Structural motif-based homology modeling of CYP27A1 and site-directed mutational analyses affecting vitamin D hydroxylation

Biophysical Journal

Volumn 90, Issue 10, 2006, Pages 3389-3409

  Prosser, David E ^a   Guo, YuDing ^a   Jia, Zongchao ^a   Jones, Glenville ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALFACALCIDOL; COLECALCIFEROL; CYTOCHROME P450; CYTOCHROME P450 27A1; HEME; UNCLASSIFIED DRUG; VITAMIN D;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL STRAIN COS1; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME STRUCTURE; HYDROGEN BOND; HYDROXYLATION; MAMMAL; MODEL; MOLECULAR INTERACTION; MUTATION; MUTATIONAL ANALYSIS; NONHUMAN; PROKARYOTE; SITE DIRECTED MUTAGENESIS; VITAMIN METABOLISM;

ANIMALIA; MAMMALIA; PROKARYOTA;

EID: 33646167609     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.105.069369     Document Type: Article

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