-
1
-
-
12344335482
-
Long-lived growth hormone receptor knockout mice: Interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction
-
Al-Regaiey KA, Masternak MM, Bonkowski M, Sun L, and Bartke A. Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction. Endocrinology 146: 851-860, 2005.
-
(2005)
Endocrinology
, vol.146
, pp. 851-860
-
-
Al-Regaiey, K.A.1
Masternak, M.M.2
Bonkowski, M.3
Sun, L.4
Bartke, A.5
-
2
-
-
0031984952
-
Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats
-
Anai M, Funaki M, Ogihara T, Terasaki J, Inukai K, Katagiri H, Fukushima Y, Yazaki Y, Kikuchi M, Oka Y, and Asano T. Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats. Diabetes 47: 13-23, 1998.
-
(1998)
Diabetes
, vol.47
, pp. 13-23
-
-
Anai, M.1
Funaki, M.2
Ogihara, T.3
Terasaki, J.4
Inukai, K.5
Katagiri, H.6
Fukushima, Y.7
Yazaki, Y.8
Kikuchi, M.9
Oka, Y.10
Asano, T.11
-
3
-
-
0015288981
-
Respiratory capacity of white, red, and intermediate muscle: Adaptive response to exercise
-
Baldwin KM, Klinkerfuss GH, Terjung RL, Mole PA, and Holloszy JO. Respiratory capacity of white, red, and intermediate muscle: adaptive response to exercise. Am J Physiol 222: 373-378, 1972.
-
(1972)
Am J Physiol
, vol.222
, pp. 373-378
-
-
Baldwin, K.M.1
Klinkerfuss, G.H.2
Terjung, R.L.3
Mole, P.A.4
Holloszy, J.O.5
-
4
-
-
0014798968
-
Effect of exercise on skeletal muscle. I. Biochemical and histochemical properties
-
Barnard RJ, Edgerton VR, and Peter JB. Effect of exercise on skeletal muscle. I. Biochemical and histochemical properties. J Appl Physiol 28: 762-766, 1970.
-
(1970)
J Appl Physiol
, vol.28
, pp. 762-766
-
-
Barnard, R.J.1
Edgerton, V.R.2
Peter, J.B.3
-
5
-
-
0037977708
-
Skeletal muscle sterol regulatory element binding protein-1c decreases with food deprivation and increases with feeding in rats
-
Bizeau ME, MacLean PS, Johnson GC, and Wei Y. Skeletal muscle sterol regulatory element binding protein-1c decreases with food deprivation and increases with feeding in rats. J Nutr 133: 1787-1792, 2003.
-
(2003)
J Nutr
, vol.133
, pp. 1787-1792
-
-
Bizeau, M.E.1
MacLean, P.S.2
Johnson, G.C.3
Wei, Y.4
-
6
-
-
0021321296
-
Effects of physical training and diet therapy on carbohydrate metabolism in patients with glucose intolerance and non-insulin-dependent diabetes mellitus
-
Bogardus C, Ravussin E, Robbins DC, Wolfe RR, Horton ES, and Sims EA. Effects of physical training and diet therapy on carbohydrate metabolism in patients with glucose intolerance and non-insulin-dependent diabetes mellitus. Diabetes 33: 311-318, 1984.
-
(1984)
Diabetes
, vol.33
, pp. 311-318
-
-
Bogardus, C.1
Ravussin, E.2
Robbins, D.C.3
Wolfe, R.R.4
Horton, E.S.5
Sims, E.A.6
-
7
-
-
0032582685
-
Obesity-related overexpression of fatty-acid synthase gene in adipose tissue involves sterol regulatory element-binding protein transcription factors
-
Boizard M, Liepvre X, Lemarchand P, Foufelle F, Ferre P, and Dugail I. Obesity-related overexpression of fatty-acid synthase gene in adipose tissue involves sterol regulatory element-binding protein transcription factors. J Biol Chem 273: 29164-29171, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 29164-29171
-
-
Boizard, M.1
Liepvre, X.2
Lemarchand, P.3
Foufelle, F.4
Ferre, P.5
Dugail, I.6
-
8
-
-
0038321436
-
Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes
-
Bouzakri K, Roques M, Gual P, Espinosa S, Guebre-Egziabher F, Riou JP, Laville M, Le Marchand-Brustel Y, Tanti JF, and Vidal H. Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes. Diabetes 52: 1319-1325, 2003.
-
(2003)
Diabetes
, vol.52
, pp. 1319-1325
-
-
Bouzakri, K.1
Roques, M.2
Gual, P.3
Espinosa, S.4
Guebre-Egziabher, F.5
Riou, J.P.6
Laville, M.7
Le Marchand-Brustel, Y.8
Tanti, J.F.9
Vidal, H.10
-
9
-
-
0345708299
-
Exercise training preserves coronary flow and reduces infarct size after ischemia-reperfusion in rat heart
-
Brown DA, Jew KN, Sparagna GC, Musch TI, and Moore RL. Exercise training preserves coronary flow and reduces infarct size after ischemia-reperfusion in rat heart. J Appl Physiol 95: 2510-2518, 2003.
