-
1
-
-
0032950123
-
Physical stability of ethyl diatrizoate nanocrystalline suspension in steam sterilization
-
Na, G. C. et al. Physical stability of ethyl diatrizoate nanocrystalline suspension in steam sterilization. Pharm. Res. 16, 569-574 (1999).
-
(1999)
Pharm. Res.
, vol.16
, pp. 569-574
-
-
Na, G.C.1
-
2
-
-
0035803697
-
Organic nanoparticles in the aqueous phase-theory, experiment, and use
-
Horn, D. & Rieger, J. Organic nanoparticles in the aqueous phase-theory, experiment, and use. Angew. Chem. Int. Ed. 40, 4330-4361 (2001).
-
(2001)
Angew. Chem. Int. Ed.
, vol.40
, pp. 4330-4361
-
-
Horn, D.1
Rieger, J.2
-
3
-
-
0038032150
-
Solid lipid nanoparticles (SLN) for controlled drug delivery - A review of the state of the art
-
Muller, R. H. et al. Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art. Eur. J. Pharm. and Biopharm. 50. 161-177 (2000).
-
(2000)
Eur. J. Pharm. and Biopharm.
, vol.50
, pp. 161-177
-
-
Muller, R.H.1
-
4
-
-
0031024171
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
Lipinski, C. A., Lombardo, F., Dominy, B. & Feeney, P. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Reviews 23, 3-25 (1997).
-
(1997)
Adv. Drug Deliv. Reviews
, vol.23
, pp. 3-25
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.3
Feeney, P.4
-
6
-
-
0028216294
-
Microparticulates for ophthalmic drug delivery
-
Joshi, A. Microparticulates for ophthalmic drug delivery. J. Ocular Pharm. 10, 29-45 (1994).
-
(1994)
J. Ocular Pharm.
, vol.10
, pp. 29-45
-
-
Joshi, A.1
-
7
-
-
0031965225
-
Ophthalmic drug delivery systems-recent advances
-
LeBourlais, C. et al. Ophthalmic drug delivery systems-recent advances. Prog. Retinal and Eye Res. 17, 33-58 (1998).
-
(1998)
Prog. Retinal and Eye Res.
, vol.17
, pp. 33-58
-
-
LeBourlais, C.1
-
9
-
-
84891576608
-
-
Ch. 13.8 (John Wiley and Sons, New York)
-
Gad, S. C. Drug Safety Evaluation Ch. 13.8 (John Wiley and Sons, New York, 2002).
-
(2002)
Drug Safety Evaluation
-
-
Gad, S.C.1
-
10
-
-
0025011157
-
Control of crystal growth in drug suspensions. Part II: Influence of polymers on dissolution and crystallization during temperature cycling
-
Ziller, K. H & Rupprecht, H. H. Control of crystal growth in drug suspensions. Part II: influence of polymers on dissolution and crystallization during temperature cycling. Pharm Ind, 52, 1017-1022 (1990).
-
(1990)
Pharm. Ind.
, vol.52
, pp. 1017-1022
-
-
Ziller, K.H.1
Rupprecht, H.H.2
-
11
-
-
0004259290
-
-
3rd edn (eds Banker, G. S. & Rhodes C. T.) Ch. 9 (Marcel Dekker, New York)
-
Tabibi, S. E. & Rhodes, C. T. in Modern Pharmaceutics 3rd edn (eds Banker, G. S. & Rhodes C. T.) Ch. 9 (Marcel Dekker, New York, 1996).
-
(1996)
Modern Pharmaceutics
-
-
Tabibi, S.E.1
Rhodes, C.T.2
-
12
-
-
0004175417
-
-
(ed. Myerson, A. S.) (Butterworth-Heinemann, Boston)
-
Myerson, A. S. & Ginde, R. in Handbook of Industrial Crystallization (ed. Myerson, A. S.) 45-46 (Butterworth-Heinemann, Boston, 1992).
-
(1992)
Handbook of Industrial Crystallization
, pp. 45-46
-
-
Myerson, A.S.1
Ginde, R.2
-
13
-
-
0026407420
-
-
(eds Ramanarayanan, R. et al.) (AIChE Symposium Series, Vol. New York)
-
Garside, J. in Particle Design Via Crystallization (eds Ramanarayanan, R. et al.) 16-25 (AIChE Symposium Series, Vol. 87, New York, 1991).
-
(1991)
Particle Design Via Crystallization
, vol.87
, pp. 16-25
-
-
Garside, J.1
-
14
-
-
0342897023
-
Nanosuspensions for the formulation of poorly water soluble drugs. I. Preparation by a size reduction technique
-
Muller, R. H. & Peters, K. Nanosuspensions for the formulation of poorly water soluble drugs. I. Preparation by a size reduction technique. Int. J. Pharm. 160, 229-237 (1998).
-
(1998)
Int. J. Pharm.
, vol.160
, pp. 229-237
-
-
Muller, R.H.1
Peters, K.2
-
15
-
-
0033982674
-
Influence of high pressure homogenisation equipment on nanodispersions characteristics
-
Liedtke, S., Wissing, S., Muller, R. H. & Mader, K. Influence of high pressure homogenisation equipment on nanodispersions characteristics. Int. J. Pharm. 196, 183-185 (2000).
-
(2000)
Int. J. Pharm.
, vol.196
, pp. 183-185
-
-
Liedtke, S.1
Wissing, S.2
Muller, R.H.3
Mader, K.4
-
16
-
-
4544370432
-
Development of the new Gaulin Micro-Gap™ homogenizing valve
-
Pandolfe, W. D. Development of the new Gaulin Micro-Gap™ homogenizing valve. J. Dairy Sci. 65, 2035-2044 (1982).
-
(1982)
J. Dairy Sci.
, vol.65
, pp. 2035-2044
-
-
Pandolfe, W.D.1
-
17
-
-
2342576493
-
On the influence of geometric parameters of a combined orifice valve on the attainable mean droplet diameter during high-pressure homogenization
-
Schultz, S., Wagner, G. & Ulrich, J. On the influence of geometric parameters of a combined orifice valve on the attainable mean droplet diameter during high-pressure homogenization. Eng. Life Sci. 2, 337-340 (2002).
