Characterization of high-risk HIV-1 seronegative hemophiliacs

Clinical Immunology

Volumn 98, Issue 2, 2001, Pages 200-211

  Salkowitz, Janelle R ^a   Purvis, Scott F ^a   Meyerson, Howard ^a   Zimmerman, Peter ^a   O'Brien, Thomas R ^b   Aledort, Louis ^c   Eyster, M Elaine ^d   Hilgartner, Margaret ^e   Kessler, Craig ^f   Konkle, Barbara A ^g   White II, Gilbert C ^h   Goedert, James J ^b   Lederman, Michael M ^a  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c MOUNT SINAI MEDICAL CENTER   (United States)

^d PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^e NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^f GEORGETOWN UNIVERSITY   (United States)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

^h UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Alloreactive antibodies; CCR5; HIV 1; HLA; Multicenter hemophilia cohort study; chemokines

Indexed keywords

BETA CHEMOKINE;

ALLOIMMUNITY; ARTICLE; BLOOD SAMPLING; BLOOD TRANSFUSION; COHORT ANALYSIS; CONTAMINATION; GENETIC SUSCEPTIBILITY; HEMOPHILIA; HIGH RISK POPULATION; HLA SYSTEM; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; SEROCONVERSION;

EID: 0035126472     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1006/clim.2000.4969     Document Type: Article

References (48)

1. Heterosexual transmission of human immunodeficiency virus: Association with severe depletion of T-helper lymphocytes in men with hemophilia
2. Risk of human immunodeficiency virus transmission from heterosexual adults with transfusion-associated infections
3. Naturally occurring IgG anti-HLA alloantibody does not correlate with HIV type 1 resistance in Nairobi prostitutes
4. HIV-1 infection incidence among persons with hemophilia in the United States and western Europe, 1978-1990. Multicenter Hemophilia Cohort Study
5. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CCR5 structural gene
6. The role of a mutant CCR5 allele in HIV-1 transmission and disease progression
7. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
8. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
9. Inherited resistance to HIV-1 conferred by an inactivating mutation in CC chemokine receptor 5: Studies in populations with contrasting clinical phenotypes, defined racial background, and quantified risk
10. CCR5-delta 32 gene deletion in HIV-1 infected patients
11. CCR5-delta 32 gene deletion in HIV-1 infected patients
12. HIV-1 infection in a man homozygous for CCR5 delta 32
13. Exclusive and persistent use of the entry coreceptor CXCR4 by human immunodeficiency virus type 1 from a subject homozygous for CCR5 delta32
14. HIV-1-resistance phenotype conferred by combination of two separate inherited mutations of CCR5 gene
15. HIV type 1 resistance in Kenyan sex workers is not associated with altered cellular susceptibility to HIV type 1 infection or enhanced beta-chemokine production
16. Protective role of beta-chemokines associated with HIV-specific Th responses against perinatal HIV transmission
17. Human immunodeficiency virus (HIV)-specific cytotoxic T lymphocyte activity in HIV-exposed seronegative persons
18. Protection against human immunodeficiency virus type 1 infection in persons with repeated exposure: Evidence for T cell immunity in the absence of inherited CCR5 coreceptor defects
19. C-C chemokines, pivotal in protection against HIV type 1 infection
20. Quantitation of CD38 expression using QuantiBRITE beads
21. Decreased susceptibility of peripheral blood mononuclear cells from individuals heterozygous for a mutant CCR5 allele to HIV infection
22. Protection against parenteral HIV-1 infection by homozygous deletion in the C-C chemokine receptor 5 gene
23. The HIV type 1 coreceptor CCR5 and its role in viral transmission and disease progression
24. + T cells
25. Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high risk sexual exposures
26. Expression and use of human immunodeficiency virus type 1 coreceptors by human alveolar macrophages
27. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi
28. Alloimmunization as an AIDS vaccine?
29. Alloimmunization to prevent AIDS?
30. Alloimmunization for immune-based therapy and vaccine design against HIV/AIDS
31. HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
32. Activation of blood T lymphocytes down-regulates CXCR4 expression and interferes with propagation of X4 HIV strains
33. Human immunodeficiency virus (HIV) type 1 infection status and in vitro susceptibility to HIV infection among high-risk HIV-1-seronegative hemophiliacs
34. Human immunodeficiency virus type 1-specific cytotoxic T lymphocytes (CTL), virus load, and CD4 T cell loss: Evidence supporting a protective role for CTL in vivo
35. The acquisition of host-encoded proteins by nascent HIV-1
36. Immunization with class I human histocompatibility leukocyte antigen can protect macaques against challenge infection with SIVmac-32H
37. Macaques immunized with HLA-DR are protected from challenge with simian immunodeficiency virus
38. Mechanisms of resistance of HIV-1 primary isolates to complement-mediated lysis
39. Induction of HIV-1 replication by allogeneic stimulation
40. Strong correlation between the complement-mediated antibody-dependent enhancement of HIV-1 infection and plasma viral load
41. Immune complexes containing human immunodeficiency virus type 1 primary isolates bind to lymphoid tissue B lymphocytes and are infectious for T lymphocytes
42. B cells of HIV-1-infected patients bind virions through CD21-complement interactions and transmit infectious virus to activated T cells
43. Allogeneic leukocytes but not therapeutic blood elements induce reactivation and dissemination of latent human immunodeficiency virus type 1 infection: Implications for transfusion support of infected patients
44. Human immunodeficiency virus type 1 activation after blood transfusion
45. Preferential coreceptor utilization and cytopathicity by dual-tropic HIV-1 in human lymphoid tissue ex vivo
46. CXCR4 utilization is sufficient to trigger CD4+ T cell depletion in HIV-1-infected human lymphoid tissue