-
(2003)
J Appl Physiol
, vol.95
, pp. 2510-2518
-
-
Brown, D.A.1
Jew, K.N.2
Sparagna, G.C.3
Musch, T.I.4
Moore, R.L.5
-
10
-
-
29244453622
-
Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat
-
Brown DA, Chicco AJ, Jew KN, Johnson MS, Lynch JM, Watson PA, and Moore RL. Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat. J Physiol 569: 913-924, 2005.
-
(2005)
J Physiol
, vol.569
, pp. 913-924
-
-
Brown, D.A.1
Chicco, A.J.2
Jew, K.N.3
Johnson, M.S.4
Lynch, J.M.5
Watson, P.A.6
Moore, R.L.7
-
11
-
-
0030941803
-
The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
Brown M and Goldstein JL. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89: 331-340, 1997.
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Brown, M.1
Goldstein, J.L.2
-
12
-
-
3042846012
-
In vivo regulation of SREBP-1c in skeletal muscle: Effects of nutritional status, glucose, insulin, and leptin
-
Commerford SR, Peng L, Dube JJ, and O'Doherty RM. In vivo regulation of SREBP-1c in skeletal muscle: effects of nutritional status, glucose, insulin, and leptin. Am J Physiol Regul Integr Comp Physiol 287: R218-R227, 2004.
-
(2004)
Am J Physiol Regul Integr Comp Physiol
, vol.287
-
-
Commerford, S.R.1
Peng, L.2
Dube, J.J.3
O'Doherty, R.M.4
-
13
-
-
0036298761
-
Muscle long-chain acyl CoA esters and insulin resistance
-
Cooney GJ, Thompson AL, Furler SM, Ye J, and Kraegen EW. Muscle long-chain acyl CoA esters and insulin resistance. Ann NY Acad Sci 967: 196-207, 2002.
-
(2002)
Ann NY Acad Sci
, vol.967
, pp. 196-207
-
-
Cooney, G.J.1
Thompson, A.L.2
Furler, S.M.3
Ye, J.4
Kraegen, E.W.5
-
14
-
-
0033968126
-
Insulin resistance differentially affects the PI3-kinase- and MAP-kinase-mediated signalling in human muscle
-
Cusi K, Maezono K, Osman A, Pendergrass M, Patti ME, Pratipanawatr T, DeFronzo RA, Kahn CR, and Mandarino LJ. Insulin resistance differentially affects the PI3-kinase- and MAP-kinase-mediated signalling in human muscle. J Clin Invest 105: 311-320, 2000.
-
(2000)
J Clin Invest
, vol.105
, pp. 311-320
-
-
Cusi, K.1
Maezono, K.2
Osman, A.3
Pendergrass, M.4
Patti, M.E.5
Pratipanawatr, T.6
Defronzo, R.A.7
Kahn, C.R.8
Mandarino, L.J.9
-
15
-
-
0023604784
-
Effect of physical training on insulin action in obesity
-
DeFronzo RA, Sherwin RS, and Kraemer N. Effect of physical training on insulin action in obesity. Diabetes 36: 1379-1385, 1987.
-
(1987)
Diabetes
, vol.36
, pp. 1379-1385
-
-
DeFronzo, R.A.1
Sherwin, R.S.2
Kraemer, N.3
-
16
-
-
0030017441
-
Training-induced enhancement of insulin action in human skeletal muscle: The influence of aging
-
Dela F, Mikines KJ, Larsen JJ, and Galbo H. Training-induced enhancement of insulin action in human skeletal muscle: the influence of aging. J Gerontol A Biol Sci Med Sci 51: B247-B252, 1996.
-
(1996)
J Gerontol A Biol Sci Med Sci
, vol.51
-
-
Dela, F.1
Mikines, K.J.2
Larsen, J.J.3
Galbo, H.4
-
17
-
-
24644463295
-
Schoenheimer effect explained - Feedback regulation of cholesterol synthesis in mice mediated by Insig proteins
-
Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, and Brown MS. Schoenheimer effect explained - feedback regulation of cholesterol synthesis in mice mediated by Insig proteins. J Clin Invest 115: 2489-2498, 2005.
-
(2005)
J Clin Invest
, vol.115
, pp. 2489-2498
-
-
Engelking, L.J.1
Liang, G.2
Hammer, R.E.3
Takaishi, K.4
Kuriyama, H.5
Evers, B.M.6
Li, W.P.7
Horton, J.D.8
Goldstein, J.L.9
Brown, M.S.10
-
18
-
-
0023868703
-
Carbohydrate and lipid metabolism of skeletal muscle in type 2 diabetic patients
-
Falholt K, Jensen I, Lindkaer Jensen S, Mortensen H, Volund A, Heding LG, Noerskov Petersen P, and Falholt W. Carbohydrate and lipid metabolism of skeletal muscle in type 2 diabetic patients. Diabet Med 5: 27-31, 1988.