-
(2002)
Eng. Life Sci.
, vol.2
, pp. 337-340
-
-
Schultz, S.1
Wagner, G.2
Ulrich, J.3
-
18
-
-
0346442082
-
Homogenization Valve
-
US Patent 5,749,650
-
Kinney, R. R. et al. Homogenization valve. US Patent 5,749,650 (1998).
-
(1998)
-
-
Kinney, R.R.1
-
19
-
-
85005622363
-
Homogenization
-
Wilbey, A. Homogenization. J. Soc Dairy Tech. 45, 31-32 (1992).
-
(1992)
J. Soc. Dairy Tech.
, vol.45
, pp. 31-32
-
-
Wilbey, A.1
-
20
-
-
0003889197
-
-
(eds Muller, R. H., Benita, S. & Bohm, B.) (Medpharm Scientific, Stuttgart)
-
Jahnke, S. in Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs (eds Muller, R. H., Benita, S. & Bohm, B.) 177-200 (Medpharm Scientific, Stuttgart, 1998).
-
(1998)
Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs
, pp. 177-200
-
-
Jahnke, S.1
-
21
-
-
0023167982
-
High-pressure homogenization. Part I. Liquid-liquid dispersion in turbulence fields of high energy density
-
Mohr, K.-H. High-pressure homogenization. Part I. Liquid-liquid dispersion in turbulence fields of high energy density. J. Food Engineer. 6, 177-186 (1987).
-
(1987)
J. Food Engineer.
, vol.6
, pp. 177-186
-
-
Mohr, K.-H.1
-
22
-
-
0019668509
-
Effect of dispersed and continuous phase viscosity on droplet size of emulsions generated by homogenization
-
Pandolfe, W. D. Effect of dispersed and continuous phase viscosity on droplet size of emulsions generated by homogenization. J. Dispersion Sci. Tech. 2, 459-474 (1981).
-
(1981)
J. Dispersion Sci. Tech.
, vol.2
, pp. 459-474
-
-
Pandolfe, W.D.1
-
23
-
-
0001844298
-
Fundamentals of pharmaceutics
-
Huttenrauch, R. Fundamentals of pharmaceutics. Acta Pharm. Technol. 34, 1-10 (1988).
-
(1988)
Acta Pharm. Technol.
, vol.34
, pp. 1-10
-
-
Huttenrauch, R.1
-
24
-
-
0022534162
-
Entropy of processing: A new quantity for comparing the solid state disorder of pharmaceutical materials
-
Grant, D. & York, P. Entropy of processing: a new quantity for comparing the solid state disorder of pharmaceutical materials. Int. J. Pharmaceutics 30, 161-180 (1986).
-
(1986)
Int. J. Pharmaceutics
, vol.30
, pp. 161-180
-
-
Grant, D.1
York, P.2
-
25
-
-
0000847179
-
The use of thermal analysis in the assessment of crystal disruption
-
Duddu, S. P. & Grant, D. The use of thermal analysis in the assessment of crystal disruption. Thermochimica Acta. 248, 131-145 (1995)
-
(1995)
Thermochimica Acta
, vol.248
, pp. 131-145
-
-
Duddu, S.P.1
Grant, D.2
-
26
-
-
45449112311
-
Microprecipitation method for preparing submicron suspensions
-
US Patent 6,607,784 B2
-
Kipp, J. E. et al. Microprecipitation method for preparing submicron suspensions. US Patent 6,607,784 B2 (2003).
-
(2003)
-
-
Kipp, J.E.1
-
27
-
-
0037312695
-
Nanosizing: A formulation approach for poorly-water-soluble compounds
-
Merisko-Liversidge, E., Liversidge, G. G. & Cooper, E. Nanosizing: a formulation approach for poorly-water-soluble compounds. Eur. J. Pharm Sci. 18, 113-120 (2003).
-
(2003)
Eur. J. Pharm. Sci.
, vol.18
, pp. 113-120
-
-
Merisko-Liversidge, E.1
Liversidge, G.G.2
Cooper, E.3
-
28
-
-
0037189994
-
Enhanced drug dissolution using evaporative precipitation into aqueous solution
-
Sarkari, M. et al. Enhanced drug dissolution using evaporative precipitation into aqueous solution. Int. J. Pharm. 243, 17-31 (2002).
-
(2002)
Int. J. Pharm.
, vol.243
, pp. 17-31
-
-
Sarkari, M.1
-
29
-
-
0033965872
-
Preparation of a clofazimine nanosuspension for intravenous use and evaluation of its therapeutic efficacy in murine Mycobacterium avium infection
-
Peters, K. et al. Preparation of a clofazimine nanosuspension for intravenous use and evaluation of its therapeutic efficacy in murine Mycobacterium avium infection. J. Antimcrob. Chem. 45, 77-83 (2000).
-
(2000)
J. Antimcrob. Chem.
, vol.45
, pp. 77-83
-
-
Peters, K.1
-
30
-
-
0032850517
-
Sterility assurance of microspheres
-
Toguchi, H. Sterility assurance of microspheres. J. Contr. Rel. 62, 51-55 (1999)
-
(1999)
J. Contr. Rel.
, vol.62
, pp. 51-55
-
-
Toguchi, H.1
-
31
-
-
0030695406
-
Sterile filtration of NanoCrystal™ drug formulations
-
Zheng, J. Y. & Bosch, J. W. Sterile filtration of NanoCrystal™ drug formulations. Drug Develop. Ind. Pharm. 23, 1087-1093 (1997).
-
(1997)
Drug Develop. Ind. Pharm.
, vol.23
, pp. 1087-1093
-
-
Zheng, J.Y.1
Bosch, J.W.2
-
32
-
-
0037148679
-
Preparation and characterization of sterile and freeze-dried sub-200 nm nanoparticles
-
Konan, Y. N., Gurny, R. & Allemann, E. Preparation and characterization of sterile and freeze-dried sub-200 nm nanoparticles. Int. J. Pharm. 233, 239-252 (2002).
-
(2002)
Int. J. Pharm.
