DNA cleavage of a cryptic recombination signal sequence by RAG1 and RAG2: Implications for partial VH gene replacement

Journal of Biological Chemistry

Volumn 281, Issue 18, 2006, Pages 12370-12380

  Rahman, Negar S ^a   Godderz, LeAnn J ^a   Stray, Stephen J ^b   Capra, J Donald ^b   Rodgers, Karla K ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; ANTIGENS; CELLS; DNA; SUBSTRATES;

CANONICAL RSS SUBSTRATES; LYMPHOCYTE; RECOMBINATION SIGNAL SEQUENCES (RSS); SUBSTRATE SEQUENCE;

GENETIC ENGINEERING;

DOUBLE STRANDED DNA; RAG1 PROTEIN; RAG2 PROTEIN;

ARTICLE; CATALYSIS; CRYPTIC (ERA); DNA CLEAVAGE; GENOMICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

BASE SEQUENCE; DNA; DNA-BINDING PROTEINS; ESCHERICHIA COLI; HOMEODOMAIN PROTEINS; HUMANS; LYMPHOCYTES; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; NUCLEOTIDES; RECOMBINATION, GENETIC; SUBSTRATE SPECIFICITY; VDJ RECOMBINASES;

EID: 33744958663     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M507906200     Document Type: Article

References (54)

