-
1
-
-
0032921559
-
Can antioxidant vitamins materially reduce oxidative damage in humans?
-
McCall MR, Frei B. Can antioxidant vitamins materially reduce oxidative damage in humans? Free Radic Biol Med 1999;26:1034-1053.
-
(1999)
Free Radic Biol Med
, vol.26
, pp. 1034-1053
-
-
McCall, M.R.1
Frei, B.2
-
2
-
-
0025314685
-
Role of oxygen free radicals in carcinogenesis and brain ischemia
-
Floyd RA. Role of oxygen free radicals in carcinogenesis and brain ischemia. FASEB J 1990;4:2587-2597.
-
(1990)
FASEB J
, vol.4
, pp. 2587-2597
-
-
Floyd, R.A.1
-
3
-
-
0031789130
-
Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor
-
Colell A, Garcia-Ruiz C, Miranda M, Ardite E, Mari M, Morales A, Corrales F, et al. Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor. Gastroenterology 1998;115:1541-1551.
-
(1998)
Gastroenterology
, vol.115
, pp. 1541-1551
-
-
Colell, A.1
Garcia-Ruiz, C.2
Miranda, M.3
Ardite, E.4
Mari, M.5
Morales, A.6
Corrales, F.7
-
4
-
-
0031749682
-
Redox gene therapy for ischemia/reperfusion injury of the liver reduces AP1 and NF-κB activation
-
Zwacka RM, Zhou W, Zhang Y, Darby CJ, Dudus L, Hallorson J, Oberley L, et al. Redox gene therapy for ischemia/reperfusion injury of the liver reduces AP1 and NF-κB activation. Nat Med 1998;4:698-704.
-
(1998)
Nat Med
, vol.4
, pp. 698-704
-
-
Zwacka, R.M.1
Zhou, W.2
Zhang, Y.3
Darby, C.J.4
Dudus, L.5
Hallorson, J.6
Oberley, L.7
-
5
-
-
0036828064
-
Peroxynitrite is a critical mediator of acetaminophen hepatotoxicity in murine livers: Protection by glutathione
-
Knight TR, Ho YS, Farhood A, Jaeschke H. Peroxynitrite is a critical mediator of acetaminophen hepatotoxicity in murine livers: protection by glutathione. J Pharmacol Exp Ther 2002;303:468-475.
-
(2002)
J Pharmacol Exp Ther
, vol.303
, pp. 468-475
-
-
Knight, T.R.1
Ho, Y.S.2
Farhood, A.3
Jaeschke, H.4
-
6
-
-
0035933837
-
Nonstructural 3 protein of hepatitis C virus triggers an oxidative burst in human monocytes via activation of NADPH oxidase
-
Bureau C, Bernad J, Chaouche N, Orfila C, Beraud M, Gonindard C, Alric L, et al. Nonstructural 3 protein of hepatitis C virus triggers an oxidative burst in human monocytes via activation of NADPH oxidase. J Biol Chem 2001;276:23077-23083.
-
(2001)
J Biol Chem
, vol.276
, pp. 23077-23083
-
-
Bureau, C.1
Bernad, J.2
Chaouche, N.3
Orfila, C.4
Beraud, M.5
Gonindard, C.6
Alric, L.7
-
7
-
-
0029854544
-
Free radicals, proteins and DNA: Oxidative damage versus redox regulation
-
Halliwell B. Free radicals, proteins and DNA: oxidative damage versus redox regulation. Biochem Soc Trans 1996;24:1023-1027.
-
(1996)
Biochem Soc Trans
, vol.24
, pp. 1023-1027
-
-
Halliwell, B.1
-
8
-
-
0034177958
-
Redox regulatory mechanisms of cellular signal transduction
-
Gabbita SP, Robinson KA, Stewart CA, Floyd RA, Hensley K. Redox regulatory mechanisms of cellular signal transduction. Arch Biochem Biophys 2000;376:1-13.
-
(2000)
Arch Biochem Biophys
, vol.376
, pp. 1-13
-
-
Gabbita, S.P.1
Robinson, K.A.2
Stewart, C.A.3
Floyd, R.A.4
Hensley, K.5
-
9
-
-
0036775096
-
Induction and regulation of hepatocyte apoptosis by oxidative stress
-
Czaja MJ. Induction and regulation of hepatocyte apoptosis by oxidative stress. Antiox Redox Signal 2002;4:759-768.
-
(2002)
Antiox Redox Signal
, vol.4
, pp. 759-768
-
-
Czaja, M.J.1
-
10
-
-
0035282334
-
Mammalian MAP kinase signaling cascades
-
Chang L, Karin M. Mammalian MAP kinase signaling cascades. Nature 2001;410:37-40.