, vol.233
, pp. 239-252
-
-
Konan, Y.N.1
Gurny, R.2
Allemann, E.3
-
33
-
-
0032950123
-
Physical stability of ethyl diatrizoate nanocrystalline suspension in steam sterilization
-
Na, G. C., Stevens, H. J., Yuan, B. & Rajagopalan, N. Physical stability of ethyl diatrizoate nanocrystalline suspension in steam sterilization. Pharm. Res. 16, 569-574 (1999).
-
(1999)
Pharm. Res.
, vol.16
, pp. 569-574
-
-
Na, G.C.1
Stevens, H.J.2
Yuan, B.3
Rajagopalan, N.4
-
34
-
-
4544340967
-
-
2nd edn (eds Lieberman, H. A., Rieger, M. M.. & Banker, G. S.) (Marcel Dekker, New York)
-
Floyd, A. G. & Jain, S. in Pharmaceutical Dosage Forms, Disperse Systems 2nd edn Vol. 2 (eds Lieberman, H. A., Rieger, M. M.. & Banker, G. S.) 295-298 (Marcel Dekker, New York, 1996).
-
(1996)
Pharmaceutical Dosage Forms, Disperse Systems
, vol.2
, pp. 295-298
-
-
Floyd, A.G.1
Jain, S.2
-
35
-
-
0023628115
-
Formulation design and development of parenteral suspensions
-
Akers, M. J., Fites, A. L. & Robison, R. L. Formulation design and development of parenteral suspensions. J. Parenter. Sci. Tech. 41, 88-96 (1987).
-
(1987)
J. Parenter. Sci. Tech.
, vol.41
, pp. 88-96
-
-
Akers, M.J.1
Fites, A.L.2
Robison, R.L.3
-
37
-
-
0004108757
-
-
(eds Knapp, J. Z., Barber, T. A. & Lieberman, A) Ch. 5 (Marcel Dekker, New York)
-
Weiner, B. B. in Liquid- and Surface-Borne Particle Measurement Handbook (eds Knapp, J. Z., Barber, T. A. & Lieberman, A Ch. 5 (Marcel Dekker, New York, 1996).
-
(1996)
Liquid- and Surface-Borne Particle Measurement Handbook
-
-
Weiner, B.B.1
-
38
-
-
0004108757
-
-
(eds Knapp, J. Z., Barber, T. A. & Lieberman, A) Ch. 4 (Marcel Dekker, New York)
-
Lines, R. W. in Liquid- and Surface-Borne Particle Measurement Handbook (eds Knapp, J. Z., Barber, T. A. & Lieberman, A Ch. 4 (Marcel Dekker, New York, 1996).
-
(1996)
Liquid- and Surface-Borne Particle Measurement Handbook
-
-
Lines, R.W.1
-
39
-
-
4544305309
-
-
USP 27 The United States Pharmacopeia, United States Pharmacopeial Convention Inc. Rockville, Md. <788> Particulate Matter in Injections, Microscopic Particle Count Test
-
<788> Particulate Matter in Injections, Microscopic Particle Count Test. USP 27 The United States Pharmacopeia, United States Pharmacopeial Convention Inc. Rockville, Md. (2004).
-
(2004)
-
-
-
40
-
-
12244304167
-
Characterization of crystalline drug nanoparticles using atomic force microscopy and complementary techniques
-
Shi, H. G. et al. Characterization of crystalline drug nanoparticles using atomic force microscopy and complementary techniques. Pharm. Res. 20, 479-484 (2003).
-
(2003)
Pharm. Res.
, vol.20
, pp. 479-484
-
-
Shi, H.G.1
-
41
-
-
0242320535
-
Rapid assessment of sedimentation stability in dispersions using near infrared transmission measurements during centrifugation and oscillatory rheology
-
Kuentz, M. and Rothlisberger, D. Rapid assessment of sedimentation stability in dispersions using near infrared transmission measurements during centrifugation and oscillatory rheology. Eur. J. Pharm. Biopharm. 56, 355-361 (2003).
-
(2003)
Eur. J. Pharm. Biopharm.
, vol.56
, pp. 355-361
-
-
Kuentz, M.1
Rothlisberger, D.2
-
42
-
-
58149322190
-
Thermal analysis and calorimetric methods in the characterisation of polymorphs and solvates
-
Giron, D. Thermal analysis and calorimetric methods in the characterisation of polymorphs and solvates. Thermochim. Acta 248, 1-59 (1995).
-
(1995)
Thermochim. Acta
, vol.248
, pp. 1-59
-
-
Giron, D.1
-
43
-
-
0030950117
-
Application of differential scanning calorimetry to the estimation of drug purity: Various problems and their solutions in purity analysis
-
Yoshii, K. Application of differential scanning calorimetry to the estimation of drug purity: various problems and their solutions in purity analysis. Chem. Pharm. Bull. 45, 338-343 (1997).
-
(1997)
Chem. Pharm. Bull.
, vol.45
, pp. 338-343
-
-
Yoshii, K.1
-
44
-
-
0027814140
-
A review of the applications of thermal methods within the pharmaceutical industry
-
Barnes, A. F. et al. A review of the applications of thermal methods within the pharmaceutical industry. J. Thermal Anal. 40, 499-509 (1993).
-
(1993)
J. Thermal Anal.
, vol.40
, pp. 499-509
-
-
Barnes, A.F.1
-
45
-
-
0037446556
-
Spectroscopic approach for on-line monitoring of particle size during the processing of pharmaceutical nanoparticles
-
Higgins, J. P. Spectroscopic approach for on-line monitoring of particle size during the processing of pharmaceutical nanoparticles. Anal. Chem. 75, 1777-1785 (2003).
-
(2003)
Anal. Chem.
, vol.75
, pp. 1777-1785
-
-
Higgins, J.P.1
-
46
-
-
0034948871
-
Biorelevant dissolution testing to predict the plasma profile of lipophilic drugs after oral administration
-
Nicolaides, E. et al. Biorelevant dissolution testing to predict the plasma profile of lipophilic drugs after oral administration. Pharm. Res. 18, 380-388 (2001).
-
(2001)
Pharm. Res.
