-
1
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 409 (2001) 860-921
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
International Human Genome Sequencing Consortium1
-
2
-
-
0035895505
-
The sequence of the human genome
-
Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., et al. The sequence of the human genome. Science 291 (2001) 1304-1351
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
-
3
-
-
7244245762
-
Finishing the euchromatic sequence of the human genome
-
International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature 431 (2004) 931-945
-
(2004)
Nature
, vol.431
, pp. 931-945
-
-
International Human Genome Sequencing Consortium1
-
4
-
-
8444252062
-
Laser capture microdissection, microarrays and the precise definition of a cancer cell
-
Player A., Barrett J.C., and Kawasaki E.S. Laser capture microdissection, microarrays and the precise definition of a cancer cell. Expert Rev Mol Diagn 4 (2004) 831-840
-
(2004)
Expert Rev Mol Diagn
, vol.4
, pp. 831-840
-
-
Player, A.1
Barrett, J.C.2
Kawasaki, E.S.3
-
5
-
-
13144268599
-
To be nano or not to be nano?
-
Joachim C., Emerich D.F., Wu X., Liu H., Liu J., Haley K.N., et al. To be nano or not to be nano?. Nat Mater 4 (2005) 107-109
-
(2005)
Nat Mater
, vol.4
, pp. 107-109
-
-
Joachim, C.1
Emerich, D.F.2
Wu, X.3
Liu, H.4
Liu, J.5
Haley, K.N.6
-
6
-
-
0030084093
-
Semiconductor clustors, nanocrystals, and quantum dots
-
Alivisatos A.P. Semiconductor clustors, nanocrystals, and quantum dots. Science 271 (1996) 933-937
-
(1996)
Science
, vol.271
, pp. 933-937
-
-
Alivisatos, A.P.1
-
7
-
-
0346725932
-
The use of nanocrystals in biological detection
-
Alivisatos P. The use of nanocrystals in biological detection. Nat Biotechnol 22 (2004) 47-52
-
(2004)
Nat Biotechnol
, vol.22
, pp. 47-52
-
-
Alivisatos, P.1
-
8
-
-
0012392952
-
Semiconductor nanocrystals as fluorescent biological labels
-
Bruchez Jr. M., Moronne M., Gin P., Weiss S., and Alivisatos A.P. Semiconductor nanocrystals as fluorescent biological labels. Science 281 (1998) 2013-2016
-
(1998)
Science
, vol.281
, pp. 2013-2016
-
-
Bruchez Jr., M.1
Moronne, M.2
Gin, P.3
Weiss, S.4
Alivisatos, A.P.5
-
9
-
-
11144323939
-
Quantum dot nanocrystals for in vivo molecular and cellular imaging
-
Smith A.M., Gao X., and Nie S. Quantum dot nanocrystals for in vivo molecular and cellular imaging. Photochem Photobiol 80 (2004) 377-385
-
(2004)
Photochem Photobiol
, vol.80
, pp. 377-385
-
-
Smith, A.M.1
Gao, X.2
Nie, S.3
-
10
-
-
11144247257
-
Noninvasive MR imaging of magnetically labeled stem cells to directly identify neovasculature in a glioma model
-
Anderson S.A., Glod J., Arbab A.S., Noel M., Ashari P., Fine H.A., et al. Noninvasive MR imaging of magnetically labeled stem cells to directly identify neovasculature in a glioma model. Blood 105 (2005) 420-425
-
(2005)
Blood
, vol.105
, pp. 420-425
-
-
Anderson, S.A.1
Glod, J.2
Arbab, A.S.3
Noel, M.4
Ashari, P.5
Fine, H.A.6
-
11
-
-
11044222650
-
Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
-
Gupta A.K., and Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials 26 (2005) 3995-4021
-
(2005)
Biomaterials
, vol.26
, pp. 3995-4021
-
-
Gupta, A.K.1
Gupta, M.2
-
12
-
-
13844255912
-
Sensitive, noninvasive detection of lymph node metastases
-
Harisinghani M.G., and Weissleder R. Sensitive, noninvasive detection of lymph node metastases. Public Libr Sci Med 1 (2004) e66
-
(2004)
Public Libr Sci Med
, vol.1
-
-
Harisinghani, M.G.1
Weissleder, R.2
-
13
-
-
3843136221
-
New magnetic nanoparticles for biotechnology
-
