-
1
-
-
0035098503
-
Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer
-
Risch, H. A. et al. Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. Am. J. Hum. Genet. 68, 700-710 (2001). Describes the BRCA1/BRCA2 mutation frequency and associated risks of cancer in a large, population-based series of women with invasive ovarian cancer.
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 700-710
-
-
Risch, H.A.1
-
2
-
-
0027508442
-
Pheochromocytomas, multiple endocrine neoplasia type 2, and von Hippel-Lindau disease
-
Nuemann, H. P. H. et al. Pheochromocytomas, multiple endocrine neoplasia type 2, and von Hippel-Lindau disease. N. Engl. J. Med. 329, 1531-1538 (1993).
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 1531-1538
-
-
Nuemann, H.P.H.1
-
3
-
-
10244245097
-
Relevance of RET proto-oncogene mutations in sporadic medullary thyroid carcinoma
-
Wohllk, N. et al. Relevance of RET proto-oncogene mutations in sporadic medullary thyroid carcinoma. J. Clin. Endocrinol. Metab. 81, 3740-3745 (1996).
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, pp. 3740-3745
-
-
Wohllk, N.1
-
4
-
-
0035093053
-
A genetic epidemiology study of carcinoma of the fallopian tube
-
Aziz, S. et al. A genetic epidemiology study of carcinoma of the fallopian tube. Gynecol. Oncol. 80, 341-345 (2001).
-
(2001)
Gynecol. Oncol.
, vol.80
, pp. 341-345
-
-
Aziz, S.1
-
5
-
-
0031832541
-
Sequence analysis of BRCA1 and BRCA2: Correlation of mutations with family history and ovarian cancer risk
-
Frank, T. S. et al. Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk. J. Clin. Oncol. 16, 2417-2425 (1998).
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 2417-2425
-
-
Frank, T.S.1
-
6
-
-
0030910022
-
The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews
-
Struewing, J. P. et al. The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. N. Engl. J. Med. 336, 1401-1408 (1997).
-
(1997)
N. Engl. J. Med.
, vol.336
, pp. 1401-1408
-
-
Struewing, J.P.1
-
7
-
-
16044366171
-
Frequency of recurrent BRCA1 and BRCA2 mutations in 222 Ashkenazi Jewish breast cancer families
-
Tonin, P. et al. Frequency of recurrent BRCA1 and BRCA2 mutations in 222 Ashkenazi Jewish breast cancer families. Nature Med. 2, 1179-1183 (1966).
-
(1966)
Nature Med.
, vol.2
, pp. 1179-1183
-
-
Tonin, P.1
-
8
-
-
0030956589
-
Study of a single BRCA2 mutation with high carrier frequency in a small population
-
Thorlacius, S. et al. Study of a single BRCA2 mutation with high carrier frequency in a small population. Am. J. Hum. Genet. 60, 1079-1084 (1997).
-
(1997)
Am. J. Hum. Genet.
, vol.60
, pp. 1079-1084
-
-
Thorlacius, S.1
-
9
-
-
0033939978
-
BRCA1 founder mutations in Poland
-
Gorski, B. et al. BRCA1 founder mutations in Poland. Am. J. Hum. Genet. 66, 1963-1968 (2000).
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 1963-1968
-
-
Gorski, B.1
-
10
-
-
0032191140
-
The kin-cohort study for estimating penetrance
-
Wacholder, S. et al. The kin-cohort study for estimating penetrance. Am. J. Epidemiol. 148, 623-630 (1998).
-
(1998)
Am. J. Epidemiol.
, vol.148
, pp. 623-630
-
-
Wacholder, S.1
-
11
-
-
0033591850
-
Prevalence of BRCA mutations in an unselected population of Ashkenazi Jewish women with ovarian cancer
-
Warner, E. et al. Prevalence of BRCA mutations in an unselected population of Ashkenazi Jewish women with ovarian cancer. J. Natl. Cancer Inst. 91, 1241-1247 (1999).