, vol.18
, pp. 380-388
-
-
Nicolaides, E.1
-
47
-
-
0033805179
-
Vitro-in vivo correlations for lipophilic, poorly water-soluble drugs
-
Dressman, J. B. & Reppas, C. In vitro-in vivo correlations for lipophilic, poorly water-soluble drugs. Euro. J. Pharm. Sci. 11 (Suppl. 2), S73-S80 (2000).
-
(2000)
Euro. J. Pharm. Sci.
, vol.11
, Issue.SUPPL. 2
-
-
Dressman, J.B.1
Reppas, C.2
-
48
-
-
84894500465
-
Guidance for Industry: Liposome Drug Products; Chemistry, manufacturing, and controls; Human pharmacokinetics and bioavailability; and labeling documentation
-
U. S. Dept. of Health and Human Services, Food and Drug Administration. August
-
U. S. Dept. of Health and Human Services, Food and Drug Administration. Guidance for Industry: Liposome Drug Products; Chemistry, manufacturing, and controls; human pharmacokinetics and bioavailability; and labeling documentation, August 2002.
-
(2002)
-
-
-
49
-
-
0003408403
-
-
2nd edn (eds Lieberman, H. A., Rieger, M. M. & Banker, G. S.) Ch. 8 (Marcel Dekker. New York)
-
Donovan, M. & Flanagan, D. in Pharmaceutical Dosage Forms, Disperse Systems 2nd edn Vol. 2. (eds Lieberman, H. A., Rieger, M. M. & Banker, G. S.) Ch. 8 (Marcel Dekker. New York, 1996).
-
(1996)
Pharmaceutical Dosage Forms, Disperse Systems
, vol.2
-
-
Donovan, M.1
Flanagan, D.2
-
50
-
-
0036689390
-
Effect of nanonization on absorption of 301029: Ex vivo and in vivo pharmacokinetic correlations determined by liquid chromatography/mass spectrometry
-
Jia, L., Wong, J., Cerna, C. & Weitman, S. Effect of nanonization on absorption of 301029: ex vivo and in vivo pharmacokinetic correlations determined by liquid chromatography/mass spectrometry. Pharm. Res. 19, 1091-1096(2002).
-
(2002)
Pharm. Res.
, vol.19
, pp. 1091-1096
-
-
Jia, L.1
Wong, J.2
Cerna, C.3
Weitman, S.4
-
51
-
-
0029080002
-
Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs
-
Liversidge, G. & Cundy, K. Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs. Int. J. Pharm. 125, 91-97 (1995).
-
(1995)
Int. J. Pharm.
, vol.125
, pp. 91-97
-
-
Liversidge, G.1
Cundy, K.2
-
52
-
-
0028824401
-
Drug particle size reduction for decreasing gastric irritancy and enhancing absorption of naproxen in rats
-
Liversidge, G. G. & Conzentino, P. Drug particle size reduction for decreasing gastric irritancy and enhancing absorption of naproxen in rats. Int. J. Pharm. 125, 309-313 (1995).
-
(1995)
Int. J. Pharm.
, vol.125
, pp. 309-313
-
-
Liversidge, G.G.1
Conzentino, P.2
-
54
-
-
0030471901
-
Gastrointestinal uptake of biodegradable microparticles: Effect of particle size
-
Desai, M. P. Gastrointestinal uptake of biodegradable microparticles: effect of particle size. Pharm. Res. 13, 1838-1845 (1996).
-
(1996)
Pharm. Res.
, vol.13
, pp. 1838-1845
-
-
Desai, M.P.1
-
55
-
-
0345267135
-
Bioadhesion of solid oral dosage forms, why and how?
-
Duchene, D. & Ponchel, G. Bioadhesion of solid oral dosage forms, why and how? Eur. J. Pharm. and Biopharm. 44, 15-23 (1997).
-
(1997)
Eur. J. Pharm. and Biopharm.
, vol.44
, pp. 15-23
-
-
Duchene, D.1
Ponchel, G.2
-
56
-
-
0036692366
-
Comparative uptake studies of bioadhesive and nonbioadhesive nanoparticles in human intestinal cell lines and rats: The effect of mucus on particle adsorption and transport
-
Behrens, I., Pena, A. I, Alonso, M. J. & Kissel, T. Comparative uptake studies of bioadhesive and nonbioadhesive nanoparticles in human intestinal cell lines and rats: the effect of mucus on particle adsorption and transport. Pharm. Res. 19, 1185-1193 (2002).
-
(2002)
Pharm. Res.
, vol.19
, pp. 1185-1193
-
-
Behrens, I.1
Pena, A.I.2
Alonso, M.J.3
Kissel, T.4
-
57
-
-
0035478442
-
Transcytosis of nanoparticle and dendrimer delivery systems: Evolving vistas
-
Florence, A. T. & Hussain, N. Transcytosis of nanoparticle and dendrimer delivery systems: evolving vistas. Adv. Drug Del. Rev. 50, S69-S89 (2001).
-
(2001)
Adv. Drug Del. Rev.
, vol.50
-
-
Florence, A.T.1
Hussain, N.2
-
58
-
-
0034872426
-
Size dependent bioadhesion of micro-and nanoparticulate carriers to the inflamed colonic mucosa
-
Lamprecht, A., Schafer, U. & Lehr, C-M. Size dependent bioadhesion of micro-and nanoparticulate carriers to the inflamed colonic mucosa. Pharm Res. 18, 788-794 (2001).
-
(2001)
Pharm. Res.
, vol.18
, pp. 788-794
-
-
Lamprecht, A.1
Schafer, U.2
Lehr, C.-M.3
-
59
-
-
0035478442
-
Transcytosis of nanoparticle and dendrimer delivery systems: Evolving vistas
-
Florence, A. T. & Hussain, N. Transcytosis of nanoparticle and dendrimer delivery systems: evolving vistas. Adv. Drug Del. Rev. 50, S69-S89 (2001).
-
(2001)
Adv. Drug Del. Rev.
, vol.50
-
-
Florence, A.T.1
Hussain, N.2
-
60
-
-
0025674686
-
Nanoparticle uptake by the rat gastrointestinal mucosa: Quantitation and particle size dependency
-
Jani, P., Halbert, G., Langridge, J. & Florence, A. Nanoparticle uptake by the rat gastrointestinal mucosa: quantitation and particle size dependency. J. Pharm. Pharmacol. 42, 821-826 (1990).
