메뉴 건너뛰기




Volumn 1, Issue 2, 2005, Pages 101-109

Nanotechnology, nanomedicine, and the development of new, effective therapies for cancer

Author keywords

Cancer therapy; Drug delivery; Nanomedicine; Nanoparticles; Nanotechnology; Quantum dots

Indexed keywords

CANCER THERAPY; DRUG DELIVERY; NANOMEDICINE; NANOPARTICLES;

EID: 33646245291     PISSN: 15499634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nano.2005.03.002     Document Type: Review
Times cited : (344)

References (90)
  • 1
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 409 (2001) 860-921
    • (2001) Nature , vol.409 , pp. 860-921
    • International Human Genome Sequencing Consortium1
  • 3
    • 7244245762 scopus 로고    scopus 로고
    • Finishing the euchromatic sequence of the human genome
    • International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature 431 (2004) 931-945
    • (2004) Nature , vol.431 , pp. 931-945
    • International Human Genome Sequencing Consortium1
  • 4
    • 8444252062 scopus 로고    scopus 로고
    • Laser capture microdissection, microarrays and the precise definition of a cancer cell
    • Player A., Barrett J.C., and Kawasaki E.S. Laser capture microdissection, microarrays and the precise definition of a cancer cell. Expert Rev Mol Diagn 4 (2004) 831-840
    • (2004) Expert Rev Mol Diagn , vol.4 , pp. 831-840
    • Player, A.1    Barrett, J.C.2    Kawasaki, E.S.3
  • 6
    • 0030084093 scopus 로고    scopus 로고
    • Semiconductor clustors, nanocrystals, and quantum dots
    • Alivisatos A.P. Semiconductor clustors, nanocrystals, and quantum dots. Science 271 (1996) 933-937
    • (1996) Science , vol.271 , pp. 933-937
    • Alivisatos, A.P.1
  • 7
    • 0346725932 scopus 로고    scopus 로고
    • The use of nanocrystals in biological detection
    • Alivisatos P. The use of nanocrystals in biological detection. Nat Biotechnol 22 (2004) 47-52
    • (2004) Nat Biotechnol , vol.22 , pp. 47-52
    • Alivisatos, P.1
  • 8
    • 0012392952 scopus 로고    scopus 로고
    • Semiconductor nanocrystals as fluorescent biological labels
    • Bruchez Jr. M., Moronne M., Gin P., Weiss S., and Alivisatos A.P. Semiconductor nanocrystals as fluorescent biological labels. Science 281 (1998) 2013-2016
    • (1998) Science , vol.281 , pp. 2013-2016
    • Bruchez Jr., M.1    Moronne, M.2    Gin, P.3    Weiss, S.4    Alivisatos, A.P.5
  • 9
    • 11144323939 scopus 로고    scopus 로고
    • Quantum dot nanocrystals for in vivo molecular and cellular imaging
    • Smith A.M., Gao X., and Nie S. Quantum dot nanocrystals for in vivo molecular and cellular imaging. Photochem Photobiol 80 (2004) 377-385
    • (2004) Photochem Photobiol , vol.80 , pp. 377-385
    • Smith, A.M.1    Gao, X.2    Nie, S.3
  • 10
    • 11144247257 scopus 로고    scopus 로고
    • Noninvasive MR imaging of magnetically labeled stem cells to directly identify neovasculature in a glioma model
    • Anderson S.A., Glod J., Arbab A.S., Noel M., Ashari P., Fine H.A., et al. Noninvasive MR imaging of magnetically labeled stem cells to directly identify neovasculature in a glioma model. Blood 105 (2005) 420-425
    • (2005) Blood , vol.105 , pp. 420-425
    • Anderson, S.A.1    Glod, J.2    Arbab, A.S.3    Noel, M.4    Ashari, P.5    Fine, H.A.6
  • 11
    • 11044222650 scopus 로고    scopus 로고
    • Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
    • Gupta A.K., and Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials 26 (2005) 3995-4021
    • (2005) Biomaterials , vol.26 , pp. 3995-4021
    • Gupta, A.K.1    Gupta, M.2
  • 12
    • 13844255912 scopus 로고    scopus 로고
