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Volumn 2, Issue 7, 2006, Pages 0911-0919

Modeling chromosomes in mouse to explore the function of genes, genomic disorders, and chromosomal organization

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINASE;

EID: 33746659123     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0020086     Document Type: Review
Times cited : (36)

References (117)
  • 1
    • 1842537138 scopus 로고
    • Radiation genetics
    • Green EL, editor. New York: McGraw-Hill
    • Green EL, Roderick TH (1966) Radiation genetics. In: Green EL, editor. Biology of the laboratory mouse. New York: McGraw-Hill. pp. 87-150.
    • (1966) Biology of the Laboratory Mouse , pp. 87-150
    • Green, E.L.1    Roderick, T.H.2
  • 3
    • 0033865564 scopus 로고    scopus 로고
    • Interdigitated deletion complexes on mouse chromosome 5 induced by irradiation of embryonic stem cells
    • Schimenti JC, Libby BJ, Bergstrom RA, Wilson LA, Naf D, et al. (2000) Interdigitated deletion complexes on mouse chromosome 5 induced by irradiation of embryonic stem cells. Genome Res 10: 1043-1050.
    • (2000) Genome Res , vol.10 , pp. 1043-1050
    • Schimenti, J.C.1    Libby, B.J.2    Bergstrom, R.A.3    Wilson, L.A.4    Naf, D.5
  • 5
    • 0031018818 scopus 로고    scopus 로고
    • Chromosomal deletion complexes in mice by radiation of embryonic stem cells
    • You Y, Bergstrom R, Klemm M, Lederman B, Nelson H, et al. (1997) Chromosomal deletion complexes in mice by radiation of embryonic stem cells. Nat Genet 15: 285-288.
    • (1997) Nat Genet , vol.15 , pp. 285-288
    • You, Y.1    Bergstrom, R.2    Klemm, M.3    Lederman, B.4    Nelson, H.5
  • 6
    • 0032054547 scopus 로고    scopus 로고
    • Generation of mutant mice with large chromosomal deletion by use of irradiated ES cells - Analysis of large deletion around hprt locus of ES cell
    • Kushi A, Edamura K, Noguchi M, Akiyama K, Nishi Y, et al. (1998) Generation of mutant mice with large chromosomal deletion by use of irradiated ES cells - Analysis of large deletion around hprt locus of ES cell. Mamm Genome 9: 269-273.
    • (1998) Mamm Genome , vol.9 , pp. 269-273
    • Kushi, A.1    Edamura, K.2    Noguchi, M.3    Akiyama, K.4    Nishi, Y.5
  • 7
    • 0028222953 scopus 로고
    • Targeting frequency for deletion vectors in embryonic stem cells
    • Zhang H, Hasty P, Bradley A (1994) Targeting frequency for deletion vectors in embryonic stem cells. Mol Cell Biol 14: 2404-2410.
    • (1994) Mol Cell Biol , vol.14 , pp. 2404-2410
    • Zhang, H.1    Hasty, P.2    Bradley, A.3
  • 8
    • 0027280936 scopus 로고
    • Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
    • Gu H, Zou YR, Rajewsky K (1993) Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell 73: 1155-1164.
    • (1993) Cell , vol.73 , pp. 1155-1164
    • Gu, H.1    Zou, Y.R.2    Rajewsky, K.3
  • 9
    • 0029119145 scopus 로고
    • Cre-mediated site-specific translocation between nonhomologous mouse chromosomes
    • U S A
    • Van Deursen J, Fornerod M, Van Rees B, Grosveld G (1995) Cre-mediated site-specific translocation between nonhomologous mouse chromosomes. Proc Natl Acad Sci U S A 92: 7376-7380.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 7376-7380
    • Van Deursen, J.1    Fornerod, M.2    Van Rees, B.3    Grosveld, G.4
  • 10
    • 0029562967 scopus 로고
    • Chromosome engineering in mice
    • Ramirez-Solis R, Liu P, Bradley A (1995) Chromosome engineering in mice. Nature 378: 720-724.
    • (1995) Nature , vol.378 , pp. 720-724
    • Ramirez-Solis, R.1    Liu, P.2    Bradley, A.3
  • 11
    • 0028950996 scopus 로고
    • A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination
    • Smith AJ, De Sousa MA, Kwabi-Addo B, Heppell-Parton A, Impey H, et al. (1995) A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination. Nat Genet 9: 376-385.
    • (1995) Nat Genet , vol.9 , pp. 376-385
    • Smith, A.J.1    De Sousa, M.A.2    Kwabi-Addo, B.3    Heppell-Parton, A.4    Impey, H.5
  • 12
    • 0031770816 scopus 로고    scopus 로고
    • Engineering chromosomes in mice through targeted meiotic recombination (TAMERE)
    • Herault Y, Rassoulzadegan M, Cuzin F, Duboule D (1998) Engineering chromosomes in mice through targeted meiotic recombination (TAMERE). Nat Genet 20: 381-384.
    • (1998) Nat Genet , vol.20 , pp. 381-384
    • Herault, Y.1    Rassoulzadegan, M.2    Cuzin, F.3    Duboule, D.4
  • 13
    • 0033152654 scopus 로고    scopus 로고
    • A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice
    • Zheng B, Mills AA, Bradley A (1999) A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice. Nucleic Acids Res 27: 2354-2360.
    • (1999) Nucleic Acids Res , vol.27 , pp. 2354-2360
    • Zheng, B.1    Mills, A.A.2    Bradley, A.3
  • 16
    • 23744508506 scopus 로고    scopus 로고
    • Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations
    • Wilson L, Ching YH, Farias M, Hartford SA, Howell G, et al. (2005) Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations. Genome Res 15: 1095-1105.
    • (2005) Genome Res , vol.15 , pp. 1095-1105
    • Wilson, L.1    Ching, Y.H.2    Farias, M.3    Hartford, S.A.4    Howell, G.5
  • 17
    • 0025663975 scopus 로고
    • Segmental trisomy of murine chromosome 16: A new model system for studying Down syndrome
    • Davisson MT, Schmidt C, Akeson EC (1990) Segmental trisomy of murine chromosome 16: A new model system for studying Down syndrome. Prog Clin Biol Res 360: 263-280.
    • (1990) Prog Clin Biol Res , vol.360 , pp. 263-280
    • Davisson, M.T.1    Schmidt, C.2    Akeson, E.C.3
  • 18
    • 0029114706 scopus 로고
    • A mouse model for Down syndrome exhibits learning and behaviour deficits
    • Reeves RH, Irving NG, Moran TH, Wohn A, Kitt C, et al. (1995) A mouse model for Down syndrome exhibits learning and behaviour deficits. Nat Genet 11: 177-184.
