-
1
-
-
0033057177
-
The carcinoembryonic antigen (CEA) family: Structures, suggested functions and expression in normal and malignant tissues
-
Hammarstrom S. The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. Semin Cancer Biol 1999; 9:67-81.
-
(1999)
Semin Cancer Biol
, vol.9
, pp. 67-81
-
-
Hammarstrom, S.1
-
2
-
-
0035524114
-
Improving the efficacy of antibody-based cancer therapies
-
Carter P. Improving the efficacy of antibody-based cancer therapies. Nat Rev Cancer 2001;1:118-29.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 118-129
-
-
Carter, P.1
-
3
-
-
0033571383
-
High thermal stability is essential for tumor targeting of antibody fragments: Engineering of a humanized anti-epithelial glycoprotein-2 (epithelial cell adhesion molecule) single-chain Fv fragment
-
Willuda J, Honegger A, Waibel R, et al. High thermal stability is essential for tumor targeting of antibody fragments: engineering of a humanized anti-epithelial glycoprotein-2 (epithelial cell adhesion molecule) single-chain Fv fragment. Cancer Res 1999;59:5758-67.
-
(1999)
Cancer Res
, vol.59
, pp. 5758-5767
-
-
Willuda, J.1
Honegger, A.2
Waibel, R.3
-
4
-
-
0027332881
-
An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability
-
Whitlow M, Bell BA, Feng SL, et al. An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability. Protein Eng 1993;6:989-95.
-
(1993)
Protein Eng
, vol.6
, pp. 989-995
-
-
Whitlow, M.1
Bell, B.A.2
Feng, S.L.3
-
5
-
-
0028962371
-
A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks
-
Greenberg AS, Avila D, Hughes M, Hughes A, McKinney EC, Flajnik MF. A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks. Nature (Lond) 1995;374:168-73.
-
(1995)
Nature (Lond)
, vol.374
, pp. 168-173
-
-
Greenberg, A.S.1
Avila, D.2
Hughes, M.3
Hughes, A.4
McKinney, E.C.5
Flajnik, M.F.6
-
6
-
-
0034830063
-
Isolation of the new antigen receptor from wobbegong sharks, and use as a scaffold for the display of protein loop libraries
-
Nuttall SD, Krishnan UV, Hattarki M, De Gori R, Irving RA, Hudson PJ. Isolation of the new antigen receptor from wobbegong sharks, and use as a scaffold for the display of protein loop libraries. Mol Immunol 2001;38:313-26.
-
(2001)
Mol Immunol
, vol.38
, pp. 313-326
-
-
Nuttall, S.D.1
Krishnan, U.V.2
Hattarki, M.3
De Gori, R.4
Irving, R.A.5
Hudson, P.J.6
-
8
-
-
0030767656
-
Selection and identification of single domain antibody fragments from camel heavy-chain antibodies
-
Arbabi Ghahroudi M, Desmyter A, Wyns L, Hamers R, Muyldermans S. Selection and identification of single domain antibody fragments from camel heavy-chain antibodies. FEBS Lett 1997;414:521-6.
-
(1997)
FEBS Lett
, vol.414
, pp. 521-526
-
-
Arbabi Ghahroudi, M.1
Desmyter, A.2
Wyns, L.3
Hamers, R.4
Muyldermans, S.5
-
9
-
-
0036182644
-
Single-domain antibody fragments with high conformational stability
-
Dumoulin M, Conrath K, Van Meirhaeghe A, et al. Single-domain antibody fragments with high conformational stability. Protein Sci 2002;11:500-15.
-
(2002)
Protein Sci
, vol.11
, pp. 500-515
-
-
Dumoulin, M.1
Conrath, K.2
Van Meirhaeghe, A.3
-
10
-
-
0031267747
-
Comparison of llama VH sequences from conventional and heavy chain antibodies
-
Vu KB, Ghahroudi MA, Wyns L, Muyldermans S. Comparison of llama VH sequences from conventional and heavy chain antibodies. Mol Immunol 1997;34: 1121-31.
-
(1997)
Mol Immunol
, vol.34
, pp. 1121-1131
-
-
Vu, K.B.1
Ghahroudi, M.A.2
Wyns, L.3
Muyldermans, S.4
-
11
-
-
0037139394
-
Efficient tumor targeting by single-domain antibody fragments of camels
-
Cortez-Retamozo V, Lauwereys M, Hassanzadeh GG, et al. Efficient tumor targeting by single-domain antibody fragments of camels. Int J Cancer 2002;98:456-62.
-
(2002)
Int J Cancer
, vol.98
, pp. 456-462
-
-
Cortez-Retamozo, V.1
Lauwereys, M.2
Hassanzadeh, G.G.3
-
12
-
-
0023619243
-
Antibody directed enzymes revive anti-cancer prodrugs concept
-
Bagshawe KD. Antibody directed enzymes revive anti-cancer prodrugs concept. Br J Cancer, 1987;56:531-2.
