-
1
-
-
0023838532
-
Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease
-
Abraham C.R., Selkoe D.J., Potter H. Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease. Cell. 52:1988;487-501
-
(1988)
Cell
, vol.52
, pp. 487-501
-
-
Abraham, C.R.1
Selkoe, D.J.2
Potter, H.3
-
2
-
-
0034612175
-
Inflammation and Alzheimer's disease
-
Akiyama H., Barger S., Barnum S., Bradt B., Bauer J., Cole G.M., et al. Inflammation and Alzheimer's disease. Neurobiol. Aging. 21:2000;383-421
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 383-421
-
-
Akiyama, H.1
Barger, S.2
Barnum, S.3
Bradt, B.4
Bauer, J.5
Cole, G.M.6
-
3
-
-
0031971420
-
Behavioural, physiological and morphological analysis of a line of apolipoprotein e knockout mouse
-
Anderson R., Barnes J.C., Bliss T.V., Cain D.P., Cambon K., Davies H.A., et al. Behavioural, physiological and morphological analysis of a line of apolipoprotein E knockout mouse. Neuroscience. 85:1998;93-110
-
(1998)
Neuroscience
, vol.85
, pp. 93-110
-
-
Anderson, R.1
Barnes, J.C.2
Bliss, T.V.3
Cain, D.P.4
Cambon, K.5
Davies, H.A.6
-
4
-
-
0030877056
-
Absence of central cholinergic deficits in ApoE knockout mice
-
Anderson R., Higgins G.A. Absence of central cholinergic deficits in ApoE knockout mice. Psychopharmacology (Berl). 132:1997;135-144
-
(1997)
Psychopharmacology (Berl)
, vol.132
, pp. 135-144
-
-
Anderson, R.1
Higgins, G.A.2
-
5
-
-
0035689651
-
Behavioral assessment of Alzheimer's transgenic mice following long-term Abeta vaccination: Task specificity and correlations between Abeta deposition and spatial memory
-
Arendash G.W., Gordon M.N., Diamond D.M., Austin L.A., Hatcher J.M., Jantzen P., et al. Behavioral assessment of Alzheimer's transgenic mice following long-term Abeta vaccination: task specificity and correlations between Abeta deposition and spatial memory. DNA Cell Biol. 20:2001;737-744
-
(2001)
DNA Cell Biol.
, vol.20
, pp. 737-744
-
-
Arendash, G.W.1
Gordon, M.N.2
Diamond, D.M.3
Austin, L.A.4
Hatcher, J.M.5
Jantzen, P.6
-
6
-
-
0035830686
-
Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes
-
Arendash G.W., King D.L., Gordon M.N., Morgan D., Hatcher J.M., Hope C.E., et al. Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes. Brain Res. 891:2001;42-53
-
(2001)
Brain Res.
, vol.891
, pp. 42-53
-
-
Arendash, G.W.1
King, D.L.2
Gordon, M.N.3
Morgan, D.4
Hatcher, J.M.5
Hope, C.E.6
-
7
-
-
0033593027
-
Apolipoprotein e is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease
-
Bales K.R., Verina T., Cummins D.J., Du Y., Dodel R.C., Saura J., et al. Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. USA. 96:1999;15233-15238
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 15233-15238
-
-
Bales, K.R.1
Verina, T.2
Cummins, D.J.3
Du, Y.4
Dodel, R.C.5
Saura, J.6
-
8
-
-
0031278270
-
Lack of apolipoprotein e dramatically reduces amyloid beta-peptide deposition
-
Bales K.R., Verina T., Dodel R.C., Du Y., Altstiel L., Bender M., et al. Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition. Nat. Genet. 17:1997;263-264
-
(1997)
Nat. Genet
, vol.17
, pp. 263-264
-
-
Bales, K.R.1
Verina, T.2
Dodel, R.C.3
Du, Y.4
Altstiel, L.5
Bender, M.6
-
9
-
-
0037115049
-
Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein e depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation
-
Buttini M., Yu G.Q., Shockley K., Huang Y., Jones B., Masliah E., et al. Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation. J. Neurosci. 22:2002;10539-10548
-
(2002)
