Apoptotic death concurrent with CD3 stimulation in primary human CD8 + T lymphocytes: A role for endogenous granzyme B

Journal of Immunology

Volumn 176, Issue 7, 2006, Pages 3966-3977

  Laforge, Mireille ^a   Bidère, Nicolas ^a   Carmona, Sylvie ^a   Devocelle, Aurore ^a   Charpentier, Bernard ^a   Senik, Anna ^a  

^a HÔPITAL PAUL BROUSSE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; FAS ANTIGEN; GRANZYME A; GRANZYME B; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; INTERLEUKIN 2; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD3; PROCASPASE 3; PROTEIN BID; PROTEINASE; PROTEINASE INHIBITOR; PROTEINASE INHIBITOR 9; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG; ANTIBODY; CASP3 PROTEIN, HUMAN; CASPASE; CASPASE 3; CATHEPSIN; CELL EXTRACT; GRANZYME; GZMB PROTEIN, HUMAN; MEMBRANE PROTEIN; PERFORIN; PORE FORMING CYTOTOXIC PROTEIN; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; SMALL INTERFERING RNA;

ANTIGEN RECOGNITION; APOPTOSIS; ARTICLE; CD8+ T LYMPHOCYTE; CELL GRANULE; CONTROLLED STUDY; CYTOLYSIS; CYTOSOL; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENE SILENCING; GRB GENE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IMMUNOSTIMULATION; MONOCYTE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; CD4+ T LYMPHOCYTE; CELL CULTURE; CONFOCAL MICROSCOPY; CYTOLOGY; DOWN REGULATION; DRUG EFFECT; GENETICS; IMMUNOLOGY; METABOLISM; MITOCHONDRION; PROTEIN BINDING; PROTEIN TRANSPORT;

ANTIBODIES; ANTIGENS, CD3; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASE 3; CASPASES; CATHEPSINS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL EXTRACTS; CELLS, CULTURED; CYTOSOL; DOWN-REGULATION; GRANZYMES; HUMANS; MEMBRANE GLYCOPROTEINS; MICROSCOPY, CONFOCAL; MITOCHONDRIA; PORE FORMING CYTOTOXIC PROTEINS; PROTEIN BINDING; PROTEIN TRANSPORT; RNA, SMALL INTERFERING; SERINE ENDOPEPTIDASES; SERPINS;

EID: 33646070316     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.7.3966     Document Type: Article

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