    • (1995) Nat Genet , vol.11 , pp. 177-184
    • Reeves, R.H.1    Irving, N.G.2    Moran, T.H.3    Wohn, A.4    Kitt, C.5
  • 19
    • 0032033198 scopus 로고    scopus 로고
    • Utility of C57BL/6J X 129/SvJae embryonic stem cells for generating chromosomal deletions: Tolerance to gamma radiation and microsatellite polymorphism
    • You Y, Bersgtram R, Klemm M, Nelson H, Jaenisch R, et al. (1998) Utility of C57BL/6J X 129/SvJae embryonic stem cells for generating chromosomal deletions: Tolerance to gamma radiation and microsatellite polymorphism. Mamm Genome 9: 232-234.
    • (1998) Mamm Genome , vol.9 , pp. 232-234
    • You, Y.1    Bersgtram, R.2    Klemm, M.3    Nelson, H.4    Jaenisch, R.5
  • 21
    • 0035448880 scopus 로고    scopus 로고
    • Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations
    • Spitz F, Gonzalez F, Peichel C, Vogt TF, Duboule D, et al. (2001) Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations. Genes Dev 15: 2209-2214.
    • (2001) Genes Dev , vol.15 , pp. 2209-2214
    • Spitz, F.1    Gonzalez, F.2    Peichel, C.3    Vogt, T.F.4    Duboule, D.5
  • 22
    • 0029854152 scopus 로고    scopus 로고
    • Synpolydactyly in mice with a targeted deficiency in the HoxD complex
    • Zakany J, Duboule D (1996) Synpolydactyly in mice with a targeted deficiency in the HoxD complex. Nature 384: 69-71.
    • (1996) Nature , vol.384 , pp. 69-71
    • Zakany, J.1    Duboule, D.2
  • 23
    • 7444231620 scopus 로고    scopus 로고
    • A chromosome 21 critical region does not cause specific Down syndrome phenotypes
    • Olson LE, Richtsmeier JT, Leszl J, Reeves RH (2004) A chromosome 21 critical region does not cause specific Down syndrome phenotypes. Science 306: 687-690.
    • (2004) Science , vol.306 , pp. 687-690
    • Olson, L.E.1    Richtsmeier, J.T.2    Leszl, J.3    Reeves, R.H.4
  • 24
    • 12944293167 scopus 로고    scopus 로고
    • Normal cardiovascular development in mice deficient for 16 genes in 550 kb of the velocardiofacial/DiGeorge syndrome region
    • U S A
    • Puech A, Saint-Jore B, Merscher S, Russell RG, Cherif D, et al. (2000) Normal cardiovascular development in mice deficient for 16 genes in 550 kb of the velocardiofacial/DiGeorge syndrome region. Proc Natl Acad Sci U S A 97: 10090-10095.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 10090-10095
    • Puech, A.1    Saint-Jore, B.2    Merscher, S.3    Russell, R.G.4    Cherif, D.5
  • 25
    • 0034656095 scopus 로고    scopus 로고
    • Hox C cluster genes are dispensable for overall body plan of mouse embryonic development
    • Suemori H, Noguchi S (2000) Hox C cluster genes are dispensable for overall body plan of mouse embryonic development. Dev Biol 220: 333-342.
    • (2000) Dev Biol , vol.220 , pp. 333-342
    • Suemori, H.1    Noguchi, S.2
  • 26
    • 13444274511 scopus 로고    scopus 로고
    • A new model mouse for Duchenne muscular dystrophy produced by 2.4 Mb deletion of dystrophin gene using Cre-loxP recombination system
    • Kudoh H, Ikeda H, Kakitani M, Ueda A, Hayasaka M, et al. (2005) A new model mouse for Duchenne muscular dystrophy produced by 2.4 Mb deletion of dystrophin gene using Cre-loxP recombination system. Biochem Biophys Res Commun 328: 507-516.
    • (2005) Biochem Biophys Res Commun , vol.328 , pp. 507-516
    • Kudoh, H.1    Ikeda, H.2    Kakitani, M.3    Ueda, A.4    Hayasaka, M.5
  • 27
    • 0029954239 scopus 로고    scopus 로고
    • Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells
    • U S A
    • Li ZW, Stark G, Gotz J, Rulicke T, Gschwind M, et al. (1996) Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells. Proc Natl Acad Sci U S A 93: 6158-6162.
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 6158-6162
    • Li, Z.W.1    Stark, G.2    Gotz, J.3    Rulicke, T.4    Gschwind, M.5
  • 28
    • 0033613399 scopus 로고    scopus 로고
    • Predetermined chromosomal deletion encompassing the Nf-1 gene
    • Schlake T, Schupp I, Kutsche K, Mincheva A, Lichter P, et al. (1999) Predetermined chromosomal deletion encompassing the Nf-1 gene. Oncogene 18: 6078-6082.
    • (1999) Oncogene , vol.18 , pp. 6078-6082
    • Schlake, T.1    Schupp, I.2    Kutsche, K.3    Mincheva, A.4    Lichter, P.5
  • 29
    • 0033950653 scopus 로고    scopus 로고
    • Genomic interval engineering of mice identifies a novel modulator of triglyceride production
    • U S A
    • Zhu Y, Jong MC, Frazer KA, Gong E, Krauss RM, et al. (2000) Genomic interval engineering of mice identifies a novel modulator of triglyceride production. Proc Natl Acad Sci U S A 97: 1137-1142.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 1137-1142
    • Zhu, Y.1    Jong, M.C.2    Frazer, K.A.3    Gong, E.4    Krauss, R.M.5
  • 31
    • 0033985437 scopus 로고    scopus 로고
    • Engineering mouse chromosomes with Cre-loxP: Range, efficiency, and somatic applications
    • Zheng B, Sage M, Sheppeard EA, Jurecic V, Bradley A (2000) Engineering mouse chromosomes with Cre-loxP: Range, efficiency, and somatic applications. Mol Cell Biol 20: 648-655.
    • (2000) Mol Cell Biol , vol.20 , pp. 648-655
    • Zheng, B.1    Sage, M.2    Sheppeard, E.A.3    Jurecic, V.4    Bradley, A.5
  • 32
    • 0031770040 scopus 로고    scopus 로고
    • Embryonic lethality and tumorigenesis caused by segmental aneuploidy on mouse chromosome 11
    • Liu P, Zhang H, McLellan A, Vogel H, Bradley A (1998) Embryonic lethality and tumorigenesis caused by segmental aneuploidy on mouse chromosome 11. Genetics 150: 1155-1168.
