Embryonic lethality and tumorigenesis caused by segmental aneuploidy on mouse chromosome 11

Genetics

Volumn 150, Issue 3, 1998, Pages 1155-1168

  Liu, Pentao ^a   Zhang, Heju ^a   McLellan, Andrew ^a   Vogel, Hannes ^a   Bradley, Allan ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANEUPLOIDY; ANIMAL CELL; ARTICLE; CARCINOGENESIS; CHROMOSOME 11; CHROMOSOME DUPLICATION; CHROMOSOME INVERSION; CHROMOSOME REARRANGEMENT; EMBRYO; FEMALE; HYPERPLASIA; LETHAL GENE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL; THYMOMA;

ANEUPLOIDY; ANIMALS; CHROMOSOMES; FEMALE; FETAL DEATH; GENETIC MARKERS; HUMANS; MICE; NEOPLASMS; PREGNANCY;

EID: 0031770040     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. AHMAD, K., and K. G. GOLIC, 1996 Somatic reversion of chromosomal position effects in Drosophila melanogaster. Genetics 144: 657-670.
2. ASHBURNER, M., 1989 Drosophila: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
3. BALDINI, A., and E. LINDSAY, 1994 Mapping human YAC clones by fluorescence in situ hybridization using Alu-PCR from single yeast colonies, pp. 75-84 in In Situ Hybridization Protocols, edited by K. H. A. CHOO. Humana Press, Totowa, NJ.
4. BRADLEY, A., 1987 Production and analysis of chimeric mice, pp. 113-151 in Teratocarcinomas and Embryonic Stem Cells - A Practical Approach, edited by E. J. ROBERTSON. IRL, Oxford.
5. BRADLEY, A., and P. LIU, 1996 Target practice in transgenics. Nat. Genet. 14: 121-123.
6. BRIDGES, C. B., 1917 Deficiency. Genetics 2: 445-465.
7. BRIDGES, C. B., 1919 Duplications. Anat. Rec. 15: 357-358.
8. CATTANACH, B. M., M. D. BURTENSHAW, C. RASBERRY and E. P. EVANS, 1993 Large deletions and other gross forms of chromosome imbalance compatible with viability and fertility in the mouse. Nat. Genet. 3: 56-61.
9. CHANCE, P. F., M. K. ALDERSON, K. A. LEPPIG, M. W. LENSCH, N. MATSUNAMI et al., 1993 DNA deletion associated with hereditary neuropathy with liability to pressure palsies. Cell 72: 143-151.
10. CHEN, K.-S., P. MANIAN, T. KOEUTH, L. POTOCKI, Q. ZHAO et al., 1997 Homologous recombination of a flanking repeat gene cluster is a mechanism for a common contiguous gene deletion syndrome. Nat. Genet. 17: 154-163.
11. DIETRICH, W. F., J. MILLER, R. STEEN, M. A. MERCHANT, D. DAMRON-BOLES et al., 1996 A comprehensive genetic map of the mouse genome. Nature 380: 149-152.
12. DRISCOLL, D. A., 1994 Genetic basis of DiGeorge and velocardiofacial syndromes. Curr. Opin. Pediatr. 6: 702-706.
13. EPSTEIN, C. J., 1986 The Consequences of Chromosome Imbalance: Principles, Mechanism, and Models. Cambridge University Press, Cambridge, UK.
14. 2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3. Cell 67: 767-774.
15. FERRARA, N., K. CARVER-MOORE, H. CHEN, M. DOWD, L. LU et al., 1996 Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380: 439-442.
16. FISHER, E., and P. SCAMBLER, 1994 Human haploinsufficiency - one for sorrow, two for joy. Nat. Genet. 7: 5-7.
17. GESSLER, M., K. O. SIMOLA and G. A. BRUNS, 1989 Cloning of breakpoints of a chromosome translocation identifies the AN2 locus. Science 244: 1575-1578.
18. GOLIC, K. G., 1994 Local transposition of P elements in Drosophila melanogaster and recombination between duplicated elements using a site-specific recombinase. Genetics 137: 551-563.
19. GOLIC, K. G., and M. M. GOLIC, 1996 Engineering the Drosophila genome: chromosome rearrangements by design. Genetics 144: 1693-1711.
20. HAKEM, R., J. L. DE LA POMPA, C. SIRARD, R. MO, M. WOO et al., 1996 The tumor suppressor gene Brcal is required for embryonic cellular proliferation in the mouse. Cell 85: 1009-1023.
21. HILL, R. E., J. FAVOR, B. L. HOGAN, C. C. TON, G. F. SAUNDERS et al., 1991 Mouse small eye results from mutations in a paired-like homeobox-containing gene. Nature 354: 522-525.
22. HOLDENER-KENNY, B., S. K. SHARAN and T. MAGNUSON, 1992 Mouse albino-deletions: from genetics to genes in development. Bioessays 14: 831-839.
23. KAUFMAN, M. H., 1992 Atlas of Mouse Development. Academic Press, San Diego.
24. KHALIFA, M. M., P. M. MACLEOD and A. M. DUNCAN, 1993 Additional case of de novo interstitial deletion del(17) (q21.3q23) and expansion of the phenotype. Clin. Genet. 44: 258-261.
25. LAKICH, D., H. H. J. KAZAZIAN, S. E. ANTONARAKIS and J. GITSCHIER, 1993 Inversions disrupting the factor VIII gene are a common cause of severe haemophilia A. Nat. Genet. 5: 236-241.