-
(1988)
Diabet Med
, vol.5
, pp. 27-31
-
-
Falholt, K.1
Jensen, I.2
Lindkaer Jensen, S.3
Mortensen, H.4
Volund, A.5
Heding, L.G.6
Noerskov Petersen, P.7
Falholt, W.8
-
19
-
-
0027484001
-
Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus
-
Folli F, Saad MJ, Backer JM, and Kahn CR. Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus. J Clin Invest 92: 1787-1794, 1993.
-
(1993)
J Clin Invest
, vol.92
, pp. 1787-1794
-
-
Folli, F.1
Saad, M.J.2
Backer, J.M.3
Kahn, C.R.4
-
20
-
-
0033607176
-
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
-
Foretz M, Guichard C, Ferre P, and Foufelle F. Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes. Proc Natl Acad Sci USA 96: 12737-12742, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12737-12742
-
-
Foretz, M.1
Guichard, C.2
Ferre, P.3
Foufelle, F.4
-
21
-
-
0035217707
-
Skeletal muscle lipid content and insulin resistance: Evidence for a paradox in endurance-trained athletes
-
Goodpaster BH, He J, Watkins S, and Kelley DE. Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes. J Clin Endocrinol Metab 86: 5755-5761, 2001.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 5755-5761
-
-
Goodpaster, B.H.1
He, J.2
Watkins, S.3
Kelley, D.E.4
-
22
-
-
0030765908
-
Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat
-
Goodpaster BH, Thaete FL, Simoneau JA, and Kelley DE. Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes 46: 1579-1585, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 1579-1585
-
-
Goodpaster, B.H.1
Thaete, F.L.2
Simoneau, J.A.3
Kelley, D.E.4
-
23
-
-
0036097562
-
Insulin resistance in morbid obesity: Reversal with intramyocellular fat depletion
-
Greco AV, Mingrone G, Giancaterini A, Manco M, Morroni M, Cinti S, Granzotto M, Vettor R, Camastra S, and Ferrannini E. Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion. Diabetes 51: 144-151, 2002.
-
(2002)
Diabetes
, vol.51
, pp. 144-151
-
-
Greco, A.V.1
Mingrone, G.2
Giancaterini, A.3
Manco, M.4
Morroni, M.5
Cinti, S.6
Granzotto, M.7
Vettor, R.8
Camastra, S.9
Ferrannini, E.10
-
24
-
-
0036259860
-
Sterol regulatory element binding protein-1c expression and action in rat muscles
-
Guillet-Deniau I, Mieulet V, Lay SL, Achouri Y, Carre D, Girard J, Foufelle F, and Ferre P. Sterol regulatory element binding protein-1c expression and action in rat muscles. Diabetes 51: 1722-1728, 2002.
-
(2002)
Diabetes
, vol.51
, pp. 1722-1728
-
-
Guillet-Deniau, I.1
Mieulet, V.2
Lay, S.L.3
Achouri, Y.4
Carre, D.5
Girard, J.6
Foufelle, F.7
Ferre, P.8
-
25
-
-
0029366031
-
Prevention of obesity in middle-aged monkeys: Food intake during body weight clamp
-
Hansen BC, Ortmeyer HK, and Bodkin NL. Prevention of obesity in middle-aged monkeys: food intake during body weight clamp. Obes Res 3, Suppl 2: 199s-204s, 1995.
-
(1995)
Obes Res
, vol.3
, Issue.2 SUPPL.
-
-
Hansen, B.C.1
Ortmeyer, H.K.2
Bodkin, N.L.3
-
26
-
-
0014198263
-
Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle
-
Holloszy JO. Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle. J Biol Chem 242: 2278-2282, 1967.
-
(1967)
J Biol Chem
, vol.242
, pp. 2278-2282
-
-
Holloszy, J.O.1
-
27
-
-
0022260872
-
Endurance training in humans: Aerobic capacity and structure of skeletal muscle
-
Hoppeler H, Howald H, Conley K, Lindstedt SL, Claassen H, Vock P, and Weibel ER. Endurance training in humans: aerobic capacity and structure of skeletal muscle. J Appl Physiol 59: 320-327, 1985.
-
(1985)
J Appl Physiol
, vol.59
, pp. 320-327
-
-
Hoppeler, H.1
Howald, H.2
Conley, K.3
Lindstedt, S.L.4
Claassen, H.5
Vock, P.6
Weibel, E.R.7
-
28
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton J, Goldstein JL, and Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 109: 1125-1131, 2002.
-
(2002)
J Clin Invest
, vol.109
, pp. 1125-1131
-
-
Horton, J.1
Goldstein, J.L.2
Brown, M.S.3
-
29
-
-
2942735492
-
The molecular mechanism linking muscle fat accumulation to insulin resistance
-
Hulver MW and Dohm GL. The molecular mechanism linking muscle fat accumulation to insulin resistance. Proc Nutr Soc 63: 375-380, 2004.
