Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis

European Journal of Immunology

Volumn 27, Issue 12, 1997, Pages 3492-3498

  Medema, Jan Paul ^a   Toes, René E M ^b   Scaffidi, Carsten ^a   Zheng, Timothy S ^c   Flavell, Richard A ^c   Melief, Cornelius J M ^b   Peter, Marcus E ^a   Offringa, Rienk ^b   Krammer, Peter H ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Caspase 8; Cytotoxicity; FLICE; Granzyme B; Perforin

Indexed keywords

CELL ENZYME; GRANZYME B; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PERFORIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENZYME ACTIVATION; ENZYME ACTIVITY; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; CASPASE 8; CASPASE 9; CASPASES; CYSTEINE ENDOPEPTIDASES; GRANZYMES; HELA CELLS; HUMANS; MICE; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0031459164     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830271250     Document Type: Article

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