-
(1990)
J. Pharm. Pharmacol.
, vol.42
, pp. 821-826
-
-
Jani, P.1
Halbert, G.2
Langridge, J.3
Florence, A.4
-
61
-
-
0035940089
-
Exploiting M cells for drug and vaccine delivery
-
Clark, M., Jepson, M. & Hirst, B. Exploiting M cells for drug and vaccine delivery. Adv. Drug Deliv. Rev. 50, 81-106 (2001).
-
(2001)
Adv. Drug Deliv. Rev.
, vol.50
, pp. 81-106
-
-
Clark, M.1
Jepson, M.2
Hirst, B.3
-
62
-
-
0004023213
-
-
(eds Charman, W. N. & Stella, V. J.) (CRC, Florida)
-
O'Driscoll, C. M. in Lymphatic Transport of Drugs (eds Charman, W. N. & Stella, V. J.) 1-35 (CRC, Florida, 1992).
-
(1992)
Lymphatic Transport of Drugs
, pp. 1-35
-
-
O'Driscoll, C.M.1
-
63
-
-
0032586956
-
12-mediated transport of nanoparticles across Caco-2 cells
-
12-mediated transport of nanoparticles across Caco-2 cells. Int. J. Pharm. 179, 247-255 (1999).
-
(1999)
Int. J. Pharm.
, vol.179
, pp. 247-255
-
-
Russell-Jones, G.J.1
-
64
-
-
0036234785
-
Intravenous administration of poorly soluble new drug entities in early durg discovery: The potential impact of formulatin on pharmacokinetic parameters
-
Bittner, B. & Mountfield, R. J., Intravenous administration of poorly soluble new drug entities in early durg discovery: the potential impact of formulatin on pharmacokinetic parameters. Curr. Opinion Drug Discov. Dev. 5, 59-71 (2002).
-
(2002)
Curr. Opinion Drug Discov. Dev.
, vol.5
, pp. 59-71
-
-
Bittner, B.1
Mountfield, R.J.2
-
65
-
-
0029089799
-
Anaphylactoid reactions in children receiving high-dose intravenous cyclosporine for reversal of tumor resistance: The causative role of improper dissolution of cremophor EL
-
Theis, J. G. et al. Anaphylactoid reactions in children receiving high-dose intravenous cyclosporine for reversal of tumor resistance:the causative role of improper dissolution of cremophor EL. J. Clin. Oncol. 13, 2508-2516 (1995).
-
(1995)
J. Clin. Oncol.
, vol.13
, pp. 2508-2516
-
-
Theis, J.G.1
-
66
-
-
0021215579
-
Hypersensitivity reactions induced by etoposide
-
O'Dwyer, P. J. & Weiss, R. B. Hypersensitivity reactions induced by etoposide. Cancer Res. 68, 959-961 (1984).
-
(1984)
Cancer Res.
, vol.68
, pp. 959-961
-
-
O'Dwyer, P.J.1
Weiss, R.B.2
-
67
-
-
0006573092
-
-
2nd edn (eds Avis, K. E., Lieberman, H. A. & Lachman, L.) (Marcel Dekker, New York)
-
Duma, R. J., Akers, M. J. & Turco, S. J. in Pharmaceutical Dosage Forms: Parenteral Medications 2nd edn Vol. 1 (eds Avis, K. E., Lieberman, H. A. & Lachman, L.) 17-58 (Marcel Dekker, New York, 1992 ).
-
(1992)
Pharmaceutical Dosage Forms: Parenteral Medications
, vol.1
, pp. 17-58
-
-
Duma, R.J.1
Akers, M.J.2
Turco, S.J.3
-
68
-
-
0027228097
-
Studies in Phlebitis. VI. Dilution-induced precipitation of amiodarone HCI
-
Ward, G. H. & Yalkowsky, S. H. Studies in Phlebitis. VI. Dilution-induced precipitation of amiodarone HCI. J. Parenter. Sci. Technol. 47, 161-165 (1993).
-
(1993)
J. Parenter. Sci. Technol.
, vol.47
, pp. 161-165
-
-
Ward, G.H.1
Yalkowsky, S.H.2
-
69
-
-
0025962722
-
Precipitation of the renin inhibitor ditekiren upon iv infusion; In vitro studies and their relationship to in vivo precipitation in the cynomolgus monkey
-
Davio, S. R. et al. Precipitation of the renin inhibitor ditekiren upon iv infusion; in vitro studies and their relationship to in vivo precipitation in the cynomolgus monkey. Pharm. Res. 8, 80-83 (1991).
-
(1991)
Pharm. Res.
, vol.8
, pp. 80-83
-
-
Davio, S.R.1
-
70
-
-
0023613416
-
Lipid emulsions as drug delivery systems
-
Davis, S. S. et al. Lipid emulsions as drug delivery systems. Ann. NY Acad. Sci. 507, 76-78 (1987b).
-
(1987)
Ann. NY Acad. Sci.
, vol.507
, pp. 76-78
-
-
Davis, S.S.1
-
72
-
-
9044235775
-
Formulation and antitumor activity evaluation of nanocrystalline suspensions of poorly soluble anticancer drugs
-
Merisko-Liversidge, E. Formulation and antitumor activity evaluation of nanocrystalline suspensions of poorly soluble anticancer drugs. Pharm. Res. 13, 272-278 (1996).
-
(1996)
Pharm. Res.
, vol.13
, pp. 272-278
-
-
Merisko-Liversidge, E.1
-
73
-
-
0028308546
-
Ultra-long duration local anesthesia produced by injection of lecithin-coated tetracaine microcrystals
-
Boedeker, B. H., Logeski, E., Kline, M. & Haynes, D. Ultra-long duration local anesthesia produced by injection of lecithin-coated tetracaine microcrystals. J. Clin Pharmacol. 34, 699-702 (1994).