J. Neurosci.
, vol.22
, pp. 10539-10548
-
-
Buttini, M.1
Yu, G.Q.2
Shockley, K.3
Huang, Y.4
Jones, B.5
Masliah, E.6
-
10
-
-
0026448114
-
Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor
-
Buxbaum J.D., Oishi M., Chen H.I., Pinkas-Kramarski R., Jaffe E.A., Gandy S.E., et al. Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor. Proc. Natl. Acad. Sci. USA. 89:1992;10075-10078
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10075-10078
-
-
Buxbaum, J.D.1
Oishi, M.2
Chen, H.I.3
Pinkas-Kramarski, R.4
Jaffe, E.A.5
Gandy, S.E.6
-
11
-
-
0037063728
-
Apolipoprotein e knockout mice display procedural deficits in the Morris Water Maze: Analysis of learning strategies in three versions of the task
-
Champagne D., Dupuy J.B., Rochford J., Poirier J. Apolipoprotein E knockout mice display procedural deficits in the Morris Water Maze: analysis of learning strategies in three versions of the task. Neuroscience. 114:2002;641-654
-
(2002)
Neuroscience
, vol.114
, pp. 641-654
-
-
Champagne, D.1
Dupuy, J.B.2
Rochford, J.3
Poirier, J.4
-
12
-
-
0034700480
-
A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease
-
Chen G., Chen K.S., Knox J., Inglis J., Bernard A., Martin S.J., et al. A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease. Nature. 408:2000;975-979
-
(2000)
Nature
, vol.408
, pp. 975-979
-
-
Chen, G.1
Chen, K.S.2
Knox, J.3
Inglis, J.4
Bernard, A.5
Martin, S.J.6
-
13
-
-
0027194791
-
Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder E.H., Saunders A.M., Strittmatter W.J., Schmechel D.E., Gaskell P.C., Small G.W., et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science. 261:1993;921-923
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
-
14
-
-
0028889206
-
Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1
-
Das S., Potter H. Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1. Neuron. 14:1995;447-456
-
(1995)
Neuron
, vol.14
, pp. 447-456
-
-
Das, S.1
Potter, H.2
-
15
-
-
0037231452
-
Plasma and cerebrospinal fluid alpha1-antichymotrypsin levels in Alzheimer's disease: Correlation with cognitive impairment
-
DeKosky S.T., Ikonomovic M.D., Wang X., Farlow M., Wisniewski S., Lopez O.L., et al. Plasma and cerebrospinal fluid alpha1-antichymotrypsin levels in Alzheimer's disease: correlation with cognitive impairment. Ann. Neurol. 53:2003;81-90
-
(2003)
Ann. Neurol.
, vol.53
, pp. 81-90
-
-
Dekosky, S.T.1
Ikonomovic, M.D.2
Wang, X.3
Farlow, M.4
Wisniewski, S.5
Lopez, O.L.6
-
16
-
-
0036678856
-
Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease
-
DeMattos R.B., O'Dell M.A., Parsadanian M., Taylor J.W., Harmony J.A., Bales K.R., et al. Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. USA. 99:2002;10843-10848
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10843-10848
-
-
Demattos, R.B.1
O'Dell, M.A.2
Parsadanian, M.3
Taylor, J.W.4
Harmony, J.A.5
Bales, K.R.6
-
17
-
-
0036240395
-
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model
-
Dodart J.C., Bales K.R., Gannon K.S., Greene S.J., DeMattos R.B., Mathis C., et al. Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model. Nat Neurosci. 5:2002;452-457
-
(2002)
Nat Neurosci.
, vol.5
, pp. 452-457
-
-
Dodart, J.C.1
Bales, K.R.2
Gannon, K.S.3
Greene, S.J.4
Demattos, R.B.5
Mathis, C.6
-
18
-
-
0037111263
-
Apolipoprotein e alters the processing of the beta-amyloid precursor protein in APP(V717F) transgenic mice
-
Dodart J.C., Bales K.R., Johnstone E.M., Little S.P., Paul S.M. Apolipoprotein E alters the processing of the beta-amyloid precursor protein in APP(V717F) transgenic mice. Brain Res. 955:2002;191-199
-
(2002)
Brain Res.