-
(2004)
Proc Nutr Soc
, vol.63
, pp. 375-380
-
-
Hulver, M.W.1
Dohm, G.L.2
-
30
-
-
0034682474
-
Leptin, troglitazone, and the expression of sterol regulatory element binding protein in liver and pancreatic islets
-
Kakuma T, Lee Y, Higa M, Wang Z, Pan W, Shimomura I, and Unger RH. Leptin, troglitazone, and the expression of sterol regulatory element binding protein in liver and pancreatic islets. Proc Natl Acad Sci USA 97: 8536-8541, 2000.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 8536-8541
-
-
Kakuma, T.1
Lee, Y.2
Higa, M.3
Wang, Z.4
Pan, W.5
Shimomura, I.6
Unger, R.H.7
-
31
-
-
0037312801
-
Increased intramyocellular lipid concentration identifies impaired glucose metabolism in women with previous gestational diabetes
-
Kautzky-Willer A, Krssak M, Winzer C, Pacini G, Tura A, Farhan S, Wagner O, Brabant G, Horn R, Stingl H, Schneider B, Waldhausl W, and Roden M. Increased intramyocellular lipid concentration identifies impaired glucose metabolism in women with previous gestational diabetes. Diabetes 52: 244-251, 2003.
-
(2003)
Diabetes
, vol.52
, pp. 244-251
-
-
Kautzky-Willer, A.1
Krssak, M.2
Winzer, C.3
Pacini, G.4
Tura, A.5
Farhan, S.6
Wagner, O.7
Brabant, G.8
Horn, R.9
Stingl, H.10
Schneider, B.11
Waldhausl, W.12
Roden, M.13
-
32
-
-
2642683510
-
Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse
-
Kerouz N, Horsch D, Pons S, and Kahn CR. Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse. J Clin Invest 100: 3164-3172, 1997.
-
(1997)
J Clin Invest
, vol.100
, pp. 3164-3172
-
-
Kerouz, N.1
Horsch, D.2
Pons, S.3
Kahn, C.R.4
-
33
-
-
0027214460
-
Skeletal muscle substrate utilization during submaximal exercise in man: Effect of endurance training
-
Kiens B, Essen-Gustavsson B, Christensen NJ, and Saltin B. Skeletal muscle substrate utilization during submaximal exercise in man: effect of endurance training. J Physiol 469: 459-478, 1993.
-
(1993)
J Physiol
, vol.469
, pp. 459-478
-
-
Kiens, B.1
Essen-Gustavsson, B.2
Christensen, N.J.3
Saltin, B.4
-
34
-
-
0031963963
-
Nutritional and insulin regulation of fatty acid synthase and leptin gene expression through ADD1/SREBP1
-
Kim J, Sarraf P, Wright M, Yao KM, Meuller E, Solanes G, Lowell BB, and Spiegelman B. Nutritional and insulin regulation of fatty acid synthase and leptin gene expression through ADD1/SREBP1. J Clin Invest 101: 1-9, 1998.
-
(1998)
J Clin Invest
, vol.101
, pp. 1-9
-
-
Kim, J.1
Sarraf, P.2
Wright, M.3
Yao, K.M.4
Meuller, E.5
Solanes, G.6
Lowell, B.B.7
Spiegelman, B.8
-
35
-
-
0032698470
-
Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes
-
Kim Y, Nikoulina SE, Ciaraldi TP, Henry RR, and Kahn BB. Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes. J Clin Invest 104: 733-741, 1999.
-
(1999)
J Clin Invest
, vol.104
, pp. 733-741
-
-
Kim, Y.1
Nikoulina, S.E.2
Ciaraldi, T.P.3
Henry, R.R.4
Kahn, B.B.5
-
36
-
-
0343851602
-
Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade
-
Kotzka J, Muller-Wieland D, Roth G, Kremer L, Munck M, Schurmann S, Knebel B, and Krone W. Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade. J Lipid Res 41: 99-108, 2000.
-
(2000)
J Lipid Res
, vol.41
, pp. 99-108
-
-
Kotzka, J.1
Muller-Wieland, D.2
Roth, G.3
Kremer, L.4
Munck, M.5
Schurmann, S.6
Knebel, B.7
Krone, W.8
-
37
-
-
0343314906
-
Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients
-
Krook A, Bjornholm M, Galuska D, Jiang XJ, Fahlman R, Myers MG Jr, Wallberg-Henriksson H, and Zierath JR. Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients. Diabetes 49: 284-292, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 284-292
-
-
Krook, A.1
Bjornholm, M.2
Galuska, D.3
Jiang, X.J.4
Fahlman, R.5
Myers Jr., M.G.6
Wallberg-Henriksson, H.7
Zierath, J.R.8
-
38
-
-
0032934826
-
Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: A 1H NMR spectroscopy study
-
Krssak M, Falk Petersen K, Dresner A, DiPietro L, Vogel SM, Rothman DL, Roden M, and Shulman GI. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia 42: 113-116, 1999.
-
(1999)
Diabetologia
, vol.42
, pp. 113-116
-
-
Krssak, M.1
Falk Petersen, K.2
Dresner, A.3
DiPietro, L.4
Vogel, S.M.5
Rothman, D.L.6
Roden, M.7
Shulman, G.I.8
-
39
-
-
0037219256
-
Intramyocellular lipid and insulin resistance
-
Kuhlmann J, Neumann-Haeflein C, Belz U, Kalisch J, Juretschke H, Stein M, Kleinschmidt E, Kramer W, and Herling A. Intramyocellular lipid and insulin resistance. Diabetes 52: 138-144, 2003.