    • (1998) Genetics , vol.150 , pp. 1155-1168
    • Liu, P.1    Zhang, H.2    McLellan, A.3    Vogel, H.4    Bradley, A.5
  • 33
    • 0035490099 scopus 로고    scopus 로고
    • Engineering chromosomal rearrangements in mice
    • Yu Y, Bradley A (2001) Engineering chromosomal rearrangements in mice. Nat Rev Genet 2: 780-790.
    • (2001) Nat Rev Genet , vol.2 , pp. 780-790
    • Yu, Y.1    Bradley, A.2
  • 34
    • 22144484182 scopus 로고    scopus 로고
    • Long-range chromosomal engineering is more efficient in vitro than in vivo
    • Olson LE, Tien J, South S, Reeves RH (2005) Long-range chromosomal engineering is more efficient in vitro than in vivo. Transgenic Res 14: 325-332.
    • (2005) Transgenic Res , vol.14 , pp. 325-332
    • Olson, L.E.1    Tien, J.2    South, S.3    Reeves, R.H.4
  • 35
    • 0027264139 scopus 로고
    • Genomic targeting with purified Cre recombinase
    • Baubonis W, Sauer B (1993) Genomic targeting with purified Cre recombinase. Nucleic Acids Res 21: 2025-2029.
    • (1993) Nucleic Acids Res , vol.21 , pp. 2025-2029
    • Baubonis, W.1    Sauer, B.2
  • 36
    • 0033567699 scopus 로고    scopus 로고
    • Segmental genomic replacement in embryonic stem cells by double lox targeting
    • Soukharev S, Miller JL, Sauer B (1999) Segmental genomic replacement in embryonic stem cells by double lox targeting. Nucleic Acids Res 27: e21.
    • (1999) Nucleic Acids Res , vol.27
    • Soukharev, S.1    Miller, J.L.2    Sauer, B.3
  • 37
    • 0030612755 scopus 로고    scopus 로고
    • Brief expression of a GFP cre fusion gene in embryonic stem cells allows rapid retrieval of site-specific genomic deletions
    • Gagneten S, Le Y, Miller J, Sauer B (1997) Brief expression of a GFP cre fusion gene in embryonic stem cells allows rapid retrieval of site-specific genomic deletions. Nucleic Acids Res 25: 3326-3331.
    • (1997) Nucleic Acids Res , vol.25 , pp. 3326-3331
    • Gagneten, S.1    Le, Y.2    Miller, J.3    Sauer, B.4
  • 38
    • 0036338128 scopus 로고    scopus 로고
    • Efficient Cre-loxP-induced mitotic recombination in mouse embryonic stem cells
    • Liu P, Jenkins NA, Copeland NG (2002) Efficient Cre-loxP-induced mitotic recombination in mouse embryonic stem cells. Nat Genet 30: 66-72.
    • (2002) Nat Genet , vol.30 , pp. 66-72
    • Liu, P.1    Jenkins, N.A.2    Copeland, N.G.3
  • 39
    • 0035984906 scopus 로고    scopus 로고
    • Efficient biallelic mutagenesis with Cre/loxP-mediated interchromosomal recombination
    • Koike H, Horie K, Fukuyama H, Kondoh G, Nagata S, et al. (2002) Efficient biallelic mutagenesis with Cre/loxP-mediated interchromosomal recombination. EMBO Rep 3: 433-437.
    • (2002) EMBO Rep , vol.3 , pp. 433-437
    • Koike, H.1    Horie, K.2    Fukuyama, H.3    Kondoh, G.4    Nagata, S.5
  • 40
    • 0026635749 scopus 로고
    • A new mouse embryonic stem cell line with good germ line contribution and gene targeting frequency
    • Magin TM, McWhir J, Melton DW (1992) A new mouse embryonic stem cell line with good germ line contribution and gene targeting frequency. Nucleic Acids Res 20: 3795-3796.
    • (1992) Nucleic Acids Res , vol.20 , pp. 3795-3796
    • Magin, T.M.1    McWhir, J.2    Melton, D.W.3
  • 41
    • 3543035792 scopus 로고    scopus 로고
    • Mutagenic insertion and chromosome engineering resource (MICER)
    • Adams DJ, Biggs PJ, Cox T, Davies R, van der Weyden L, et al. (2004) Mutagenic insertion and chromosome engineering resource (MICER). Nat Genet 36: 867-871.
    • (2004) Nat Genet , vol.36 , pp. 867-871
    • Adams, D.J.1    Biggs, P.J.2    Cox, T.3    Davies, R.4    Van Der Weyden, L.5
  • 42
    • 0033989250 scopus 로고    scopus 로고
    • Nested chromosomal deletions induced with retroviral vectors in mice
    • Su H, Wang X, Bradley A (2000) Nested chromosomal deletions induced with retroviral vectors in mice. Nat Genet 24: 92-95.
    • (2000) Nat Genet , vol.24 , pp. 92-95
    • Su, H.1    Wang, X.2    Bradley, A.3
  • 43
    • 0035263599 scopus 로고    scopus 로고
    • Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice
    • Lindsay EA, Vitelli F, Su H, Morishima M, Huynh T, et al. (2001) Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice. Nature 410: 97-101.
    • (2001) Nature , vol.410 , pp. 97-101
    • Lindsay, E.A.1    Vitelli, F.2    Su, H.3    Morishima, M.4    Huynh, T.5
  • 44
    • 8444222330 scopus 로고    scopus 로고
    • Reduced penetrance of craniofacial anomalies as a function of deletion size and genetic background in a chromosome engineered partial mouse model for Smith-Magenis syndrome
    • Yan J, Keener VW, Bi W, Walz K, Bradley A, et al. (2004) Reduced penetrance of craniofacial anomalies as a function of deletion size and genetic background in a chromosome engineered partial mouse model for Smith-Magenis syndrome. Hum Mol Genet 13: 2613-2624.
    • (2004) Hum Mol Genet , vol.13 , pp. 2613-2624
    • Yan, J.1    Keener, V.W.2    Bi, W.3    Walz, K.4    Bradley, A.5
  • 45
    • 0000368049 scopus 로고    scopus 로고
    • Control of colinearity in AbdB genes of the mouse HoxD complex
    • Kondo T, Zakany J, Duboule D (1998) Control of colinearity in AbdB genes of the mouse HoxD complex. Mol Cell 1: 289-300.
    • (1998) Mol Cell , vol.1 , pp. 289-300
    • Kondo, T.1    Zakany, J.2    Duboule, D.3
  • 46
    • 0033617267 scopus 로고    scopus 로고
    • Breaking colinearity in the mouse HoxD complex
    • Kondo T, Duboule D (1999) Breaking colinearity in the mouse HoxD complex. Cell 97: 407-417.