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 1241-1247
-
-
Warner, E.1
-
12
-
-
0033927850
-
BRCA1 and BRCA2 mutation analysis of 230 Ashkenazi Jewish women with ovarian cancer
-
Moslehi, R. et al. BRCA1 and BRCA2 mutation analysis of 230 Ashkenazi Jewish women with ovarian cancer. Am. J. Hum. Genet 55, 1259-1272 (2000).
-
(2000)
Am. J. Hum. Genet.
, vol.55
, pp. 1259-1272
-
-
Moslehi, R.1
-
13
-
-
17344365851
-
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families
-
Ford, D. et al. Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. Am. J. Hum. Genet. 62, 676-689 (1998). Uses a panel of 237 families with a high incidence of breast cancer to estimate the cumulative risks of breast and ovarian cancer in carriers of BRCA1 and BRCA2 mutations.
-
(1998)
Am. J. Hum. Genet.
, vol.62
, pp. 676-689
-
-
Ford, D.1
-
14
-
-
0028843102
-
Breast and ovarian cancer incidence in BRCA1 mutation carriers
-
Easton, D. F. et al. Breast and ovarian cancer incidence in BRCA1 mutation carriers. Am. J. Hum. Genet. 56, 265-271 (1995).
-
(1995)
Am. J. Hum. Genet.
, vol.56
, pp. 265-271
-
-
Easton, D.F.1
-
15
-
-
0035913275
-
Breast cancer after prophylactic bilateral mastectomy in women with a BRCA1 or BRCA2 mutation
-
Meijers-Heijboer, H. et al. Breast cancer after prophylactic bilateral mastectomy in women with a BRCA1 or BRCA2 mutation. N. Engl. J. Med. 345, 159-164 (2001).
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 159-164
-
-
Meijers-Heijboer, H.1
-
16
-
-
16144368180
-
A polymorphic stop codon in BRCA2
-
Mazoyer, S. et al. A polymorphic stop codon in BRCA2. Nature Genet. 14, 253-254 (1996).
-
(1996)
Nature Genet.
, vol.14
, pp. 253-254
-
-
Mazoyer, S.1
-
17
-
-
0035125062
-
Variation in cancer risks by mutation position, in BRCA2 mutation carriers
-
Thompson, D. & Easton, D. Variation in cancer risks by mutation position, in BRCA2 mutation carriers. Am. J. Hum. Genet. 66, 410-419 (2001). Uses a panel of 164 families with BRCA2 mutations to estimate the risks of breast and ovarian cancer by position of mutation in the BRCA2 gene.
-
(2001)
Am. J. Hum. Genet.
, vol.66
, pp. 410-419
-
-
Thompson, D.1
Easton, D.2
-
18
-
-
0028844202
-
Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype-phenotype correlation
-
Gayther, S. A. et al Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype-phenotype correlation. Nature Genet. 11, 428-433 (1995). Uses a panel of 60 families with BRCA1 mutations to correlate the position of the mutation within the BRCA1 gene with the ratio of breast and ovarian cancers in the family.
-
(1995)
Nature Genet.
, vol.11
, pp. 428-433
-
-
Gayther, S.A.1
-
19
-
-
0032231617
-
Frequency and carrier risk associated with common BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer patients
-
Fodor, F. L. et al. Frequency and carrier risk associated with common BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer patients. Am. J. Hum. Genet. 63, 45-51 (1998).
-
(1998)
Am. J. Hum. Genet.
, vol.63
, pp. 45-51
-
-
Fodor, F.L.1
-
20
-
-
23544433295
-
Polymorphisms in BRCA1 and 17β-hydroxysteroid dehydrogenase 2 (EDH17B2) genes as modifiers of ovarian cancer risk in carriers of BRCA1 germline mutations
-
Sinilnikova, O. et al. Polymorphisms in BRCA1 and 17β -hydroxysteroid dehydrogenase 2 (EDH17B2) genes as modifiers of ovarian cancer risk in carriers of BRCA1 germline mutations. Am. J. Hum. Genet. 69, S150 (2001).
-
(2001)
Am. J. Hum. Genet.