-
(2003)
Diabetes
, vol.52
, pp. 138-144
-
-
Kuhlmann, J.1
Neumann-Haeflein, C.2
Belz, U.3
Kalisch, J.4
Juretschke, H.5
Stein, M.6
Kleinschmidt, E.7
Kramer, W.8
Herling, A.9
-
40
-
-
0033399406
-
Muscle lipid accumulation and protein kinase C activation in the insulin-resistant chronically glucose-infused rat
-
Laybutt DR, Schmitz-Peiffer C, Saha AK, Ruderman NB, Biden TJ, and Kraegen EW. Muscle lipid accumulation and protein kinase C activation in the insulin-resistant chronically glucose-infused rat. Am J Physiol Endocrinol Metab 277: E1070-E1076, 1999.
-
(1999)
Am J Physiol Endocrinol Metab
, vol.277
-
-
Laybutt, D.R.1
Schmitz-Peiffer, C.2
Saha, A.K.3
Ruderman, N.B.4
Biden, T.J.5
Kraegen, E.W.6
-
41
-
-
12344305124
-
Mitochondrial dysfunction and type 2 diabetes
-
Lowell BB and Shulman GI. Mitochondrial dysfunction and type 2 diabetes. Science 307: 384-387, 2005.
-
(2005)
Science
, vol.307
, pp. 384-387
-
-
Lowell, B.B.1
Shulman, G.I.2
-
42
-
-
0015158588
-
Adaptation of muscle to exercise. Increase in levels of palmityl CoA synthetase, carnitine palmityltransferase and palmityl CoA dehydrogenase and in the capacity to oxidize fatty acids
-
Mole PA, Oscai LB, and Holloszy JO. Adaptation of muscle to exercise. Increase in levels of palmityl CoA synthetase, carnitine palmityltransferase and palmityl CoA dehydrogenase and in the capacity to oxidize fatty acids. J Clin Invest 50: 2323-2330, 1971.
-
(1971)
J Clin Invest
, vol.50
, pp. 2323-2330
-
-
Mole, P.A.1
Oscai, L.B.2
Holloszy, J.O.3
-
43
-
-
0014445091
-
Effect of long-term exercise on skeletal muscle lipid composition
-
Morgan TE, Short FA, and Cobb LA. Effect of long-term exercise on skeletal muscle lipid composition. Am J Physiol 216: 82-86, 1969.
-
(1969)
Am J Physiol
, vol.216
, pp. 82-86
-
-
Morgan, T.E.1
Short, F.A.2
Cobb, L.A.3
-
44
-
-
0002736640
-
Effects of long-term exercise on human muscle mitochondria
-
edited by Pernow B and Saltin B. New York: Plenum
-
Morgan TE, Cobb LA, Short FA, Ross R, and Gun DR. Effects of long-term exercise on human muscle mitochondria. In: Muscle Metabolism During Exercise, edited by Pernow B and Saltin B. New York: Plenum, 1971, p. 87-95.
-
(1971)
Muscle Metabolism during Exercise
, pp. 87-95
-
-
Morgan, T.E.1
Cobb, L.A.2
Short, F.A.3
Ross, R.4
Gun, D.R.5
-
45
-
-
4544243217
-
Insulin regulation of SREBP-1 expression in L-6 muscle cells and 3T3 L1 adipocytes
-
Nadeau K, Leitner JW, Gurerich I, and Draznin B. Insulin regulation of SREBP-1 expression in L-6 muscle cells and 3T3 L1 adipocytes. J Biol Chem 279: 34380-34387, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 34380-34387
-
-
Nadeau, K.1
Leitner, J.W.2
Gurerich, I.3
Draznin, B.4
-
47
-
-
33745806981
-
Chronic calorie restriction prevents obesity-associated increases in liver triglyceride (TG), but not age-related increases in muscle triglyceride
-
Ortmeyer HK, Collins C, Tison A, Goldberg AP, and Hansen BC. Chronic calorie restriction prevents obesity-associated increases in liver triglyceride (TG), but not age-related increases in muscle triglyceride (Abstract). FASEB J 18: A95, 2004.