, vol.955
, pp. 191-199
-
-
Dodart, J.C.1
Bales, K.R.2
Johnstone, E.M.3
Little, S.P.4
Paul, S.M.5
-
19
-
-
0033999810
-
Behavioral deficits in APP(V717F) transgenic mice deficient for the apolipoprotein e gene
-
Dodart J.C., Mathis C., Bales K.R., Paul S.M., Ungerer A. Behavioral deficits in APP(V717F) transgenic mice deficient for the apolipoprotein E gene. Neuroreport. 11:2000;603-607
-
(2000)
Neuroreport
, vol.11
, pp. 603-607
-
-
Dodart, J.C.1
Mathis, C.2
Bales, K.R.3
Paul, S.M.4
Ungerer, A.5
-
20
-
-
16044366039
-
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1
-
Duff K., Eckman C., Zehr C., Yu X., Prada C.M., Perez-tur J., et al. Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1. Nature. 383:1996;710-713
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.M.5
Perez-Tur, J.6
-
21
-
-
0036233168
-
Human and murine ApoE markedly alters a beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease
-
Fagan A.M., Watson M., Parsadanian M., Bales K.R., Paul S.M., Holtzman D.M. Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease. Neurobiol. Dis. 9:2002;305-318
-
(2002)
Neurobiol. Dis.
, vol.9
, pp. 305-318
-
-
Fagan, A.M.1
Watson, M.2
Parsadanian, M.3
Bales, K.R.4
Paul, S.M.5
Holtzman, D.M.6
-
22
-
-
0026452028
-
Expression of amyloid precursor protein mRNAs in endothelial, neuronal and glial cells: Modulation by interleukin-1
-
Forloni G., Demicheli F., Giorgi S., Bendotti C., Angeretti N. Expression of amyloid precursor protein mRNAs in endothelial, neuronal and glial cells: modulation by interleukin-1. Brain Res. Mol. Brain Res. 16:1992;128-134
-
(1992)
Brain Res. Mol. Brain Res.
, vol.16
, pp. 128-134
-
-
Forloni, G.1
Demicheli, F.2
Giorgi, S.3
Bendotti, C.4
Angeretti, N.5
-
23
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
-
Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C., et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature. 373:1995;523-527
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
-
24
-
-
0005775566
-
Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells
-
Goldgaber D., Harris H.W., Hla T., Maciag T., Donnelly R.J., Jacobsen J.S., et al. Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells. Proc. Natl. Acad. Sci. USA. 86:1989;7606-7610
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 7606-7610
-
-
Goldgaber, D.1
Harris, H.W.2
Hla, T.3
MacIag, T.4
Donnelly, R.J.5
Jacobsen, J.S.6
-
25
-
-
0034988318
-
Correlation between cognitive deficits and Abeta deposits in transgenic APP+PS1 mice
-
Gordon M.N., King D.L., Diamond D.M., Jantzen P.T., Boyett K.V., Hope C.E., et al. Correlation between cognitive deficits and Abeta deposits in transgenic APP+PS1 mice. Neurobiol. Aging. 22:2001;377-385
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 377-385
-
-
Gordon, M.N.1
King, D.L.2
Diamond, D.M.3
Jantzen, P.T.4
Boyett, K.V.5
Hope, C.E.6
-
26
-
-
0034515761
-
Pathways to primary neurodegenerative disease
-
Hardy J. Pathways to primary neurodegenerative disease. Ann. NY Acad. Sci. 924:2000;29-34
-
(2000)
Ann. NY Acad. Sci.
, vol.924
, pp. 29-34
-
-
Hardy, J.1
-
27
-
-
0030614627
-
Observation of metastable Abeta amyloid protofibrils by atomic force microscopy
-
Harper J.D., Wong S.S., Lieber C.M., Lansbury P.T. Observation of metastable Abeta amyloid protofibrils by atomic force microscopy. Chem. Biol. 4:1997;119-125
-
(1997)
Chem. Biol.