Hutten A., Sudfeld D., Ennen I., Reiss G., Hachmann W., Heinzmann U., et al. New magnetic nanoparticles for biotechnology. J Biotechnol 112 (2004) 47-63
-
(2004)
J Biotechnol
, vol.112
, pp. 47-63
-
-
Hutten, A.1
Sudfeld, D.2
Ennen, I.3
Reiss, G.4
Hachmann, W.5
Heinzmann, U.6
-
14
-
-
4644260094
-
Ultrasensitive detection of biomolecules with fluorescent dye-doped nanoparticles
-
Lian W., Litherland S.A., Badrane H., Tan W., Wu D., Baker H.V., et al. Ultrasensitive detection of biomolecules with fluorescent dye-doped nanoparticles. Anal Biochem 334 (2004) 135-144
-
(2004)
Anal Biochem
, vol.334
, pp. 135-144
-
-
Lian, W.1
Litherland, S.A.2
Badrane, H.3
Tan, W.4
Wu, D.5
Baker, H.V.6
-
15
-
-
0037225979
-
Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots
-
Wu X., Liu H., Liu J., Haley K.N., Treadway J.A., Larson J.P., et al. Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots. Nat Biotechnol 21 (2003) 41-46
-
(2003)
Nat Biotechnol
, vol.21
, pp. 41-46
-
-
Wu, X.1
Liu, H.2
Liu, J.3
Haley, K.N.4
Treadway, J.A.5
Larson, J.P.6
-
16
-
-
4344590102
-
Chemical analysis and cellular imaging with quantum dots
-
Smith A.M., and Nie S. Chemical analysis and cellular imaging with quantum dots. Analyst 129 (2004) 672-677
-
(2004)
Analyst
, vol.129
, pp. 672-677
-
-
Smith, A.M.1
Nie, S.2
-
18
-
-
0348087040
-
Long-term multiple color imaging of live cells using quantum dot bioconjugates
-
Jaiswal J.K., Mattoussi H., Mauro J.M., and Simon S.M. Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nat Biotechnol 21 (2003) 47-51
-
(2003)
Nat Biotechnol
, vol.21
, pp. 47-51
-
-
Jaiswal, J.K.1
Mattoussi, H.2
Mauro, J.M.3
Simon, S.M.4
-
19
-
-
19944433260
-
Quantum dots for live cells, in vivo imaging, and diagnostics
-
Michalet X., Pinaud F.F., Bentolila L.A., Tsay J.M., Doose S., Li J.J., et al. Quantum dots for live cells, in vivo imaging, and diagnostics. Science 307 (2005) 538-544
-
(2005)
Science
, vol.307
, pp. 538-544
-
-
Michalet, X.1
Pinaud, F.F.2
Bentolila, L.A.3
Tsay, J.M.4
Doose, S.5
Li, J.J.6
-
20
-
-
0034941396
-
Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules
-
Han M., Gao X., Su J.Z., and Nie S. Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules. Nat Biotechnol 19 (2001) 631-635
-
(2001)
Nat Biotechnol
, vol.19
, pp. 631-635
-
-
Han, M.1
Gao, X.2
Su, J.Z.3
Nie, S.4
-
21
-
-
1642503058
-
Optical coding of mammalian cells using semiconductor quantum dots
-
Mattheakis L.C., Dias J.M., Choi Y.J., Gong J., Bruchez M.P., Liu J., et al. Optical coding of mammalian cells using semiconductor quantum dots. Anal Biochem 327 (2004) 200-208
-
(2004)
Anal Biochem
, vol.327
, pp. 200-208
-
-
Mattheakis, L.C.1
Dias, J.M.2
Choi, Y.J.3
Gong, J.4
Bruchez, M.P.5
Liu, J.6
-
22
-
-
3543030424
-
Zooming in and out with quantum dots
-
Jain R.K., and Stroh M. Zooming in and out with quantum dots. Nat Biotechnol 22 (2004) 959-960
-
(2004)
Nat Biotechnol
, vol.22
, pp. 959-960
-
-
Jain, R.K.1
Stroh, M.2
-
23
-
-
8144229655
-
Semiconductor quantum dots as contrast agents for whole animal imaging
-
Jiang W., Papa E., Fischer H., Mardyani S., and Chan W.C. Semiconductor quantum dots as contrast agents for whole animal imaging. Trends Biotechnol 22 (2004) 607-609
-
(2004)
Trends Biotechnol
, vol.22
, pp. 607-609
-
-
Jiang, W.1
Papa, E.2
Fischer, H.3
Mardyani, S.4
Chan, W.C.5
-
24
-
-
0038780625
-
Water-soluble quantum dots for multiphoton fluorescence imaging in vivo
-
Larson D.R., Zipfel W.R., Williams R.M., Clark S.W., Bruchez M.P., Wise F.W., et al. Water-soluble quantum dots for multiphoton fluorescence imaging in vivo. Science 300 (2003) 1434-1436