    • Sensitive, noninvasive detection of lymph node metastases
    • Harisinghani M.G., and Weissleder R. Sensitive, noninvasive detection of lymph node metastases. Public Libr Sci Med 1 (2004) e66
    • (2004) Public Libr Sci Med , vol.1
    • Harisinghani, M.G.1    Weissleder, R.2
  • 14
    • 4644260094 scopus 로고    scopus 로고
    • Ultrasensitive detection of biomolecules with fluorescent dye-doped nanoparticles
    • Lian W., Litherland S.A., Badrane H., Tan W., Wu D., Baker H.V., et al. Ultrasensitive detection of biomolecules with fluorescent dye-doped nanoparticles. Anal Biochem 334 (2004) 135-144
    • (2004) Anal Biochem , vol.334 , pp. 135-144
    • Lian, W.1    Litherland, S.A.2    Badrane, H.3    Tan, W.4    Wu, D.5    Baker, H.V.6
  • 15
    • 0037225979 scopus 로고    scopus 로고
    • Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots
    • Wu X., Liu H., Liu J., Haley K.N., Treadway J.A., Larson J.P., et al. Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots. Nat Biotechnol 21 (2003) 41-46
    • (2003) Nat Biotechnol , vol.21 , pp. 41-46
    • Wu, X.1    Liu, H.2    Liu, J.3    Haley, K.N.4    Treadway, J.A.5    Larson, J.P.6
  • 16
    • 4344590102 scopus 로고    scopus 로고
    • Chemical analysis and cellular imaging with quantum dots
    • Smith A.M., and Nie S. Chemical analysis and cellular imaging with quantum dots. Analyst 129 (2004) 672-677
    • (2004) Analyst , vol.129 , pp. 672-677
    • Smith, A.M.1    Nie, S.2
  • 18
    • 0348087040 scopus 로고    scopus 로고
    • Long-term multiple color imaging of live cells using quantum dot bioconjugates
    • Jaiswal J.K., Mattoussi H., Mauro J.M., and Simon S.M. Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nat Biotechnol 21 (2003) 47-51
    • (2003) Nat Biotechnol , vol.21 , pp. 47-51
    • Jaiswal, J.K.1    Mattoussi, H.2    Mauro, J.M.3    Simon, S.M.4
  • 20
    • 0034941396 scopus 로고    scopus 로고
    • Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules
    • Han M., Gao X., Su J.Z., and Nie S. Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules. Nat Biotechnol 19 (2001) 631-635
    • (2001) Nat Biotechnol , vol.19 , pp. 631-635
    • Han, M.1    Gao, X.2    Su, J.Z.3    Nie, S.4
  • 22
    • 3543030424 scopus 로고    scopus 로고
    • Zooming in and out with quantum dots
    • Jain R.K., and Stroh M. Zooming in and out with quantum dots. Nat Biotechnol 22 (2004) 959-960
    • (2004) Nat Biotechnol , vol.22 , pp. 959-960
    • Jain, R.K.1    Stroh, M.2
  • 23
    • 8144229655 scopus 로고    scopus 로고
    • Semiconductor quantum dots as contrast agents for whole animal imaging
    • Jiang W., Papa E., Fischer H., Mardyani S., and Chan W.C. Semiconductor quantum dots as contrast agents for whole animal imaging. Trends Biotechnol 22 (2004) 607-609
    • (2004) Trends Biotechnol , vol.22 , pp. 607-609
    • Jiang, W.1    Papa, E.2    Fischer, H.3    Mardyani, S.4    Chan, W.C.5
  • 26
    • 4644237609 scopus 로고    scopus 로고
    • Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy
    • Voura E.B., Jaiswal J.K., Mattoussi H., and Simon S.M. Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy. Nat Med 10 (2004) 993-998
    • (2004) Nat Med , vol.10 , pp. 993-998
    • Voura, E.B.1    Jaiswal, J.K.2    Mattoussi, H.3    Simon, S.M.4
  • 27
    • 0037280208 scopus 로고    scopus 로고
    • Current status of sentinel lymph node mapping and biopsy: facts and controversies
    • Jakub J.W., Pendas S., and Reintgen D.S. Current status of sentinel lymph node mapping and biopsy: facts and controversies. Oncologist 8 (2003) 59-68