, vol.4
, pp. 119-125
-
-
Harper, J.D.1
Wong, S.S.2
Lieber, C.M.3
Lansbury, P.T.4
-
28
-
-
4243215848
-
Apolipoprotein e isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease
-
Holtzman D.M., Bales K.R., Tenkova T., Fagan A.M., Parsadanian M., Sartorius L.J., et al. Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. USA. 97:2000;2892-2897
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2892-2897
-
-
Holtzman, D.M.1
Bales, K.R.2
Tenkova, T.3
Fagan, A.M.4
Parsadanian, M.5
Sartorius, L.J.6
-
29
-
-
0032561313
-
Alzheimer's peptide Abeta1-42 binds to two beta-sheets of alpha1-antichymotrypsin and transforms it from inhibitor to substrate
-
Janciauskiene S., Rubin H., Lukacs C.M., Wright H.T. Alzheimer's peptide Abeta1-42 binds to two beta-sheets of alpha1-antichymotrypsin and transforms it from inhibitor to substrate. J. Biol. Chem. 273:1998;28360-28364
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 28360-28364
-
-
Janciauskiene, S.1
Rubin, H.2
Lukacs, C.M.3
Wright, H.T.4
-
31
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
-
Lambert M.P., Barlow A.K., Chromy B.A., Edwards C., Freed R., Liosatos M., et al. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc. Natl. Acad. Sci. USA. 95:1998;6448-6453
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
-
32
-
-
0032146242
-
Increased levels of alpha-1-antichymotrypsin in brains of patients with Alzheimer's disease correlate with activated astrocytes and are affected by APOE 4 genotype
-
Licastro F., Mallory M., Hansen L.A., Masliah E. Increased levels of alpha-1-antichymotrypsin in brains of patients with Alzheimer's disease correlate with activated astrocytes and are affected by APOE 4 genotype. J. Neuroimmunol. 88:1998;105-110
-
(1998)
J. Neuroimmunol.
, vol.88
, pp. 105-110
-
-
Licastro, F.1
Mallory, M.2
Hansen, L.A.3
Masliah, E.4
-
33
-
-
0034254924
-
Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease
-
Lim G.P., Yang F., Chu T., Chen P., Beech W., Teter B., et al. Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease. J. Neurosci. 20:2000;5709-5714
-
(2000)
J. Neurosci.
, vol.20
, pp. 5709-5714
-
-
Lim, G.P.1
Yang, F.2
Chu, T.3
Chen, P.4
Beech, W.5
Teter, B.6
-
34
-
-
0029795311
-
Is the binding of beta-amyloid protein to antichymotrypsin in Alzheimer plaques mediated by a beta-strand insertion?
-
Lukacs C.M., Christianson D.W. Is the binding of beta-amyloid protein to antichymotrypsin in Alzheimer plaques mediated by a beta-strand insertion? Proteins. 25:1996;420-424
-
(1996)
Proteins
, vol.25
, pp. 420-424
-
-
Lukacs, C.M.1
Christianson, D.W.2
-
35
-
-
0000448998
-
Alzheimer a beta neurotoxicity: Promotion by antichymotrypsin, ApoE4 inhibition by a beta-related peptides
-
Ma J., Brewer H.B. Jr., Potter H. Alzheimer A beta neurotoxicity: promotion by antichymotrypsin, ApoE4 inhibition by A beta-related peptides. Neurobiol. Aging. 17:1996;773-780
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 773-780
-
-
Ma, J.1
Brewer Jr., H.B.2
Potter, H.3
-
36
-
-
0028173205
-
Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein e promote assembly of Alzheimer beta-protein into filaments
-
Ma J., Yee A., Brewer H.B. Jr., Das S., Potter H. Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer beta-protein into filaments. Nature. 372:1994;92-94
-
(1994)
Nature
, vol.372
, pp. 92-94
-
-
Ma, J.1
Yee, A.2
Brewer Jr., H.B.3
Das, S.4
Potter, H.5
-
38
-
-
84984755327
-
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
Morgan D., Diamond D.M., Gottschall P.E., Ugen K.E., Dickey C., Hardy J., et al. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature. 408:2000;982-985
-
(2000)
Nature
, vol.408
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
Ugen, K.E.4
Dickey, C.5
Hardy, J.6
-
39
-
-
0019957779
-
Place navigation impaired in rats with hippocampal lesions
-
Morris R.G., Garrud P., Rawlins J.N., O'Keefe J. Place navigation impaired in rats with hippocampal lesions. Nature. 297:1982;681-683
-
(1982)
Nature
, vol.297
, pp. 681-683
-
-
Morris, R.G.1
Garrud, P.2
Rawlins, J.N.3
O'Keefe, J.4
-
40
-
-
0034045148
-
Interleukin-1 and the immunogenetics of Alzheimer disease
-
Mrak R.E., Griffin W.S. Interleukin-1 and the immunogenetics of Alzheimer disease. J. Neuropathol. Exp. Neurol. 59:2000;471-476
-
(2000)
