Challenges and solutions for the delivery of biotech drugs - A review of drug nanocrystal technology and lipid nanoparticles

Journal of Biotechnology

Volumn 113, Issue 1-3, 2004, Pages 151-170

  Muller, Rainer H ^a   Keck, Cornelia M ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Delivery system; Drug targeting; Nanocrystals; PathFinder; Poor solubility; Solid lipid nanoparticles

Indexed keywords

BIOTECH DRUGS; PATHFINDER TECHNOLOGY;

ADSORPTION; BIOTECHNOLOGY; LIPIDS; NANOSTRUCTURED MATERIALS; PROTEINS; SOLUBILITY;

DRUG PRODUCTS;

ALPHA TOCOPHEROL; AMPHOTERICIN B; AMPHOTERICIN B LIPID COMPLEX; APOLIPOPROTEIN E; ATOVAQUONE; BROMOCRIPTINE MESILATE; CYCLOSPORIN A; DANAZOL; DAUNORUBICIN; DISSOCUBES; DOXORUBICIN; GALACTOSE; GLYCOCHOLATE SODIUM; GOSERELIN; INTRALIPID; ITRACONAZOLE; KETOCONAZOLE; LEUPRORELIN; LIPOFUNDIN; LIPOSOME; MACROGOL; MANNOSE; MONOCLONAL ANTIBODY; NANOPARTICLE; NANOPURE; NAPROXEN; PACLITAXEL; PHOSPHATIDYLCHOLINE; POLOXAMER; POLYMER; POLYSORBATE 80; POVIDONE; ROTE LISTE; SOLEMULS; STEALTH; TRIPTORELIN; UNCLASSIFIED DRUG;

ADSORPTION; AREA UNDER THE CURVE; BIOTECHNOLOGICAL PRODUCTION; BLOOD BRAIN BARRIER; BLOOD FLOW; CONFERENCE PAPER; COST BENEFIT ANALYSIS; CRYSTAL STRUCTURE; DRUG BIOAVAILABILITY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG FORMULARY; DRUG HALF LIFE; DRUG RELEASE; DRUG SOLUBILITY; DRUG TARGETING; EMULSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; INTESTINE; LIPID ABSORPTION; MACROPHAGE; MOLECULAR SIZE; MOLECULAR WEIGHT; PHYSICAL CHEMISTRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; QUALITY CONTROL; RETICULOENDOTHELIAL SYSTEM; TOXOPLASMOSIS; ZETA POTENTIAL;

BIOTECHNOLOGY; CRYSTALLIZATION; DRUG DELIVERY SYSTEMS; DRUG INDUSTRY; NANOTECHNOLOGY; PHARMACEUTICAL PREPARATIONS;

EID: 4544275025     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2004.06.007     Document Type: Conference Paper

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