-
1
-
-
0016791569
-
Insulin receptor deficiency in genetic and acquired obesity
-
Soll, A.H., C.R. Kahn, D.M. Neville, Jr., and J. Roth. 1975. Insulin receptor deficiency in genetic and acquired obesity. J. Clin. Invest. 56:769-780.
-
(1975)
J. Clin. Invest.
, vol.56
, pp. 769-780
-
-
Soll, A.H.1
Kahn, C.R.2
Neville Jr., D.M.3
Roth, J.4
-
2
-
-
0027190677
-
Defect in skeletal muscle phosphatidylinositol-3-kinase in obese insulin-resistant mice
-
Heydrick, S.J., D. Jullien, N. Gautier, J.F. Tanti, S. Giorgetti, E. Van Obberghen, and Y. Le Marchand-Brustel. 1993. Defect in skeletal muscle phosphatidylinositol-3-kinase in obese insulin-resistant mice. J. Clin. Invest. 91: 1358-1366.
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 1358-1366
-
-
Heydrick, S.J.1
Jullien, D.2
Gautier, N.3
Tanti, J.F.4
Giorgetti, S.5
Van Obberghen, E.6
Le Marchand-Brustel, Y.7
-
3
-
-
0030028959
-
Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor
-
Chua, S.C., Jr., W.K. Chung, X.S. Wu-Peng, Y. Zhang, S.M. Liu, L.A. Tartaglia, and R.L. Leibel. 1996. Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science. 271:994-996.
-
(1996)
Science
, vol.271
, pp. 994-996
-
-
Chua Jr., S.C.1
Chung, W.K.2
Wu-Peng, X.S.3
Zhang, Y.4
Liu, S.M.5
Tartaglia, L.A.6
Leibel, R.L.7
-
4
-
-
0026459873
-
Insulin resistance in obese Zucker rat (fa/fa) skeletal muscle is associated with a failure of glucose transporter translocation
-
King, P.A., E.D. Horton, M.F. Hirschman, and E.S. Horton. 1992. Insulin resistance in obese Zucker rat (fa/fa) skeletal muscle is associated with a failure of glucose transporter translocation. J. Clin. Invest. 90:1568-1575.
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 1568-1575
-
-
King, P.A.1
Horton, E.D.2
Hirschman, M.F.3
Horton, E.S.4
-
5
-
-
0015918902
-
Insulin receptor interaction in the obese hyperglycemic mouse. A model of insulin resistance
-
Kahn, C.R., D.M. Neville, Jr., and J. Roth. 1973. Insulin receptor interaction in the obese hyperglycemic mouse. A model of insulin resistance. J. Biol. Chem. 248:244-250.
-
(1973)
J. Biol. Chem.
, vol.248
, pp. 244-250
-
-
Kahn, C.R.1
Neville Jr., D.M.2
Roth, J.3
-
6
-
-
0027484001
-
Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus
-
Folli, F., M.J.A. Saad, J.M. Backer, and C.R. Kahn. 1993. Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus. J. Clin. Invest. 92:1787-1794.
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 1787-1794
-
-
Folli, F.1
Saad, M.J.A.2
Backer, J.M.3
Kahn, C.R.4
-
7
-
-
0028904053
-
Insulin action and the insulin signaling network
-
Cheatham, B., and C.R. Kahn. 1995. Insulin action and the insulin signaling network. Endocr. Rev. 16:117-142.
-
(1995)
Endocr. Rev.
, vol.16
, pp. 117-142
-
-
Cheatham, B.1
Kahn, C.R.2
-
8
-
-
0029135003
-
New frontiers in insulin receptor substrate signaling
-
Myers, M.G., Jr., and M.F. White. 1995. New frontiers in insulin receptor substrate signaling. Trends Endocrinol. Metab. 6:209-215.
-
(1995)
Trends Endocrinol. Metab.
, vol.6
, pp. 209-215
-
-
Myers Jr., M.G.1
White, M.F.2
-
9
-
-
0025813375
-
The structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
-
Sun, X.J., P.L. Rothenberg, C.R. Kahn, J.M. Backer, E. Araki, P.A. Wilden, D.A. Cahill, B.J. Goldstein, and M.F. White. 1991. The structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. Nature. 352:73-77.