J. Neuropathol. Exp. Neurol.
, vol.59
, pp. 471-476
-
-
Mrak, R.E.1
Griffin, W.S.2
-
41
-
-
0033635193
-
Astroglial expression of human alpha(1)-antichymotrypsin enhances alzheimer-like pathology in amyloid protein precursor transgenic mice
-
Mucke L., Yu G.Q., McConlogue L., Rockenstein E.M., Abraham C.R., Masliah E. Astroglial expression of human alpha(1)-antichymotrypsin enhances alzheimer-like pathology in amyloid protein precursor transgenic mice. Am. J. Pathol. 157:2000;2003-2010
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 2003-2010
-
-
Mucke, L.1
Yu, G.Q.2
McConlogue, L.3
Rockenstein, E.M.4
Abraham, C.R.5
Masliah, E.6
-
42
-
-
0037104754
-
Compromised hemodynamic response in amyloid precursor protein transgenic mice
-
Mueggler T., Sturchler-Pierrat C., Baumann D., Rausch M., Staufenbiel M., Rudin M. Compromised hemodynamic response in amyloid precursor protein transgenic mice. J. Neurosci. 22:2002;7218-7224
-
(2002)
J. Neurosci.
, vol.22
, pp. 7218-7224
-
-
Mueggler, T.1
Sturchler-Pierrat, C.2
Baumann, D.3
Rausch, M.4
Staufenbiel, M.5
Rudin, M.6
-
43
-
-
0025971426
-
Apolipoprotein e immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease
-
Namba Y., Tomonaga M., Kawasaki H., Otomo E., Ikeda K. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res. 541:1991;163-166
-
(1991)
Brain Res.
, vol.541
, pp. 163-166
-
-
Namba, Y.1
Tomonaga, M.2
Kawasaki, H.3
Otomo, E.4
Ikeda, K.5
-
44
-
-
0002235557
-
The essential role of inflammation and induced gene expression in the pathogenic pathway of Alzheimer's disease
-
Nilsson L., Rogers J., Potter H. The essential role of inflammation and induced gene expression in the pathogenic pathway of Alzheimer's disease. Front Biosci. 3:1998;d436-d446
-
(1998)
Front Biosci.
, vol.3
-
-
Nilsson, L.1
Rogers, J.2
Potter, H.3
-
45
-
-
0035282790
-
Alpha-1-antichymotrypsin promotes beta-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease
-
Nilsson L.N., Bales K.R., DiCarlo G., Gordon M.N., Morgan D., Paul S.M., et al. Alpha-1-antichymotrypsin promotes beta-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease. J. Neurosci. 21:2001;1444-1451
-
(2001)
J. Neurosci.
, vol.21
, pp. 1444-1451
-
-
Nilsson, L.N.1
Bales, K.R.2
Dicarlo, G.3
Gordon, M.N.4
Morgan, D.5
Paul, S.M.6
-
46
-
-
0034741128
-
Effect of cytokines, dexamethasone and the A/T-signal peptide polymorphism on the expression of alpha(1)-antichymotrypsin in astrocytes: Significance for Alzheimer's disease
-
Nilsson L.N., Das S., Potter H. Effect of cytokines, dexamethasone and the A/T-signal peptide polymorphism on the expression of alpha(1)- antichymotrypsin in astrocytes: significance for Alzheimer's disease. Neurochem. Int. 39:2001;361-370
-
(2001)
Neurochem. Int.
, vol.39
, pp. 361-370
-
-
Nilsson, L.N.1
Das, S.2
Potter, H.3
-
47
-
-
0028828044
-
Clusterin (apoJ) alters the aggregation of amyloid beta-peptide (A beta 1-42) and forms slowly sedimenting a beta complexes that cause oxidative stress
-
Oda T., Wals P., Osterburg H.H., Johnson S.A., Pasinetti G.M., Morgan T.E., et al. Clusterin (apoJ) alters the aggregation of amyloid beta-peptide (A beta 1-42) and forms slowly sedimenting A beta complexes that cause oxidative stress. Exp. Neurol. 136:1995;22-31
-
(1995)
Exp. Neurol.