-
(1987)
Br J Cancer
, vol.56
, pp. 531-532
-
-
Bagshawe, K.D.1
-
13
-
-
0034812589
-
β-Lactamase inhibitors derived from single-domain antibody fragments elicited in the Camelidae
-
Conrath KE, Lauwereys M, Galleni M, et al. β-Lactamase inhibitors derived from single-domain antibody fragments elicited in the Camelidae. Antimicrob Agents Chemother 2001;45:2807-12.
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 2807-2812
-
-
Conrath, K.E.1
Lauwereys, M.2
Galleni, M.3
-
14
-
-
0024292736
-
Assembly of a functional immunoglobulin Fv fragment in Escherichia coli
-
Skerra A, Pluckthun A. Assembly of a functional immunoglobulin Fv fragment in Escherichia coli. Science (Wash DC) 1988;240:1038-41.
-
(1988)
Science (Wash DC)
, vol.240
, pp. 1038-1041
-
-
Skerra, A.1
Pluckthun, A.2
-
15
-
-
0023134051
-
Common mechanism of ampC β-lactamase induction in enterobacteria: Regulation of the cloned Enterobacter cloacae P99 β-lactamase gene
-
Lindberg F, Normark S. Common mechanism of ampC β-lactamase induction in enterobacteria: regulation of the cloned Enterobacter cloacae P99 β-lactamase gene. J Bacteriol 1987;169:758-63.
-
(1987)
J Bacteriol
, vol.169
, pp. 758-763
-
-
Lindberg, F.1
Normark, S.2
-
17
-
-
0035831483
-
Camel single-domain antibodies as modular building units in bispecific and bivalent antibody constructs
-
Els Conrath K, Lauwereys M, Wyns L, Muyldermans S. Camel single-domain antibodies as modular building units in bispecific and bivalent antibody constructs. J Biol Chem 2001;276:7346-50.
-
(2001)
J Biol Chem
, vol.276
, pp. 7346-7350
-
-
Els Conrath, K.1
Lauwereys, M.2
Wyns, L.3
Muyldermans, S.4
-
18
-
-
0023239268
-
Automated analysis of enzyme inactivation phenomena. Application to β-lactamases and DD-peptidases
-
De Meester F, Joris B, Reckinger G, Bellefroid-Bourguignon C, Frere JM, Waley SG. Automated analysis of enzyme inactivation phenomena. Application to β-lactamases and DD-peptidases. Biochem Pharmacol 1987;36:2393-403.
-
(1987)
Biochem Pharmacol
, vol.36
, pp. 2393-2403
-
-
De Meester, F.1
Joris, B.2
Reckinger, G.3
Bellefroid-Bourguignon, C.4
Frere, J.M.5
Waley, S.G.6
-
19
-
-
0026826545
-
Monoclonal antibody-beta-lactamase conjugates for the activation of a cephalosporin mustard prodrug
-
Svensson HP, Kadow JF, Vrudhula VM, Wallace PM, Senter PD. Monoclonal antibody-beta-lactamase conjugates for the activation of a cephalosporin mustard prodrug. Bioconj Chem 1992;3:176-81.
-
(1992)
Bioconj Chem
, vol.3
, pp. 176-181
-
-
Svensson, H.P.1
Kadow, J.F.2
Vrudhula, V.M.3
Wallace, P.M.4
Senter, P.D.5
-
20
-
-
0035980983
-
Selective activation of anticancer prodrugs by monoclonal antibody-enzyme conjugates
-
Senter PD, Springer CJ. Selective activation of anticancer prodrugs by monoclonal antibody-enzyme conjugates. Adv Drug Deliv Rev 2001;53:247-64.
-
(2001)
Adv Drug Deliv Rev
, vol.53
, pp. 247-264
-
-
Senter, P.D.1
Springer, C.J.2
-
21
-
-
0024287069
-
Sequence and comparative analysis of three Enterobacter cloacae ampC β-lactamase genes and their products
-
Galleni M, Lindberg F, Normark S, et al. Sequence and comparative analysis of three Enterobacter cloacae ampC β-lactamase genes and their products. Biochem J 1988; 250:753-60.
-
(1988)
Biochem J
, vol.250
, pp. 753-760
-
-
Galleni, M.1
Lindberg, F.2
Normark, S.3
-
22
-
-
0034329287
-
Immunoglobulin VH domains and beyond: Design and selection of single-domain binding and targeting reagents
-
Nuttall SD, Irving RA, Hudson PJ. Immunoglobulin VH domains and beyond: design and selection of single-domain binding and targeting reagents. Curr Pharm Biotechnol 2000;1:253-63.
-
(2000)
Curr Pharm Biotechnol
, vol.1
, pp. 253-263
-
-
Nuttall, S.D.1
Irving, R.A.2
Hudson, P.J.3
-
23
-
-
0030822252
-
Scaffolds for engineering novel binding sites in proteins
-
Nygren PA, Uhlen M. Scaffolds for engineering novel binding sites in proteins. Curr Opin Struct Biol 1997;7:463-9.
-
(1997)
Curr Opin Struct Biol
, vol.7
, pp. 463-469
-
-
Nygren, P.A.1
Uhlen, M.2
-
24
-
-
0035816720
-
Optimal design features of camelized human single-domain antibody libraries
-
Tanha J, Xu P, Chen Z, et al. Optimal design features of camelized human single-domain antibody libraries. J Biol Chem 2001;276:24774-80.