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
11
-
-
0032527705
-
The cellular response to oxidative stress: Influences of mitogen-activated protein kinase signalling pathways on cell survival
-
Wang X, Martindale JL, Liu Y, Holbrook NJ. The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival. Biochem J 1998;333:291-300.
-
(1998)
Biochem J
, vol.333
, pp. 291-300
-
-
Wang, X.1
Martindale, J.L.2
Liu, Y.3
Holbrook, N.J.4
-
12
-
-
0034630186
-
Serine/threonine protein kinases and apoptosis
-
Cross TG, Scheel-Toellner D, Henriquez NV, Deacon E, Salmon M, Lord JM. Serine/threonine protein kinases and apoptosis. Exp Cell Res 2000;256:34-41.
-
(2000)
Exp Cell Res
, vol.256
, pp. 34-41
-
-
Cross, T.G.1
Scheel-Toellner, D.2
Henriquez, N.V.3
Deacon, E.4
Salmon, M.5
Lord, J.M.6
-
13
-
-
0034604540
-
Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress
-
Kurata S-I. Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress. J Biol Chem 2000;275:23413-23416.
-
(2000)
J Biol Chem
, vol.275
, pp. 23413-23416
-
-
Kurata, S.-I.1
-
14
-
-
0026515757
-
Contemporary issues in toxicology: Quinone chemistry and toxicity
-
Monks TJ, Hanzlik RP, Cohen GM, Ross D, Graham DG. Contemporary issues in toxicology: quinone chemistry and toxicity. Toxicol Appl Pharmacol 1992;112:2-16.
-
(1992)
Toxicol Appl Pharmacol
, vol.112
, pp. 2-16
-
-
Monks, T.J.1
Hanzlik, R.P.2
Cohen, G.M.3
Ross, D.4
Graham, D.G.5
-
15
-
-
0020440918
-
The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes
-
Thort H, Smith MT, Hartzell P, Bellomo G, Jewell SA, Orrenius S. The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. J Biol Chem 1982;257:12419-12425.
-
(1982)
J Biol Chem
, vol.257
, pp. 12419-12425
-
-
Thort, H.1
Smith, M.T.2
Hartzell, P.3
Bellomo, G.4
Jewell, S.A.5
Orrenius, S.6
-
16
-
-
0020967289
-
Temperature-sensitive adult liver cell line dependent on glucocorticoid for differentiation
-
Chou JY. Temperature-sensitive adult liver cell line dependent on glucocorticoid for differentiation. Mol Cell Biol 1983;3:1013-1020.
-
(1983)
Mol Cell Biol
, vol.3
, pp. 1013-1020
-
-
Chou, J.Y.1
-
17
-
-
0032185680
-
NF-κB inactivation converts a hepatocyte cell line TNF-α response from proliferation to apoptosis
-
Xu Y, Bialik S, Jones BE, Iimuro Y, Kitsis RN, Srinivasan A, Brenner DA, et al. NF-κB inactivation converts a hepatocyte cell line TNF-α response from proliferation to apoptosis. Am J Physiol 1998;275:C1058-C1066.
-
(1998)
Am J Physiol
, vol.275
-
-
Xu, Y.1
Bialik, S.2
Jones, B.E.3
Iimuro, Y.4
Kitsis, R.N.5
Srinivasan, A.6
Brenner, D.A.7
-
18
-
-
0022445670
-
Rapid colorimetric assay for cell growth and survival
-
Denizat F, Lang R. Rapid colorimetric assay for cell growth and survival. J Immunol Methods 1986;89:271-277.
-
(1986)
J Immunol Methods
, vol.89
, pp. 271-277
-
-
Denizat, F.1
Lang, R.2
-
19
-
-
0034614526
-
Hepatocytes sensitized to tumor necrosis factor-α cytotoxicity undergo apoptosis through caspase-dependent and caspase-independent pathways
-
Jones BE, Lo CR, Liu H, Srinivasan A, Streetz K, Valentino KL, Czaja MJ. Hepatocytes sensitized to tumor necrosis factor-α cytotoxicity undergo apoptosis through caspase-dependent and caspase-independent pathways. J Biol Chem 2000;275:705-712.
-
(2000)
J Biol Chem
, vol.275
, pp. 705-712
-
-
Jones, B.E.1
Lo, C.R.2
Liu, H.3
Srinivasan, A.4
Streetz, K.5
Valentino, K.L.6
Czaja, M.J.7
-
20
-
-
0030051257
-
The induction of hepatoma cell apoptosis by c-myc requires zinc and occurs in the absence of DNA fragmentation
-
Xu J, Xu Y, Nguyen Q, Novikoff PM, Czaja MJ. The induction of hepatoma cell apoptosis by c-myc requires zinc and occurs in the absence of DNA fragmentation. Am J Physiol 1996;270:G60-G70.