, vol.136
, pp. 22-31
-
-
Oda, T.1
Wals, P.2
Osterburg, H.H.3
Johnson, S.A.4
Pasinetti, G.M.5
Morgan, T.E.6
-
48
-
-
0030740829
-
Assessment of learning by the Morris water task and fear conditioning in inbred mouse strains and F1 hybrids: Implications of genetic background for single gene mutations and quantitative trait loci analyses
-
Owen E.H., Logue S.F., Rasmussen D.L., Wehner J.M. Assessment of learning by the Morris water task and fear conditioning in inbred mouse strains and F1 hybrids: implications of genetic background for single gene mutations and quantitative trait loci analyses. Neuroscience. 80:1997;1087-1099
-
(1997)
Neuroscience
, vol.80
, pp. 1087-1099
-
-
Owen, E.H.1
Logue, S.F.2
Rasmussen, D.L.3
Wehner, J.M.4
-
49
-
-
0034515763
-
Apolipoprotein e and Alzheimer's disease. a role in amyloid catabolism
-
Poirier J. Apolipoprotein E and Alzheimer's disease. A role in amyloid catabolism. Ann. NY Acad. Sci. 924:2000;81-90
-
(2000)
Ann. NY Acad. Sci.
, vol.924
, pp. 81-90
-
-
Poirier, J.1
-
50
-
-
0002742452
-
The two Alzheimers amyloid components a-antichymotrypsin and b-protein form a stable complex in vitro
-
Iqbal K, McLachlan D, Winblad B, Wisniewski H, editors. New York: John Wiley and Sons Ltd.;
-
Potter H, Abraham CR, Dressler D. The two Alzheimers amyloid components a-antichymotrypsin and b-protein form a stable complex in vitro. In: Iqbal K, McLachlan D, Winblad B, Wisniewski H, editors. Alzheimer's disease basic mechanisms, diagnosis and therapuetic strategies. New York: John Wiley and Sons Ltd.; 1991.
-
(1991)
Alzheimer's Disease Basic Mechanisms, Diagnosis and Therapuetic Strategies
-
-
Potter, H.1
Abraham, C.R.2
Dressler, D.3
-
51
-
-
0035696320
-
The inflammation-induced pathological chaperones ACT and apo-E are necessary catalysts of Alzheimer amyloid formation
-
Potter H., Wefes I.M., Nilsson L.N. The inflammation-induced pathological chaperones ACT and apo-E are necessary catalysts of Alzheimer amyloid formation. Neurobiol. Aging. 22:2001;923-930
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 923-930
-
-
Potter, H.1
Wefes, I.M.2
Nilsson, L.N.3
-
52
-
-
0031921466
-
Mutant genes in familial Alzheimer's disease and transgenic models
-
Price D.L., Sisodia S.S. Mutant genes in familial Alzheimer's disease and transgenic models. Annu. Rev. Neurosci. 21:1998;479-505
-
(1998)
Annu. Rev. Neurosci.
, vol.21
, pp. 479-505
-
-
Price, D.L.1
Sisodia, S.S.2
-
53
-
-
0035726544
-
Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse
-
Qiao X., Cummins D.J., Paul S.M. Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse. Eur. J. Neurosci. 14:2001;474-482
-
(2001)
Eur. J. Neurosci.
, vol.14
, pp. 474-482
-
-
Qiao, X.1
Cummins, D.J.2
Paul, S.M.3
-
54
-
-
0032886820
-
Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains
-
Rogers D.C., Jones D.N., Nelson P.R., Jones C.M., Quilter C.A., Robinson T.L., et al. Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains. Behav. Brain Res. 105:1999;207-217
-
(1999)
Behav. Brain Res.
