Mutations that reduce aggregation of the alzheimer℉s Aβ42 peptide: An unbiased search for the sequence determinants of Aβ amyloidogenesis

Journal of Molecular Biology

Volumn 319, Issue 5, 2002, Pages 1279-1290

  Wurth, Christine ^a   Guimard, Nathalie K ^a   Hecht, Michael H ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Amyloid peptide variant; Amyloidogenesis; Green fluorescent protein; Protein aggregation

Indexed keywords

AMYLOID BETA PROTEIN; GREEN FLUORESCENT PROTEIN;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BASE PAIRING; CONTROLLED STUDY; ESCHERICHIA COLI; FLUORESCENCE; GENE CLUSTER; GENETIC SCREENING; HYDROPHOBICITY; MUTAGENESIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN SECONDARY STRUCTURE; SOLUBILITY;

EID: 0036308719     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00399-6     Document Type: Article

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