, vol.69
-
-
Sinilnikova, O.1
-
21
-
-
0032547341
-
Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4
-
Rebbeck, T. R., Jaffe, J. M., Walker, A. H., Wein, A. J. & Malkowicz, S. B. Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4. J. Natl Cancer Inst. 90, 1225-1229 (1998).
-
(1998)
J. Natl. Cancer Inst.
, vol.90
, pp. 1225-1229
-
-
Rebbeck, T.R.1
Jaffe, J.M.2
Walker, A.H.3
Wein, A.J.4
Malkowicz, S.B.5
-
22
-
-
0035715780
-
Genetic factors related to racial variation in plasma levels of insulin-like growth factor-1: Implications for premenopausal breast cancer risk
-
Jernstrom, H. et al. Genetic factors related to racial variation in plasma levels of insulin-like growth factor-1: implications for premenopausal breast cancer risk. Mol. Genet. Metab. 72, 144-154 (2001).
-
(2001)
Mol. Genet. Metab.
, vol.72
, pp. 144-154
-
-
Jernstrom, H.1
-
23
-
-
0028033594
-
The length and location of CAG trinucleotide repeat in the androgen receptor N-terminal domain affect transactivation activities
-
Chamberlain, N. L. et al. The length and location of CAG trinucleotide repeat in the androgen receptor N-terminal domain affect transactivation activities. Nucleic Acids Res. 2, 3181-3186 (1994).
-
(1994)
Nucleic Acids Res.
, vol.2
, pp. 3181-3186
-
-
Chamberlain, N.L.1
-
24
-
-
0035421325
-
Short polyglutamine tracts in the androgen receptor are protective against breast cancer in the general population
-
Giguere, Y. et al. Short polyglutamine tracts in the androgen receptor are protective against breast cancer in the general population. Cancer Res. 61, 5869-5874 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 5869-5874
-
-
Giguere, Y.1
-
25
-
-
0033516319
-
Androgen receptor exon 1 CAG repeat length and breastcancer in women before age 40 years
-
Spurdle, A. B. et al. Androgen receptor exon 1 CAG repeat length and breastcancer in women before age 40 years. J. Natl Cancer Inst. 91, 961-966 (1999).
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 961-966
-
-
Spurdle, A.B.1
-
26
-
-
0032697596
-
No association between androgen or vitamin D receptor gene polymorphisms and risk of breast cancer
-
Dunning, A. M. et al. No association between androgen or vitamin D receptor gene polymorphisms and risk of breast cancer. Carcinogenesis 20, 2131-2135 (1999).
-
(1999)
Carcinogenesis
, vol.20
, pp. 2131-2135
-
-
Dunning, A.M.1
-
27
-
-
0034327357
-
Breast cancer susceptibility gene 1 (BRCA1) is a coactivator of the androgen receptor
-
Park, J. J. et al. Breast cancer susceptibility gene 1 (BRCA1) is a coactivator of the androgen receptor. Cancer Res. 60, 5946-5949 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 5946-5949
-
-
Park, J.J.1
-
28
-
-
0001516492
-
Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat
-
Rebbeck, T. R. et al. Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat. Am. J. Hum. Genet. 64, 1371-1377 (1999). A case-control study of BRCA1-mutation carriers, comparing the specific alleles of the androgen-receptor polymorphism and breast cancer risk. In addition, reference 24 shows this effect in the non-carrier breast cancer population.
-
(1999)
Am. J. Hum. Genet.
, vol.64
, pp. 1371-1377
-
-
Rebbeck, T.R.1
-
29
-
-
0142206381
-
Androgen receptor CAG repeat lengths in Jewish Israeli women who are BRCA1/2 mutation carriers: Relevance to breast/ovarian cancer morbidity
-
Dagan, E. et al. Androgen receptor CAG repeat lengths in Jewish Israeli women who are BRCA1/2 mutation carriers: relevance to breast/ovarian cancer morbidity. Am. J. Hum Genet. 69, 376 (2001).
-
(2001)
Am. J. Hum Genet.