, vol.105
, pp. 207-217
-
-
Rogers, D.C.1
Jones, D.N.2
Nelson, P.R.3
Jones, C.M.4
Quilter, C.A.5
Robinson, T.L.6
-
55
-
-
0033525735
-
Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences
-
Rogers J.T., Leiter L.M., McPhee J., Cahill C.M., Zhan S.S., Potter H., et al. Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences. J. Biol. Chem. 274:1999;6421-6431
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6421-6431
-
-
Rogers, J.T.1
Leiter, L.M.2
McPhee, J.3
Cahill, C.M.4
Zhan, S.S.5
Potter, H.6
-
56
-
-
0028026587
-
Apolipoprotein e associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3
-
Sanan D.A., Weisgraber K.H., Russell S.J., Mahley R.W., Huang D., Saunders A., et al. Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3. J. Clin. Invest. 94:1994;860-869
-
(1994)
J. Clin. Invest
, vol.94
, pp. 860-869
-
-
Sanan, D.A.1
Weisgraber, K.H.2
Russell, S.J.3
Mahley, R.W.4
Huang, D.5
Saunders, A.6
-
57
-
-
16044373524
-
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner D., Eckman C., Jensen M., Song X., Citron M., Suzuki N., et al. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. 2:1996;864-870
-
(1996)
Nat. Med.
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
-
58
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe D.J. Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 81:2001;741-766
-
(2001)
Physiol. Rev.
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
60
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter W.J., Saunders A.M., Schmechel D., Pericak-Vance M., Enghild J., Salvesen G.S., et al. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. USA. 90:1993;1977-1981
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
-
61
-
-
0028882424
-
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
-
Telling G.C., Scott M., Mastrianni J., Gabizon R., Torchia M., Cohen F.E., et al. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell. 83:1995;79-90
-
(1995)
Cell
, vol.83
, pp. 79-90
-
-
Telling, G.C.1
Scott, M.2
Mastrianni, J.3
Gabizon, R.4
Torchia, M.5
Cohen, F.E.6
-
62
-
-
0035805091
-
Apolipoprotein e deposition and astrogliosis are associated with maturation of beta-amyloid plaques in betaAPPswe transgenic mouse: Implications for the pathogenesis of Alzheimer's disease
-
Terai K., Iwai A., Kawabata S., Sasamata M., Miyata K., Yamaguchi T. Apolipoprotein E deposition and astrogliosis are associated with maturation of beta-amyloid plaques in betaAPPswe transgenic mouse: implications for the pathogenesis of Alzheimer's disease. Brain Res. 900:2001;48-56
-
(2001)
Brain Res.
, vol.900
, pp. 48-56
-
-
Terai, K.1
Iwai, A.2
Kawabata, S.3
Sasamata, M.4
Miyata, K.5
Yamaguchi, T.6
-
63
-
-
0029670094
-
Beta-amyloid-mediated vasoactivity and vascular endothelial damage
-
Thomas T., Thomas G., McLendon C., Sutton T., Mullan M. Beta-amyloid-mediated vasoactivity and vascular endothelial damage. Nature. 380:1996;168-171
-
(1996)
Nature
, vol.380
, pp. 168-171
-
-
Thomas, T.1
Thomas, G.2
McLendon, C.3
Sutton, T.4
Mullan, M.5
-
64
-
-
0032958072
-
Synaptic alterations in apolipoprotein e knockout mice
-
Veinbergs I., Masliah E. Synaptic alterations in apolipoprotein E knockout mice. Neuroscience. 91:1999;401-403
-
(1999)
Neuroscience
, vol.91
, pp. 401-403
-
-
Veinbergs, I.1
Masliah, E.2
-
65
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh D.M., Klyubin I., Fadeeva J.V., Cullen W.K., Anwyl R., Wolfe M.S., et al. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature. 416:2002;535-539
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
-
66
-
-
0030799122
-
Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate
-
Walsh D.M., Lomakin A., Benedek G.B., Condron M.M., Teplow D.B. Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate. J. Biol. Chem. 272:1997;22364-22372
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22364-22372
-
-
Walsh, D.M.1
Lomakin, A.2
Benedek, G.B.3
Condron, M.M.4
Teplow, D.B.5
-
67
-
-
0034609516
-
The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain
-
Walsh D.M., Tseng B.P., Rydel R.E., Podlisny M.B., Selkoe D.J. The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain. Biochemistry. 39:2000;10831-10839
-
(2000)
Biochemistry
, vol.39
, pp. 10831-10839
-
-
Walsh, D.M.1
Tseng, B.P.2
Rydel, R.E.3
Podlisny, M.B.4
Selkoe, D.J.5
-
68
-
-
0037059598
-
Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus
-
Wang H.W., Pasternak J.F., Kuo H., Ristic H., Lambert M.P., Chromy B., et al. Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus. Brain Res. 924:2002;133-140
-
(2002)
Brain Res.
