Cigarette Smoking Impairs the Therapeutic Response to Oral Corticosteroids in Chronic Asthma

American Journal of Respiratory and Critical Care Medicine

Volumn 168, Issue 11, 2003, Pages 1308-1311

  Chaudhuri, Rekha ^a   Livingston, Eric ^a   McMahon, Alex D ^a   Thomson, Lorna ^a   Borland, William ^a   Thomson, Neil C ^a,b  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b WESTERN INFIRMARY   (United Kingdom)

Author keywords

Asthma; Corticosteroid resistance; Smoking

Indexed keywords

CORTICOSTEROID; PLACEBO; PREDNISOLONE; SALBUTAMOL;

ARTICLE; ASTHMA; CIGARETTE SMOKING; CLINICAL ARTICLE; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG EFFICACY; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FUNCTION; MALE; PEAK EXPIRATORY FLOW; PREDICTION; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; ASTHMA; CHRONIC DISEASE; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; DRUG RESISTANCE; FEMALE; GLUCOCORTICOIDS; HUMANS; MALE; MIDDLE AGED; PREDNISOLONE; PULMONARY VENTILATION; SMOKING;

EID: 0242537115     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.200304-503OC     Document Type: Article

References (29)

1. Althuis MD, Sexton M, Prybylski D. Cigarette smoking and asthma symptom severity among adult asthmatics. J Asthma 1999;36:257-264.
2. Siroux V, Pin I, Oryszczyn MP, Le Moual N, Kauffmann F. Relationships of active smoking to asthma and asthma severity in the EGEA study. Eur Respir J 2000;15:470-477.
3. Silverman RA, Boudreaux ED, Woodruff PG, Clark S, Camargo CA Jr. Cigarette smoking among asthmatic adults presenting to 64 emergency departments. Chest 2003;123:1472-1479.
4. Lange P, Parner J, Vestbo J, Schnohr P, Jensen G. A 15-year follow-up study of ventilatory function in adults with asthma. N Engl J Med 1998; 339:1194-1200.
5. Sippel JM, Pedula K, Vollmer WM, Buist S, Osborne ML. Associations of smoking with hospital-based care and quality of life in patients with obstructive airway disease. Chest 1999;115:691-696.
6. Marquette CH, Saulnier F, Leroy O, Wallaert B, Chopin C, Demarcq JM, Durocher A, Tonnel AB. Long-term prognosis of near-fatal asthma. Am Rev Respir Dis 1992;146:76-81.
7. Global initiative for asthma: global strategy for asthma management and prevention. Bethesda, MD: NHLBI/WHO Report; 1995. p. 95-3695.
8. Chalmers GW, Macleod KJ, Little SA, Thomson LJ, McSharry CP, Thomson NC. Influence of cigarette smoking on inhaled corticosteroid treatment in mild asthma. Thorax 2002;57:226-230.
9. Pedersen B, Dahl R, Karlstrom R, Peterson CG, Venge P. Eosinophil and neutrophil activity in asthma in a one-year trial with inhaled budesonide: the impact of smoking. Am J Respir Crit Care Med 1996; 153:1519-1529.
10. Chaudhuri R, Livingston E, Thomson L, McSharry C, Macleod K, McMahon AD, Thomson NC. Effect of cigarette smoking on the therapeutic response to oral corticosteroids in chronic asthma [abstract]. Am J Respir Crit Care Med 2003;167:A956.
11. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma: American Thoracic Society. Am Rev Respir Dis 1987;136:225-234.
12. Guidelines for the evaluation of impairment/disability in patients with asthma: American Thoracic Society. Am Rev Respir Dis 1993;147:1056-1061.
13. Johansson SGO, Hourihane JO'B, Bousquet J, Bruijnzeel-Koomen C, Dreborg S, Haahtela T, Kowalski ML, Mygind N, Ring J, van Cauwenberge P, et al. A revised nomenclature for allergy: an EAACI position statement from the EAACI nomenclature task force. Allergy 2001;56: 813-849.
14. Juniper EF, O'Byrne PM, Guyatt GH, Ferrie PJ, King DR. Development and validation of a questionnaire to measure asthma control. Eur Respir J 1999;14:902-907.
15. Santanello NC, Barber BL, Reiss TF, Friedman BS, Juniper EF, Zhang J. Measurement characteristics of two asthma symptom diary scales for use in clinical trials. Eur Respir J 1997;10:646-651.
16. Senn S. Cross-over trials in clinical research, 2nd ed. Chichester, UK: Wiley; 2002.
17. Kamada AK, Leung DYM, Gleason MC, Hill MR, Szefler SJ. High dose systemic glucocorticoid therapy in the treatment of asthma: a case of resistance and patterns of response. J Allergy Clin Immunol 1992;90: 685-687.
18. Lee TH, Brattsand R, Leung DYM. Corticosteroid action and resistance in asthma. Am J Respir Cell Mol Biol 1996;154(2 Pt 2):S1-S79.
19. Meijer RJ, Postma DS, Kauffman HF, Arends LR, Koeter GH, Kerstjens HAM. Accuracy of eosinophils and eosinophil cationic protein to predict steroid improvement in asthma. Clin Exp Allergy 2002;32:1096-1103.
20. Green RH, Brightling CE, Woltmann G, Parker D, Wardlaw AJ, Pavord ID. Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids. Thorax 2002;57:875-879.
21. Chalmers GW, MacLeod KJ, Thomson LJ, Little SA, McSharry CP, Thomson NC. Smoking and airway inflammation in patients with mild asthma. Chest 2001;120:1917-1922.
22. Turato G, Di Stefano A, Maestrelli P, Mapp CE, Ruggieri MP, Roggen A, Fabbri LM. Effect of smoking cessation on airway inflammation in chronic bronchitis. Am J Respir Crit Care Med 1995;152:1262-1267.
23. Churg A, Dai J, Tai H, Xie C, Wright JL. Tumor necrosis factor-α is central to acute cigarette smoke-induced inflammation and connective tissue breakdown. Am J Respir Crit Care Med 2002;166:849-854.
24. Webster JC, Oakley RH, Jewell CM, Cidlowski JA. Pro-inflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative b isoform: a mechanism for the generation of glucocorticoid resistance. Proc Natl Acad Sci USA 2001;98:6865-3870.
25. Byron KA, Varigos GA, Wootton AM. IL-4 production is increased in cigarette smokers. Clin Exp Immunol 1994;95:333-336.
26. 1 integrin-dependent mechanism. J Immunol 2003;170:795-504.
27. Bantel H, Schmitz ML, Raible A, Gregor M, Schulze-Osthoff K. Critical role of NF-kappaB and stress-activated protein kinases in steroid unresponsiveness. FASEB J 2002;16:1832-1834.
28. Ito K, Caramori G, Lim S, Oates T, Chung KF, Barnes PJ, Adcock IM. Expression and activity of histone deacetylases in human asthmatic airways. Am J Respir Crit Care Med 2002;166:392-396.
29. Ito K, Lim J, Caramori G, Chung K, Barnes P, Adcock IM. Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages. FASEB J 2001;15:1110-1112.