Microsomal P450s use specific proline-rich sequences for efficient folding, but not for maintenance of the folded structure

Journal of Biochemistry

Volumn 129, Issue 2, 2001, Pages 259-269

  Kusano, Kazutomi ^a,d   Sakaguchi, Masao ^b,c   Kagawa, Norio ^a   Waterman, Michael R ^a   Omura, Tsuneo ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KYUSHU UNIVERSITY   (Japan)

^c Drug Safety and Disposition Research Laboratories ^*

^d EISAI CO LTD   (Japan)

Author keywords

Escherichia coli; Folding; Microsomal P450; Proline rich sequence

Indexed keywords

BLOOD CLOTTING FACTOR 10A; CYTOCHROME C2; CYTOCHROME P450; CYTOCHROME P450 2C11; PROLINE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; EUKARYOTIC CELL; MULTIGENE FAMILY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS;

ANIMALIA; ESCHERICHIA COLI; EUKARYOTA; INSECTA;

EID: 0035110289     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a002853     Document Type: Article

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