, vol.924
, pp. 133-140
-
-
Wang, H.W.1
Pasternak, J.F.2
Kuo, H.3
Ristic, H.4
Lambert, M.P.5
Chromy, B.6
-
69
-
-
0029758030
-
Relative efficacies of amyloid beta peptide (A beta) binding proteins in a beta aggregation
-
Webster S., Rogers J. Relative efficacies of amyloid beta peptide (A beta) binding proteins in A beta aggregation. J. Neurosci. Res. 46:1996;58-66
-
(1996)
J. Neurosci. Res.
, vol.46
, pp. 58-66
-
-
Webster, S.1
Rogers, J.2
-
70
-
-
0026777222
-
Crystallization, activity assay and preliminary X-ray diffraction analysis of the uncleaved form of the serpin antichymotrypsin
-
Wei A., Rubin H., Cooperman B.S., Schechter N., Christianson D.W. Crystallization, activity assay and preliminary X-ray diffraction analysis of the uncleaved form of the serpin antichymotrypsin. J. Mol. Biol. 226:1992;273-276
-
(1992)
J. Mol. Biol.
, vol.226
, pp. 273-276
-
-
Wei, A.1
Rubin, H.2
Cooperman, B.S.3
Schechter, N.4
Christianson, D.W.5
-
72
-
-
0027970307
-
Acceleration of Alzheimer's fibril formation by apolipoprotein e in vitro
-
Wisniewski T., Castano E.M., Golabek A., Vogel T., Frangione B. Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro. Am. J. Pathol. 145:1994;1030-1035
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 1030-1035
-
-
Wisniewski, T.1
Castano, E.M.2
Golabek, A.3
Vogel, T.4
Frangione, B.5
-
73
-
-
0026542786
-
Apolipoprotein E: A pathological chaperone protein in patients with cerebral and systemic amyloid
-
Wisniewski T., Frangione B. Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid. Neurosci. Lett. 135:1992;235-238
-
(1992)
Neurosci. Lett.
, vol.135
, pp. 235-238
-
-
Wisniewski, T.1
Frangione, B.2
-
74
-
-
0344267650
-
Specific regional transcription of apolipoprotein e in human brain neurons
-
Xu P.T., Gilbert J.R., Qiu H.L., Ervin J., Rothrock-Christian T.R., Hulette C., et al. Specific regional transcription of apolipoprotein E in human brain neurons. Am. J. Pathol. 154:1999;601-611
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 601-611
-
-
Xu, P.T.1
Gilbert, J.R.2
Qiu, H.L.3
Ervin, J.4
Rothrock-Christian, T.R.5
Hulette, C.6
-
75
-
-
0031597684
-
Association of alpha1-antichymotrypsin polymorphism with cerebral amyloid angiopathy
-
Yamada M., Sodeyama N., Itoh Y., Suematsu N., Otomo E., Matsushita M., et al. Association of alpha1-antichymotrypsin polymorphism with cerebral amyloid angiopathy. Ann. Neurol. 44:1998;129-131
-
(1998)
Ann. Neurol.
, vol.44
, pp. 129-131
-
-
Yamada, M.1
Sodeyama, N.2
Itoh, Y.3
Suematsu, N.4
Otomo, E.5
Matsushita, M.6
-
76
-
-
0033603328
-
Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimer's amyloid-beta peptide degradation
-
Yamin R., Malgeri E.G., Sloane J.A., McGraw W.T., Abraham C.R. Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimer's amyloid-beta peptide degradation. J. Biol. Chem. 274:1999;18777-18784
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18777-18784
-
-
Yamin, R.1
Malgeri, E.G.2
Sloane, J.A.3
McGraw, W.T.4
Abraham, C.R.5
|