    • (1999) Cell , vol.97 , pp. 407-417
    • Kondo, T.1    Duboule, D.2
  • 47
    • 0343618784 scopus 로고    scopus 로고
    • A large targeted deletion of Hoxb1-Hoxb9 produces a series of single-segment anterior homeotic transformations
    • Medina-Martinez O, Bradley A, Ramirez-Solis R (2000) A large targeted deletion of Hoxb1-Hoxb9 produces a series of single-segment anterior homeotic transformations. Dev Biol 222: 71-83.
    • (2000) Dev Biol , vol.222 , pp. 71-83
    • Medina-Martinez, O.1    Bradley, A.2    Ramirez-Solis, R.3
  • 49
    • 0031832579 scopus 로고    scopus 로고
    • Role of the region 3′ to Xist exon 6 in the counting process of X-chromosome inactivation
    • Clerc P, Avner P (1998) Role of the region 3′ to Xist exon 6 in the counting process of X-chromosome inactivation. Nat Genet 19: 249-253.
    • (1998) Nat Genet , vol.19 , pp. 249-253
    • Clerc, P.1    Avner, P.2
  • 50
    • 0035875043 scopus 로고    scopus 로고
    • Tsix-mediated repression of Xist accumulation is not sufficient for normal random X inactivation
    • Morey C, Arnaud D, Avner P, Clerc P (2001) Tsix-mediated repression of Xist accumulation is not sufficient for normal random X inactivation. Hum Mol Genet 10: 1403-1411.
    • (2001) Hum Mol Genet , vol.10 , pp. 1403-1411
    • Morey, C.1    Arnaud, D.2    Avner, P.3    Clerc, P.4
  • 51
    • 1442338339 scopus 로고    scopus 로고
    • The region 3′ to Xist mediates X chromosome counting and H3 Lys-4 dimethylation within the Xist gene
    • Morey C, Navarro P, Debrand E, Avner P, Rougeulle C, et al. (2004) The region 3′ to Xist mediates X chromosome counting and H3 Lys-4 dimethylation within the Xist gene. EMJO J 23: 594-604.
    • (2004) EMJO J , vol.23 , pp. 594-604
    • Morey, C.1    Navarro, P.2    Debrand, E.3    Avner, P.4    Rougeulle, C.5
  • 52
    • 0037206947 scopus 로고    scopus 로고
    • Targeted disruption of Dkc1, the gene mutated in X-linked dyskeratosis congenita, causes embryonic lethality in mice
    • He J, Navarrete S, Jasinski M, Vulliamy T, Dokal I, et al. (2002) Targeted disruption of Dkc1, the gene mutated in X-linked dyskeratosis congenita, causes embryonic lethality in mice. Oncogene 21: 7740-7744.
    • (2002) Oncogene , vol.21 , pp. 7740-7744
    • He, J.1    Navarrete, S.2    Jasinski, M.3    Vulliamy, T.4    Dokal, I.5
  • 53
    • 18744387205 scopus 로고    scopus 로고
    • Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: Mice with inactivation of the entire TNF/LT locus versus single-knockout mice
    • Kuprash DV, Alimzhanov MB, Tumanov AV, Grivennikov SI, Shakhov AN, et al. (2002) Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: Mice with inactivation of the entire TNF/LT locus versus single-knockout mice. Mol Cell Biol 22: 8626-8634.
    • (2002) Mol Cell Biol , vol.22 , pp. 8626-8634
    • Kuprash, D.V.1    Alimzhanov, M.B.2    Tumanov, A.V.3    Grivennikov, S.I.4    Shakhov, A.N.5
  • 54
    • 0037026572 scopus 로고    scopus 로고
    • Deficient pheromone responses in mice lacking a cluster of vomeronasal receptor genes
    • Del Punta K, Leinders-Zufall T, Rodriguez I, Jukam D, Wysocki CJ, et al. (2002) Deficient pheromone responses in mice lacking a cluster of vomeronasal receptor genes. Nature 419: 70-74.
    • (2002) Nature , vol.419 , pp. 70-74
    • Del Punta, K.1    Leinders-Zufall, T.2    Rodriguez, I.3    Jukam, D.4    Wysocki, C.J.5
  • 55
    • 14944340807 scopus 로고    scopus 로고
    • Chromosomal excision of TCRdelta chain genes is dispensable for alphabeta T cell lineage commitment
    • Khor B, Wehrly TD, Sleckman BP (2005) Chromosomal excision of TCRdelta chain genes is dispensable for alphabeta T cell lineage commitment. Int Immunol 17: 225-232.
    • (2005) Int Immunol , vol.17 , pp. 225-232
    • Khor, B.1    Wehrly, T.D.2    Sleckman, B.P.3
  • 56
    • 0038683341 scopus 로고    scopus 로고
    • An engineered 800 kilobase deletion of Uchl3 and Lmo7 on mouse chromosome 14 causes defects in viability, postnatal growth and degeneration of muscle and retina
    • Semenova E, Wang X, Jablonski MM, Levorse J, Tilghman SM (2003) An engineered 800 kilobase deletion of Uchl3 and Lmo7 on mouse chromosome 14 causes defects in viability, postnatal growth and degeneration of muscle and retina. Hum Mol Genet 12: 1301-1312.
    • (2003) Hum Mol Genet , vol.12 , pp. 1301-1312
    • Semenova, E.1    Wang, X.2    Jablonski, M.M.3    Levorse, J.4    Tilghman, S.M.5
  • 57
    • 0037019185 scopus 로고    scopus 로고
    • Cre-loxP chromosome engineering of a targeted deletion in the mouse corresponding to the 3p21.3 region of homozygous loss in human tumours
    • Smith AJ, Xian J, Richardson M, Johnstone KA, Rabbitts PH (2002) Cre-loxP chromosome engineering of a targeted deletion in the mouse corresponding to the 3p21.3 region of homozygous loss in human tumours. Oncogene 21: 4521-4529.
    • (2002) Oncogene , vol.21 , pp. 4521-4529
    • Smith, A.J.1    Xian, J.2    Richardson, M.3    Johnstone, K.A.4    Rabbitts, P.H.5
  • 58
    • 0038282471 scopus 로고    scopus 로고
    • Allelic phasing of a mouse chromosome 11 deficiency influences p53 tumorigenicity
    • Biggs PJ, Vogel H, Sage M, Martin LA, Donehower LA, et al. (2003) Allelic phasing of a mouse chromosome 11 deficiency influences p53 tumorigenicity. Oncogene 22: 3288-3296.