-
(1991)
Nature
, vol.352
, pp. 73-77
-
-
Sun, X.J.1
Rothenberg, P.L.2
Kahn, C.R.3
Backer, J.M.4
Araki, E.5
Wilden, P.A.6
Cahill, D.A.7
Goldstein, B.J.8
White, M.F.9
-
10
-
-
0029148591
-
Role of IRS-2 in insulin and cytokine signaling
-
Sun, X.J., L.M. Wang, Y. Zhang, L. Yenush, M.G. Myers, Jr., E.M. Glasheen, W.S. Lane, J.H. Pierce, and M.F. White. 1995. Role of IRS-2 in insulin and cytokine signaling. Nature. 377:173-177.
-
(1995)
Nature
, vol.377
, pp. 173-177
-
-
Sun, X.J.1
Wang, L.M.2
Zhang, Y.3
Yenush, L.4
Myers Jr., M.G.5
Glasheen, E.M.6
Lane, W.S.7
Pierce, J.H.8
White, M.F.9
-
11
-
-
0028032895
-
Alternative pathway of insulin signaling in mice with targeted disruption of the IRS-1 gene
-
Araki, E., M.A. Lipes, M.E. Patti, J.C. Bruning, B.L. Haag, III, R.S. Johnson, and C.R. Kahn. 1994. Alternative pathway of insulin signaling in mice with targeted disruption of the IRS-1 gene. Nature. 372:186-190.
-
(1994)
Nature
, vol.372
, pp. 186-190
-
-
Araki, E.1
Lipes, M.A.2
Patti, M.E.3
Bruning, J.C.4
Haag III, B.L.5
Johnson, R.S.6
Kahn, C.R.7
-
12
-
-
0028032894
-
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1
-
Tamemoto, H., T. Kadowaki, K. Tobe, T. Yagi, H. Sakura, T. Hayakawa, Y. Terauchi, K. Ueki, Y. Kaburagi, S. Satoh, et al. 1994. Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. Nature. 372:182-186.
-
(1994)
Nature
, vol.372
, pp. 182-186
-
-
Tamemoto, H.1
Kadowaki, T.2
Tobe, K.3
Yagi, T.4
Sakura, H.5
Hayakawa, T.6
Terauchi, Y.7
Ueki, K.8
Kaburagi, Y.9
Satoh, S.10
-
13
-
-
0028810236
-
4PS/IRS-2 is the alternative substrate of the insulin receptor in IRS-I deficient mice
-
Patti, M.E., X.J. Sun, J.C. Bruning, E. Araki, M.A. Lipes, M.F. White, and C.R. Kahn. 1995. 4PS/IRS-2 is the alternative substrate of the insulin receptor in IRS-I deficient mice. J. Biol. Chem. 270:24670-24673.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 24670-24673
-
-
Patti, M.E.1
Sun, X.J.2
Bruning, J.C.3
Araki, E.4
Lipes, M.A.5
White, M.F.6
Kahn, C.R.7
-
14
-
-
0028308412
-
Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase DNA synthesis and glucose transporter translocation
-
Cheatham, B., C.J. Vlahos, L. Cheatham, L. Wang, J. Blenis, and C.R. Kahn. 1994. Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase DNA synthesis and glucose transporter translocation. Mol. Cell. Biol. 14:4902-4911.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 4902-4911
-
-
Cheatham, B.1
Vlahos, C.J.2
Cheatham, L.3
Wang, L.4
Blenis, J.5
Kahn, C.R.6
-
15
-
-
0025064397
-
Phosphatidylinositol kinase or an associated protein is a substrate for the insulin receptor tyrosine kinase
-
Endemann, G., K. Yonezawa, and R.A. Roth. 1990. Phosphatidylinositol kinase or an associated protein is a substrate for the insulin receptor tyrosine kinase. J. Biol. Chem. 265:396-400.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 396-400
-
-
Endemann, G.1
Yonezawa, K.2
Roth, R.A.3
-
16
-
-
0027437376
-
Pleiotropic insulin signals are engaged by multisite phosphoryla-tion of IRS-1
-
Sun, X.J., D.L. Crimmins, M.G. Myers, Jr., M. Miralpeix, and M.F. White. 1993. Pleiotropic insulin signals are engaged by multisite phosphoryla-tion of IRS-1. Mol. Cell. Biol. 13:7418-7428.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7418-7428
-
-
Sun, X.J.1
Crimmins, D.L.2
Myers Jr., M.G.3
Miralpeix, M.4
White, M.F.5
-
17
-
-
0026668877
-
Insulin and insulinomimetic agents induce activation of phosphatidylinositol 3′-kinase upon its association with pp185 (IRS-1) in intact rat livers
-
Hadari, Y.R., E. Tzahar, O. Nadiv, P. Rothenberg, C.T. Roberts, Jr., D. LeRoith, Y. Yarden, and Y. Zick. 1992. Insulin and insulinomimetic agents induce activation of phosphatidylinositol 3′-kinase upon its association with pp185 (IRS-1) in intact rat livers. J. Biol. Chem. 267:17483-17486.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17483-17486
-
-
Hadari, Y.R.1
Tzahar, E.2
Nadiv, O.3
Rothenberg, P.4
Roberts Jr., C.T.5
Leroith, D.6
Yarden, Y.7
Zick, Y.8
-
18
-
-
0026660653
-
Phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation
-
Backer, J.M., M.G. Myers, Jr., S.E. Shoelson, D.J. Chin, X.J. Sun, M. Miralpeix, P. Hu, B. Margolis, E.Y. Skolnik, J. Schlessinger, and M.F. White. 1992. Phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation. EMBO (Enr. Mol. Biol. Organ.) J. 11:3469-3479.