-
(2003)
Science
, vol.300
, pp. 1434-1436
-
-
Larson, D.R.1
Zipfel, W.R.2
Williams, R.M.3
Clark, S.W.4
Bruchez, M.P.5
Wise, F.W.6
-
25
-
-
0036792082
-
Nanocrystal targeting in vivo
-
Akerman M.E., Chan W.C., Laakkonen P., Bhatia S.N., and Ruoslahti E. Nanocrystal targeting in vivo. Proc Natl Acad Sci U S A 99 (2002) 12617-12621
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 12617-12621
-
-
Akerman, M.E.1
Chan, W.C.2
Laakkonen, P.3
Bhatia, S.N.4
Ruoslahti, E.5
-
26
-
-
4644237609
-
Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy
-
Voura E.B., Jaiswal J.K., Mattoussi H., and Simon S.M. Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy. Nat Med 10 (2004) 993-998
-
(2004)
Nat Med
, vol.10
, pp. 993-998
-
-
Voura, E.B.1
Jaiswal, J.K.2
Mattoussi, H.3
Simon, S.M.4
-
27
-
-
0037280208
-
Current status of sentinel lymph node mapping and biopsy: facts and controversies
-
Jakub J.W., Pendas S., and Reintgen D.S. Current status of sentinel lymph node mapping and biopsy: facts and controversies. Oncologist 8 (2003) 59-68
-
(2003)
Oncologist
, vol.8
, pp. 59-68
-
-
Jakub, J.W.1
Pendas, S.2
Reintgen, D.S.3
-
28
-
-
0347473808
-
Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping
-
Kim S., Lim Y.T., Soltesz E.G., De Grand A.M., Lee J., Nakayama A., et al. Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping. Nat Biotechnol 22 (2004) 93-97
-
(2004)
Nat Biotechnol
, vol.22
, pp. 93-97
-
-
Kim, S.1
Lim, Y.T.2
Soltesz, E.G.3
De Grand, A.M.4
Lee, J.5
Nakayama, A.6
-
29
-
-
3543022686
-
In vivo cancer targeting and imaging with semiconductor quantum dots
-
Gao X., Cui Y., Levenson R.M., Chung L.W., and Nie S. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol 22 (2004) 969-976
-
(2004)
Nat Biotechnol
, vol.22
, pp. 969-976
-
-
Gao, X.1
Cui, Y.2
Levenson, R.M.3
Chung, L.W.4
Nie, S.5
-
30
-
-
14544298820
-
Near-infrared-emissive polymersomes: self-assembled soft matter for in vivo optical imaging
-
Ghoroghchian P.P., Frail P.R., Susumu K., Blessington D., Brannan A.K., Bates F.S., et al. Near-infrared-emissive polymersomes: self-assembled soft matter for in vivo optical imaging. Proc Natl Acad Sci U S A 102 (2005) 2922-2927
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 2922-2927
-
-
Ghoroghchian, P.P.1
Frail, P.R.2
Susumu, K.3
Blessington, D.4
Brannan, A.K.5
Bates, F.S.6
-
31
-
-
10044290777
-
Development of functionalized superparamagnetic iron oxide nanoparticles for interaction with human cancer cells
-
Petri-Fink A., Chastellain M., Juillerat-Jeanneret L., Ferrari A., and Hofmann H. Development of functionalized superparamagnetic iron oxide nanoparticles for interaction with human cancer cells. Biomaterials 26 (2005) 2685-2694
-
(2005)
Biomaterials
, vol.26
, pp. 2685-2694
-
-
Petri-Fink, A.1
Chastellain, M.2
Juillerat-Jeanneret, L.3
Ferrari, A.4
Hofmann, H.5
-
32
-
-
20044383193
-
Workshop on cancer biometrics. Identifying biomarkers and surrogates of cancer in patients: a meeting held at the Masur Auditorium, National Institutes of Health
-
Lotze M.T., Wang E., Marincola F.M., Hanna N., Bugelski P.J., Burns C.A., et al. Workshop on cancer biometrics. Identifying biomarkers and surrogates of cancer in patients: a meeting held at the Masur Auditorium, National Institutes of Health. J Immunother 28 (2005) 79-119
-
(2005)
J Immunother
, vol.28
, pp. 79-119
-
-
Lotze, M.T.1
Wang, E.2
Marincola, F.M.3
Hanna, N.4
Bugelski, P.J.5
Burns, C.A.6
-
33
-
-
12344289403
-
Proteomic analysis for the early detection and rational treatment of cancer-realistic hope?