    • (2003) Oncologist , vol.8 , pp. 59-68
    • Jakub, J.W.1    Pendas, S.2    Reintgen, D.S.3
  • 28
    • 0347473808 scopus 로고    scopus 로고
    • Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping
    • Kim S., Lim Y.T., Soltesz E.G., De Grand A.M., Lee J., Nakayama A., et al. Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping. Nat Biotechnol 22 (2004) 93-97
    • (2004) Nat Biotechnol , vol.22 , pp. 93-97
    • Kim, S.1    Lim, Y.T.2    Soltesz, E.G.3    De Grand, A.M.4    Lee, J.5    Nakayama, A.6
  • 29
    • 3543022686 scopus 로고    scopus 로고
    • In vivo cancer targeting and imaging with semiconductor quantum dots
    • Gao X., Cui Y., Levenson R.M., Chung L.W., and Nie S. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol 22 (2004) 969-976
    • (2004) Nat Biotechnol , vol.22 , pp. 969-976
    • Gao, X.1    Cui, Y.2    Levenson, R.M.3    Chung, L.W.4    Nie, S.5
  • 31
    • 10044290777 scopus 로고    scopus 로고
    • Development of functionalized superparamagnetic iron oxide nanoparticles for interaction with human cancer cells
    • Petri-Fink A., Chastellain M., Juillerat-Jeanneret L., Ferrari A., and Hofmann H. Development of functionalized superparamagnetic iron oxide nanoparticles for interaction with human cancer cells. Biomaterials 26 (2005) 2685-2694
    • (2005) Biomaterials , vol.26 , pp. 2685-2694
    • Petri-Fink, A.1    Chastellain, M.2    Juillerat-Jeanneret, L.3    Ferrari, A.4    Hofmann, H.5
  • 32
    • 20044383193 scopus 로고    scopus 로고
    • Workshop on cancer biometrics. Identifying biomarkers and surrogates of cancer in patients: a meeting held at the Masur Auditorium, National Institutes of Health
    • Lotze M.T., Wang E., Marincola F.M., Hanna N., Bugelski P.J., Burns C.A., et al. Workshop on cancer biometrics. Identifying biomarkers and surrogates of cancer in patients: a meeting held at the Masur Auditorium, National Institutes of Health. J Immunother 28 (2005) 79-119
    • (2005) J Immunother , vol.28 , pp. 79-119
    • Lotze, M.T.1    Wang, E.2    Marincola, F.M.3    Hanna, N.4    Bugelski, P.J.5    Burns, C.A.6
  • 33
    • 12344289403 scopus 로고    scopus 로고
    • Proteomic analysis for the early detection and rational treatment of cancer-realistic hope?
    • Posadas E.M., Simpkins F., Liotta L.A., MacDonald C., and Kohn E.C. Proteomic analysis for the early detection and rational treatment of cancer-realistic hope?. Ann Oncol 16 (2005) 16-22
    • (2005) Ann Oncol , vol.16 , pp. 16-22
    • Posadas, E.M.1    Simpkins, F.2    Liotta, L.A.3    MacDonald, C.4    Kohn, E.C.5
  • 34
    • 14044279957 scopus 로고    scopus 로고
    • Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease
    • Georganopoulou D.G., Chang L., Nam J.M., Thaxton C.S., Mufson E.J., Klein W.L., et al. Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease. Proc Natl Acad Sci U S A 102 (2005) 2273-2276
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2273-2276
    • Georganopoulou, D.G.1    Chang, L.2    Nam, J.M.3    Thaxton, C.S.4    Mufson, E.J.5    Klein, W.L.6
  • 35
    • 14044255959 scopus 로고    scopus 로고
    • Nanoscience enables ultrasensitive detection of Alzheimer's biomarker
    • Keating C.D. Nanoscience enables ultrasensitive detection of Alzheimer's biomarker. Proc Natl Acad Sci U S A 102 (2005) 2263-2264
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2263-2264
    • Keating, C.D.1
  • 36
    • 0141868926 scopus 로고    scopus 로고
    • Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins
    • Nam J.M., Thaxton C.S., and Mirkin C.A. Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins. Science 301 (2003) 1884-1886