-
(2004)
FASEB J
, vol.18
-
-
Ortmeyer, H.K.1
Collins, C.2
Tison, A.3
Goldberg, A.P.4
Hansen, B.C.5
-
48
-
-
0030969532
-
Skeletal muscle triglyceride levels are inversely related to insulin action
-
Pan DA, Lillioja S, Kriketos AD, Milner MR, Baur LA, Bogardus C, Jenkins AB, and Storlien LH. Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes 46: 983-988, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 983-988
-
-
Pan, D.A.1
Lillioja, S.2
Kriketos, A.D.3
Milner, M.R.4
Baur, L.A.5
Bogardus, C.6
Jenkins, A.B.7
Storlien, L.H.8
-
49
-
-
3042551249
-
Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation
-
Perdomo G, Commerford SR, Richard AM, Adams SH, Corkey BE, O'Doherty RM, and Brown NF. Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation. J Biol Chem 279: 27177-27186, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 27177-27186
-
-
Perdomo, G.1
Commerford, S.R.2
Richard, A.M.3
Adams, S.H.4
Corkey, B.E.5
O'Doherty, R.M.6
Brown, N.F.7
-
50
-
-
0032764784
-
Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: A 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents
-
Perseghin G, Scifo P, De Cobelli F, Pagliato E, Battezzati A, Arcelloni C, Vanzulli A, Testolin G, Pozza G, Del Maschio A, and Luzi L. Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. Diabetes 48: 1600-1606, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 1600-1606
-
-
Perseghin, G.1
Scifo, P.2
De Cobelli, F.3
Pagliato, E.4
Battezzati, A.5
Arcelloni, C.6
Vanzulli, A.7
Testolin, G.8
Pozza, G.9
Del Maschio, A.10
Luzi, L.11
-
51
-
-
1642377274
-
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
-
Petersen KF, Dufour S, Befroy D, Garcia R, and Shulman GI. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med 350: 664-671, 2004.
-
(2004)
N Engl J Med
, vol.350
, pp. 664-671
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
Garcia, R.4
Shulman, G.I.5
-
52
-
-
0029787329
-
Intramuscular triglyceride and muscle insulin sensitivity: Evidence for a relationship in nondiabetic subjects
-
Phillips DI, Caddy S, Ilic V, Fielding BA, Frayn KN, Borthwick AC, and Taylor R. Intramuscular triglyceride and muscle insulin sensitivity: evidence for a relationship in nondiabetic subjects. Metabolism 45: 947-950, 1996.
-
(1996)
Metabolism
, vol.45
, pp. 947-950
-
-
Phillips, D.I.1
Caddy, S.2
Ilic, V.3
Fielding, B.A.4
Frayn, K.N.5
Borthwick, A.C.6
Taylor, R.7
-
53
-
-
6044224890
-
Exercise training increases intramyocellular lipid and oxidative capacity in older adults
-
Pruchnic R, Katsiaras A, He J, Kelley DE, Winters C, and Goodpaster BH. Exercise training increases intramyocellular lipid and oxidative capacity in older adults. Am J Physiol Endocrinol Metab 287: E857-E862, 2004.
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
-
-
Pruchnic, R.1
Katsiaras, A.2
He, J.3
Kelley, D.E.4
Winters, C.5
Goodpaster, B.H.6
-
54
-
-
17444420663
-
Pioglitazone improves insulin sensitivity through reduction in muscle lipid and redistribution of lipid into adipose tissue
-
Rasouli N, Raue U, Miles LM, Lu T, Di Gregorio GB, Elbein SC, and Kern PA. Pioglitazone improves insulin sensitivity through reduction in muscle lipid and redistribution of lipid into adipose tissue. Am J Physiol Endocrinol Metab 288: E930-E934, 2005.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
-
-
Rasouli, N.1
Raue, U.2
Miles, L.M.3
Lu, T.4
Di Gregorio, G.B.5
Elbein, S.C.6
Kern, P.A.7
-
55
-
-
12144275294
-
Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes
-
Ritov VB, Menshikova EV, He J, Ferrell RE, Goodpaster BH, and Kelley DE. Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes. Diabetes 54: 8-14, 2005.
-
(2005)
Diabetes
, vol.54
, pp. 8-14
-
-
Ritov, V.B.1
Menshikova, E.V.2
He, J.3
Ferrell, R.E.4
Goodpaster, B.H.5
Kelley, D.E.6
-
56
-
-
0033977188
-
Effect of contraction on mitogen-activated protein kinase signal transduction in skeletal muscle. Involvement of the mitogen- and stress-activated protein kinase 1
-
Ryder JW, Fahlman R, Wallberg-Henriksson H, Alessi DR, Krook A, and Zierath JR. Effect of contraction on mitogen-activated protein kinase signal transduction in skeletal muscle. Involvement Of the mitogen- and stress-activated protein kinase 1. J Biol Chem 275: 1457-1462, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 1457-1462
-
-
Ryder, J.W.1
Fahlman, R.2
Wallberg-Henriksson, H.3
Alessi, D.R.4
Krook, A.5
Zierath, J.R.6
-
57
-
-
0033749620
-
Signalling aspects of insulin resistance in skeletal muscle: Mechanisms induced by lipid oversupply
-
Schmitz-Peiffer C. Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply. Cell Signal 12: 583-594, 2000.
-
(2000)
Cell Signal
, vol.12
, pp. 583-594
-
-
Schmitz-Peiffer, C.1
-
58
-
-
0343890977
-
Synthesis and destruction of cholesterol in the organism
-
Schoenheimer R and Breusch F. Synthesis and destruction of cholesterol in the organism. J Biol Chem 103: 439-448, 1933.