-
(1992)
EMBO (Enr. Mol. Biol. Organ.) J.
, vol.11
, pp. 3469-3479
-
-
Backer, J.M.1
Myers Jr., M.G.2
Shoelson, S.E.3
Chin, D.J.4
Sun, X.J.5
Miralpeix, M.6
Hu, P.7
Margolis, B.8
Skolnik, E.Y.9
Schlessinger, J.10
White, M.F.11
-
19
-
-
0026720350
-
Phosphatidylinositol 3-kinase: Structure and expression of the 110 kD catalytic subunit
-
Hiles, I.D., M. Otsu, S. Volinna, M.J. Fry, I. Gout, R. Dhand, G. Panayotou, F. Ruiz-Larrea, A. Thompson, N.F. Totty, et al. 1992. Phosphatidylinositol 3-kinase: structure and expression of the 110 kD catalytic subunit. Cell. 70: 419-429.
-
(1992)
Cell
, vol.70
, pp. 419-429
-
-
Hiles, I.D.1
Otsu, M.2
Volinna, S.3
Fry, M.J.4
Gout, I.5
Dhand, R.6
Panayotou, G.7
Ruiz-Larrea, F.8
Thompson, A.9
Totty, N.F.10
-
20
-
-
0025727594
-
cDNA cloning of a novel 85 kD protein that has SH2 domains and regulates binding of P13-kinase to the PDGF β-receptor
-
Escobedo, J.A., S. Navankasattusas, W.M. Kavanaugh, D. Milfay, V.A. Fried, and L.T. Williams. 1991. cDNA cloning of a novel 85 kD protein that has SH2 domains and regulates binding of P13-kinase to the PDGF β-receptor. Cell. 65:75-82.
-
(1991)
Cell
, vol.65
, pp. 75-82
-
-
Escobedo, J.A.1
Navankasattusas, S.2
Kavanaugh, W.M.3
Milfay, D.4
Fried, V.A.5
Williams, L.T.6
-
21
-
-
0025755422
-
c-src complexes and PI3-kinase
-
c-src complexes and PI3-kinase. Cell. 65:91-104.
-
(1991)
Cell
, vol.65
, pp. 91-104
-
-
Otsu, M.1
Hiles, I.2
Gout, I.3
Fry, M.J.4
Ruis-Larrea, F.5
Panayotou, G.6
Thompson, A.7
Dhand, R.8
Hsuan, J.J.9
Totty, N.F.10
-
22
-
-
0025921611
-
Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases
-
Skolnik, E.Y., B. Margolis, M. Mohammadi, E.J. Lowenstein, R. Fischer, A. Drepps, A. Ullrich, and J. Schlessinger. 1991. Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases. Cell. 65:83-90.
-
(1991)
Cell
, vol.65
, pp. 83-90
-
-
Skolnik, E.Y.1
Margolis, B.2
Mohammadi, M.3
Lowenstein, E.J.4
Fischer, R.5
Drepps, A.6
Ullrich, A.7
Schlessinger, J.8
-
23
-
-
0028486018
-
Phosphatidylinositol 3-kinase
-
Kapeller, R., and L.C. Cantley, Jr. 1994. Phosphatidylinositol 3-kinase. BioEssays. 16:565-576.