    • (2003) Science , vol.301 , pp. 1884-1886
    • Nam, J.M.1    Thaxton, C.S.2    Mirkin, C.A.3
  • 37
    • 0242653640 scopus 로고    scopus 로고
    • Clinical proteomics: written in blood
    • Liotta L.A., Ferrari M., and Petricoin E. Clinical proteomics: written in blood. Nature 425 (2003) 905
    • (2003) Nature , vol.425 , pp. 905
    • Liotta, L.A.1    Ferrari, M.2    Petricoin, E.3
  • 38
    • 0346848865 scopus 로고    scopus 로고
    • Nanotech approaches to drug delivery and imaging
    • Sahoo S.K., and Labhasetwar V. Nanotech approaches to drug delivery and imaging. Drug Discov Today 8 (2003) 1112-1120
    • (2003) Drug Discov Today , vol.8 , pp. 1112-1120
    • Sahoo, S.K.1    Labhasetwar, V.2
  • 39
    • 24144450963 scopus 로고    scopus 로고
    • Nanosystems in drug targeting: opportunities and challenges
    • Vasir J.K., Reddy M.K., and Labhasetwar V. Nanosystems in drug targeting: opportunities and challenges. Curr Nanosci 1 (2005) 47-64
    • (2005) Curr Nanosci , vol.1 , pp. 47-64
    • Vasir, J.K.1    Reddy, M.K.2    Labhasetwar, V.3
  • 40
    • 5344234787 scopus 로고    scopus 로고
    • The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs
    • Kipp J.E. The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs. Int J Pharm 284 (2004) 109-122
    • (2004) Int J Pharm , vol.284 , pp. 109-122
    • Kipp, J.E.1
  • 41
    • 4544275025 scopus 로고    scopus 로고
    • Challenges and solutions for the delivery of biotech drugs-a review of drug nanocrystal technology and lipid nanoparticles
    • Muller R.H., and Keck C.M. Challenges and solutions for the delivery of biotech drugs-a review of drug nanocrystal technology and lipid nanoparticles. J Biotechnol 113 (2004) 151-170
    • (2004) J Biotechnol , vol.113 , pp. 151-170
    • Muller, R.H.1    Keck, C.M.2
  • 42
    • 4544383493 scopus 로고    scopus 로고
    • Nanosuspensions in drug delivery
    • Rabinow B.E. Nanosuspensions in drug delivery. Nat Rev Drug Discov 3 (2004) 785-796
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 785-796
    • Rabinow, B.E.1
  • 43
    • 0035803697 scopus 로고    scopus 로고
    • Organic nanoparticles in the aqueous phase-theory, experiment, and use
    • Horn D., and Rieger J. Organic nanoparticles in the aqueous phase-theory, experiment, and use. Angew Chem Int Ed 40 (2001) 4330-4361
    • (2001) Angew Chem Int Ed , vol.40 , pp. 4330-4361
    • Horn, D.1    Rieger, J.2
  • 44
    • 14144250911 scopus 로고    scopus 로고
    • Recent advances with liposomes as pharmaceutical carriers
    • Torchilin V.P. Recent advances with liposomes as pharmaceutical carriers. Nat Rev Drug Discov 4 (2005) 145-160
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 145-160
    • Torchilin, V.P.1
  • 45
    • 1942453805 scopus 로고    scopus 로고
    • Solid lipid nanoparticles for parenteral drug delivery
    • Wissing S.A., Kayser O., and Muller R.H. Solid lipid nanoparticles for parenteral drug delivery. Adv Drug Deliv Rev 56 (2004) 1257-1272
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 1257-1272
    • Wissing, S.A.1    Kayser, O.2    Muller, R.H.3
  • 46
    • 4544240398 scopus 로고    scopus 로고
    • Paclitaxel nanoparticles for the potential treatment of brain tumors
    • Koziara J.M., Lockman P.R., Allen D.D., and Mumper R.J. Paclitaxel nanoparticles for the potential treatment of brain tumors. J Control Release 99 (2004) 259-269
    • (2004) J Control Release , vol.99 , pp. 259-269
    • Koziara, J.M.1    Lockman, P.R.2    Allen, D.D.3    Mumper, R.J.4
  • 48
