Recognition of GPCRs by Peptide Ligands and Membrane Compartments theory: Structural Studies of Endogenous Peptide Hormones in Membrane Environment

Bioscience Reports

Volumn 26, Issue 2, 2006, Pages 131-158

  Sankararamakrishnan, Ramasubbu ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY KANPUR   (India)

Author keywords

Bicelles; GPCR activation; GPCR modeling; Induced conformation; Ligand docking; Lipid peptide interactions; Membrane protein structure; Membrane mimetic; Micelles; NMR spectroscopy; Receptor ligand interactions

Indexed keywords

CELL SURFACE PROTEIN; G PROTEIN COUPLED RECEPTOR; LIGAND; MORPHINE; OPIATE; PEPTIDE; PEPTIDE HORMONE;

AQUEOUS SOLUTION; ARTICLE; BICELLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; DRUG ACTIVITY; DRUG DESIGN; DRUG TARGETING; HORMONE STRUCTURE; LIGAND BINDING; MEMBRANE BINDING; MEMBRANE BIOLOGY; MEMBRANE COMPARTMENTS THEORY; MICELLE; MOLECULAR DYNAMICS; MOLECULAR MODEL; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN FAMILY; PROTEIN LIPID INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; THEORY; THREE DIMENSIONAL IMAGING;

LIGANDS; MICELLES; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, MOLECULAR; PEPTIDE HORMONES; PEPTIDES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, G-PROTEIN-COUPLED;

MAMMALIA;

EID: 33745506432     PISSN: 01448463     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10540-006-9014-z     Document Type: Article

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