-
Posadas E.M., Simpkins F., Liotta L.A., MacDonald C., and Kohn E.C. Proteomic analysis for the early detection and rational treatment of cancer-realistic hope?. Ann Oncol 16 (2005) 16-22
-
(2005)
Ann Oncol
, vol.16
, pp. 16-22
-
-
Posadas, E.M.1
Simpkins, F.2
Liotta, L.A.3
MacDonald, C.4
Kohn, E.C.5
-
34
-
-
14044279957
-
Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease
-
Georganopoulou D.G., Chang L., Nam J.M., Thaxton C.S., Mufson E.J., Klein W.L., et al. Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease. Proc Natl Acad Sci U S A 102 (2005) 2273-2276
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 2273-2276
-
-
Georganopoulou, D.G.1
Chang, L.2
Nam, J.M.3
Thaxton, C.S.4
Mufson, E.J.5
Klein, W.L.6
-
35
-
-
14044255959
-
Nanoscience enables ultrasensitive detection of Alzheimer's biomarker
-
Keating C.D. Nanoscience enables ultrasensitive detection of Alzheimer's biomarker. Proc Natl Acad Sci U S A 102 (2005) 2263-2264
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 2263-2264
-
-
Keating, C.D.1
-
36
-
-
0141868926
-
Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins
-
Nam J.M., Thaxton C.S., and Mirkin C.A. Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins. Science 301 (2003) 1884-1886
-
(2003)
Science
, vol.301
, pp. 1884-1886
-
-
Nam, J.M.1
Thaxton, C.S.2
Mirkin, C.A.3
-
37
-
-
0242653640
-
Clinical proteomics: written in blood
-
Liotta L.A., Ferrari M., and Petricoin E. Clinical proteomics: written in blood. Nature 425 (2003) 905
-
(2003)
Nature
, vol.425
, pp. 905
-
-
Liotta, L.A.1
Ferrari, M.2
Petricoin, E.3
-
38
-
-
0346848865
-
Nanotech approaches to drug delivery and imaging
-
Sahoo S.K., and Labhasetwar V. Nanotech approaches to drug delivery and imaging. Drug Discov Today 8 (2003) 1112-1120
-
(2003)
Drug Discov Today
, vol.8
, pp. 1112-1120
-
-
Sahoo, S.K.1
Labhasetwar, V.2
-
39
-
-
24144450963
-
Nanosystems in drug targeting: opportunities and challenges
-
Vasir J.K., Reddy M.K., and Labhasetwar V. Nanosystems in drug targeting: opportunities and challenges. Curr Nanosci 1 (2005) 47-64
-
(2005)
Curr Nanosci
, vol.1
, pp. 47-64
-
-
Vasir, J.K.1
Reddy, M.K.2
Labhasetwar, V.3
-
40
-
-
5344234787
-
The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs
-
Kipp J.E. The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs. Int J Pharm 284 (2004) 109-122
-
(2004)
Int J Pharm
, vol.284
, pp. 109-122
-
-
Kipp, J.E.1
-
41
-
-
4544275025
-
Challenges and solutions for the delivery of biotech drugs-a review of drug nanocrystal technology and lipid nanoparticles
-
Muller R.H., and Keck C.M. Challenges and solutions for the delivery of biotech drugs-a review of drug nanocrystal technology and lipid nanoparticles. J Biotechnol 113 (2004) 151-170
-
(2004)
J Biotechnol
, vol.113
, pp. 151-170
-
-
Muller, R.H.1
Keck, C.M.2
-
42
-
-
4544383493
-
Nanosuspensions in drug delivery
-
Rabinow B.E. Nanosuspensions in drug delivery. Nat Rev Drug Discov 3 (2004) 785-796
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 785-796
-
-
Rabinow, B.E.1
-
43
-
-
0035803697
-
Organic nanoparticles in the aqueous phase-theory, experiment, and use
-
Horn D., and Rieger J. Organic nanoparticles in the aqueous phase-theory, experiment, and use. Angew Chem Int Ed 40 (2001) 4330-4361
-
(2001)
Angew Chem Int Ed
, vol.40
, pp. 4330-4361
-
-
Horn, D.1
Rieger, J.2
-
44
-
-
14144250911
-
Recent advances with liposomes as pharmaceutical carriers
-
Torchilin V.P. Recent advances with liposomes as pharmaceutical carriers. Nat Rev Drug Discov 4 (2005) 145-160