-
(1994)
J. Clin. Pharmacol.
, vol.34
, pp. 699-702
-
-
Boedeker, B.H.1
Logeski, E.2
Kline, M.3
Haynes, D.4
-
74
-
-
0029972629
-
Intravenous lecithin-coated microcrystals of dantrolene are effective in the treatment of malignant hyperthermia: An investigation in rats, dogs, and swine
-
Karan, S. M. et al. Intravenous lecithin-coated microcrystals of dantrolene are effective in the treatment of malignant hyperthermia:an investigation in rats, dogs, and swine. Anesth. Analg. 82, 796-802 (1996).
-
(1996)
Anesth. Analg.
, vol.82
, pp. 796-802
-
-
Karan, S.M.1
-
75
-
-
0023121181
-
Treatment of cancer pain with epidural butylamino benzoate suspension
-
Shulman, M. Treatment of cancer pain with epidural butylamino benzoate suspension. Reg. Anesth. 12, 1-4 (1987).
-
(1987)
Reg. Anesth.
, vol.12
, pp. 1-4
-
-
Shulman, M.1
-
76
-
-
0006014154
-
Tissue distribution and plasma clearance of a novel microcrystal-encapsulated flurbiprofen formulation
-
Clement, M. A. et al. Tissue distribution and plasma clearance of a novel microcrystal-encapsulated flurbiprofen formulation. The Pharmacologist 34, 204 (1992).
-
(1992)
The Pharmacologist
, vol.34
, pp. 204
-
-
Clement, M.A.1
-
77
-
-
0028200490
-
Hydrosols: Alternatives for the parenteral application of poorly water soluble drugs
-
Gassmann, P. et al. Hydrosols: Alternatives for the parenteral application of poorly water soluble drugs. Eur. J. Pharm. Biopharm. 40, 64-72 (1994).
-
(1994)
Eur. J. Pharm. Biopharm.
, vol.40
, pp. 64-72
-
-
Gassmann, P.1
-
78
-
-
0026567842
-
Similar central actions of intravenous methohexitone suspension and solution in the rabbit
-
Viernstein, J. & Stumpf, C. Similar central actions of intravenous methohexitone suspension and solution in the rabbit. J. Pharm. Pharmacol. 44, 66-68 (1992).
-
(1992)
J. Pharm. Pharmacol.
, vol.44
, pp. 66-68
-
-
Viernstein, J.1
Stumpf, C.2
-
79
-
-
4544226250
-
Microcrystal technology-based sustained delivery of nifedipine in rats
-
Parikh, I. et al. Microcrystal technology-based sustained delivery of nifedipine in rats. The Pharmacologist 33, 197 (1991).
-
(1991)
The Pharmacologist
, vol.33
, pp. 197
-
-
Parikh, I.1
-
80
-
-
0023804439
-
Release and absorption rate aspects of intramuscularly injected pharmaceuticals
-
Zuidema, J., Pieters. F. A. & Duchateau, G. Release and absorption rate aspects of intramuscularly injected pharmaceuticals. Int. J. Pharm. 47, 1-12 (1988).
-
(1988)
Int. J. Pharm.
, vol.47
, pp. 1-12
-
-
Zuidema, J.1
Pieters, F.A.2
Duchateau, G.3
-
81
-
-
0026601351
-
Dissolution performance related to particle size distribution for commercially available prednisolone acetate suspensions
-
Stout, P. J. M. et al. Dissolution performance related to particle size distribution for commercially available prednisolone acetate suspensions. Drug Development Ind. Pharm. 18, 395-408 (1992).
-
(1992)
Drug Development Ind. Pharm.
, vol.18
, pp. 395-408
-
-
Stout, P.J.M.1
-
82
-
-
0034996764
-
Long-circulating and target-specific nanoparticles: Theory to practice
-
Moghimi, S. M., Hunter, A. C. & Murray, J. C. Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol. Rev. 53, 283-318 (2001).
-
(2001)
Pharmacol. Rev.
, vol.53
, pp. 283-318
-
-
Moghimi, S.M.1
Hunter, A.C.2
Murray, J.C.3
-
83
-
-
0030802359
-
Endocytosis
-
Mukherjee, S., Ghosh, R. N. & Maxfield, F. R. Endocytosis. Physiol. Rev. 77, 759-803 (1997).
-
(1997)
Physiol. Rev.
, vol.77
, pp. 759-803
-
-
Mukherjee, S.1
Ghosh, R.N.2
Maxfield, F.R.3
-
84
-
-
0037378033
-
In vivo pharmacodynamics of antifungal drugs in treatment of candidiasis
-
Andes, D. et al. In vivo pharmacodynamics of antifungal drugs in treatment of candidiasis, Antimicrob. Agents Chemother. 47, 1179-1186 (2003).
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 1179-1186
-
-
Andes, D.1
-
85
-
-
4544347879
-
Enhanced efficacy of NANOEDGE itraconazole nanosuspension in an immunosuppressed rat model infected with an itraconazole-resistant C. albicans strain
-
AR6184
-
Rabinow, B. E. et al. Enhanced efficacy of NANOEDGE itraconazole nanosuspension in an immunosuppressed rat model infected with an itraconazole-resistant C. albicans strain. Am. Assoc. Pharma. Scientists AR6184 (2003).
-
(2003)
Am. Assoc. Pharma. Scientists
-
-
Rabinow, B.E.1
-
86
-
-
4544331527
-
Pharmacokinetics of a 14 day course of itraconazole nanocrystals given intravenously to allogeneic haematopoietic stem cell transplant (HCST) recipients
-
Donnelly, J. P. et al. Pharmacokinetics of a 14 day course of itraconazole nanocrystals given intravenously to allogeneic haematopoietic stem cell transplant (HCST) recipients. 41st Intersci. Conf. Antimicrob. Agents Chemother. A32 (2001).
-
(2001)
41st Intersci. Conf. Antimicrob. Agents Chemother.
-
-
Donnelly, J.P.1
-
87
-
-
4544252190
-
Sporanox (Itraconazole) injection: Approved labeling
-
(Thomson PDR, Montvale)
-
Sporanox (Itraconazole) injection: approved labeling. Physicians' Desk Reference 1772-1776 (Thomson PDR, Montvale, 2004).
