메뉴 건너뛰기




Volumn 37, Issue 6, 2003, Pages 1405-1413

Oxidant-induced hepatocyte injury from menadione is regulated by ERK and AP-1 signaling

Author keywords

[No Author keywords available]

Indexed keywords

MENADIONE; MITOGEN ACTIVATED PROTEIN KINASE; OXIDIZING AGENT; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

EID: 0038580372     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2003.50233     Document Type: Article
Times cited : (120)

References (42)
  • 1
    • 0032921559 scopus 로고    scopus 로고
    • Can antioxidant vitamins materially reduce oxidative damage in humans?
    • McCall MR, Frei B. Can antioxidant vitamins materially reduce oxidative damage in humans? Free Radic Biol Med 1999;26:1034-1053.
    • (1999) Free Radic Biol Med , vol.26 , pp. 1034-1053
    • McCall, M.R.1    Frei, B.2
  • 2
    • 0025314685 scopus 로고
    • Role of oxygen free radicals in carcinogenesis and brain ischemia
    • Floyd RA. Role of oxygen free radicals in carcinogenesis and brain ischemia. FASEB J 1990;4:2587-2597.
    • (1990) FASEB J , vol.4 , pp. 2587-2597
    • Floyd, R.A.1
  • 3
    • 0031789130 scopus 로고    scopus 로고
    • Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor
    • Colell A, Garcia-Ruiz C, Miranda M, Ardite E, Mari M, Morales A, Corrales F, et al. Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor. Gastroenterology 1998;115:1541-1551.
    • (1998) Gastroenterology , vol.115 , pp. 1541-1551
    • Colell, A.1    Garcia-Ruiz, C.2    Miranda, M.3    Ardite, E.4    Mari, M.5    Morales, A.6    Corrales, F.7
  • 4
    • 0031749682 scopus 로고    scopus 로고
    • Redox gene therapy for ischemia/reperfusion injury of the liver reduces AP1 and NF-κB activation
    • Zwacka RM, Zhou W, Zhang Y, Darby CJ, Dudus L, Hallorson J, Oberley L, et al. Redox gene therapy for ischemia/reperfusion injury of the liver reduces AP1 and NF-κB activation. Nat Med 1998;4:698-704.
    • (1998) Nat Med , vol.4 , pp. 698-704
    • Zwacka, R.M.1    Zhou, W.2    Zhang, Y.3    Darby, C.J.4    Dudus, L.5    Hallorson, J.6    Oberley, L.7
  • 5
    • 0036828064 scopus 로고    scopus 로고
    • Peroxynitrite is a critical mediator of acetaminophen hepatotoxicity in murine livers: Protection by glutathione
    • Knight TR, Ho YS, Farhood A, Jaeschke H. Peroxynitrite is a critical mediator of acetaminophen hepatotoxicity in murine livers: protection by glutathione. J Pharmacol Exp Ther 2002;303:468-475.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 468-475
    • Knight, T.R.1    Ho, Y.S.2    Farhood, A.3    Jaeschke, H.4
  • 6
    • 0035933837 scopus 로고    scopus 로고
    • Nonstructural 3 protein of hepatitis C virus triggers an oxidative burst in human monocytes via activation of NADPH oxidase
    • Bureau C, Bernad J, Chaouche N, Orfila C, Beraud M, Gonindard C, Alric L, et al. Nonstructural 3 protein of hepatitis C virus triggers an oxidative burst in human monocytes via activation of NADPH oxidase. J Biol Chem 2001;276:23077-23083.
    • (2001) J Biol Chem , vol.276 , pp. 23077-23083
    • Bureau, C.1    Bernad, J.2    Chaouche, N.3    Orfila, C.4    Beraud, M.5    Gonindard, C.6    Alric, L.7
  • 7
    • 0029854544 scopus 로고    scopus 로고
    • Free radicals, proteins and DNA: Oxidative damage versus redox regulation
    • Halliwell B. Free radicals, proteins and DNA: oxidative damage versus redox regulation. Biochem Soc Trans 1996;24:1023-1027.
    • (1996) Biochem Soc Trans , vol.24 , pp. 1023-1027
    • Halliwell, B.1
  • 9
    • 0036775096 scopus 로고    scopus 로고