-
(1994)
BioEssays
, vol.16
, pp. 565-576
-
-
Kapeller, R.1
Cantley Jr., L.C.2
-
24
-
-
0029913340
-
Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain
-
Antonetti, D.A., P. Algenstaedt, and C.R. Kahn. 1996. Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain. Mol. Cell. Biol. 16:2195-2203.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2195-2203
-
-
Antonetti, D.A.1
Algenstaedt, P.2
Kahn, C.R.3
-
25
-
-
0029920935
-
PIK is generated by alternative splicing of the p85α gene
-
PIK is generated by alternative splicing of the p85α gene. J. Biol. Chem. 271: 5317-5320.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5317-5320
-
-
Inukai, K.1
Anai, M.2
Van Breda, E.3
Hosaka, T.4
Katagiri, H.5
Funaki, M.6
Fukushima, Y.7
Ogihara, T.8
Yazaki, Y.9
Kikuchi, M.10
-
26
-
-
0030615068
-
p85α gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-kinase), p50α, p55α, and p85α, with different PI 3-kinase activity elevating responses to insulin
-
Inukai, K., M. Funaki, T. Ogihara, H. Katagiri, A. Kanda, M. Anai, Y. Fukushima, T. Hosaka, M. Suzuki, B.C. Shin, et al. 1997. p85α gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-kinase), p50α, p55α, and p85α, with different PI 3-kinase activity elevating responses to insulin. J. Biol. Chem. 272:7873-7882.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7873-7882
-
-
Inukai, K.1
Funaki, M.2
Ogihara, T.3
Katagiri, H.4
Kanda, A.5
Anai, M.6
Fukushima, Y.7
Hosaka, T.8
Suzuki, M.9
Shin, B.C.10
-
27
-
-
0030271565
-
Structural organization and alternative splicing of the murine phosphoinositide 3-kinase p85α gene
-
Fruman, D.A., L.C. Cantley, and C.L. Carpenter. 1996. Structural organization and alternative splicing of the murine phosphoinositide 3-kinase p85α gene. Genomics. 37:113-121.
-
(1996)
Genomics
, vol.37
, pp. 113-121
-
-
Fruman, D.A.1
Cantley, L.C.2
Carpenter, C.L.3
-
28
-
-
0028982198
-
PIK reveals a new regulatory subunit for the phosphatidylinositol-3 kinase. Mol
-
PIK reveals a new regulatory subunit for the phosphatidylinositol-3 kinase. Mol. Cell. Biol. 15:4453-4465.
-
(1995)
Cell. Biol.
, vol.15
, pp. 4453-4465
-
-
Pons, S.1
Asano, T.2
Glasheen, E.M.3
Miralpeix, M.4
Zhang, Y.5
Fisher, T.L.6
Myers Jr., M.G.7
Sun, X.J.8
White, M.F.9
-
29
-
-
0038155702
-
Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IKS-1 null alleles
-
Bruning, J.C., J. Winnay, S. Bonner-Weir, S.I. Taylor, D. Accili, and C.R. Kahn. 1997. Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IKS-1 null alleles. Cell. 88:561-572.
-
(1997)
Cell
, vol.88
, pp. 561-572
-
-
Bruning, J.C.1
Winnay, J.2
Bonner-Weir, S.3
Taylor, S.I.4
Accili, D.5
Kahn, C.R.6
-
30
-
-
0028198330
-
The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity
-
Klippel, A., J.A. Escobedo, M. Hirano, and L.T. Williams. 1994. The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity. Mol. Cell. Biol. 14:2675-2685.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2675-2685
-
-
Klippel, A.1
Escobedo, J.A.2
Hirano, M.3
Williams, L.T.4
-
31
-
-
0030028790
-
A Grb2-associated docking protein in EGF- and insulin-receptor signaling
-
Holgado-Madruga, M., D.R. Emlet, D.K. Moscatello, A.K. Godwin, and A.J. Wong. 1996. A Grb2-associated docking protein in EGF- and insulin-receptor signaling. Nature. 379:560-563.
-
(1996)
Nature
, vol.379
, pp. 560-563
-
-
Holgado-Madruga, M.1
Emlet, D.R.2
Moscatello, D.K.3
Godwin, A.K.4
Wong, A.J.5
-
32
-
-
0027417484
-
The insulin-elicited 60-kD phosphotyrosine protein in rat adipocytes is associated with phosphatidylinositol 3-kinase
-
Lavan, B.E., and G.E. Lienhard. 1993. The insulin-elicited 60-kD phosphotyrosine protein in rat adipocytes is associated with phosphatidylinositol 3-kinase. J. Biol. Chem. 268:5921-5928.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 5921-5928
-
-
Lavan, B.E.1
Lienhard, G.E.2
-
33
-
-
0030757915
-
IRS3) in adipose cells
-
IRS3) in adipose cells. Biochemistry. 36:8304-8310.