-
(2001)
J Biol Chem
, vol.276
, pp. 24774-24780
-
-
Tanha, J.1
Xu, P.2
Chen, Z.3
-
25
-
-
0029764444
-
Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme
-
Desmyter A, Transue TR, Ghahroudi MA, et al. Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme. Nat Struct Biol 1996;3:803-11.
-
(1996)
Nat Struct Biol
, vol.3
, pp. 803-811
-
-
Desmyter, A.1
Transue, T.R.2
Ghahroudi, M.A.3
-
26
-
-
0029764698
-
The crystal structure of a llama heavy chain variable domain
-
Spinelli S, Frenken L, Bourgeois D, et al. The crystal structure of a llama heavy chain variable domain. Nat Struct Biol 1996;3:752-7.
-
(1996)
Nat Struct Biol
, vol.3
, pp. 752-757
-
-
Spinelli, S.1
Frenken, L.2
Bourgeois, D.3
-
27
-
-
0033103453
-
Unique single-domain antigen binding fragments derived from naturally occurring camel heavy-chain antibodies
-
Muyldermans S, Lauwereys M. Unique single-domain antigen binding fragments derived from naturally occurring camel heavy-chain antibodies. J Mol Recognit 1999;12:131-40.
-
(1999)
J Mol Recognit
, vol.12
, pp. 131-140
-
-
Muyldermans, S.1
Lauwereys, M.2
-
28
-
-
0028078866
-
Phage libraries for generation of clinically useful antibodies
-
Chester KA, Begent RH, Robson L, et al. Phage libraries for generation of clinically useful antibodies. Lancet 1994;343:455-6.
-
(1994)
Lancet
, vol.343
, pp. 455-456
-
-
Chester, K.A.1
Begent, R.H.2
Robson, L.3
-
29
-
-
0030250722
-
Generation of a panel of related human scFv antibodies with high affinities for human CEA
-
Osbourn JK, Field A, Wilton J, et al. Generation of a panel of related human scFv antibodies with high affinities for human CEA. Immunotechnology 1996;2:181-96.
-
(1996)
Immunotechnology
, vol.2
, pp. 181-196
-
-
Osbourn, J.K.1
Field, A.2
Wilton, J.3
-
30
-
-
0036466876
-
Enhancement of colorectal tumor targeting using a novel biparatopic monoclonal antibody against carcinoembryonic antigen in experimental radioimmunoguided surgery
-
Kim JC, Roh SA, Koo KH, et al. Enhancement of colorectal tumor targeting using a novel biparatopic monoclonal antibody against carcinoembryonic antigen in experimental radioimmunoguided surgery. Int J Cancer 2002;97:542-7.
-
(2002)
Int J Cancer
, vol.97
, pp. 542-547
-
-
Kim, J.C.1
Roh, S.A.2
Koo, K.H.3
-
31
-
-
0029746203
-
Single antibody domains as small recognition units: Design and in vitro antigen selection of camelized, human VH domains with improved protein stability
-
Davies J, Riechmann L. Single antibody domains as small recognition units: design and in vitro antigen selection of camelized, human VH domains with improved protein stability. Protein Eng 1996;9:531-7.
-
(1996)
Protein Eng
, vol.9
, pp. 531-537
-
-
Davies, J.1
Riechmann, L.2
-
32
-
-
0034636843
-
Antiferritin single-chain Fv fragment is a functional protein with properties of a partially structured state: Comparison with the completely folded V(L) domain
-
Martsev SP, Chumanevich AA, Vlasov AP, et al. Antiferritin single-chain Fv fragment is a functional protein with properties of a partially structured state: comparison with the completely folded V(L) domain. Biochemistry 2000;39:8047-57.
-
(2000)
Biochemistry
, vol.39
, pp. 8047-8057
-
-
Martsev, S.P.1
Chumanevich, A.A.2
Vlasov, A.P.3
-
33
-
-
0032532015
-
Comparisons of the ability of human IgG3 hinge mutants, IgM, IgE, and IgA2, to form small immune complexes: A role for flexibility and geometry
-
Roux KH, Strelets L, Brekke OH, Sandlie I, Michaelsen TE. Comparisons of the ability of human IgG3 hinge mutants, IgM, IgE, and IgA2, to form small immune complexes: a role for flexibility and geometry. J Immunol 1998;161:4083-90.
-
(1998)
J Immunol
, vol.161
, pp. 4083-4090
-
-
Roux, K.H.1
Strelets, L.2
Brekke, O.H.3
Sandlie, I.4
Michaelsen, T.E.5
-
34
-
-
12944288238
-
Antibody-directed enzyme prodrug therapy: Efficacy and mechanism of action in colorectal carcinoma
-
Napier MP, Sharma SK, Springer CJ, et al. Antibody-directed enzyme prodrug therapy: efficacy and mechanism of action in colorectal carcinoma. Clin Cancer Res 2000;6:765-72.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 765-772
-
-
Napier, M.P.1
Sharma, S.K.2
Springer, C.J.3
|