    • 4444379133 scopus 로고    scopus 로고
    • Nanoparticle and targeted systems for cancer therapy
    • Brannon-Peppas L., and Blanchette J.O. Nanoparticle and targeted systems for cancer therapy. Adv Drug Deliv Rev 56 (2004) 1649-1659
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 1649-1659
    • Brannon-Peppas, L.1    Blanchette, J.O.2
  • 50
    • 17144433510 scopus 로고    scopus 로고
    • Enhanced transfection efficiency of a systemically delivered tumor-targeting immunolipoplex by inclusion of a pH-sensitive histidylated oligolysine peptide
    • Yu W., Pirollo K.F., Yu B., Rait A., Xiang L., Huang W., et al. Enhanced transfection efficiency of a systemically delivered tumor-targeting immunolipoplex by inclusion of a pH-sensitive histidylated oligolysine peptide. Nucleic Acids Res 32 (2004) e48
    • (2004) Nucleic Acids Res , vol.32
    • Yu, W.1    Pirollo, K.F.2    Yu, B.3    Rait, A.4    Xiang, L.5    Huang, W.6
  • 51
    • 7444223607 scopus 로고    scopus 로고
    • Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells
    • Farokhzad O.C., Jon S., Khademhosseini A., Tran T.N., Lavan D.A., and Langer R. Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer Res 64 (2004) 7668-7672
    • (2004) Cancer Res , vol.64 , pp. 7668-7672
    • Farokhzad, O.C.1    Jon, S.2    Khademhosseini, A.3    Tran, T.N.4    Lavan, D.A.5    Langer, R.6
  • 53
    • 12844258906 scopus 로고    scopus 로고
    • Dendrimers and dendritic polymers in drug delivery
    • Gillies E.R., and Frechet J.M. Dendrimers and dendritic polymers in drug delivery. Drug Discov Today 10 (2005) 35-43
    • (2005) Drug Discov Today , vol.10 , pp. 35-43
    • Gillies, E.R.1    Frechet, J.M.2
  • 54
    • 14544298301 scopus 로고    scopus 로고
    • Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
    • Schiffelers R.M., Ansari A., Xu J., Zhou Q., Tang Q., Storm G., et al. Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res 32 (2004) e149
    • (2004) Nucleic Acids Res , vol.32
    • Schiffelers, R.M.1    Ansari, A.2    Xu, J.3    Zhou, Q.4    Tang, Q.5    Storm, G.6
  • 55
    • 0141765891 scopus 로고    scopus 로고
    • The "right" size in nanobiotechnology
    • Whitesides G.M. The "right" size in nanobiotechnology. Nat Biotechnol 21 (2003) 1161-1165
    • (2003) Nat Biotechnol , vol.21 , pp. 1161-1165
    • Whitesides, G.M.1
  • 56
    • 19744382195 scopus 로고    scopus 로고
    • Electronic structure and bonding of Au on a SiO2 cluster: a nanobullet for tumors
    • Sun Q., Wang Q., Rao B.K., and Jena P. Electronic structure and bonding of Au on a SiO2 cluster: a nanobullet for tumors. Phys Rev Lett 93 (2004) 186803/1-186803/4
    • (2004) Phys Rev Lett , vol.93
    • Sun, Q.1    Wang, Q.2    Rao, B.K.3    Jena, P.4
  • 57
    • 7444253428 scopus 로고    scopus 로고
    • Systems biology and new technologies enable predictive and preventative medicine
    • Hood L., Heath J.R., Phelps M.E., and Lin B. Systems biology and new technologies enable predictive and preventative medicine. Science 306 (2004) 640-643
    • (2004) Science , vol.306 , pp. 640-643
    • Hood, L.1    Heath, J.R.2    Phelps, M.E.3    Lin, B.4
  • 58
    • 5044229321 scopus 로고    scopus 로고
    • The impact of systems approaches on biological problems in drug discovery
    • Hood L., and Perlmutter R.M. The impact of systems approaches on biological problems in drug discovery. Nat Biotechnol 22 (2004) 1215-1217
    • (2004) Nat Biotechnol , vol.22 , pp. 1215-1217
    • Hood, L.1    Perlmutter, R.M.2
  • 59
    • 14044261316 scopus 로고    scopus 로고
    • Opinion: what's wrong with our cancer models?
