Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations

Genes and Development

Volumn 15, Issue 17, 2001, Pages 2209-2214

  Spitz, François ^a   Gonzalez, Federico ^a   Peichel, Catherine ^b,c   Vogt, Thomas F ^b,d   Duboule, Denis ^a   Zákány, József ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b PRINCETON UNIVERSITY   (United States)

^c STANFORD UNIVERSITY   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

BAC; Colinearity; Hox cluster; Remote enhancers

Indexed keywords

ARTICLE; GENE CLUSTER; GENE DELETION; GROWTH REGULATION; HUMAN; LIMB DEVELOPMENT; MOLECULAR EVOLUTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; BONE DEVELOPMENT; DNA-BINDING PROTEINS; EMBRYO; EVOLUTION, MOLECULAR; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; HOMEODOMAIN PROTEINS; HUMANS; IN SITU HYBRIDIZATION; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; MODELS, GENETIC; MULTIGENE FAMILY; MUTATION; NEOPLASM PROTEINS; PHENOTYPE; RECOMBINATION, GENETIC; TIME FACTORS; TRANSCRIPTION FACTORS;

MAMMALIA; MURINAE; MUS MUSCULUS; VERTEBRATA;

EID: 0035448880     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.205701     Document Type: Article

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