1. Lewis, S. M. (1994) Adv. Immunol. 56, 27-150
2. Bassing, C., Swat, W., and Alt, F. (2002) Cell 109, (suppl.) S45-S55
3. Gellert, M. (2002) Annu. Rev. Biochem. 71, 101-132
4. Fugmann, S. D., Lee, A. I., Shockett, P. E., Villey, I. J., and Schatz, D. G. (2000) Annu. Rev. Immunol. 18, 495-527
5. Hesslein, D., and Schatz, D. (2001) Adv. Immunol. 78, 169-232
6. de Villartay, J. P., Fischer, A., and Durandy, A. (2003) Nat. Rev. Immunol. 3, 962-972
7. McBlane, J. F., van Gent, D. C., Ramsden, D. A., Romeo, C., Cuomo, C. A., Gellert, M., and Oettinger, M. A. (1995) Cell 83, 387-395
8. Eastman, Q. M., and Schatz, D. G. (1997) Nucleic Acids Res. 25, 4370-4378
9. Yu, K., and Lieber, M. R. (2000) Mol. Cell. Biol. 20, 7914-7921
10. Casellas, R., Shih, T., Kleinewietfeld, M., Rakonjac, J., Nemazee, D., Rajewsky, K., and Nussenzweig, M. (2001) Science 291, 1503-1505
11. Nemazee, D., and Hogquist, K. (2003) Curr. Opin. Immunol. 15, 182-189
12. Radic, M., and Zouali, M. (1996) Immunity 5, 505-511
13. Zhang, Z., Zemlin, M., Wang, Y. H., Munfus, D., Huye, L. E., Findley, H. W., Bridges, L. S., Roth, D. B., Burrows, P. D., and Cooper, M. D. (2003) Immunity 19, 21-31
14. Kouskoff, V., and Nemazee, D. (2001) Life Sci. 69, 1105-1113
15. Wilson, P. C., Wilson, K., Liu, Y. J., Banchereau, J., Pascual, V., and Capra, J. D. (2000) J. Exp. Med. 191, 1881-1894
16. Itoh, K., Meffre, E., Albesiano, E., Farber, A., Dines, D., Stein, P., Asnis, S., Furie, R., Jain, R., and Chiorazzi, N. (2000) J. Exp. Med. 192, 1151-1164
17. Kolar, G. R., and Capra, J. D. (2004) Scand. J. Immunol. 60, 108-111
18. Lenze, D., Greiner, A., Knorr, C., Anagnostopoulos, I., Stein, H., and Hummel, M. (2003) Mol. Pathol. 56, 249-255
19. Bellan, C., Lazzi, S., Zazzi, M., Lalinga, A. V., Palummo, N., Galieni, P., Marafioti, T., Tonini, T., Cinti, C., Leoncini, L., Pileri, S. A., and Tosi, P. (2002) Diagn. Mol. Pathol. 11, 2-8
20. Jankovic, M., Casellas, R., Yannoutsos, N., Wardemann, H., and Nussenzweig, M. (2004) Annu. Rev. Immunol. 22, 485-501
21. Hillion, S., Rochas, C., Youinou, P., and Jamin, C. (2005) Ann. N. Y. Acad. Sci. 1050, 10-18
22. Darlow, J. M., and Stott, D. I. (2005) Immunology 114, 155-165
23. Arbuckle, J. L., Fauss, L. J., Simpson, R., Ptaszek, L. M., and Rodgers, K. K. (2001) J. Biol. Chem. 276, 37093-37101
24. Spanopoulou, E., Zaitseva, F., Wang, F.-H., Santagata, S., Baltimore, D., and Panayotou, G. (1996) Cell 87, 263-276
25. Godderz, L. J., Rahman, N. S., Risinger, G. M., Arbuckle, J. L., and Rodgers, K. K. (2003) Nucleic Acids Res. 31, 2014-2023
26. Swanson, P. C. (2002) Mol. Cell. Biol. 22, 1340-1351
27. Santagata, S., Aidinis, V., and Spanopoulou, E. (1998) J. Biol. Chem. 273, 16325-16331
28. Besmer, E., Mansilla-Soto, J., Cassard, S., Sawchuk, D. J., Brown, G., Sadofsky, M., Lewis, S. M., Nussenzweig, M. C., and Cortes, P. (1998) Mol. Cell 2, 817-828
29. Shockett, P. E., and Schatz, D. G. (1999) Mol. Cell. Biol. 19, 4159-4166
30. Ramsden, D. A., McBlane, J. F., van Gent, D. C., and Gellert, M. (1996) EMBO J. 15, 3197-3206
31. Cuomo, C. A., Mundy, C. L., and Oettinger, M. A. (1996) Mol. Cell. Biol. 16, 5683-5690
32. Melek, M., Gellert, M., and van Gent, D. C. (1998) Science 280, 301-303
33. Agrawal, A., Eastman, Q. M., and Schatz, D. G. (1998) Nature 394, 744-751
34. Hiom, K., Melek, M., and Gellert, M. (1998) Cell 94, 463-470
35. Shih, I.-H., Melek, M., Jayaratne, N. D., and Gellert, M. (2002) EMBO J. 21, 6625-6633
36. Santagata, S., Besmer, E., Villa, A., Bozzi, F., Allingham, J. S., Sobacchi, C., Haniford, D. B., Vezzoni, P., Nussenzweig, M. C., Pan, Z.-Q., and Cortes, P. (1999) Mol. Cell 4, 935-947
37. Raghavan, S. C., Swanson, P. C., Ma, Y., and Lieber, M. R. (2005) Mol. Cell. Biol. 25, 5904-5919
38. Neiditch, M. B., Lee, G. S., Huye, L. E., Brandt, V. L., and Roth, D. B. (2002) Mol. Cell 9, 871-878
39. Greaves, M. F., and Wiemels, J. (2003) Nat. Rev. Cancer 3, 639-649
40. Cowell, L. G., Davila, M., Yang, K., Kepler, T. B., and Kelsoe, G. (2003) J. Exp. Med. 197, 207-220
41. Lee, A. I., Fugmann, S. D., Cowell, L. G., Ptaszek, L. M., Kelsoe, G., and Schatz, D. G. (2003) PLoS Biol. 1, 56-69
42. Montalbano, A., Ogwara, K. M., Tang, A., Matthews, A. G., Larijani, M., Oettinger, M. A., and Feeney, A. J. (2003) J. Immunol. 171, 5296-5304
43. Ezekiel, U., Sun, T., Bozek, G., and Storb, U. (1997) Mol. Cell. Biol. 17, 4191-4197
44. Yu, K., and Lieber, M. R. (1999) Mol. Cell. Biol. 19, 8094-8102
45. Gerstein, R. M., and Lieber, M. R. (1993) Genes Dev. 7, 1459-1469
46. Zhang, Z., Burrows, P. D., and Cooper, M. D. (2004) Immunol. Rev. 197, 231-242
47. Swanson, P. C., and Desiderio, S. (1998) Immunity 9, 115-125
48. Akamatsu, Y., and Oettinger, M. A. (1998) Mol. Cell. Biol. 18, 4670-4678
49. Peak, M. M., Arbuckle, J. L., and Rodgers, K. K. (2003) J. Biol. Chem. 278, 18235-18240
50. De, P., Peak, M. M., and Rodgers, K. K. (2004) Mol. Cell. Biol. 24, 6850-6860
51. De, P., and Rodgers, K. K. (2004) Immunol. Rev. 200, 70-82
52. Lee, G. S., Neiditch, M. B., Salus, S. S., and Roth, D. B. (2004) Cell 117, 171-184
53. Weinstock, D. M., and Jasin, M. (2006) Mol. Cell. Biol. 26, 131-139
54. Lewis, S. M., Agard, E., Suh, S., and Czyzyk, L. (1997) Mol. Cell. Biol. 17, 3125-3136