, vol.69
, pp. 376
-
-
Dagan, E.1
-
30
-
-
0035110955
-
The androgen receptor and genetic susceptiblity to ovarian cancer: Results from a case series
-
Levine, D. A. & Boyd, J. The androgen receptor and genetic susceptiblity to ovarian cancer: results from a case series. Cancer Res. 61, 908-911 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 908-911
-
-
Levine, D.A.1
Boyd, J.2
-
31
-
-
0029614887
-
Serum gonadotropins and steroid hormones and the development of ovarian cancer
-
Helztsouer, K. J. et al. Serum gonadotropins and steroid hormones and the development of ovarian cancer. J. Am. Med. Assoc. 274, 1926-1930 (1995).
-
(1995)
J. Am. Med. Assoc.
, vol.274
, pp. 1926-1930
-
-
Helztsouer, K.J.1
-
32
-
-
0034612264
-
The steroid receptor coactivator SRC (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development
-
Yoshida-Komiy, H. et al. The steroid receptor coactivator SRC (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development. Proc. Natl Acad. Sci. USA 97, 6379-6384 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6379-6384
-
-
Yoshida-Komiy, H.1
-
33
-
-
0030797902
-
AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer
-
Anzick, S. L. et al. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science 277, 965-968 (1997).
-
(1997)
Science
, vol.277
, pp. 965-968
-
-
Anzick, S.L.1
-
34
-
-
0035878970
-
Modification of BRCA1- and BRCA2-associated breast cancer risk by AIB1 genotype and reproductive history
-
Rebbeck, T. R. et al. Modification of BRCA1- and BRCA2-associated breast cancer risk by AIB1 genotype and reproductive history. Cancer Res. 61, 5420-5424 (2001). Shows that the risk of breast cancer in BRCA1-mutation carriers is modified by the NCOA3 polymorphism.
-
(2001)
Cancer Res.
, vol.61
, pp. 5420-5424
-
-
Rebbeck, T.R.1
-
35
-
-
0033790661
-
Alleles of the estrogen receptor-α gene and an estrogen receptor co-transcriptional activator gene, amplified in breast cancer-1 (AIB-1) are associated with quantitative calcaneal ultrasound
-
Patel, M. S. et al. Alleles of the estrogen receptor-α gene and an estrogen receptor co-transcriptional activator gene, amplified in breast cancer-1 (AIB-1) are associated with quantitative calcaneal ultrasound. J. Bone Mineral Res. 15, 2231-2239 (2000).
-
(2000)
J. Bone Mineral Res.
, vol.15
, pp. 2231-2239
-
-
Patel, M.S.1
-
36
-
-
0032127849
-
Role of the human RAD51 protein in homologous recombination and double-stranded break repair
-
Baumann, P. & West, S. C. Role of the human RAD51 protein in homologous recombination and double-stranded break repair. Trends Biochem. Sci. 23, 247-251 (1998).
-
(1998)
Trends Biochem. Sci.
, vol.23
, pp. 247-251
-
-
Baumann, P.1
West, S.C.2
-
37
-
-
0034852155
-
A single nuclectide polymorphism in the 5′ untranslated region of RAD51 and risk of cancer among BRCA1/2 mutation carriers
-
Wang, W. et al. A single nuclectide polymorphism in the 5′ untranslated region of RAD51 and risk of cancer among BRCA1/2 mutation carriers. Cancer Epidemiol. Biomarkers Prev. 10, 421-574 (2001).
-
(2001)
Cancer Epidemiol. Biomarkers Prev.
, vol.10
, pp. 421-574
-
-
Wang, W.1
-
38
-
-
0035853077
-
A single nuclectide polymorphisms in the RAD 51 gene modifies cancer risk in BRCA2 but not BRCA1 carriers
-
Levy-Lehad, E. et al. A single nuclectide polymorphisms in the RAD51 gene modifies cancer risk in BRCA2 but not BRCA1 carriers. Proc. Natl Acad. Sci. USA 98, 3232-3236 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3232-3236
-
-
Levy-Lehad, E.1
-
39
-
-
0027214689
-
An association between the risk of cancer and mutations in the HRAS1 minisatellite locus
-
Krontiris, T. et al. An association between the risk of cancer and mutations in the HRAS1 minisatellite locus. N. Engl. J. Med. 329, 517-523 (1993). Reviews the evidence that the VNTR polymorphism, downstream of HRAS1, modifies the risk of cancer at several sites.