-
(1997)
Biochemistry
, vol.36
, pp. 8304-8310
-
-
Smith-Hall, J.1
Pons, S.2
Patti, M.E.3
Burks, D.J.4
Yenush, L.5
Sun, X.J.6
Kahn, C.R.7
White, M.F.8
-
34
-
-
0027288587
-
The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS-1 and Shc: Implications for insulin control of ras signaling
-
Skolnik, E.Y., C.H. Lee, A.G. Batzer, L.M. Vicentini, M. Zhou, R.J. Daly, M.G. Myers, Jr., J.M. Backer, A. Ullrich, M.F. White, and J. Schlessinger. 1993. The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS-1 and Shc: implications for insulin control of ras signaling. EMBO (Eur. Mol. Biol. Organ.) J. 12:1929-1936.
-
(1993)
EMBO (Eur. Mol. Biol. Organ.) J.
, vol.12
, pp. 1929-1936
-
-
Skolnik, E.Y.1
Lee, C.H.2
Batzer, A.G.3
Vicentini, L.M.4
Zhou, M.5
Daly, R.J.6
Myers Jr., M.G.7
Backer, J.M.8
Ullrich, A.9
White, M.F.10
Schlessinger, J.11
-
35
-
-
0026471539
-
Identification of a human src homology 2-containing protein-tyrosine-phosphatase: A putative homolog of Drosophila corkscrew
-
Freeman, R.M., Jr., J. Plutzky, and B.G. Neel. 1992. Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew. Proc. Natl. Acad. Sci. USA. 89:11239-11243.
-
(1992)
Proc. Natl. Acad. Sci. USA.
, vol.89
, pp. 11239-11243
-
-
Freeman Jr., R.M.1
Plutzky, J.2
Neel, B.G.3
-
36
-
-
0027516706
-
IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3′-kinase
-
Myers, M.G., Jr., X.J. Sun, B. Cheatham, B.R. Jachna, E.M. Glasheen, J.M. Backer, and M.F. White. 1993. IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3′-kinase. Endocrinology. 132:1421-1430.
-
(1993)
Endocrinology
, vol.132
, pp. 1421-1430
-
-
Myers Jr., M.G.1
Sun, X.J.2
Cheatham, B.3
Jachna, B.R.4
Glasheen, E.M.5
Backer, J.M.6
White, M.F.7
-
37
-
-
0027500821
-
Expression, purification and characterization of SH2-containing protein tyrosine phosphatase, SH-PTP2
-
Sugimoto, S., R.J. Lechleider, S.E. Shoelson, B.G. Neel, and C.T. Walsh. 1994. Expression, purification and characterization of SH2-containing protein tyrosine phosphatase, SH-PTP2. J. Biol. Chem. 268:22771-22776.
-
(1994)
J. Biol. Chem.
, vol.268
, pp. 22771-22776
-
-
Sugimoto, S.1
Lechleider, R.J.2
Shoelson, S.E.3
Neel, B.G.4
Walsh, C.T.5
-
38
-
-
0026438979
-
Regulation of insulin receptor substrate 1 in liver and muscle of animal models of insulin resistance
-
Saad, M.J.A., E. Araki, M. Miralpeix, P.L. Rothenberg, M.F. White, and C.R. Kahn. 1992. Regulation of insulin receptor substrate 1 in liver and muscle of animal models of insulin resistance. J. Clin. Invest. 90:1839-1849.
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 1839-1849
-
-
Saad, M.J.A.1
Araki, E.2
Miralpeix, M.3
Rothenberg, P.L.4
White, M.F.5
Kahn, C.R.6
-
39
-
-
0027489828
-
Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats
-
Saad, M.J.A., F. Folli, J.A. Kahn, and C.R. Kahn. 1993. Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats. J. Clin. Invest. 92:2065-2072.