    • Induction and regulation of hepatocyte apoptosis by oxidative stress
    • Czaja MJ. Induction and regulation of hepatocyte apoptosis by oxidative stress. Antiox Redox Signal 2002;4:759-768.
    • (2002) Antiox Redox Signal , vol.4 , pp. 759-768
    • Czaja, M.J.1
  • 10
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signaling cascades
    • Chang L, Karin M. Mammalian MAP kinase signaling cascades. Nature 2001;410:37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 11
    • 0032527705 scopus 로고    scopus 로고
    • The cellular response to oxidative stress: Influences of mitogen-activated protein kinase signalling pathways on cell survival
    • Wang X, Martindale JL, Liu Y, Holbrook NJ. The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival. Biochem J 1998;333:291-300.
    • (1998) Biochem J , vol.333 , pp. 291-300
    • Wang, X.1    Martindale, J.L.2    Liu, Y.3    Holbrook, N.J.4
  • 13
    • 0034604540 scopus 로고    scopus 로고
    • Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress
    • Kurata S-I. Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress. J Biol Chem 2000;275:23413-23416.
    • (2000) J Biol Chem , vol.275 , pp. 23413-23416
    • Kurata, S.-I.1
  • 15
    • 0020440918 scopus 로고
    • The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes
    • Thort H, Smith MT, Hartzell P, Bellomo G, Jewell SA, Orrenius S. The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. J Biol Chem 1982;257:12419-12425.
    • (1982) J Biol Chem , vol.257 , pp. 12419-12425
    • Thort, H.1    Smith, M.T.2    Hartzell, P.3    Bellomo, G.4    Jewell, S.A.5    Orrenius, S.6
  • 16
    • 0020967289 scopus 로고
    • Temperature-sensitive adult liver cell line dependent on glucocorticoid for differentiation
    • Chou JY. Temperature-sensitive adult liver cell line dependent on glucocorticoid for differentiation. Mol Cell Biol 1983;3:1013-1020.
    • (1983) Mol Cell Biol , vol.3 , pp. 1013-1020
    • Chou, J.Y.1
  • 17
  • 18
    • 0022445670 scopus 로고
    • Rapid colorimetric assay for cell growth and survival
    • Denizat F, Lang R. Rapid colorimetric assay for cell growth and survival. J Immunol Methods 1986;89:271-277.
    • (1986) J Immunol Methods , vol.89 , pp. 271-277
    • Denizat, F.1    Lang, R.2
  • 19
    • 0034614526 scopus 로고    scopus 로고
    • Hepatocytes sensitized to tumor necrosis factor-α cytotoxicity undergo apoptosis through caspase-dependent and caspase-independent pathways
    • Jones BE, Lo CR, Liu H, Srinivasan A, Streetz K, Valentino KL, Czaja MJ. Hepatocytes sensitized to tumor necrosis factor-α cytotoxicity undergo apoptosis through caspase-dependent and caspase-independent pathways. J Biol Chem 2000;275:705-712.
    • (2000) J Biol Chem , vol.275 , pp. 705-712
    • Jones, B.E.1    Lo, C.R.2    Liu, H.3    Srinivasan, A.4    Streetz, K.5    Valentino, K.L.6    Czaja, M.J.7
  • 20
    • 0030051257 scopus 로고    scopus 로고
    • The induction of hepatoma cell apoptosis by c-myc requires zinc and occurs in the absence of DNA fragmentation
    • Xu J, Xu Y, Nguyen Q, Novikoff PM, Czaja MJ. The induction of hepatoma cell apoptosis by c-myc requires zinc and occurs in the absence of DNA fragmentation. Am J Physiol 1996;270:G60-G70.
    • (1996) Am J Physiol , vol.270
    • Xu, J.1    Xu, Y.2    Nguyen, Q.3    Novikoff, P.M.4    Czaja, M.J.5
  • 21
    • 0034041406 scopus 로고    scopus 로고
    • Role of caspases and NF-κB signaling in hydrogen peroxide- and superoxide-induced hepatocyte apoptosis
