Nicking is asynchronous and stimulated by synapsis in 12/23 rule-regulated V(D)J cleavage

Nucleic Acids Research

Volumn 25, Issue 21, 1997, Pages 4370-4378

  Eastman, Quinn M ^a   Schatz, David G ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME PAIRING; DNA CLEAVAGE; DNA NICK TRANSLATION; DNA SEQUENCE; GENE SEQUENCE; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN STRUCTURE; IMMUNOGLOBULIN VARIABLE REGION; PRIORITY JOURNAL;

DNA; DNA-BINDING PROTEINS; GENE REARRANGEMENT; HOMEODOMAIN PROTEINS; MANGANESE; OLIGODEOXYRIBONUCLEOTIDES; POINT MUTATION; RECOMBINATION, GENETIC;

EID: 0030678531     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/25.21.4370     Document Type: Article

References (43)

1. Ramsden, D.A., Baetz, K. and Wu, G.E. (1994) Nucleic Acids Res., 22, 1785-1796.
2. Hesse, J.E., Lieber, M.R., Mizuuchi, K. and Gellert, M. (1989) Genes Dev., 3, 1053-1061.
3. Lewis, S.M. and Hesse, J.E. (1991) EMBO J., 10, 3631-3639.
4. Lewis, S.M. (1994) Adv. Immunol., 56, 27-150.
5. McBlane, J.F., van Gent, D.C., Ramsden, D.A., Romeo, C., Cuomo, C.A., Gellert, M. and Oettinger, M.A. (1995) Cell, 83, 387-395.
6. van Gent, D.C., Mizuuchi, K. and Gellert, M. (1996) Science, 271, 1592-1594.
7. Roth, D.B., Menetski, J.P. Nakajima, P.B., Bosma, M.J. and Gellert, M. (1992) Cell, 70, 983-991.
8. Roth, D.B., Nakajima, P.B., Menetski, J.P. Bosma, M.J. and Gellert, M. (1992) Cell, 69, 41-53.
9. Ramsden, D.A. and Gellert, M. (1995) Genes Dev., 9, 2409-2420.
10. Zhu, C.M. and Roth, D.B. (1995) Immunity, 2, 101-112.
11. Livak, F. and Schatz, D.G. (1997) J. Mol. Biol., 267, 1-9.
12. Schlissel, M., Constantinescu, A., Morrow, T., Baxter, M. and Peng, A. (1993) Genes Dev., 7, 2520-2532.
13. Taccioli, G.E., Gottlieb, T.M., Blunt, T., Priestley, A., Demengeot, J., Mizuta, R., Lehmann, A.R., Alt, F.W., Jackson, S.P. and Jeggo, P.A. (1994) Science, 265, 1442-1445.
14. Smider, V., Rathmell, W.K., Lieber, M.R. and Chu, G. (1994) Science, 266, 288-291.
15. Zhu, C.M., Bogue, M.A., Lim, D.S., Hasty, P. and Roth, D.B. (1996) Cell, 86, 379-389.
16. Kirchgessner, C.U., Patil, C.K., Evans, J.W., Cuomo, C.A., Fried, L.M., Carter, T., Oettinger, M.A. and Brown, J.M. (1995) Science, 267, 1178-1183.
17. Blunt, T., Finnie, N.J., Taccioli, G.E., Smith, G.C.M., Demengeot, J., Gottlieb, T.M., Mizuta, R., Varghese, A.J., Alt, F.W., Jeggo, P.A. and Jackson, S.P. (1995) Cell, 80, 813-823.
18. Steen, S.B., Gomelsky, L. and Roth, D.B. (1996) Genes Cells, 1, 543-553.
19. Eastman, Q.M., Leu, T.M.J. and Schatz, D.G. (1996) Nature, 380, 85-88.
20. van Gent, D.C., Ramsden, D.A. and Gellert, M. (1996) Cell, 85, 107-113.
21. Sawchuk, D.J., Weis-Garcia, F., Malik, S., Besmer, E., Bustin, M., Nussenzweig, M.C. and Cortes, P. (1997) J. Exp. Med., 185, 2025-2032.
22. van Gent, D.C., Hiom, K., Paull, T.T. and Gellert, M. (1997) EMBO J., 16, 2665-2670.
23. Cuomo, C.A., Mundy, C.L. and Oettinger, M.A. (1996) Mol. Cell. Biol., 16, 5683-5690.
24. Ramsden, D.A., McBlane, J.R. van Gent, D.C. and Gellert, M. (1996) EMBO J., 15, 3197-3206.
25. Agrawal, A. and Schatz, D.G. (1997) Cell, 89, 43-53.
26. Hesse, J.E., Lieber, M.R., Gellert, M. and Mizuuchi, K. (1987) Cell, 49, 775-783.
27. Sheehan, K.M. and Lieber, M.R. (1993) Mol. Cell. Biol., 13, 1363-1370.
28. Thompson, C.B. (1995) Immunity, 3, 531-539.
29. Lewis, S.M. and Wu, G.E. (1997) Cell, 88, 159-162.
30. Sakai, J., Chalmers, R.H. and Kleckner, N. (1995) EMBO J., 14, 4374-4383.
31. Gary, P.A., Biery, M.C., Bainton, R.J. and Craig, N.L. (1996) J. Mol. Biol., 257, 301-316.
32. Savilahti, H. and Mizuuchi, K. (1996) Cell, 85, 271-80.
33. Bainton, R., Gamas, P. and Craig, N.L. (1991) Cell, 65, 805-816.
34. Haniford, D.B. and Kleckner, N. (1994) EMBO J., 13, 3401-3411.
35. Baker, T.A. and Luo, L. (1994) Proc. Natl. Acad. Sci. USA, 91, 6654-6658
36. Bolland, S. and Kleckner, N. (1996) Cell, 84, 223-233.
37. Rice, P. and Mizuuchi, K. (1995) Cell, 82, 209-220.
38. Sadofsky, M.J., Hesse, J.E., van Gent, D.C. and Gellert, M. (1995) Genes Dev., 9, 2193-2199.
39. Rodgers, K.K., Bu, Z., Fleming, K.G., Schatz, D.G., Engelman, D.M. and Coleman, J.E. (1996) J. Mol. Biol., 260, 70-84.
40. Difilippantonio, M.J., McMahan, C.J., Eastman, Q.M., Spanopoulou, E. and Schatz, D.G. (1996) Cell, 87, 253-262.
41. Spanopoulou, E., Zaitseva, F., Wang, F.-H., Santagata, S., Baltimore, D. and Panayotou, G. (1996) Cell, 87, 263-276.
42. Schatz, D.G. and Leu, T.M.J. (1996) In Jessberger, R. and Lieber, M.R. (eds), Molecular Analysis of DNA Rearrangements in the Immune System, Springer-Verlag, Heidelberg, Germany, Vol. 217, pp. 11-29.
43. Hiom, K. and Gellert, M. (1997) Cell, 88, 65-72.