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 2065-2072
-
-
Saad, M.J.A.1
Folli, F.2
Kahn, J.A.3
Kahn, C.R.4
-
40
-
-
0028957037
-
Identification of a 190 kD protein as a novel substrate for the insulin receptor kinase functionally similar to insulin receptor substrate-1
-
Tobe, K., H. Tamemoto, T. Yamauchi, S. Aizawa, Y. Yazaki, and T. Kadowaki. 1995. Identification of a 190 kD protein as a novel substrate for the insulin receptor kinase functionally similar to insulin receptor substrate-1. J. Biol. Chem. 270:5698-5701.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 5698-5701
-
-
Tobe, K.1
Tamemoto, H.2
Yamauchi, T.3
Aizawa, S.4
Yazaki, Y.5
Kadowaki, T.6
-
41
-
-
0030848782
-
A novel 160 kD phosphotyrosinc protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family
-
Lavan, B.E., V.R. Fantin, E.T. Chang, W.S. Lane, S.R. Keller, and G.E. Lienhard. 1997. A novel 160 kD phosphotyrosinc protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family. J. Biol. Chem. 272:21403-21407.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21403-21407
-
-
Lavan, B.E.1
Fantin, V.R.2
Chang, E.T.3
Lane, W.S.4
Keller, S.R.5
Lienhard, G.E.6
-
42
-
-
0029080520
-
Wortmannin, a specific phosphatidylinositol 3-kinase inhibitor, inhibits adipocytic differentiation of 3T3-L1 cells
-
Tomiyama, K., H. Nakata, H. Sasa, S. Arimura, E. Nishio, and Y. Watanabe. 1995. Wortmannin, a specific phosphatidylinositol 3-kinase inhibitor, inhibits adipocytic differentiation of 3T3-L1 cells. Biochem. Biophys. Res. Commun. 212:263-269.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.212
, pp. 263-269
-
-
Tomiyama, K.1
Nakata, H.2
Sasa, H.3
Arimura, S.4
Nishio, E.5
Watanabe, Y.6
-
43
-
-
0029741689
-
Phosphatidylinositol 3-kinase inhibitors block differentiation of skeletal muscle cells
-
Kaliman, P., F. Vinals, X. Testar, M. Palacin, and A. Zorzano. 1996. Phosphatidylinositol 3-kinase inhibitors block differentiation of skeletal muscle cells. J. Biol. Chem. 271:19146-19151.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19146-19151
-
-
Kaliman, P.1
Vinals, F.2
Testar, X.3
Palacin, M.4
Zorzano, A.5
-
44
-
-
0029671058
-
Hepatocyte growth factor-induced proliferation of primary hepatocytes is mediated by activation of phosphatidylinositol 3-kinase
-
Skouteris, G.G., and E. Georgakopoulos. 1996. Hepatocyte growth factor-induced proliferation of primary hepatocytes is mediated by activation of phosphatidylinositol 3-kinase. Biochem. Biophys. Res. Commun. 218:229-233.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.218
, pp. 229-233
-
-
Skouteris, G.G.1
Georgakopoulos, E.2
-
45
-
-
0028082506
-
Regulation of human insulin receptor RNA splicing in vivo. Proc
-
Norgren, S., J. Zierath, A. Wedell, H. Wallberg-Henriksson, and H. Luthman. 1994. Regulation of human insulin receptor RNA splicing in vivo. Proc. Natl. Acad. Sci. USA. 91:1465-1469.
-
(1994)
Natl. Acad. Sci. USA.
, vol.91
, pp. 1465-1469
-
-
Norgren, S.1
Zierath, J.2
Wedell, A.3
Wallberg-Henriksson, H.4
Luthman, H.5
-
46
-
-
0027322636
-
Altered pattern of insulin receptor isotypes in skeletal muscle membranes of Type II (non-insulin-dependent) diabetic subjects
-
Kellerer, M., G. Sesti, E. Seffer, B. Obermaier-Kusser, D.E. Pongratz, L. Mosthaf, and H.U. Haring. 1993. Altered pattern of insulin receptor isotypes in skeletal muscle membranes of Type II (non-insulin-dependent) diabetic subjects. Diabetologia. 36:628-632.
-
(1993)
Diabetologia
, vol.36
, pp. 628-632
-
-
Kellerer, M.1
Sesti, G.2
Seffer, E.3
Obermaier-Kusser, B.4
Pongratz, D.E.5
Mosthaf, L.6
Haring, H.U.7
-
47
-
-
0025801714
-
Altered expression of insulin receptor types A and B in the skeletal muscle of non-insulin-dependent diabetes mellitus patients
-
Mosthaf, L., B. Vogt, H.U. Haring, and A. Ullrich. 1991. Altered expression of insulin receptor types A and B in the skeletal muscle of non-insulin-dependent diabetes mellitus patients. Proc. Natl. Acad. Sci. USA. 88:4728-4730.
-
(1991)
Proc. Natl. Acad. Sci. USA.
, vol.88
, pp. 4728-4730
-
-
Mosthaf, L.1
Vogt, B.2
Haring, H.U.3
Ullrich, A.4
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