    • (2003) Oncogene , vol.22 , pp. 3288-3296
    • Biggs, P.J.1    Vogel, H.2    Sage, M.3    Martin, L.A.4    Donehower, L.A.5
  • 59
    • 0034252564 scopus 로고    scopus 로고
    • Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse
    • Buchholz F, Refaeli Y, Trumpp A, Bishop JM (2000) Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse. EMBO Rep 1: 133-139.
    • (2000) EMBO Rep , vol.1 , pp. 133-139
    • Buchholz, F.1    Refaeli, Y.2    Trumpp, A.3    Bishop, J.M.4
  • 60
    • 0034252206 scopus 로고    scopus 로고
    • Interchromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development
    • Collins EC, Pannell R, Simpson EM, Forster A, Rabbitts TH (2000) Interchromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development. EMBO Rep 1: 127-132.
    • (2000) EMBO Rep , vol.1 , pp. 127-132
    • Collins, E.C.1    Pannell, R.2    Simpson, E.M.3    Forster, A.4    Rabbitts, T.H.5
  • 61
    • 27144493049 scopus 로고    scopus 로고
    • Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis
    • Drynan LF, Pannell R, Forster A, Chan NM, Cano F, et al. (2005) Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis. EMBO J 24: 3136-3146.
    • (2005) EMBO J , vol.24 , pp. 3136-3146
    • Drynan, L.F.1    Pannell, R.2    Forster, A.3    Chan, N.M.4    Cano, F.5
  • 62
    • 0345582392 scopus 로고    scopus 로고
    • Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer
    • Forster A, Pannell R, Drynan LF, McCormack M, Collins EC, et al. (2003) Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer. Cancer Cell 3: 449-458.
    • (2003) Cancer Cell , vol.3 , pp. 449-458
    • Forster, A.1    Pannell, R.2    Drynan, L.F.3    McCormack, M.4    Collins, E.C.5
  • 63
    • 17744388353 scopus 로고    scopus 로고
    • Inactivation of Rai1 in mice recapitulates phenotypes observed in chromosome engineered mouse models for Smith-Magenis syndrome
    • Bi W, Ohyama T, Nakamura H, Yan J, Visvanathan J, et al. (2005) Inactivation of Rai1 in mice recapitulates phenotypes observed in chromosome engineered mouse models for Smith-Magenis syndrome. Hum Mol Genet 14: 983-995.
    • (2005) Hum Mol Genet , vol.14 , pp. 983-995
    • Bi, W.1    Ohyama, T.2    Nakamura, H.3    Yan, J.4    Visvanathan, J.5
  • 64
    • 0037965627 scopus 로고    scopus 로고
    • Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: Phenotypic consequences of gene dosage imbalance
    • Walz K, Caratini-Rivera S, Bi W, Fonseca P, Mansouri DL, et al. (2003) Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: Phenotypic consequences of gene dosage imbalance. Mol Cell Biol 23: 3646-3655.
    • (2003) Mol Cell Biol , vol.23 , pp. 3646-3655
    • Walz, K.1    Caratini-Rivera, S.2    Bi, W.3    Fonseca, P.4    Mansouri, D.L.5
  • 65
    • 1242330479 scopus 로고    scopus 로고
    • Behavioral characterization of mouse models for Smith-Magenis syndrome and dup(17)(p11.2p11.2)
    • Walz K, Spencer C, Kaasik K, Lee CC, Lupski JR, et al. (2004) Behavioral characterization of mouse models for Smith-Magenis syndrome and dup(17)(p11.2p11.2). Hum Mol Genet 13: 367-378.
    • (2004) Hum Mol Genet , vol.13 , pp. 367-378
    • Walz, K.1    Spencer, C.2    Kaasik, K.3    Lee, C.C.4    Lupski, J.R.5
  • 66
    • 34547664096 scopus 로고    scopus 로고
    • Genomic disorders: Molecular mechanisms for rearrangements and conveyed phenotypes
    • Lupski JR, Stankiewicz P (2005) Genomic disorders: Molecular mechanisms for rearrangements and conveyed phenotypes. PLoS Genet 1: e49.
    • (2005) PLoS Genet , vol.1
    • Lupski, J.R.1    Stankiewicz, P.2
  • 67
    • 0032837539 scopus 로고    scopus 로고
    • Paternal deletion from Snrpn to Ube3a in the mouse causes hypotonia, growth retardation and partial lethality and provides evidence for a gene contributing to Prader-Willi syndrome
    • Tsai TF, Jiang YH, Bressler J, Armstrong D, Beaudet AL (1999) Paternal deletion from Snrpn to Ube3a in the mouse causes hypotonia, growth retardation and partial lethality and provides evidence for a gene contributing to Prader-Willi syndrome. Hum Mol Genet 8: 1357-1364.
    • (1999) Hum Mol Genet , vol.8 , pp. 1357-1364
    • Tsai, T.F.1    Jiang, Y.H.2    Bressler, J.3    Armstrong, D.4    Beaudet, A.L.5
  • 68
    • 0033753819 scopus 로고    scopus 로고
    • The 22q11 deletion syndromes
    • Scambler PJ (2000) The 22q11 deletion syndromes. Hum Mol Genet 9: 2421-2426.
    • (2000) Hum Mol Genet , vol.9 , pp. 2421-2426
    • Scambler, P.J.1
  • 69
    • 0033598389 scopus 로고    scopus 로고
    • Congenital heart disease in mice deficient for the DiGeorge syndrome region
    • Lindsay EA, Botta A, Jurecic V, Carattini-Rivera S, Cheah YC, et al. (1999) Congenital heart disease in mice deficient for the DiGeorge syndrome region. Nature 401: 379-383.
    • (1999) Nature , vol.401 , pp. 379-383
    • Lindsay, E.A.1    Botta, A.2    Jurecic, V.3    Carattini-Rivera, S.4    Cheah, Y.C.5
  • 70
    • 0347359152 scopus 로고    scopus 로고
    • Two new mouse chromosome 11 balancers
    • Klysik J, Dinh C, Bradley A (2004) Two new mouse chromosome 11 balancers. Genomics 83: 303-310.
    • (2004) Genomics , vol.83 , pp. 303-310
    • Klysik, J.1    Dinh, C.2    Bradley, A.3
  • 71
    • 0042071270 scopus 로고    scopus 로고
    • Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p
    • Nishijima I, Mills A, Qi Y, Mills M, Bradley A (2003) Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis 36: 142-148.
    • (2003) Genesis , vol.36 , pp. 142-148
    • Nishijima, I.1    Mills, A.2    Qi, Y.3    Mills, M.4    Bradley, A.5
  • 73
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
    • Gu H, Marth JD, Orban PC, Mossmann H, Rajewsky K (1994) Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 265: 103-106.