-
(1996)
Am J Physiol
, vol.270
-
-
Xu, J.1
Xu, Y.2
Nguyen, Q.3
Novikoff, P.M.4
Czaja, M.J.5
-
21
-
-
0034041406
-
Role of caspases and NF-κB signaling in hydrogen peroxide- and superoxide-induced hepatocyte apoptosis
-
Jones BE, Lo CR, Liu H, Pradhan Z, Garcia L, Srinivasan A, Valentino KL, et al. Role of caspases and NF-κB signaling in hydrogen peroxide- and superoxide-induced hepatocyte apoptosis. Am J Physiol 2000;278:G693-G699.
-
(2000)
Am J Physiol
, vol.278
-
-
Jones, B.E.1
Lo, C.R.2
Liu, H.3
Pradhan, Z.4
Garcia, L.5
Srinivasan, A.6
Valentino, K.L.7
-
22
-
-
0032519007
-
NFκB prevents apoptosis and liver dysfunction during liver regeneration
-
Iimuro Y, Nishiura T, Hellerbrand C, Behrns EK, Schoonhoven R, Grisham JW, Brenner DA. NFκB prevents apoptosis and liver dysfunction during liver regeneration. J Clin Invest 1998;101:802-811.
-
(1998)
J Clin Invest
, vol.101
, pp. 802-811
-
-
Iimuro, Y.1
Nishiura, T.2
Hellerbrand, C.3
Behrns, E.K.4
Schoonhoven, R.5
Grisham, J.W.6
Brenner, D.A.7
-
24
-
-
0034704116
-
Inhibition of c-Myc expression sensitizes hepatocytes to tumor necrosis factor-induced apoptosis and necrosis
-
Liu H, Lo CR, Jones BE, Pradhan Z, Srinivasan A, Valentino KL, Stockert RJ, et al. Inhibition of c-Myc expression sensitizes hepatocytes to tumor necrosis factor-induced apoptosis and necrosis. J Biol Chem 2000;275:40155-40162.
-
(2000)
J Biol Chem
, vol.275
, pp. 40155-40162
-
-
Liu, H.1
Lo, C.R.2
Jones, B.E.3
Pradhan, Z.4
Srinivasan, A.5
Valentino, K.L.6
Stockert, R.J.7
-
25
-
-
0028868944
-
Growth inhibition of hepatoma cells induced by vitamin K and its analogs
-
Nishikawa Y, Carr BI, Wang M, Kar S, Finn F, Dowd P, Zheng ZB, et al. Growth inhibition of hepatoma cells induced by vitamin K and its analogs. J Biol Chem 1995;270:28304-28310.
-
(1995)
J Biol Chem
, vol.270
, pp. 28304-28310
-
-
Nishikawa, Y.1
Carr, B.I.2
Wang, M.3
Kar, S.4
Finn, F.5
Dowd, P.6
Zheng, Z.B.7
-
26
-
-
0029166667
-
A synthetic inhibitor of the mitogen-activated protein kinase cascade
-
Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci U S A 1995;92:7686-7689.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7686-7689
-
-
Dudley, D.T.1
Pang, L.2
Decker, S.J.3
Bridges, A.J.4
Saltiel, A.R.5
-
27
-
-
0028884033
-
PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
-
Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 1995;270:27489-27494.
-
(1995)
J Biol Chem
, vol.270
, pp. 27489-27494
-
-
Alessi, D.R.1
Cuenda, A.2
Cohen, P.3
Dudley, D.T.4
Saltiel, A.R.5
-
28
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 2000;351:95-105.
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
29
-
-
0036009411
-
NF-κB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun
-
Liu H, Lo CR, Czaja MJ. NF-κB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun. HEPATOLOGY 2002;35:772-778.
-
(2002)
Hepatology
, vol.35
, pp. 772-778
-
-
Liu, H.1
Lo, C.R.2
Czaja, M.J.3
-
30
-
-
0036086898
-
Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun mediated cell death from TNF-α
-
Liu H, Jones BE, Bradham C, Czaja MJ. Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun mediated cell death from TNF-α. Am J Physiol 2002;282:G257-G266.
-
(2002)
Am J Physiol
, vol.282
-
-
Liu, H.1
Jones, B.E.2
Bradham, C.3
Czaja, M.J.4
-
31
-
-
0034607702
-
Requirement of JNK for stress induced activation of the cytochrome c-mediated death pathway
-
Tournier C, Hess P, Yang DD, Xu J, Turner TK, Nimnual A, Bar-Sagi D, et al. Requirement of JNK for stress induced activation of the cytochrome c-mediated death pathway. Science 2000;288:870-874.
-
(2000)
Science
, vol.288
, pp. 870-874
-
-
Tournier, C.1
Hess, P.2
Yang, D.D.3
Xu, J.4
Turner, T.K.5
Nimnual, A.6
Bar-Sagi, D.7
-
33
-
-
0030886770
-
Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats
-
Aikawa R, Komuro I, Yamazaki T, Zou Y, Kudoh S, Tanaka M, Shiojima I, et al. Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats. J Clin Invest 1997;100:1813-1821.
