Human artificial chromosome (HAC) vector provides long-term therapeutic transgene expression in normal human primary fibroblasts

Gene Therapy

Volumn 12, Issue 10, 2005, Pages 852-856

  Kakeda, M ^a   Hiratsuka, M ^a,b   Nagata, K ^a   Kuroiwa, Y ^a   Kakitani, M ^a   Katoh, M ^b   Oshimura, M ^b   Tomizuka, K ^a,b  

^a KIRIN BREWERY CO LTD   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

Author keywords

Erythropoietin (EPO); Human artificial chromosome (HAC); Microcell mediated chromosome transfer (MMCT); Normal primary fibroblasts; Transgene expression

Indexed keywords

ERYTHROPOIETIN;

ARTICLE; ARTIFICIAL CHROMOSOME; CHROMOSOME STRUCTURE; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; CYTOGENETICS; EXPRESSION VECTOR; FIBROBLAST; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; HUMAN; HUMAN CELL; NONVIRAL GENE DELIVERY SYSTEM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TRANSGENE;

CELLS, CULTURED; CHROMOSOMES, ARTIFICIAL, HUMAN; ERYTHROPOIETIN; FIBROBLASTS; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; HUMANS; TIME FACTORS; TRANSDUCTION, GENETIC; TRANSGENES;

EID: 18844424225     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302483     Document Type: Article

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