-
(2004)
Physicians' Desk Reference
, pp. 1772-1776
-
-
-
88
-
-
0034955068
-
Itraconazole oral solution and intravenous formulations: A review of pharmacokinetics and pharmacodynamics
-
Willems, L., van der Geest, R. & de Beule, K. Itraconazole oral solution and intravenous formulations: a review of pharmacokinetics and pharmacodynamics. J. Clin. Pharm. Ther. 26, 159-169 (2001).
-
(2001)
J. Clin. Pharm. Ther.
, vol.26
, pp. 159-169
-
-
Willems, L.1
van der Geest, R.2
de Beule, K.3
-
89
-
-
0033965713
-
Time course of nodal enhancement with CT X-ray nanoparticle contrast agents: Effect of particle size and chemical structure
-
McIntire, G. L. et al. Time course of nodal enhancement with CT X-ray nanoparticle contrast agents: effect of particle size and chemical structure. Investigative Radiol. 35, 91-96 (2000).
-
(2000)
Investigative Radiol.
, vol.35
, pp. 91-96
-
-
McIntire, G.L.1
-
90
-
-
4544295543
-
Materials and methods for making improved micelle compositions; Lipid bonded to water soluble polymer
-
US Patent 6,217,886
-
Onyuksel, H. & Rubinstein, I. Materials and methods for making improved micelle compositions; lipid bonded to water soluble polymer. US Patent 6,217,886 (2001).
-
(2001)
-
-
Onyuksel, H.1
Rubinstein, I.2
-
91
-
-
0027242138
-
Increased microvascular permeability contributes to preferential accumulation of stealth liposomes in tumor tissue
-
Wu, N. et al. Increased microvascular permeability contributes to preferential accumulation of stealth liposomes in tumor tissue. Cancer Res. 53, 3765-3770 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 3765-3770
-
-
Wu, N.1
-
93
-
-
0027222948
-
Deposition patterns of aerosolized drugs within the human lungs
-
Martonen, T. B. & Katz, I. M. Deposition patterns of aerosolized drugs within the human lungs. Pharm. Res. 10, 871-878 (1993).
-
(1993)
Pharm. Res.
, vol.10
, pp. 871-878
-
-
Martonen, T.B.1
Katz, I.M.2
-
94
-
-
0023874113
-
Development of a systematic theory of suspension inhalation aerosols. II. Aggregates of monodisperse particles nebulized in polydisperse droplets
-
Chan, H.-K. & Gonda, I. Development of a systematic theory of suspension inhalation aerosols. II. Aggregates of monodisperse particles nebulized in polydisperse droplets. Int. J. Pharm. 41, 147-157 (1988).
-
(1988)
Int. J. Pharm.
, vol.41
, pp. 147-157
-
-
Chan, H.-K.1
Gonda, I.2
-
95
-
-
0030614519
-
Nebulization of NanoCrystals™: Production of a respirable solid-in-liquid-in-air colloidal dispersion
-
Wiedmann, T. S., DeCastro, L. & Wood, R. W. Nebulization of NanoCrystals™: Production of a respirable solid-in-liquid-in-air colloidal dispersion. Pharm. Res. 14, 112-116 (1997).
-
(1997)
Pharm. Res.
, vol.14
, pp. 112-116
-
-
Wiedmann, T.S.1
DeCastro, L.2
Wood, R.W.3
-
96
-
-
0032711216
-
An in vitro assessment of a NanoCrystal™ beclomethasone dipropionate colloidal dispersion via ultrasonic nebulization
-
Ostrander, K. D., Bosch, H. & Bondanza, D. An in vitro assessment of a NanoCrystal™ beclomethasone dipropionate colloidal dispersion via ultrasonic nebulization. Eur. J. Pharm. and Biopharm. 48, 207-215 (1999).
-
(1999)
Eur. J. Pharm. and Biopharm.
, vol.48
, pp. 207-215
-
-
Ostrander, K.D.1
Bosch, H.2
Bondanza, D.3
-
97
-
-
0347537277
-
Nebulizer nanosuspensions: Important device and formulation interactions
-
Keller, M., Jauernig, J., Lintz, F-C. & Knoch, M. Nebulizer nanosuspensions: important device and formulation interactions. Resp. Drug Delivery VIII, 197-206 (2002).
-
(2002)
Resp. Drug Delivery VIII
, pp. 197-206
-
-
Keller, M.1
Jauernig, J.2
Lintz, F.-C.3
Knoch, M.4
-
98
-
-
0036176196
-
Production and characterization of a budesonide nanosuspension for pulmonary administration
-
Jacobs, C. & Muller, R. H. Production and characterization of a budesonide nanosuspension for pulmonary administration. Pharm. Res. 19, 189-194 (2002).
-
(2002)
Pharm. Res.
, vol.19
, pp. 189-194
-
-
Jacobs, C.1
Muller, R.H.2
-
99
-
-
0037426696
-
Nebulization of biodegradable nanoparticles: Impact of nebulizer technology and nanoparticle characteristics on aerosol features
-
Dailey, L. A. et al. Nebulization of biodegradable nanoparticles: impact of nebulizer technology and nanoparticle characteristics on aerosol features. J. Control. Rel. 86, 131-144 (2003).
-
(2003)
J. Control Rel.
, vol.86
, pp. 131-144
-
-
Dailey, L.A.1
-
100
-
-
0347625573
-
The pharmacokinetics of nebulized nanocrystal budesonide suspension in healthy volunteers
-
Kraft, W. K. et al. The pharmacokinetics of nebulized nanocrystal budesonide suspension in healthy volunteers. J. Clin. Pharmacol. 44, 67-72 (2004).
-
(2004)
J. Clin. Pharmacol.
, vol.44
, pp. 67-72
-
-
Kraft, W.K.1
-
101
-
-
0034781469
-
Inhalable microparticles containing drug combinations to target alveolar macrophages for treatment of pulmonary tuberculosis
-
Sharma, R., Saxena, D., Dwivedi, A. & Misra, A. Inhalable microparticles containing drug combinations to target alveolar macrophages for treatment of pulmonary tuberculosis. Pharm. Res. 18, 1405-1410 (2001).