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 517-523
-
-
Krontiris, T.1
-
40
-
-
13344268996
-
Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus
-
Phelan, C. M. et al. Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus. Nature Genet. 12; 309-311 (1996). This study of BRCA1-mutation carriers with and without ovarian cancer shows that rare alleles of the VNTR polymorphism, downstream of HRAS1, increases the risk of ovarian cancer.
-
(1996)
Nature Genet.
, vol.12
, pp. 309-311
-
-
Phelan, C.M.1
-
41
-
-
0027498979
-
Increasing incidence of breast cancer in family with BRCA1 mutation
-
Narod, S. A. et al. Increasing incidence of breast cancer in family with BRCA1 mutation. Lancet 341, 1101-1102 (1993).
-
(1993)
Lancet
, vol.341
, pp. 1101-1102
-
-
Narod, S.A.1
-
42
-
-
0018642114
-
Genetics of retinoblastoma
-
Vogel, F. Genetics of retinoblastoma. Hum. Genet. 52, 1-54 (1979).
-
(1979)
Hum. Genet.
, vol.52
, pp. 1-54
-
-
Vogel, F.1
-
43
-
-
17344372404
-
Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: Results of an international study
-
Neuhausen, S. L. et al. Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study. Am. J. Hum. Genet. 62, 1381-1388 (1998).
-
(1998)
Am. J. Hum. Genet.
, vol.62
, pp. 1381-1388
-
-
Neuhausen, S.L.1
-
44
-
-
0029592720
-
Risk modifiers in carriers of BRCA1 mutations
-
Narod, S. A. et al. Risk modifiers in carriers of BRCA1 mutations. Int. J. Cancer 64, 394-398 (1995).
-
(1995)
Int. J. Cancer
, vol.64
, pp. 394-398
-
-
Narod, S.A.1
-
45
-
-
0033199926
-
Reduction in breast cancer risk after bilateral prophylactic oophorectomy in BRCA1 mutation carriers
-
Rebbeck, T. R. et al. Reduction in breast cancer risk after bilateral prophylactic oophorectomy in BRCA1 mutation carriers. J. Natl Cancer Inst. 91, 1475-1479 (1999). A historical cohort study that found a significant reduction in breast cancer risk in BRCA1-mutation carriers following oophorectomy.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 1475-1479
-
-
Rebbeck, T.R.1
-
46
-
-
0002048774
-
Reduction in breast cancer risk following bilateral prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers
-
Eisen, A. et al. Reduction in breast cancer risk following bilateral prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers. Am. J. Hum. Genet. 67, 58 (2000).
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 58
-
-
Eisen, A.1
-
47
-
-
0027462302
-
Childbearing, oral contraceptive use and breast cancer
-
Beral, V. & Reeves, G. Childbearing, oral contraceptive use and breast cancer. Lancet 341, 1102 (1993).
-
(1993)
Lancet
, vol.341
, pp. 1102
-
-
Beral, V.1
Reeves, G.2
-
48
-
-
0026460191
-
Influence of age and panty on the development of the human breast
-
Russo, J. et al. Influence of age and panty on the development of the human breast. Breast Cancer Res. Treat. 23, 211-218 (1992).
-
(1992)
Breast Cancer Res. Treat.
, vol.23
, pp. 211-218
-
-
Russo, J.1
-
49
-
-
0032564181
-
Pregnancy-associated breast cancer in BRCA1 and BRCA2 germline mutation carriers
-
Johannson, O., Loman, N., Borg, A. & Olsson, H. Pregnancy-associated breast cancer in BRCA1 and BRCA2 germline mutation carriers. Lancet 352, 1359-1360 (1998).