-
(1933)
J Biol Chem
, vol.103
, pp. 439-448
-
-
Schoenheimer, R.1
Breusch, F.2
-
59
-
-
0036228456
-
Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-alpha
-
Sewter C, Berger D, Considine RV, Medina G, Rochford J, Ciaraldi T, Henry R, Dohm L, Flier JS, O'Rahilly S, and Vidal-Puig AJ. Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-alpha. Diabetes 51: 1035-1041, 2002.
-
(2002)
Diabetes
, vol.51
, pp. 1035-1041
-
-
Sewter, C.1
Berger, D.2
Considine, R.V.3
Medina, G.4
Rochford, J.5
Ciaraldi, T.6
Henry, R.7
Dohm, L.8
Flier, J.S.9
O'Rahilly, S.10
Vidal-Puig, A.J.11
-
60
-
-
0033570119
-
Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus
-
Shimomura I, Bashkamov Y, and Horton JD. Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus. J Biol Chem 274: 30028-30032, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 30028-30032
-
-
Shimomura, I.1
Bashkamov, Y.2
Horton, J.D.3
-
61
-
-
77957010982
-
Citrate synthase
-
Srere P. Citrate synthase. Methods Enzymol 13: 3-5, 1969.
-
(1969)
Methods Enzymol
, vol.13
, pp. 3-5
-
-
Srere, P.1
-
62
-
-
0036787463
-
Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota
-
Standaert ML, Ortmeyer HK, Sajan MP, Kanoh Y, Bandyopadhyay G, Hansen BC, and Farese RV. Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota. Diabetes 51: 2936-2943, 2002.
-
(2002)
Diabetes
, vol.51
, pp. 2936-2943
-
-
Standaert, M.L.1
Ortmeyer, H.K.2
Sajan, M.P.3
Kanoh, Y.4
Bandyopadhyay, G.5
Hansen, B.C.6
Farese, R.V.7
-
63
-
-
0018827012
-
Muscle triglycerides in diabetic subjects. Effect of insulin deficiency and exercise
-
Standl E, Lotz N, Dexel T, Janka HU, and Kolb HJ. Muscle triglycerides in diabetic subjects. Effect of insulin deficiency and exercise. Diabetologia 18: 463-469, 1980.
-
(1980)
Diabetologia
, vol.18
, pp. 463-469
-
-
Standl, E.1
Lotz, N.2
Dexel, T.3
Janka, H.U.4
Kolb, H.J.5
-
64
-
-
4644227798
-
Tissue-specific effect of refeeding after short- and long-term caloric restriction on malic enzyme gene expression in rat tissues
-
Stelmanska E, Korczynska J, and Swierczynski J. Tissue-specific effect of refeeding after short- and long-term caloric restriction on malic enzyme gene expression in rat tissues. Acta Biochim Pol 51: 805-814, 2004.
-
(2004)
Acta Biochim Pol
, vol.51
, pp. 805-814
-
-
Stelmanska, E.1
Korczynska, J.2
Swierczynski, J.3
-
65
-
-
21244490885
-
Effects of diet and exercise on muscle and liver intracellular lipid contents and insulin sensitivity in type 2 diabetic patients
-
Tamura Y, Tanaka Y, Sato F, Choi JB, Watada H, Niwa M, Kinoshita J, Ooka A, Kumashiro N, Igarashi Y, Kyogoku S, Maehara T, Kawasumi M, Hirose T, and Kawamori R. Effects of diet and exercise on muscle and liver intracellular lipid contents and insulin sensitivity in type 2 diabetic patients. J Clin Endocrinol Metab 90: 3191-3196, 2005.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 3191-3196
-
-
Tamura, Y.1
Tanaka, Y.2
Sato, F.3
Choi, J.B.4
Watada, H.5
Niwa, M.6
Kinoshita, J.7
Ooka, A.8
Kumashiro, N.9
Igarashi, Y.10
Kyogoku, S.11
Maehara, T.12
Kawasumi, M.13
Hirose, T.14
Kawamori, R.15
-
66
-
-
0038697895
-
Intramyocellular lipids: Anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity
-
Thamer C, Machann J, Bachmann O, Haap M, Dahl D, Wietek B, Tschritter O, Niess A, Brechtel K, Fritsche A, Claussen C, Jacob S, Schick F, Haring HU, and Stumvoll M. Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity. J Clin Endocrinol Metab 88: 1785-1791, 2003.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 1785-1791
-
-
Thamer, C.1
Machann, J.2
Bachmann, O.3
Haap, M.4
Dahl, D.5
Wietek, B.6
Tschritter, O.7
Niess, A.8
Brechtel, K.9
Fritsche, A.10
Claussen, C.11
Jacob, S.12
Schick, F.13
Haring, H.U.14
Stumvoll, M.15
-
67
-
-
21244444320
-
The "obese insulin-sensitive" adolescent: Importance of adiponectin and lipid partitioning
-
Weiss R, Taksali SE, Dufour S, Yeckel CW, Papademetris X, Cline G, Tamborlane WV, Dziura J, Shulman GI, and Caprio S. The "obese insulin-sensitive" adolescent: importance of adiponectin and lipid partitioning. J Clin Endocrinol Metab 90: 3731-3737, 2005.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 3731-3737
-
-
Weiss, R.1
Taksali, S.E.2
Dufour, S.3
Yeckel, C.W.4
Papademetris, X.5
Cline, G.6
Tamborlane, W.V.7
Dziura, J.8
Shulman, G.I.9
Caprio, S.10
-
68
-
-
3543054528
-
Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle
-
Widegren U, Jiang XJ, Krook A, Chibalin AV, Bjornholm M, Tally M, Roth RA, Henriksson J, Wallberg-henriksson H, and Zierath JR. Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle. FASEB J 12: 1379-1389, 1998.