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 145-160
-
-
Torchilin, V.P.1
-
45
-
-
1942453805
-
Solid lipid nanoparticles for parenteral drug delivery
-
Wissing S.A., Kayser O., and Muller R.H. Solid lipid nanoparticles for parenteral drug delivery. Adv Drug Deliv Rev 56 (2004) 1257-1272
-
(2004)
Adv Drug Deliv Rev
, vol.56
, pp. 1257-1272
-
-
Wissing, S.A.1
Kayser, O.2
Muller, R.H.3
-
47
-
-
12144288634
-
Chemotherapy of glioblastoma in rats using doxorubicin-loaded nanoparticles
-
Steiniger S.C., Kreuter J., Khalansky A.S., Skidan I.N., Bobruskin A.I., Smirnova Z.S., et al. Chemotherapy of glioblastoma in rats using doxorubicin-loaded nanoparticles. Int J Cancer 109 (2004) 759-767
-
(2004)
Int J Cancer
, vol.109
, pp. 759-767
-
-
Steiniger, S.C.1
Kreuter, J.2
Khalansky, A.S.3
Skidan, I.N.4
Bobruskin, A.I.5
Smirnova, Z.S.6
-
48
-
-
4444379133
-
Nanoparticle and targeted systems for cancer therapy
-
Brannon-Peppas L., and Blanchette J.O. Nanoparticle and targeted systems for cancer therapy. Adv Drug Deliv Rev 56 (2004) 1649-1659
-
(2004)
Adv Drug Deliv Rev
, vol.56
, pp. 1649-1659
-
-
Brannon-Peppas, L.1
Blanchette, J.O.2
-
49
-
-
0037189380
-
Tumor regression by targeted gene delivery to the neovasculature
-
Hood J.D., Bednarski M., Frausto R., Guccione S., Reisfeld R.A., Xiang R., et al. Tumor regression by targeted gene delivery to the neovasculature. Science 296 (2002) 2404-2407
-
(2002)
Science
, vol.296
, pp. 2404-2407
-
-
Hood, J.D.1
Bednarski, M.2
Frausto, R.3
Guccione, S.4
Reisfeld, R.A.5
Xiang, R.6
-
50
-
-
17144433510
-
Enhanced transfection efficiency of a systemically delivered tumor-targeting immunolipoplex by inclusion of a pH-sensitive histidylated oligolysine peptide
-
Yu W., Pirollo K.F., Yu B., Rait A., Xiang L., Huang W., et al. Enhanced transfection efficiency of a systemically delivered tumor-targeting immunolipoplex by inclusion of a pH-sensitive histidylated oligolysine peptide. Nucleic Acids Res 32 (2004) e48
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Yu, W.1
Pirollo, K.F.2
Yu, B.3
Rait, A.4
Xiang, L.5
Huang, W.6
-
51
-
-
7444223607
-
Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells
-
Farokhzad O.C., Jon S., Khademhosseini A., Tran T.N., Lavan D.A., and Langer R. Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer Res 64 (2004) 7668-7672
-
(2004)
Cancer Res
, vol.64
, pp. 7668-7672
-
-
Farokhzad, O.C.1
Jon, S.2
Khademhosseini, A.3
Tran, T.N.4
Lavan, D.A.5
Langer, R.6
-
52
-
-
10644228142
-
Efficient cancer therapy with a nanobody-based conjugate
-
Cortez-Retamozo V., Backmann N., Senter P.D., Wernery U., De Baetselier P., Muyldermans S., et al. Efficient cancer therapy with a nanobody-based conjugate. Cancer Res 64 (2004) 2853-2857
-
(2004)
Cancer Res
, vol.64
, pp. 2853-2857
-
-
Cortez-Retamozo, V.1
Backmann, N.2
Senter, P.D.3
Wernery, U.4
De Baetselier, P.5
Muyldermans, S.6
-
53
-
-
12844258906
-
Dendrimers and dendritic polymers in drug delivery
-
Gillies E.R., and Frechet J.M. Dendrimers and dendritic polymers in drug delivery. Drug Discov Today 10 (2005) 35-43
-
(2005)
Drug Discov Today
, vol.10
, pp. 35-43
-
-
Gillies, E.R.1
Frechet, J.M.2
-
54
-
-
14544298301
-
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
-
Schiffelers R.M., Ansari A., Xu J., Zhou Q., Tang Q., Storm G., et al. Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res 32 (2004) e149
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Schiffelers, R.M.1
Ansari, A.2
Xu, J.3
Zhou, Q.4