-
(1998)
Lancet
, vol.352
, pp. 1359-1360
-
-
Johannson, O.1
Loman, N.2
Borg, A.3
Olsson, H.4
-
50
-
-
0033610723
-
Pregnancy increases the risk of early onset breast cancer in BRCA1 and BRCA2 carriers
-
Jernstrom, H. et al. Pregnancy increases the risk of early onset breast cancer in BRCA1 and BRCA2 carriers. Lancet 354, 1846-1850 (1999). A case-control study that found that pregnancy significantly increased the risk of breast cancer up to age 40 in women with BRCA1 mutations.
-
(1999)
Lancet
, vol.354
, pp. 1846-1850
-
-
Jernstrom, H.1
-
51
-
-
23544458005
-
Breast-feeding and the risk of breast cancer in BRCA1 and BRCA2 carriers
-
Jernstrom, H. et al. Breast-feeding and the risk of breast cancer in BRCA1 and BRCA2 carriers. Am. J. Hum. Genet. 69, S418 (2001).
-
(2001)
Am. J. Hum. Genet.
, vol.69
-
-
Jernstrom, H.1
-
52
-
-
0030865837
-
Does oral contraceptive use increase the risk of breast cancer in women with BRCA1/BRCA2 mutations more than in other women?
-
Ursin, G. et al. Does oral contraceptive use increase the risk of breast cancer in women with BRCA1/BRCA2 mutations more than in other women? Cancer Res. 57, 3678-3681 (1997).
-
(1997)
Cancer Res.
, vol.57
, pp. 3678-3681
-
-
Ursin, G.1
-
53
-
-
0034638446
-
Risk of breast cancer with oral contraceptive use in women with a family history of breast cancer
-
Grabick, D. M. et al. Risk of breast cancer with oral contraceptive use in women with a family history of breast cancer. J. Am. Med. Assoc. 284, 1791-1798 (2000).
-
(2000)
J. Am. Med. Assoc.
, vol.284
, pp. 1791-1798
-
-
Grabick, D.M.1
-
54
-
-
0242390079
-
Breast cancer and hormonal contraceptives: Collaborative re-analysis of individual data on 53,297 women with breast cancer and 100,239 women without breast cancer from 54 epidemiological studies
-
Collaborative Group on Hormonal Factors in Breast Cancer. Breast cancer and hormonal contraceptives: collaborative re-analysis of individual data on 53,297 women with breast cancer and 100,239 women without breast cancer from 54 epidemiological studies. Lancet 347, 1713-1727 (1996).
-
(1996)
Lancet
, vol.347
, pp. 1713-1727
-
-
-
55
-
-
0032514413
-
Oral contraceptives and the risk of hereditary ovarian cancer
-
Narod, S. A. et al. Oral contraceptives and the risk of hereditary ovarian cancer. N. Engl. J. Med. 339, 424-428 (1998). An international case-control study that showed that the use of oral contraceptives was associated with a significant decrease in the risk of ovarian cancer among BRCA1-mutation carriers.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 424-428
-
-
Narod, S.A.1
-
56
-
-
0035849283
-
Tubal ligation and risk of ovarian cancer carriers of BRCA1 or BRCA2 mutations: A case-control study
-
Narod, S. A. et al. Tubal ligation and risk of ovarian cancer carriers of BRCA1 or BRCA2 mutations: a case-control study. Lancet 357, 1467-1470 (2001). An international case-control study that showed that tubal ligation was associated with a decrease in the risk of ovarian cancer. Reference 60 is a large prospective study (of nurses) that showed that tubal ligation dramatically decreased the risk of subsequent ovarian cancer.
-
(2001)
Lancet
, vol.357
, pp. 1467-1470
-
-
Narod, S.A.1
-
57
-
-
0035818882
-
Ovarian cancer, oral contraceptives, and BRCA mutations
-
Narod, S. A., Sun, P. & Risch, H. Ovarian cancer, oral contraceptives, and BRCA mutations. N. Engl. J. Med. 345, 1706-1707 (2001).
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 1706-1707
-
-
Narod, S.A.1
Sun, P.2
Risch, H.3
-
58
-
-
0035954651
-
Panty, oral contraceptives, and the risk of ovarian cancer among carriers and non-carriers of a BRCA1 or BRCA2 mutation
-
Modan, B. et al. Panty, oral contraceptives, and the risk of ovarian cancer among carriers and non-carriers of a BRCA1 or BRCA2 mutation. N. Engl. J. Med. 345, 235-240 (2001).