    • Kamb A. Opinion: what's wrong with our cancer models?. Nat Rev Drug Discov 4 (2005) 161-165
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 161-165
    • Kamb, A.1
  • 60
    • 2442621619 scopus 로고    scopus 로고
    • Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
    • Ferrara N., Hillan K.J., Gerber H.P., and Novotny W. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov 3 (2004) 391-400
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 391-400
    • Ferrara, N.1    Hillan, K.J.2    Gerber, H.P.3    Novotny, W.4
  • 62
    • 4944242884 scopus 로고    scopus 로고
    • A vision for the National Cancer Program in the United States
    • von Eschenbach A.C. A vision for the National Cancer Program in the United States. Nat Rev Cancer 4 (2004) 820-828
    • (2004) Nat Rev Cancer , vol.4 , pp. 820-828
    • von Eschenbach, A.C.1
  • 63
    • 3142781225 scopus 로고    scopus 로고
    • Small-molecule inhibitors of protein-protein interactions: progressing towards the dream
    • Arkin M.R., and Wells J.A. Small-molecule inhibitors of protein-protein interactions: progressing towards the dream. Nat Rev Drug Discov 3 (2004) 301-317
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 301-317
    • Arkin, M.R.1    Wells, J.A.2
  • 65
    • 20844437061 scopus 로고    scopus 로고
    • A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design
    • Card G.L., Blasdel L., England B.P., Zhang C., Suzuki Y., Gillette S., et al. A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design. Nat Biotechnol 23 (2005) 201-207
    • (2005) Nat Biotechnol , vol.23 , pp. 201-207
    • Card, G.L.1    Blasdel, L.2    England, B.P.3    Zhang, C.4    Suzuki, Y.5    Gillette, S.6
  • 67
    • 11144320699 scopus 로고    scopus 로고
    • Navigating chemical space for biology and medicine
    • Lipinski C., and Hopkins A. Navigating chemical space for biology and medicine. Nature 432 (2004) 855-861
    • (2004) Nature , vol.432 , pp. 855-861
    • Lipinski, C.1    Hopkins, A.2
  • 69
    • 11144323163 scopus 로고    scopus 로고
    • Virtual screening of chemical libraries
    • Shoichet B.K. Virtual screening of chemical libraries. Nature 432 (2004) 862-865
    • (2004) Nature , vol.432 , pp. 862-865
    • Shoichet, B.K.1
  • 70
    • 0036635291 scopus 로고    scopus 로고
    • Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug
    • Capdeville R., Buchdunger E., Zimmermann J., and Matter A. Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug. Nat Rev Drug Discov 1 (2002) 493-502
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 493-502
    • Capdeville, R.1    Buchdunger, E.2    Zimmermann, J.3    Matter, A.4
  • 71
    • 4344623889 scopus 로고    scopus 로고
    • Imatinib as a paradigm of targeted therapies
    • Druker B.J. Imatinib as a paradigm of targeted therapies. Adv Cancer Res 91 (2004) 1-30
    • (2004) Adv Cancer Res , vol.91 , pp. 1-30
    • Druker, B.J.1
  • 72
    • 14744274624 scopus 로고    scopus 로고
    • Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance
    • Burgess M.R., Skaggs B.J., Shah N.P., Lee F.Y., and Sawyers C.L. Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance. Proc Natl Acad Sci U S A (2005)
    • (2005) Proc Natl Acad Sci U S A
    • Burgess, M.R.1    Skaggs, B.J.2    Shah, N.P.3    Lee, F.Y.4    Sawyers, C.L.5
  • 74
    • 3142676436 scopus 로고    scopus 로고
    • Overriding imatinib resistance with a novel ABL kinase inhibitor
    • Shah N.P., Tran C., Lee F.Y., Chen P., Norris D., and Sawyers C.L. Overriding imatinib resistance with a novel ABL kinase inhibitor. Science 305 (2004) 399-401
    • (2004) Science , vol.305 , pp. 399-401
    • Shah, N.P.1    Tran, C.2    Lee, F.Y.3    Chen, P.4    Norris, D.5    Sawyers, C.L.6
  • 75
    • 3242719541 scopus 로고    scopus 로고
    • Antisense strategies
    • Crooke S.T. Antisense strategies. Curr Mol Med 4 (2004) 465-487
    • (2004) Curr Mol Med , vol.4 , pp. 465-487
    • Crooke, S.T.1
  • 76
    • 12344303295 scopus 로고    scopus 로고
    • Antisense oligonucleotides targeted to the human alpha folate receptor inhibit breast cancer cell growth and sensitize the cells to doxorubicin treatment