Tang, Q.5
Storm, G.6
-
55
-
-
0141765891
-
The "right" size in nanobiotechnology
-
Whitesides G.M. The "right" size in nanobiotechnology. Nat Biotechnol 21 (2003) 1161-1165
-
(2003)
Nat Biotechnol
, vol.21
, pp. 1161-1165
-
-
Whitesides, G.M.1
-
56
-
-
19744382195
-
Electronic structure and bonding of Au on a SiO2 cluster: a nanobullet for tumors
-
Sun Q., Wang Q., Rao B.K., and Jena P. Electronic structure and bonding of Au on a SiO2 cluster: a nanobullet for tumors. Phys Rev Lett 93 (2004) 186803/1-186803/4
-
(2004)
Phys Rev Lett
, vol.93
-
-
Sun, Q.1
Wang, Q.2
Rao, B.K.3
Jena, P.4
-
57
-
-
7444253428
-
Systems biology and new technologies enable predictive and preventative medicine
-
Hood L., Heath J.R., Phelps M.E., and Lin B. Systems biology and new technologies enable predictive and preventative medicine. Science 306 (2004) 640-643
-
(2004)
Science
, vol.306
, pp. 640-643
-
-
Hood, L.1
Heath, J.R.2
Phelps, M.E.3
Lin, B.4
-
58
-
-
5044229321
-
The impact of systems approaches on biological problems in drug discovery
-
Hood L., and Perlmutter R.M. The impact of systems approaches on biological problems in drug discovery. Nat Biotechnol 22 (2004) 1215-1217
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1215-1217
-
-
Hood, L.1
Perlmutter, R.M.2
-
59
-
-
14044261316
-
Opinion: what's wrong with our cancer models?
-
Kamb A. Opinion: what's wrong with our cancer models?. Nat Rev Drug Discov 4 (2005) 161-165
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 161-165
-
-
Kamb, A.1
-
60
-
-
2442621619
-
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
-
Ferrara N., Hillan K.J., Gerber H.P., and Novotny W. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov 3 (2004) 391-400
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 391-400
-
-
Ferrara, N.1
Hillan, K.J.2
Gerber, H.P.3
Novotny, W.4
-
62
-
-
4944242884
-
A vision for the National Cancer Program in the United States
-
von Eschenbach A.C. A vision for the National Cancer Program in the United States. Nat Rev Cancer 4 (2004) 820-828
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 820-828
-
-
von Eschenbach, A.C.1
-
63
-
-
3142781225
-
Small-molecule inhibitors of protein-protein interactions: progressing towards the dream
-
Arkin M.R., and Wells J.A. Small-molecule inhibitors of protein-protein interactions: progressing towards the dream. Nat Rev Drug Discov 3 (2004) 301-317
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 301-317
-
-
Arkin, M.R.1
Wells, J.A.2
-
65
-
-
20844437061
-
A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design
-
Card G.L., Blasdel L., England B.P., Zhang C., Suzuki Y., Gillette S., et al. A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design. Nat Biotechnol 23 (2005) 201-207
-
(2005)
Nat Biotechnol
, vol.23
, pp. 201-207
-
-
Card, G.L.1
Blasdel, L.2
England, B.P.3
Zhang, C.4
Suzuki, Y.5
Gillette, S.6
-
67
-
-
11144320699
-
Navigating chemical space for biology and medicine
-
Lipinski C., and Hopkins A. Navigating chemical space for biology and medicine. Nature 432 (2004) 855-861
-
(2004)
Nature
, vol.432
, pp. 855-861
-
-
Lipinski, C.1
Hopkins, A.2
-
69
-
-
11144323163
-
Virtual screening of chemical libraries
-
Shoichet B.K. Virtual screening of chemical libraries. Nature 432 (2004) 862-865
-
(2004)
Nature
, vol.432
, pp. 862-865
-
-
Shoichet, B.K.1
-
70
-
-
0036635291
-
Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug
-
Capdeville R., Buchdunger E., Zimmermann J., and Matter A. Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug. Nat Rev Drug Discov 1 (2002) 493-502