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 235-240
-
-
Modan, B.1
-
59
-
-
0027422350
-
Tubal ligation, hysterectomy and the risk of ovarian cancer
-
Hankinson, S. E. et al. Tubal ligation, hysterectomy and the risk of ovarian cancer. J. Am. Med. Assoc. 270, 2813-2818 (1993).
-
(1993)
J. Am. Med. Assoc.
, vol.270
, pp. 2813-2818
-
-
Hankinson, S.E.1
-
60
-
-
0035828559
-
Tubal ligation and risk of ovarian cancer
-
Piek, J. M. J. et al. Tubal ligation and risk of ovarian cancer. Lancet 358, 844 (2001).
-
(2001)
Lancet
, vol.358
, pp. 844
-
-
Piek, J.M.J.1
-
61
-
-
0032537990
-
Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project Pi study
-
Fisher, B. et al. Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project Pi study. J. Natl Cancer Inst. 90, 1371-1388 (1998). A large randomized trial of tamoxifen use in healthy women showed that tamoxifen use reduced the incidence of new cases of breast cancer by approximately 50%.
-
(1998)
J. Natl. Cancer Inst.
, vol.90
, pp. 1371-1388
-
-
Fisher, B.1
-
62
-
-
0032537396
-
Tamoxifen for early breast cancer: An overview of the randomized trials
-
Early Breast Cancer Trialists' Collaborative Group. Tamoxifen for early breast cancer: an overview of the randomized trials. Lancet 351, 1451-1467 (1998).
-
(1998)
Lancet
, vol.351
, pp. 1451-1467
-
-
-
63
-
-
0035861037
-
Tamoxifen and breast cancer incidence among women with inherited mutations in BRCA1 and BRCA2
-
National Surgical Adjuvant Breast and Bowel Project (NSABP-P1) Breast Cancer Prevention Trial
-
King, M.-C. et al. Tamoxifen and breast cancer incidence among women with inherited mutations in BRCA1 and BRCA2. National Surgical Adjuvant Breast and Bowel Project (NSABP-P1) Breast Cancer Prevention Trial. J. Am. Med. Assoc. 286, 2251-2256 (2001). This describes tamoxifen use in the subset of 19 BRCA1- or BRCA2-mutation carriers in the cohort study in reference 61 who developed breast cancer.
-
(2001)
J. Am. Med. Assoc.
, vol.286
, pp. 2251-2256
-
-
King, M.-C.1
-
64
-
-
0034597916
-
Tamoxifen and risk of contralateral breast cancer in BRCA1 and BRCA2 carriers
-
Narod, S. A. et al. Tamoxifen and risk of contralateral breast cancer in BRCA1 and BRCA2 carriers. Lancet 356, 1876-1881 (2000). A large, international case-control study, which shows that tamoxifen use decreases the risk of contralateral breast cancer by approximately 50% in carriers of BRCA1 or BRCA2 mutations.
-
(2000)
Lancet
, vol.356
, pp. 1876-1881
-
-
Narod, S.A.1
-
65
-
-
0025726582
-
A meta-analysis of the effect of estrogen replacement therapy on the risk of breast cancer
-
Steinberg, K. et al. A meta-analysis of the effect of estrogen replacement therapy on the risk of breast cancer. J. Am. Med. Assoc. 265, 1985-1990 (1991).
-
(1991)
J. Am. Med. Assoc.
, vol.265
, pp. 1985-1990
-
-
Steinberg, K.1
-
66
-
-
0032508294
-
Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial
-
Powles, T. et al. Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial. Lancet 352, 98-101 (1998).
-
(1998)
Lancet
, vol.352
, pp. 98-101
-
-
Powles, T.1
-
67
-
-
0032508293
-
Prevention of breast cancer with tamoxifen: Preliminary findings from the Italian randomised trial among hysterectomised women
-
Veronesi, U. et al. Prevention of breast cancer with tamoxifen: preliminary findings from the Italian randomised trial among hysterectomised women. Lancet 352, 93-97 (1998).
