Molecular modelling of steroidogenic cytochromes P450 from families CYP11, CYP17, CYP19 and CYP21 based on the CYP102 crystal structure

Journal of Steroid Biochemistry and Molecular Biology

Volumn 66, Issue 4, 1998, Pages 217-233

  Lewis, David F V ^a   Lee Robichaud, Peter ^b  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; HUMAN; HUMAN CELL; MOLECULAR MODEL; NONHUMAN; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; AROMATASE; BACTERIAL PROTEINS; BINDING SITES; CATTLE; COMPUTER GRAPHICS; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; HORMONES; HUMANS; HYDROGEN BONDING; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; STEROID 21-HYDROXYLASE; STEROIDS; THERMODYNAMICS;

ANIMALIA; BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 0031709649     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(98)00032-6     Document Type: Article

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