    • Jhaveri M.S., Rait A.S., Chung K.N., Trepel J.B., and Chang E.H. Antisense oligonucleotides targeted to the human alpha folate receptor inhibit breast cancer cell growth and sensitize the cells to doxorubicin treatment. Mol Cancer Ther 3 (2004) 1505-1512
    • (2004) Mol Cancer Ther , vol.3 , pp. 1505-1512
    • Jhaveri, M.S.1    Rait, A.S.2    Chung, K.N.3    Trepel, J.B.4    Chang, E.H.5
  • 77
    • 3242677639 scopus 로고    scopus 로고
    • siRNAs: applications in functional genomics and potential as therapeutics
    • Dorsett Y., and Tuschl T. siRNAs: applications in functional genomics and potential as therapeutics. Nat Rev Drug Discov 3 (2004) 318-329
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 318-329
    • Dorsett, Y.1    Tuschl, T.2
  • 78
    • 9144260199 scopus 로고    scopus 로고
    • Use of RNA interference libraries to investigate oncogenic signalling in mammalian cells
    • Downward J. Use of RNA interference libraries to investigate oncogenic signalling in mammalian cells. Oncogene 23 (2004) 8376-8383
    • (2004) Oncogene , vol.23 , pp. 8376-8383
    • Downward, J.1
  • 79
    • 3242656346 scopus 로고    scopus 로고
    • Silencing of disease-related genes by small interfering RNAs
    • Fuchs U., Damm-Welk C., and Borkhardt A. Silencing of disease-related genes by small interfering RNAs. Curr Mol Med 4 (2004) 507-517
    • (2004) Curr Mol Med , vol.4 , pp. 507-517
    • Fuchs, U.1    Damm-Welk, C.2    Borkhardt, A.3
  • 80
    • 2342537869 scopus 로고    scopus 로고
    • The promise of cancer vaccines
    • Gilboa E. The promise of cancer vaccines. Nat Rev Cancer 4 (2004) 401-411
    • (2004) Nat Rev Cancer , vol.4 , pp. 401-411
    • Gilboa, E.1
  • 81
    • 0042470540 scopus 로고    scopus 로고
    • Does the immune system see tumors as foreign or self?
    • Pardoll D. Does the immune system see tumors as foreign or self?. Annu Rev Immunol 21 (2003) 807-839
    • (2003) Annu Rev Immunol , vol.21 , pp. 807-839
    • Pardoll, D.1
  • 82
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: moving beyond current vaccines
    • Rosenberg S.A., Yang J.C., and Restifo N.P. Cancer immunotherapy: moving beyond current vaccines. Nat Med 10 (2004) 909-915
    • (2004) Nat Med , vol.10 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 83
    • 4344697146 scopus 로고    scopus 로고
    • Size-dependent immunogenicity: therapeutic and protective properties of nano-vaccines against tumors
    • Fifis T., Gamvrellis A., Crimeen-Irwin B., Pietersz G.A., Li J., Mottram P.L., et al. Size-dependent immunogenicity: therapeutic and protective properties of nano-vaccines against tumors. J Immunol 173 (2004) 3148-3154
    • (2004) J Immunol , vol.173 , pp. 3148-3154
    • Fifis, T.1    Gamvrellis, A.2    Crimeen-Irwin, B.3    Pietersz, G.A.4    Li, J.5    Mottram, P.L.6
  • 84
    • 8644225816 scopus 로고    scopus 로고
    • Introduction: thermal ablation therapy
    • Stauffer P.R., and Goldberg S.N. Introduction: thermal ablation therapy. Int J Hyperthermia 20 (2004) 671-677
    • (2004) Int J Hyperthermia , vol.20 , pp. 671-677
    • Stauffer, P.R.1    Goldberg, S.N.2
  • 85
    • 0038182397 scopus 로고    scopus 로고
    • Nanoscale photonics: nanoshells: gifts in a gold wrapper
    • Brongersma M.L. Nanoscale photonics: nanoshells: gifts in a gold wrapper. Nat Mater 2 (2003) 296-297
    • (2003) Nat Mater , vol.2 , pp. 296-297
    • Brongersma, M.L.1
  • 87
    • 2442692534 scopus 로고    scopus 로고
    • Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles
    • O'Neal D.P., Hirsch L.R., Halas N.J., Payne J.D., and West J.L. Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles. Cancer Lett 209 (2004) 171-176
    • (2004) Cancer Lett , vol.209 , pp. 171-176
    • O'Neal, D.P.1    Hirsch, L.R.2    Halas, N.J.3    Payne, J.D.4    West, J.L.5
  • 88
    • 16644382078 scopus 로고    scopus 로고
    • US NCI launches nanotechnology plan
    • Alper J. US NCI launches nanotechnology plan. Nat Biotechnol 22 (2004) 1335-1336
    • (2004) Nat Biotechnol , vol.22 , pp. 1335-1336
    • Alper, J.1
  • 90
    • 23644433384 scopus 로고    scopus 로고
    • How cancer could be cured by 2015
    • Blagosklonny M.V. How cancer could be cured by 2015. Cell Cycle 4 (2005)
    • (2005) Cell Cycle , vol.4
    • Blagosklonny, M.V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.