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 493-502
-
-
Capdeville, R.1
Buchdunger, E.2
Zimmermann, J.3
Matter, A.4
-
71
-
-
4344623889
-
Imatinib as a paradigm of targeted therapies
-
Druker B.J. Imatinib as a paradigm of targeted therapies. Adv Cancer Res 91 (2004) 1-30
-
(2004)
Adv Cancer Res
, vol.91
, pp. 1-30
-
-
Druker, B.J.1
-
72
-
-
14744274624
-
Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance
-
Burgess M.R., Skaggs B.J., Shah N.P., Lee F.Y., and Sawyers C.L. Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance. Proc Natl Acad Sci U S A (2005)
-
(2005)
Proc Natl Acad Sci U S A
-
-
Burgess, M.R.1
Skaggs, B.J.2
Shah, N.P.3
Lee, F.Y.4
Sawyers, C.L.5
-
73
-
-
13844261144
-
A non-ATP-competitive inhibitor of BCR-ABL overrides imatinib resistance
-
Gumireddy K., Baker S.J., Cosenza S.C., John P., Kang A.D., Robell K.A., et al. A non-ATP-competitive inhibitor of BCR-ABL overrides imatinib resistance. Proc Natl Acad Sci U S A 102 (2005) 1992-1997
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 1992-1997
-
-
Gumireddy, K.1
Baker, S.J.2
Cosenza, S.C.3
John, P.4
Kang, A.D.5
Robell, K.A.6
-
74
-
-
3142676436
-
Overriding imatinib resistance with a novel ABL kinase inhibitor
-
Shah N.P., Tran C., Lee F.Y., Chen P., Norris D., and Sawyers C.L. Overriding imatinib resistance with a novel ABL kinase inhibitor. Science 305 (2004) 399-401
-
(2004)
Science
, vol.305
, pp. 399-401
-
-
Shah, N.P.1
Tran, C.2
Lee, F.Y.3
Chen, P.4
Norris, D.5
Sawyers, C.L.6
-
75
-
-
3242719541
-
Antisense strategies
-
Crooke S.T. Antisense strategies. Curr Mol Med 4 (2004) 465-487
-
(2004)
Curr Mol Med
, vol.4
, pp. 465-487
-
-
Crooke, S.T.1
-
76
-
-
12344303295
-
Antisense oligonucleotides targeted to the human alpha folate receptor inhibit breast cancer cell growth and sensitize the cells to doxorubicin treatment
-
Jhaveri M.S., Rait A.S., Chung K.N., Trepel J.B., and Chang E.H. Antisense oligonucleotides targeted to the human alpha folate receptor inhibit breast cancer cell growth and sensitize the cells to doxorubicin treatment. Mol Cancer Ther 3 (2004) 1505-1512
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 1505-1512
-
-
Jhaveri, M.S.1
Rait, A.S.2
Chung, K.N.3
Trepel, J.B.4
Chang, E.H.5
-
77
-
-
3242677639
-
siRNAs: applications in functional genomics and potential as therapeutics
-
Dorsett Y., and Tuschl T. siRNAs: applications in functional genomics and potential as therapeutics. Nat Rev Drug Discov 3 (2004) 318-329
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 318-329
-
-
Dorsett, Y.1
Tuschl, T.2
-
78
-
-
9144260199
-
Use of RNA interference libraries to investigate oncogenic signalling in mammalian cells
-
Downward J. Use of RNA interference libraries to investigate oncogenic signalling in mammalian cells. Oncogene 23 (2004) 8376-8383
-
(2004)
Oncogene
, vol.23
, pp. 8376-8383
-
-
Downward, J.1
-
79
-
-
3242656346
-
Silencing of disease-related genes by small interfering RNAs
-
Fuchs U., Damm-Welk C., and Borkhardt A. Silencing of disease-related genes by small interfering RNAs. Curr Mol Med 4 (2004) 507-517
-
(2004)
Curr Mol Med
, vol.4
, pp. 507-517
-
-
Fuchs, U.1
Damm-Welk, C.2
Borkhardt, A.3
-
80
-
-
2342537869
-
The promise of cancer vaccines
-
Gilboa E. The promise of cancer vaccines. Nat Rev Cancer 4 (2004) 401-411
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 401-411
-
-
Gilboa, E.1
-
81
-
-
0042470540
-
Does the immune system see tumors as foreign or self?