-
(1998)
Lancet
, vol.352
, pp. 93-97
-
-
Veronesi, U.1
-
68
-
-
0033523268
-
Cancer risks in BRCA2 mutation carriers
-
The Breast Cancer Linkage Consortium. Cancer risks in BRCA2 mutation carriers. J. Natl Cancer Inst. 91, 1310-1316 (1999).
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 1310-1316
-
-
-
69
-
-
0033591295
-
BRCA1 inhibition of estrogen receptor signalling in transfected cells
-
Fan, S. et al. BRCA1 inhibition of estrogen receptor signalling in transfected cells. Science 284, 1354-1356 (1999).
-
(1999)
Science
, vol.284
, pp. 1354-1356
-
-
Fan, S.1
-
70
-
-
0035859823
-
BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor
-
Zheng, L. et al. BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor. Proc. Natl Acad. Sci. USA 98, 9587-9592 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9587-9592
-
-
Zheng, L.1
-
71
-
-
0034469046
-
Increased survival by inhibition of BRCA1 using an antisense approach in an estrogen responsive ovarian carcinoma cell line
-
Annab, L. A. et al. Increased survival by inhibition of BRCA1 using an antisense approach in an estrogen responsive ovarian carcinoma cell line. Breast Cancer Res. 2, 139-148 (2000).
-
(2000)
Breast Cancer Res.
, vol.2
, pp. 139-148
-
-
Annab, L.A.1
-
72
-
-
0035902108
-
Genomic maintenance mechanisms for preventing cancer
-
Hoeijmakers, J. H. Genomic maintenance mechanisms for preventing cancer. Nature 441, 366-367 (2001).
-
(2001)
Nature
, vol.441
, pp. 366-367
-
-
Hoeijmakers, J.H.1
-
73
-
-
0034856461
-
BRCA2 and homologous recombination
-
Orelli, B. J. & Bishop, D. K. BRCA2 and homologous recombination. Breast Cancer Res. 3, 294-298 (2001).
-
(2001)
Breast Cancer Res.
, vol.3
, pp. 294-298
-
-
Orelli, B.J.1
Bishop, D.K.2
-
74
-
-
0345310068
-
Chemopreventive agents: Selenium
-
Combs, G. F. & Gray, W. P. Chemopreventive agents: selenium. Pharmacol. Ther. 79, 179-192 (1998).
-
(1998)
Pharmacol. Ther.
, vol.79
, pp. 179-192
-
-
Combs, G.F.1
Gray, W.P.2
-
75
-
-
0034904091
-
Green tea extracts decrease carcinogen-induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture
-
Kavanagh, K. T. et al. Green tea extracts decrease carcinogen-induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture. J. Cell. Biochem. 82, 387-398 (2001).
-
(2001)
J. Cell. Biochem.
, vol.82
, pp. 387-398
-
-
Kavanagh, K.T.1
-
76
-
-
0034494832
-
Preventive effects of drinking green tea on cancer and cardiovascular disease: Epidemiological evidence for multiple targeting prevention
-
Nakachi, K. et al. Preventive effects of drinking green tea on cancer and cardiovascular disease: epidemiological evidence for multiple targeting prevention. Biofactors 13, 49-54 (2000).
-
(2000)
Biofactors
, vol.13
, pp. 49-54
-
-
Nakachi, K.1
-
77
-
-
0033427186
-
Multifunctional aspects of the action of indole-3-carbinol as an antitumour agent. Cancer Prevention: Novel nutrient and pharmaceutical developments
-
Bradlow, H. L. et al. Multifunctional aspects of the action of indole-3-carbinol as an antitumour agent. Cancer Prevention: novel nutrient and pharmaceutical developments. Ann. NY Acad. Sci. 889, 204-213 (1999).
-
(1999)
Ann. NY Acad. Sci.
, vol.889
, pp. 204-213
-
-
Bradlow, H.L.1
|