Identification of a signal-responsive nuclear export sequence in class II histone deacetylases

Molecular and Cellular Biology

Volumn 21, Issue 18, 2001, Pages 6312-6321

  McKinsey, Timothy A ^a   Chun, Li Zhang ^a   Olson, Eric N ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE; MYOCYTE ENHANCER FACTOR 2; PROTEIN KINASE (CALCIUM,CALMODULIN);

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMATIN STRUCTURE; ENZYME ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REGULATORY MECHANISM;

AMINO ACID SEQUENCE; ANIMALS; COS CELLS; DNA-BINDING PROTEINS; HISTONE DEACETYLASES; MOLECULAR SEQUENCE DATA; MYOGENIC REGULATORY FACTORS; REPRESSOR PROTEINS; SEQUENCE DELETION; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS;

ANIMALIA; NES;

EID: 0035724044     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.18.6312-6321.2001     Document Type: Article

References (40)

1. Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins
2. Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear export signal delineated by a novel in vivo randomization-selection assay
3. A dynamic role for HDAC7 in MEF2-mediated muscle differentiation
4. A new family of human histone deacetylases related to Saccharomyces cerevisiae HDA1p
5. Transport between the cell nucleus and the cytoplasm
6. Three proteins define a class of human histone deacetylases related to yeast Hda1p
7. Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization
8. Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin-dependent protein kinase I kinase
9. 2+/calmodulin-dependent protein kinase type IV/Gr-deficient mice
10. Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway
11. Protein kinase C and calmodulin kinase are required for endothelin-stimulated atrial natriuretic factor secretion from primary atrial myocytes
12. Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression
13. 2+/calmodulin-dependent protein kinase in failing and nonfailing human hearts
14. MEF2 is upregulated during cardiac hypertrophy and is required for normal post-natal growth of the myocardium
15. mHDA1/HDAC5 histone deacetylase interacts with and represses MEF2A transcriptional activity
16. Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases
17. Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases
18. Neuronal activity-dependent cell survival mediated by transcription factor MEF2
19. Control of memory formation through regulated expression of a CaMKII transgene
20. Nuclear export signal located within the DNA-binding domain of the STAT1 transcription factor
21. Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation
22. Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5
23. Control of muscle development by dueling HATs and HDACs
24. HDAC4 deacetylase associates with and represses the MEF2 transcription factor
25. Antiapoptotic role of the p38 mitogen-activated protein kinase-myocyte enhancer factor 2 transcription factor pathway during neuronal differentiation
26. CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo
27. CaMKII regulates the density of central glutamatergic synapses in vivo
28. Molecular mechanisms of myogenic coactivation by p300: Direct interaction with the activation domain of MyoD and with the MADS box of MEF2C
29. MEF-2 function is modified by a novel co-repressor, MITR
30. The language of covalent histone modifications
31. Identification of a new family of higher eukaryotic histone deacetylases. Coordinate expression of differentiation-dependent chromatin modifiers
32. Active maintenance of mHDA2/mHDAC6 histone-deacetylase in the cytoplasm
33. HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor
34. Regulation of histone deacetylase 4 by binding of 14-3-3 proteins
35. SMRTe inhibits MEF2C transcriptional activation by targeting HDAC4 and 5 to nuclear domains
36. Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor
37. The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis
38. Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5
39. NF-AT activation requires suppression of Crm1-dependent export by calcineurin
40. 2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy