A novel cytotoxicity assay to evaluate antigen-specific CTL responses using a colorimetric substrate for Granzyme B

Journal of Immunological Methods

Volumn 276, Issue 1-2, 2003, Pages 89-101

  Ewen, Catherine ^a   Kane, Kevin P ^a   Shostak, Irene ^a   Griebel, Philip J ^b   Bertram, Edward M ^c   Watts, Tania H ^c   Bleackley, R C ^a   McElhaney, Janet E ^d  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

Author keywords

51Cr release; Cytotoxic T lymphocytes (CTLs); Cytotoxicity; GrB activity

Indexed keywords

ACETYLISOLEUCYLGLUTAMYLTHREONYLASPARTIC ACID 4 NITROANILIDE; GRANZYME B; PEPTIDE; TETRAMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN SPECIFICITY; ARTICLE; BIOASSAY; CELL STIMULATION; CELLULAR IMMUNITY; CHROMIUM 51 RELEASE; COLORIMETRY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SUBSTRATE; EXOCYTOSIS; FEMALE; HUMAN; HUMAN CELL; HYDROLYSIS; INFLUENZA; LEUKEMIA CELL LINE; LEUKOCYTE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; TARGET CELL DESTRUCTION;

MURINAE;

EID: 0242417478     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(03)00073-5     Document Type: Article

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