-
(2001)
Pharm. Res.
, vol.18
, pp. 1405-1410
-
-
Sharma, R.1
Saxena, D.2
Dwivedi, A.3
Misra, A.4
-
102
-
-
0347418154
-
Design of liposomal aerosols for improved delivery of rifampicin to alveolar macrophages
-
Vyas, S. P., Kannan, M., Jain, S., Mishra, V. & Singh, P. Design of liposomal aerosols for improved delivery of rifampicin to alveolar macrophages. Int. J. Pharm. 269, 37-49 (2004).
-
(2004)
Int. J. Pharm.
, vol.269
, pp. 37-49
-
-
Vyas, S.P.1
Kannan, M.2
Jain, S.3
Mishra, V.4
Singh, P.5
-
103
-
-
0035140581
-
Microparticulate uptake mechanims of in-vitro cell culture models of the respiratory epithelium
-
Foster, K. A., Yazdanian, M. & Audus, K. Microparticulate uptake mechanims of in-vitro cell culture models of the respiratory epithelium. J. Pharm. Pharmacol. 53, 57-66 (2001).
-
(2001)
J. Pharm. Pharmacol.
, vol.53
, pp. 57-66
-
-
Foster, K.A.1
Yazdanian, M.2
Audus, K.3
-
104
-
-
10744227569
-
Large porous particles for pulmonary drug delivery
-
Edwards, D. A. Large porous particles for pulmonary drug delivery. Science 276, 1868-1871 (1997).
-
(1997)
Science
, vol.276
, pp. 1868-1871
-
-
Edwards, D.A.1
-
105
-
-
0032509910
-
Relating the phagocytosis of microparticles by alveolar macrophages to surface chemistry: The effect of 1,2-dipalmitoylphosphatidylcholine
-
Evora, C. et al. Relating the phagocytosis of microparticles by alveolar macrophages to surface chemistry: the effect of 1,2-dipalmitoylphosphatidylcholine. J. Contr. Rel. 51, 143-152 (1998).
-
(1998)
J. Contr. Rel.
, vol.51
, pp. 143-152
-
-
Evora, C.1
-
106
-
-
0037126053
-
Trojan particles: Large porous carriers of nanoparticles for drug delivery
-
Tsapis, N., Bennett, D., Jackson, B., Weitz, D. & Edwards, D. Trojan particles: large porous carriers of nanoparticles for drug delivery. Proc. Natl Acad. Sci. USA. 99, 12001-12005 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12001-12005
-
-
Tsapis, N.1
Bennett, D.2
Jackson, B.3
Weitz, D.4
Edwards, D.5
-
108
-
-
0033507584
-
Intrathecal busulfan treatment of human neoplastic meningitis in athymic nude rats
-
Archer, G. E. et al. Intrathecal busulfan treatment of human neoplastic meningitis in athymic nude rats. J. Neuro-Oncology. 44, 233-241 (1999).
-
(1999)
J. Neuro-Oncology
, vol.44
, pp. 233-241
-
-
Archer, G.E.1
-
109
-
-
0025039720
-
Effect of epidural and subarachnoid injections of a 10% butamben suspension
-
Shulman, M., Hoseph, N. J. & Haller, C. A. Effect of epidural and subarachnoid injections of a 10% butamben suspension. Reg. Anesth. 15, 142-146 (1990).
-
(1990)
Reg. Anesth.
, vol.15
, pp. 142-146
-
-
Shulman, M.1
Hoseph, N.J.2
Haller, C.A.3
-
110
-
-
0033734065
-
High intratumoural accumulation of stealth® liposomal doxorubicin (Caelyx®) in glioblastomas and in metastatic brain tumours
-
Koukourakis, M. et al. High intratumoural accumulation of stealth® liposomal doxorubicin (Caelyx®) in glioblastomas and in metastatic brain tumours. Brit. J. Cancer 83, 1281-1286 (2000).
-
(2000)
Brit. J. Cancer
, vol.83
, pp. 1281-1286
-
-
Koukourakis, M.1
-
111
-
-
0035937595
-
Nanoparticulate systems for brain delivery of drugs
-
Kreuter, J. Nanoparticulate systems for brain delivery of drugs. Adv. Drug Deliv. Reviews 47, 65-81 (2001).
-
(2001)
Adv. Drug Deliv. Reviews
, vol.47
, pp. 65-81
-
-
Kreuter, J.1
-
112
-
-
0035910874
-
The role of plasma proteins in brain targeting: Species dependent protein adsorption patterns on brain-specific lipid drug conjugate (LDC) nanoparticles
-
Gessner, A., Olbrich, C., Schroder, W., Kayser, O. & Muller, R. H. The role of plasma proteins in brain targeting: species dependent protein adsorption patterns on brain-specific lipid drug conjugate (LDC) nanoparticles. Int. J. Pharm. 214, 87-91 (2001).
-
(2001)
Int. J. Pharm.
, vol.214
, pp. 87-91
-
-
Gessner, A.1
Olbrich, C.2
Schroder, W.3
Kayser, O.4
Muller, R.H.5
-
113
-
-
0343267787
-
Nanoparticles, a drug carrier system to pass the blood-brain barrier, permit central analgesic effects of i.v. dalargin injections
-
Schroder, U. & Sabel, B. A. Nanoparticles, a drug carrier system to pass the blood-brain barrier, permit central analgesic effects of i.v. dalargin injections. Brain Res. 710, 121-124 (1996).
-
(1996)
Brain Res.
, vol.710
, pp. 121-124
-
-
Schroder, U.1
Sabel, B.A.2
-
114
-
-
0003408403
-
-
2nd edn (Lieberman, H. A., Rieger, M. M. & Banker, G. S.) Ch. 4 (Marcel Dekker, New York)
-
Vanderhoff, J. W. in Pharmaceutical Dosage Forms, Disperse Systems 2nd edn Vol. 2 (Lieberman, H. A., Rieger, M. M. & Banker, G. S.) Ch. 4 (Marcel Dekker, New York, 1996).
-
(1996)
Pharmaceutical Dosage Forms, Disperse Systems
, vol.2
-
-
Vanderhoff, J.W.1
|