    • (1994) Science , vol.265 , pp. 103-106
    • Gu, H.1    Marth, J.D.2    Orban, P.C.3    Mossmann, H.4    Rajewsky, K.5
  • 74
    • 2942694533 scopus 로고    scopus 로고
    • A dual role for Hox genes in limb anterior-posterior asymmetry
    • Zakany J, Kmita M, Duboule D (2004) A dual role for Hox genes in limb anterior-posterior asymmetry. Science 304: 1669-1672.
    • (2004) Science , vol.304 , pp. 1669-1672
    • Zakany, J.1    Kmita, M.2    Duboule, D.3
  • 75
    • 16844364675 scopus 로고    scopus 로고
    • E-cadherin intron 2 contains cis-regulatory elements essential for gene expression
    • Stemmler MP, Hecht A, Kemler R (2005) E-cadherin intron 2 contains cis-regulatory elements essential for gene expression. Development 132: 965-976.
    • (2005) Development , vol.132 , pp. 965-976
    • Stemmler, M.P.1    Hecht, A.2    Kemler, R.3
  • 76
    • 0034650804 scopus 로고    scopus 로고
    • Mechanisms of Hox gene colinearity: Transposition of the anterior Hoxb1 gene into the posterior HoxD complex
    • Kmita M, van Der Hoeven F, Zakany J, Krumlauf R, Duboule D (2000) Mechanisms of Hox gene colinearity: Transposition of the anterior Hoxb1 gene into the posterior HoxD complex. Genes Dev 14: 198-211.
    • (2000) Genes Dev , vol.14 , pp. 198-211
    • Kmita, M.1    Van Der Hoeven, F.2    Zakany, J.3    Krumlauf, R.4    Duboule, D.5
  • 77
    • 21344455343 scopus 로고    scopus 로고
    • Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function
    • Kmita M, Tarchini B, Zakany J, Logan M, Tabin CJ, et al. (2005) Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function. Nature 435: 1113-1116.
    • (2005) Nature , vol.435 , pp. 1113-1116
    • Kmita, M.1    Tarchini, B.2    Zakany, J.3    Logan, M.4    Tabin, C.J.5
  • 78
    • 23044477774 scopus 로고    scopus 로고
    • Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes
    • Spitz F, Herkenne C, Morris MA, Duboule D (2005) Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes. Nat Genet 37: 889-893.
    • (2005) Nat Genet , vol.37 , pp. 889-893
    • Spitz, F.1    Herkenne, C.2    Morris, M.A.3    Duboule, D.4
  • 79
    • 1642488879 scopus 로고    scopus 로고
    • Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions
    • U S A
    • Genoud N, Behrens A, Miele G, Robay D, Heppner FL, et al. (2004) Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions. Proc Natl Acad Sci U S A 101: 4198-4203.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 4198-4203
    • Genoud, N.1    Behrens, A.2    Miele, G.3    Robay, D.4    Heppner, F.L.5
  • 80
    • 0037364632 scopus 로고    scopus 로고
    • Cre-mediated germline mosaicism: A new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles
    • Leneuve P, Colnot S, Hamard G, Francis F, Niwa-Kawakita M, et al. (2003) Cre-mediated germline mosaicism: A new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles. Nucleic Acids Res 31: e21.
    • (2003) Nucleic Acids Res , vol.31
    • Leneuve, P.1    Colnot, S.2    Hamard, G.3    Francis, F.4    Niwa-Kawakita, M.5
  • 81
    • 0031040738 scopus 로고    scopus 로고
    • In vivo functional analysis of the Hoxa-1 3′ retinoic acid response element (3′RARE)
    • Dupe V, Davenne M, Brocard J, Dolle P, Mark M, et al. (1997) In vivo functional analysis of the Hoxa-1 3′ retinoic acid response element (3′RARE). Development 124: 399-410.
    • (1997) Development , vol.124 , pp. 399-410
    • Dupe, V.1    Davenne, M.2    Brocard, J.3    Dolle, P.4    Mark, M.5
  • 83
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21: 70-71.
    • (1999) Nat Genet , vol.21 , pp. 70-71
    • Soriano, P.1
  • 85
    • 33744457328 scopus 로고    scopus 로고
    • A deficiency in the region homologous to human 17q21.33-q23.2 causes heart defects in mice
    • Yu YE, Morishima M, Pao A, Wang DY, Wen XY, et al. (2006) A deficiency in the region homologous to human 17q21.33-q23.2 causes heart defects in mice. Genetics 173: 297-307.
    • (2006) Genetics , vol.173 , pp. 297-307
    • Yu, Y.E.1    Morishima, M.2    Pao, A.3    Wang, D.Y.4    Wen, X.Y.5
  • 86
    • 0037079049 scopus 로고    scopus 로고
    • Serial deletions and duplications suggest a mechanism for the collinearity of Hoxd genes in limbs
    • Kmita M, Fraudeau N, Herault Y, Duboule D (2002) Serial deletions and duplications suggest a mechanism for the collinearity of Hoxd genes in limbs. Nature 420: 145-150.
    • (2002) Nature , vol.420 , pp. 145-150
    • Kmita, M.1    Fraudeau, N.2    Herault, Y.3    Duboule, D.4
  • 87
    • 0033667672 scopus 로고    scopus 로고
    • Targeted inversion of a polar silencer within the HoxD complex re-allocates domains of enhancer sharing
    • Kmita M, Kondo T, Duboule D (2000) Targeted inversion of a polar silencer within the HoxD complex re-allocates domains of enhancer sharing. Nat Genet 26: 451-454.
    • (2000) Nat Genet , vol.26 , pp. 451-454
    • Kmita, M.1    Kondo, T.2    Duboule, D.3
  • 88
    • 0036924992 scopus 로고    scopus 로고
    • Evolutionary conserved sequences are required for the insulation of the vertebrate Hoxd complex in neural cells
    • Kmita M, Tarchini B, Duboule D, Herault Y (2002) Evolutionary conserved sequences are required for the insulation of the vertebrate Hoxd complex in neural cells. Development 129: 5521-5528.
    • (2002) Development , vol.129 , pp. 5521-5528
    • Kmita, M.1    Tarchini, B.2    Duboule, D.3    Herault, Y.4
  • 89
    • 0036005808 scopus 로고    scopus 로고
    • A nested deletion approach to generate Cre deleter mice with progressive Hox profiles
    • Herault Y, Kmita M, Sawaya CC, Duboule D (2002) A nested deletion approach to generate Cre deleter mice with progressive Hox profiles. Int J Dev Biol 46: 185-191.