    • Jones BE, Lo CR, Liu H, Pradhan Z, Garcia L, Srinivasan A, Valentino KL, et al. Role of caspases and NF-κB signaling in hydrogen peroxide- and superoxide-induced hepatocyte apoptosis. Am J Physiol 2000;278:G693-G699.
    • (2000) Am J Physiol , vol.278
    • Jones, B.E.1    Lo, C.R.2    Liu, H.3    Pradhan, Z.4    Garcia, L.5    Srinivasan, A.6    Valentino, K.L.7
  • 24
    • 0034704116 scopus 로고    scopus 로고
    • Inhibition of c-Myc expression sensitizes hepatocytes to tumor necrosis factor-induced apoptosis and necrosis
    • Liu H, Lo CR, Jones BE, Pradhan Z, Srinivasan A, Valentino KL, Stockert RJ, et al. Inhibition of c-Myc expression sensitizes hepatocytes to tumor necrosis factor-induced apoptosis and necrosis. J Biol Chem 2000;275:40155-40162.
    • (2000) J Biol Chem , vol.275 , pp. 40155-40162
    • Liu, H.1    Lo, C.R.2    Jones, B.E.3    Pradhan, Z.4    Srinivasan, A.5    Valentino, K.L.6    Stockert, R.J.7
  • 25
  • 27
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 1995;270:27489-27494.
    • (1995) J Biol Chem , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 28
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 2000;351:95-105.
    • (2000) Biochem J , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 29
    • 0036009411 scopus 로고    scopus 로고
    • NF-κB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun
    • Liu H, Lo CR, Czaja MJ. NF-κB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun. HEPATOLOGY 2002;35:772-778.
    • (2002) Hepatology , vol.35 , pp. 772-778
    • Liu, H.1    Lo, C.R.2    Czaja, M.J.3
  • 30
    • 0036086898 scopus 로고    scopus 로고
    • Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun mediated cell death from TNF-α
    • Liu H, Jones BE, Bradham C, Czaja MJ. Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun mediated cell death from TNF-α. Am J Physiol 2002;282:G257-G266.
    • (2002) Am J Physiol , vol.282
    • Liu, H.1    Jones, B.E.2    Bradham, C.3    Czaja, M.J.4
  • 31
    • 0034607702 scopus 로고    scopus 로고
    • Requirement of JNK for stress induced activation of the cytochrome c-mediated death pathway
    • Tournier C, Hess P, Yang DD, Xu J, Turner TK, Nimnual A, Bar-Sagi D, et al. Requirement of JNK for stress induced activation of the cytochrome c-mediated death pathway. Science 2000;288:870-874.
    • (2000) Science , vol.288 , pp. 870-874
    • Tournier, C.1    Hess, P.2    Yang, D.D.3    Xu, J.4    Turner, T.K.5    Nimnual, A.6    Bar-Sagi, D.7
  • 33
    • 0030886770 scopus 로고    scopus 로고
    • Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats
    • Aikawa R, Komuro I, Yamazaki T, Zou Y, Kudoh S, Tanaka M, Shiojima I, et al. Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats. J Clin Invest 1997;100:1813-1821.
    • (1997) J Clin Invest , vol.100 , pp. 1813-1821
    • Aikawa, R.1    Komuro, I.2    Yamazaki, T.3    Zou, Y.4    Kudoh, S.5    Tanaka, M.6    Shiojima, I.7
  • 34
    • 0037172997 scopus 로고    scopus 로고
    • Ebselen: A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant
    • Zhao R, Masayasu H, Holmgren A. Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant. Proc Natl Acad Sci U S A 2002;99:8579-8584.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 8579-8584
    • Zhao, R.1    Masayasu, H.2    Holmgren, A.3
  • 35
    • 0036151709 scopus 로고    scopus 로고
    • Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes
    • Rao Y-P, Studer EJ, Stravitz RT, Gupta S, Qiao L, Dent P, Hylemon PB. Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes. HEPATOLOGY 2002;35:307-314.