26. LEVIN, M. L., L. G. SHAFFER, R. A. LEWIS, M. V. GRESIK and J. R. LUPSKI, 1995 Unique de novo interstitial deletion of chromosome 17, del(17) (q23.2q24.3) in a female newborn with multiple congenital anomalies. Am. J. Med. Genet. 55: 30-32.
27. LEWANDOSKI, M., and G. R. MARTIN, 1997 Cre-mediated chromosome loss in mice. Nat. Genet. 17: 223-225.
28. LINDSLEY, D. L., L. SANDLER, B. S. BAKER, A. T. C. CARPENTER, R. E. DENELL et al., 1972 Segmental aneuploidy and the genetic gross structure of the Drosophila genome. Genetics 71: 157-184.
29. LUPSKI, J. R., R. M. DE OCA-LUNA, S. SLAUGENHAUPT, L. PENTAO, V. GUZZETTA et al., 1991 DNA duplication associated with Charcot-Marie-Tooth disease type 1A. Cell 26: 219-232.
30. MARSHALL, C. J., 1991 Tumor suppressor genes. Cell 64: 313-332.
31. MATZUK, M. M., M. J. FINEGOLD, J. G. SU, A. J. HSUEH and A. BRADLEY, 1992 Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice. Nature 360: 313-319.
32. MIKI, Y., J. J. SWENSEN, M. R. HOBBS, B. S. DEHOFF, P. R. ROSTECK et al., 1995 A physical map encompassing GP2B, EPB3, D17S183, D17S78, D17S1183, and D17S1184. Genomics 25: 295-297.
33. PARK, J. P., J. B. MOESCHLER, S. Z. BERG, R. M. BAUER and D. H. WURSTER-HILL, 1992 A unique de novo interstitial deletion del(17)(q21.3q23) in a phenotypically abnormal infant. Clin. Genet. 41: 54-56.
34. POWER, M. A., and P. P. L. TAM, 1993 Onset of gastrulation, morphogenesis and somitogenesis in mouse embryos displaying compensatory growth. Anat. Embryol. 187: 493-504.
35. RABBITTS, T. H., 1994 Chromosomal translocations in human cancer. Nature 372: 143-149.
36. RAMIREZ-SOLIS, R., A. C. DAVIS and A. BRADLEY, 1993 Gene targeting in embryonic stem cells. Methods Enzymol. 225: 855-878.
37. RAMIREZ-SOLIS, R., P. LIU and A. BRADLEY, 1995 Chromosome engineering in mice. Nature 378: 720-724.
38. RINCHIK, E. M., 1991 Chemical mutagenesis and fine-structure functional analysis of the mouse genome. Trends Genet. 7: 15-21.
39. RINCHIK, E. M., and L. B. RUSSELL, 1990 Germ-line deletion mutations in the mouse: Tools for intensive functional and physical mapping of regions of the mammalian genome, pp. 121-159 in Genome Analysis, edited by K. E. DAVIES and S. M. TILGHMAN. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
40. RINCHIK, E., L. FLAHERTY and L. B. RUSSELL, 1993 High-frequency induction of chromosomal rearrangements in mouse germ cells by the chemotherapeutic agent chlorambucil. Bioessays 15: 831-836.
41. ROBERTSON, E. J., 1987 Embryo-derived stem cell lines, pp. 71-112 in Teratocarcinomas and Embryonic Stem Cells - A Practical Approach, edited by E. J. ROBERTSON. IRL, Oxford.
42. SAUER, B., and N. HENDERSON, 1988 Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. Proc. Natl. Acad. Sci. USA 85: 5166-5170.
43. SCHULER, G. D., M. S. BOGUSKI, E. A. STEWART, L. D. STEIN, G. GYAPAY et al., 1996 A gene map of the human genome. Science 274: 540-546.
44. SHARAN, S. K., M. MORIMATSU, U. ALBRECHT, D. S. LIM, E. REGEL et al., 1997 Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2. Nature 386: 804-810.
45. SHUMACHER, A., C. FAUST and T. MAGNUSON, 1996 Positional cloning of a global regulator of anterior-posterior patterning in mice. Nature 383: 250-253.
46. STURTEVANT, A. H., 1926 A crossover reducer in Drosophila melanogaster due to inversion of a section of the third chromosome. Biol. Zentralbl 46: 697-702.
47. TASSABEHJI, M., A. P. READ, V. E. NEWTON, R. HARRIS, R. BALLING et al. 1992 Waardenburg's syndrome patients have mutations in the human homologue of the Pax-3 paired box gene. Nature 355: 635-636.
48. THOMAS, J. W., C. LAMANTIA and T. MAGNUSON, 1998 X-ray-induced mutations in mouse embryonic stem cells. Proc. Natl. Acad. Sci. USA 95: 1114-1119.
49. WATKINS-CHOW, D., M. ROLLER, M. M. NEWHOUSE, A. M. BUCHBERG and S. A. CAMPER, 1996 Mouse chromosome 11. Mamm. Genome 6: 201-220.
50. WEINBERG, R. A., 1991 Tumor suppressor genes. Science 254: 1138-1146.
51. YOU, Y., R. BERGSTROM, M. KLEMM, B. LEDERMAN, H. NELSON et al., 1997 Chromosomal deletion complexes in mice by radiation of embryonic stem cells. Nat. Genet. 15: 285-288.
52. ZHANG, H., P. HASTY and A. BRADLEY, 1994 Targeting frequency for deletion vectors in embryonic stem cells. Mol. Cell. Biol. 14: 2404-2410.