E.3
-
108
-
-
0027549618
-
Distribution of SIV infection in the gastrointestinal tract of rhesus macaques at early and terminal stages of AIDS
-
Heise C, Vogel P, Miller CJ, Lackner A, Dandekar S. Distribution of SIV infection in the gastrointestinal tract of rhesus macaques at early and terminal stages of AIDS. J Med Primatol. 1993;22:187-193.
-
(1993)
J Med Primatol
, vol.22
, pp. 187-193
-
-
Heise, C.1
Vogel, P.2
Miller, C.J.3
Lackner, A.4
Dandekar, S.5
-
109
-
-
17844374605
-
Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection
-
Mattapallil JJ, Douek DC, Hill B, Nishimura Y, Martin M, Roederer M. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature. 2005;434:1093-1097.
-
(2005)
Nature
, vol.434
, pp. 1093-1097
-
-
Mattapallil, J.J.1
Douek, D.C.2
Hill, B.3
Nishimura, Y.4
Martin, M.5
Roederer, M.6
-
110
-
-
0032540418
-
Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection
-
Veazey RS, DeMaria M, Chalifoux LV, et al. Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science. 1998;280:427-431.
-
(1998)
Science
, vol.280
, pp. 427-431
-
-
Veazey, R.S.1
DeMaria, M.2
Chalifoux, L.V.3
-
111
-
-
0142030023
-
Nadir CD4+ T-cell count and numbers of CD28+ CD4+ T-cells predict functional responses to immunizations in chronic HIV-1 infection
-
Lange CG, Lederman MM, Medvik K, et al. Nadir CD4+ T-cell count and numbers of CD28+ CD4+ T-cells predict functional responses to immunizations in chronic HIV-1 infection. AIDS. 2003;17:2015-2023.
-
(2003)
AIDS
, vol.17
, pp. 2015-2023
-
-
Lange, C.G.1
Lederman, M.M.2
Medvik, K.3
-
112
-
-
0033985563
-
Response to immunization with recall and neoantigens after prolonged administration of an HIV-1 protease inhibitorcontaining regimen
-
Valdez H, Smith KY, Landay A, et al; ACTG 375 Team and AIDS Clinical Trials Group. Response to immunization with recall and neoantigens after prolonged administration of an HIV-1 protease inhibitorcontaining regimen. AIDS. 2000;14:11-21.
-
(2000)
AIDS
, vol.14
, pp. 11-21
-
-
Valdez, H.1
Smith, K.Y.2
Landay, A.3
-
113
-
-
33644658900
-
Challenges of developing R5 inhibitors in antiretroviral naive HIV-infected patients
-
Deeks SG. Challenges of developing R5 inhibitors in antiretroviral naive HIV-infected patients. Lancet. 2006;367:711-713.
-
(2006)
Lancet
, vol.367
, pp. 711-713
-
-
Deeks, S.G.1
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