    • (2002) Hepatology , vol.35 , pp. 307-314
    • Rao, Y.-P.1    Studer, E.J.2    Stravitz, R.T.3    Gupta, S.4    Qiao, L.5    Dent, P.6    Hylemon, P.B.7
  • 36
    • 0036211298 scopus 로고    scopus 로고
    • Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes
    • Qiao L, Yacoub A, Studer E, Gupta S, Pei XY, Grant S, Hylemon PB, et al. Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes. HEPATOLOGY 2002;35:779-789.
    • (2002) Hepatology , vol.35 , pp. 779-789
    • Qiao, L.1    Yacoub, A.2    Studer, E.3    Gupta, S.4    Pei, X.Y.5    Grant, S.6    Hylemon, P.B.7
  • 37
    • 0036241214 scopus 로고    scopus 로고
    • Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner
    • Graf D, Kurz AK, Fischer R, Reinehr R, Häussinger D. Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner. Gastroenterology 2002;122:1411-1427.
    • (2002) Gastroenterology , vol.122 , pp. 1411-1427
    • Graf, D.1    Kurz, A.K.2    Fischer, R.3    Reinehr, R.4    Häussinger, D.5
  • 38
    • 0032698075 scopus 로고    scopus 로고
    • Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
    • Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 1999;286:1358-1362.
    • (1999) Science , vol.286 , pp. 1358-1362
    • Bonni, A.1    Brunet, A.2    West, A.E.3    Datta, S.R.4    Takasu, M.A.5    Greenberg, M.E.6
  • 39
    • 0033970533 scopus 로고    scopus 로고
    • Dual specificity phosphatases: A gene family for control of MAP kinase function
    • Camps M, Nichols A, Arkinstall S. Dual specificity phosphatases: a gene family for control of MAP kinase function. FASEB J 1999;14:6-16.
    • (1999) FASEB J , vol.14 , pp. 6-16
    • Camps, M.1    Nichols, A.2    Arkinstall, S.3
  • 40
    • 0033559005 scopus 로고    scopus 로고
    • Redox-sensitive protein phosphatase activity regulates the phosphorylation state of p38 protein kinase in primary astrocyte culture
    • Robinson KA, Stewart CA, Pye QN, Nguyen X, Kenney L, Salzman S, Floyd RA, et al. Redox-sensitive protein phosphatase activity regulates the phosphorylation state of p38 protein kinase in primary astrocyte culture. J Neurosci Res 1999;55:724-732.
    • (1999) J Neurosci Res , vol.55 , pp. 724-732
    • Robinson, K.A.1    Stewart, C.A.2    Pye, Q.N.3    Nguyen, X.4    Kenney, L.5    Salzman, S.6    Floyd, R.A.7
  • 41
    • 0034672131 scopus 로고    scopus 로고
    • Compartment-specific regulation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) mitogen-activated protein kinases (MAPKs) by ERK-dependent and non-ERK-dependent inductions of MAPK phosphatase (MKP)-3 and MKP-1 in differentiating P19 cells
    • Reffas S, Schlegel W. Compartment-specific regulation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) mitogen-activated protein kinases (MAPKs) by ERK-dependent and non-ERK-dependent inductions of MAPK phosphatase (MKP)-3 and MKP-1 in differentiating P19 cells. Biochem J 2000;352:701-708.
    • (2000) Biochem J , vol.352 , pp. 701-708
    • Reffas, S.1    Schlegel, W.2
  • 42
    • 0031005579 scopus 로고    scopus 로고
    • Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases
    • Bradham CA, Stachlewitz RF, Gao W, Qian T, Jayadev S, Jenkins G, Hannun Y, et al. Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. HEPATOLOGY 1997;25:1128-1135.
    • (1997) Hepatology , vol.25 , pp. 1128-1135
    • Bradham, C.A.1    Stachlewitz, R.F.2    Gao, W.3    Qian, T.4    Jayadev, S.5    Jenkins, G.6    Hannun, Y.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.