    • (2002) Int J Dev Biol , vol.46 , pp. 185-191
    • Herault, Y.1    Kmita, M.2    Sawaya, C.C.3    Duboule, D.4
  • 90
    • 0041852770 scopus 로고    scopus 로고
    • Microcell-mediated chromosome transfer (MMCT): Small cells with huge potential
    • Doherty AM, Fisher EM (2003) Microcell-mediated chromosome transfer (MMCT): Small cells with huge potential. Mamm Genome 14: 583-592.
    • (2003) Mamm Genome , vol.14 , pp. 583-592
    • Doherty, A.M.1    Fisher, E.M.2
  • 91
    • 27844605427 scopus 로고    scopus 로고
    • The manipulation of chromosomes by mankind: The uses of microcell-mediated chromosome transfer
    • Meaburn KJ, Parris CN, Bridger JM (2005) The manipulation of chromosomes by mankind: The uses of microcell-mediated chromosome transfer. Chromosoma 114: 263-274.
    • (2005) Chromosoma , vol.114 , pp. 263-274
    • Meaburn, K.J.1    Parris, C.N.2    Bridger, J.M.3
  • 92
    • 0033776128 scopus 로고    scopus 로고
    • Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts
    • Kuroiwa Y, Tomizuka K, Shinohara T, Kazuki Y, Yoshida H, et al. (2000) Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts. Nat Biotechnol 18: 1086-1090.
    • (2000) Nat Biotechnol , vol.18 , pp. 1086-1090
    • Kuroiwa, Y.1    Tomizuka, K.2    Shinohara, T.3    Kazuki, Y.4    Yoshida, H.5
  • 93
    • 0042386536 scopus 로고    scopus 로고
    • Telomere-independent homologue pairing and checkpoint escape of accessory ring chromosomes in male mouse meiosis
    • Voet T, Liebe B, Labaere C, Marynen P, Scherthan H (2003) Telomere-independent homologue pairing and checkpoint escape of accessory ring chromosomes in male mouse meiosis. J Cell Biol 162: 795-807.
    • (2003) J Cell Biol , vol.162 , pp. 795-807
    • Voet, T.1    Liebe, B.2    Labaere, C.3    Marynen, P.4    Scherthan, H.5
  • 94
    • 0033976431 scopus 로고    scopus 로고
    • A structurally defined mini-chromosome vector for the mouse germ line
    • Shen MH, Mee PJ, Nichols J, Yang J, Brook F, et al. (2000) A structurally defined mini-chromosome vector for the mouse germ line. Curr Biol 10: 31-34.
    • (2000) Curr Biol , vol.10 , pp. 31-34
    • Shen, M.H.1    Mee, P.J.2    Nichols, J.3    Yang, J.4    Brook, F.5
  • 95
    • 18844424225 scopus 로고    scopus 로고
    • Human artificial chromosome (HAC) vector provides long-term therapeutic transgene expression in normal human primary fibroblasts
    • Kakeda M, Hiratsuka M, Nagata K, Kuroiwa Y, Kakitani M, et al. (2005) Human artificial chromosome (HAC) vector provides long-term therapeutic transgene expression in normal human primary fibroblasts. Gene Ther 12: 852-856.
    • (2005) Gene Ther , vol.12 , pp. 852-856
    • Kakeda, M.1    Hiratsuka, M.2    Nagata, K.3    Kuroiwa, Y.4    Kakitani, M.5
  • 96
    • 0030965015 scopus 로고    scopus 로고
    • Functional expression and germline transmission of a human chromosome fragment in chimaeric mice
    • Tomizuka K, Yoshida H, Uejima H, Kugoh H, Sato K, et al. (1997) Functional expression and germline transmission of a human chromosome fragment in chimaeric mice. Nat Genet 16: 133-143.
    • (1997) Nat Genet , vol.16 , pp. 133-143
    • Tomizuka, K.1    Yoshida, H.2    Uejima, H.3    Kugoh, H.4    Sato, K.5
  • 97
    • 0032925810 scopus 로고    scopus 로고
    • Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21
    • Hernandez D, Mee PJ, Martin JE, Tybulewicz VL, Fisher EM (1999) Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21. Hum Mol Genet 8: 923-933.
    • (1999) Hum Mol Genet , vol.8 , pp. 923-933
    • Hernandez, D.1    Mee, P.J.2    Martin, J.E.3    Tybulewicz, V.L.4    Fisher, E.M.5
  • 98
    • 0034518921 scopus 로고    scopus 로고
    • Stability of transferred human chromosome fragments in cultured cells and in mice
    • Shinohara T, Tomizuka K, Takehara S, Yamauchi K, Katoh M, et al. (2000) Stability of transferred human chromosome fragments in cultured cells and in mice. Chromosome Res 8: 713-725.
    • (2000) Chromosome Res , vol.8 , pp. 713-725
    • Shinohara, T.1    Tomizuka, K.2    Takehara, S.3    Yamauchi, K.4    Katoh, M.5
  • 99
    • 14344275376 scopus 로고    scopus 로고
    • Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome
    • Shinohara T, Tomizuka K, Miyabara S, Takehara S, Kazuki Y, et al. (2001) Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome. Hum Mol Genet 10: 1163-1175.
    • (2001) Hum Mol Genet , vol.10 , pp. 1163-1175
    • Shinohara, T.1    Tomizuka, K.2    Miyabara, S.3    Takehara, S.4    Kazuki, Y.5
  • 100
    • 0034763930 scopus 로고    scopus 로고
    • Germline transmission of a transferred human chromosome 21 fragment in transchromosomal mice
    • Kazuki Y, Shinohara T, Tomizuka K, Katoh M, Ohguma A, et al. (2001) Germline transmission of a transferred human chromosome 21 fragment in transchromosomal mice. J Hum Genet 46: 600-603.
    • (2001) J Hum Genet , vol.46 , pp. 600-603
    • Kazuki, Y.1    Shinohara, T.2    Tomizuka, K.3    Katoh, M.4    Ohguma, A.5
  • 101
    • 25444442381 scopus 로고    scopus 로고
    • An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes
    • O'Doherty A, Ruf S, Mulligan C, Hildreth V, Errington ML, et al. (2005) An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes. Science 309: 2033-2037.
    • (2005) Science , vol.309 , pp. 2033-2037
    • O'Doherty, A.1    Ruf, S.2    Mulligan, C.3    Hildreth, V.4    Errington, M.L.5
  • 102
    • 3042612213 scopus 로고    scopus 로고
    • Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes
    • Olson LE, Roper RJ, Baxter LL, Carlson EJ, Epstein CJ, et al. (2004) Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes. Dev Dyn 230: 581-589.