-
Pardoll D. Does the immune system see tumors as foreign or self?. Annu Rev Immunol 21 (2003) 807-839
-
(2003)
Annu Rev Immunol
, vol.21
, pp. 807-839
-
-
Pardoll, D.1
-
82
-
-
4644324025
-
Cancer immunotherapy: moving beyond current vaccines
-
Rosenberg S.A., Yang J.C., and Restifo N.P. Cancer immunotherapy: moving beyond current vaccines. Nat Med 10 (2004) 909-915
-
(2004)
Nat Med
, vol.10
, pp. 909-915
-
-
Rosenberg, S.A.1
Yang, J.C.2
Restifo, N.P.3
-
83
-
-
4344697146
-
Size-dependent immunogenicity: therapeutic and protective properties of nano-vaccines against tumors
-
Fifis T., Gamvrellis A., Crimeen-Irwin B., Pietersz G.A., Li J., Mottram P.L., et al. Size-dependent immunogenicity: therapeutic and protective properties of nano-vaccines against tumors. J Immunol 173 (2004) 3148-3154
-
(2004)
J Immunol
, vol.173
, pp. 3148-3154
-
-
Fifis, T.1
Gamvrellis, A.2
Crimeen-Irwin, B.3
Pietersz, G.A.4
Li, J.5
Mottram, P.L.6
-
84
-
-
8644225816
-
Introduction: thermal ablation therapy
-
Stauffer P.R., and Goldberg S.N. Introduction: thermal ablation therapy. Int J Hyperthermia 20 (2004) 671-677
-
(2004)
Int J Hyperthermia
, vol.20
, pp. 671-677
-
-
Stauffer, P.R.1
Goldberg, S.N.2
-
85
-
-
0038182397
-
Nanoscale photonics: nanoshells: gifts in a gold wrapper
-
Brongersma M.L. Nanoscale photonics: nanoshells: gifts in a gold wrapper. Nat Mater 2 (2003) 296-297
-
(2003)
Nat Mater
, vol.2
, pp. 296-297
-
-
Brongersma, M.L.1
-
86
-
-
0345686712
-
Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance
-
Hirsch L.R., Stafford R.J., Bankson J.A., Sershen S.R., Rivera B., Price R.E., et al. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc Natl Acad Sci U S A 100 (2003) 13549-13554
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 13549-13554
-
-
Hirsch, L.R.1
Stafford, R.J.2
Bankson, J.A.3
Sershen, S.R.4
Rivera, B.5
Price, R.E.6
-
87
-
-
2442692534
-
Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles
-
O'Neal D.P., Hirsch L.R., Halas N.J., Payne J.D., and West J.L. Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles. Cancer Lett 209 (2004) 171-176
-
(2004)
Cancer Lett
, vol.209
, pp. 171-176
-
-
O'Neal, D.P.1
Hirsch, L.R.2
Halas, N.J.3
Payne, J.D.4
West, J.L.5
-
88
-
-
16644382078
-
US NCI launches nanotechnology plan
-
Alper J. US NCI launches nanotechnology plan. Nat Biotechnol 22 (2004) 1335-1336
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1335-1336
-
-
Alper, J.1
-
89
-
-
12944271053
-
Cancer statistics, 2005
-
Jemal A., Murray T., Ward E., Samuels A., Tiwari R.C., Ghafoor A., et al. Cancer statistics, 2005. CA Cancer J Clin 55 (2005) 10-30
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 10-30
-
-
Jemal, A.1
Murray, T.2
Ward, E.3
Samuels, A.4
Tiwari, R.C.5
Ghafoor, A.6
-
90
-
-
23644433384
-
How cancer could be cured by 2015
-
Blagosklonny M.V. How cancer could be cured by 2015. Cell Cycle 4 (2005)
-
(2005)
Cell Cycle
, vol.4
-
-
Blagosklonny, M.V.1
|