-
(1997)
J Clin Invest
, vol.100
, pp. 1813-1821
-
-
Aikawa, R.1
Komuro, I.2
Yamazaki, T.3
Zou, Y.4
Kudoh, S.5
Tanaka, M.6
Shiojima, I.7
-
34
-
-
0037172997
-
Ebselen: A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant
-
Zhao R, Masayasu H, Holmgren A. Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant. Proc Natl Acad Sci U S A 2002;99:8579-8584.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 8579-8584
-
-
Zhao, R.1
Masayasu, H.2
Holmgren, A.3
-
35
-
-
0036151709
-
Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes
-
Rao Y-P, Studer EJ, Stravitz RT, Gupta S, Qiao L, Dent P, Hylemon PB. Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes. HEPATOLOGY 2002;35:307-314.
-
(2002)
Hepatology
, vol.35
, pp. 307-314
-
-
Rao, Y.-P.1
Studer, E.J.2
Stravitz, R.T.3
Gupta, S.4
Qiao, L.5
Dent, P.6
Hylemon, P.B.7
-
36
-
-
0036211298
-
Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes
-
Qiao L, Yacoub A, Studer E, Gupta S, Pei XY, Grant S, Hylemon PB, et al. Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes. HEPATOLOGY 2002;35:779-789.
-
(2002)
Hepatology
, vol.35
, pp. 779-789
-
-
Qiao, L.1
Yacoub, A.2
Studer, E.3
Gupta, S.4
Pei, X.Y.5
Grant, S.6
Hylemon, P.B.7
-
37
-
-
0036241214
-
Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner
-
Graf D, Kurz AK, Fischer R, Reinehr R, Häussinger D. Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner. Gastroenterology 2002;122:1411-1427.
-
(2002)
Gastroenterology
, vol.122
, pp. 1411-1427
-
-
Graf, D.1
Kurz, A.K.2
Fischer, R.3
Reinehr, R.4
Häussinger, D.5
-
38
-
-
0032698075
-
Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
-
Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 1999;286:1358-1362.
-
(1999)
Science
, vol.286
, pp. 1358-1362
-
-
Bonni, A.1
Brunet, A.2
West, A.E.3
Datta, S.R.4
Takasu, M.A.5
Greenberg, M.E.6
-
39
-
-
0033970533
-
Dual specificity phosphatases: A gene family for control of MAP kinase function
-
Camps M, Nichols A, Arkinstall S. Dual specificity phosphatases: a gene family for control of MAP kinase function. FASEB J 1999;14:6-16.
-
(1999)
FASEB J
, vol.14
, pp. 6-16
-
-
Camps, M.1
Nichols, A.2
Arkinstall, S.3
-
40
-
-
0033559005
-
Redox-sensitive protein phosphatase activity regulates the phosphorylation state of p38 protein kinase in primary astrocyte culture
-
Robinson KA, Stewart CA, Pye QN, Nguyen X, Kenney L, Salzman S, Floyd RA, et al. Redox-sensitive protein phosphatase activity regulates the phosphorylation state of p38 protein kinase in primary astrocyte culture. J Neurosci Res 1999;55:724-732.
-
(1999)
J Neurosci Res
, vol.55
, pp. 724-732
-
-
Robinson, K.A.1
Stewart, C.A.2
Pye, Q.N.3
Nguyen, X.4
Kenney, L.5
Salzman, S.6
Floyd, R.A.7
-
41
-
-
0034672131
-
Compartment-specific regulation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) mitogen-activated protein kinases (MAPKs) by ERK-dependent and non-ERK-dependent inductions of MAPK phosphatase (MKP)-3 and MKP-1 in differentiating P19 cells
-
Reffas S, Schlegel W. Compartment-specific regulation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) mitogen-activated protein kinases (MAPKs) by ERK-dependent and non-ERK-dependent inductions of MAPK phosphatase (MKP)-3 and MKP-1 in differentiating P19 cells. Biochem J 2000;352:701-708.
-
(2000)
Biochem J
, vol.352
, pp. 701-708
-
-
Reffas, S.1
Schlegel, W.2
-
42
-
-
0031005579
-
Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases
-
Bradham CA, Stachlewitz RF, Gao W, Qian T, Jayadev S, Jenkins G, Hannun Y, et al. Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. HEPATOLOGY 1997;25:1128-1135.
-
(1997)
Hepatology
, vol.25
, pp. 1128-1135
-
-
Bradham, C.A.1
Stachlewitz, R.F.2
Gao, W.3
Qian, T.4
Jayadev, S.5
Jenkins, G.6
Hannun, Y.7
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