    • (2004) Dev Dyn , vol.230 , pp. 581-589
    • Olson, L.E.1    Roper, R.J.2    Baxter, L.L.3    Carlson, E.J.4    Epstein, C.J.5
  • 103
    • 33644505833 scopus 로고    scopus 로고
    • Identification of large-scale human-specific copy number differences by inter-species array comparative genomic hybridization
    • Goidts V, Armengol L, Schempp W, Conroy J, Nowak N, et al. (2006) Identification of large-scale human-specific copy number differences by inter-species array comparative genomic hybridization. Hum Genet: 1-14.
    • (2006) Hum Genet , pp. 1-14
    • Goidts, V.1    Armengol, L.2    Schempp, W.3    Conroy, J.4    Nowak, N.5
  • 104
    • 32844460938 scopus 로고    scopus 로고
    • Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans
    • Aitman TJ, Dong R, Vyse TJ, Norsworthy PJ, Johnson MD, et al. (2006) Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. Nature 439: 851-855.
    • (2006) Nature , vol.439 , pp. 851-855
    • Aitman, T.J.1    Dong, R.2    Vyse, T.J.3    Norsworthy, P.J.4    Johnson, M.D.5
  • 107
    • 4444242995 scopus 로고    scopus 로고
    • The European dimension for the mouse genome mutagenesis program
    • Auwerx J, Avner P, Baldock R, Ballabio A, Balling R, et al. (2004) The European dimension for the mouse genome mutagenesis program. Nat Genet 36: 925-927.
    • (2004) Nat Genet , vol.36 , pp. 925-927
    • Auwerx, J.1    Avner, P.2    Baldock, R.3    Ballabio, A.4    Balling, R.5
  • 108
    • 27644576914 scopus 로고    scopus 로고
    • Current issues in mouse genome engineering
    • Glaser S, Anastassiadis K, Stewart AF (2005) Current issues in mouse genome engineering. Nat Genet 37: 1187-1193.
    • (2005) Nat Genet , vol.37 , pp. 1187-1193
    • Glaser, S.1    Anastassiadis, K.2    Stewart, A.F.3
  • 109
    • 14844341770 scopus 로고    scopus 로고
    • Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb
    • Sagai T, Hosoya M, Mizushina Y, Tamura M, Shiroishi T (2005) Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb. Development 132: 797-803.
    • (2005) Development , vol.132 , pp. 797-803
    • Sagai, T.1    Hosoya, M.2    Mizushina, Y.3    Tamura, M.4    Shiroishi, T.5
  • 110
    • 29744447562 scopus 로고    scopus 로고
    • Control of Hoxd genes' collinearity during early limb development
    • Tarchini B, Duboule D (2006) Control of Hoxd genes' collinearity during early limb development. Dev Cell 10: 93-103.
    • (2006) Dev Cell , vol.10 , pp. 93-103
    • Tarchini, B.1    Duboule, D.2
  • 111
    • 2942657608 scopus 로고    scopus 로고
    • Multiple interactions between regulatory regions are required to stabilize an active chromatin hub
    • Patrinos GP, de Krom M, de Boer E, Langeveld A, Imam AM, et al. (2004) Multiple interactions between regulatory regions are required to stabilize an active chromatin hub. Genes Dev 18: 1495-1509.
    • (2004) Genes Dev , vol.18 , pp. 1495-1509
    • Patrinos, G.P.1    De Krom, M.2    De Boer, E.3    Langeveld, A.4    Imam, A.M.5
  • 112
    • 0041534427 scopus 로고    scopus 로고
    • Analysis of a key regulatory region upstream of the Myf5 gene reveals multiple phases of myogenesis, orchestrated at each site by a combination of elements dispersed throughout the locus
    • Hadchouel J, Carvajal JJ, Daubas P, Bajard L, Chang T, et al. (2003) Analysis of a key regulatory region upstream of the Myf5 gene reveals multiple phases of myogenesis, orchestrated at each site by a combination of elements dispersed throughout the locus. Development 130: 3415-3426.
    • (2003) Development , vol.130 , pp. 3415-3426
    • Hadchouel, J.1    Carvajal, J.J.2    Daubas, P.3    Bajard, L.4    Chang, T.5
  • 113
    • 3042740671 scopus 로고    scopus 로고
    • Comparative genomics at the vertebrate extremes
    • Boffelli D, Nobrega MA, Rubin EM (2004) Comparative genomics at the vertebrate extremes. Nat Rev Genet 5: 456-465.
    • (2004) Nat Rev Genet , vol.5 , pp. 456-465
    • Boffelli, D.1    Nobrega, M.A.2    Rubin, E.M.3
  • 114
    • 18744395183 scopus 로고    scopus 로고
    • Numerous potentially functional but non-genic conserved sequences on human chromosome 21
    • Dermitzakis ET, Reymond A, Lyle R, Scamuffa N, Ucla C, et al. (2002) Numerous potentially functional but non-genic conserved sequences on human chromosome 21. Nature 420: 578-582.
    • (2002) Nature , vol.420 , pp. 578-582
    • Dermitzakis, E.T.1    Reymond, A.2    Lyle, R.3    Scamuffa, N.4    Ucla, C.5
  • 115
    • 2442695243 scopus 로고    scopus 로고
    • Comparison of human chromosome 21 conserved nongenic sequences (CNGs) with the mouse and dog genomes shows that their selective constraint is independent of their genic environment
    • Dermitzakis ET, Kirkness E, Schwarz S, Birney E, Reymond A, et al. (2004) Comparison of human chromosome 21 conserved nongenic sequences (CNGs) with the mouse and dog genomes shows that their selective constraint is independent of their genic environment. Genome Res 14: 852-859.
    • (2004) Genome Res , vol.14 , pp. 852-859
    • Dermitzakis, E.T.1    Kirkness, E.2    Schwarz, S.3    Birney, E.4    Reymond, A.5
  • 116
    • 31744448843 scopus 로고    scopus 로고
    • Conserved noncoding sequences are selectively constrained and not mutation cold spots
    • Drake JA, Bird C, Nemesh J, Thomas DJ, Newton-Cheh C, et al. (2006) Conserved noncoding sequences are selectively constrained and not mutation cold spots. Nat Genet 38: 223-227.
    • (2006) Nat Genet , vol.38 , pp. 223-227
    • Drake, J.A.1    Bird, C.2    Nemesh, J.3    Thomas, D.J.4    Newton-Cheh, C.5
  • 117
    • 84882496107 scopus 로고    scopus 로고
    • Genome size evolution in animals
    • Gregory TR, editor. San Diego: Elsevier
    • Gregory TR (2005) Genome size evolution in animals. In: Gregory TR, editor. The evolution of the genome. San Diego: Elsevier. pp. 3-87.
    • (2005) The Evolution of the Genome , pp. 3-87
    • Gregory, T.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.