-
(1998)
FASEB J
, vol.12
, pp. 1379-1389
-
-
Widegren, U.1
Jiang, X.J.2
Krook, A.3
Chibalin, A.V.4
Bjornholm, M.5
Tally, M.6
Roth, R.A.7
Henriksson, J.8
Wallberg-henriksson, H.9
Zierath, J.R.10
-
69
-
-
0035880844
-
Effects of concentric and eccentric contractions on phosphorylation of MAPK(ERK1/2) and MAPK(p38) in isolated rat skeletal muscle
-
Wretman C, Lionikas A, Widegren U, Lannergren J, Westerblad H, and Henriksson J. Effects of concentric and eccentric contractions on phosphorylation of MAPK(ERK1/2) and MAPK(p38) in isolated rat skeletal muscle. J Physiol 535: 155-164, 2001.
-
(2001)
J Physiol
, vol.535
, pp. 155-164
-
-
Wretman, C.1
Lionikas, A.2
Widegren, U.3
Lannergren, J.4
Westerblad, H.5
Henriksson, J.6
-
70
-
-
0033799592
-
Differential activation of mitogen-activated protein kinase signalling pathways by isometric contractions in isolated slow- and fast-twitch rat skeletal muscle
-
Wretman C, Widegren U, Lionikas A, Westerblad H, and Henriksson J. Differential activation of mitogen-activated protein kinase signalling pathways by isometric contractions in isolated slow- and fast-twitch rat skeletal muscle. Acta Physiol Scand 170: 45-49, 2000.
-
(2000)
Acta Physiol Scand
, vol.170
, pp. 45-49
-
-
Wretman, C.1
Widegren, U.2
Lionikas, A.3
Westerblad, H.4
Henriksson, J.5
-
71
-
-
4143075930
-
Direct demonstration of lipid sequestration as a mechanism by which rosiglitazone prevents fatty-acid-induced insulin resistance in the rat: Comparison with metformin
-
Ye JM, Dzamko N, Cleasby ME, Hegarty BD, Furler SM, Cooney GJ, and Kraegen EW. Direct demonstration of lipid sequestration as a mechanism by which rosiglitazone prevents fatty-acid-induced insulin resistance in the rat: comparison with metformin. Diabetologia 47: 1306-1313, 2004.
-
(2004)
Diabetologia
, vol.47
, pp. 1306-1313
-
-
Ye, J.M.1
Dzamko, N.2
Cleasby, M.E.3
Hegarty, B.D.4
Furler, S.M.5
Cooney, G.J.6
Kraegen, E.W.7
-
72
-
-
0037184925
-
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
-
Yu C, Chen Y, Cline GW, Zhang D, Zong H, Wang Y, Bergeron R, Kim JK, Cushman SW, Cooney GJ, Atcheson B, White MF, Kraegen EW, and Shulman GI. Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem 277: 50230-50236, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 50230-50236
-
-
Yu, C.1
Chen, Y.2
Cline, G.W.3
Zhang, D.4
Zong, H.5
Wang, Y.6
Bergeron, R.7
Kim, J.K.8
Cushman, S.W.9
Cooney, G.J.10
Atcheson, B.11
White, M.F.12
Kraegen, E.W.13
Shulman, G.I.14
-
73
-
-
0035477471
-
Marathon running increases ERK1/2 and p38 MAP kinase signalling to downstream targets in human skeletal muscle
-
Yu M, Blomstrand E, Chibalin AV, Krook A, and Zierath JR. Marathon running increases ERK1/2 and p38 MAP kinase signalling to downstream targets in human skeletal muscle. J Physiol 536: 273-282, 2001.
-
(2001)
J Physiol
, vol.536
, pp. 273-282
-
-
Yu, M.1
Blomstrand, E.2
Chibalin, A.V.3
Krook, A.4
Zierath, J.R.5
-
74
-
-
12244267094
-
Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise
-
Yu M, Stepto NK, Chibalin AV, Fryer LG, Carling D, Krook A, Hawley JA, and Zierath JR. Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise. J Physiol 546: 327-335, 2003.
-
(2003)
J Physiol
, vol.546
, pp. 327-335
-
-
Yu, M.1
Stepto, N.K.2
Chibalin, A.V.3
Fryer, L.G.4
Carling, D.5
Krook, A.6
Hawley, J.A.7
Zierath, J.R.8
|