-
1
-
-
0038748022
-
The Bowman lecture. Towards an understanding of age-related macular disease
-
Bird AC. The Bowman lecture. Towards an understanding of age-related macular disease. Eye. 2003;17:457-466.
-
(2003)
Eye
, vol.17
, pp. 457-466
-
-
Bird, A.C.1
-
2
-
-
0037211158
-
Common eye diseases of elderly people: Identifying and treating causes of vision loss
-
Harvey PT. Common eye diseases of elderly people: identifying and treating causes of vision loss. Gerontology. 2003;49:1-11.
-
(2003)
Gerontology
, vol.49
, pp. 1-11
-
-
Harvey, P.T.1
-
4
-
-
0035078715
-
Risk factors for age-related macular degeneration: Pooled findings from three continents
-
Smith W, Assink J, Klein R, et al. Risk factors for age-related macular degeneration: pooled findings from three continents. Ophthalmology. 2001;108:697-704.
-
(2001)
Ophthalmology
, vol.108
, pp. 697-704
-
-
Smith, W.1
Assink, J.2
Klein, R.3
-
5
-
-
0027946498
-
Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration
-
Eye Disease Case-Control Study Group
-
Seddon JM, Ajani UA, Sperduto RD, et al. Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group. JAMA. 1994;272:1413-1420.
-
(1994)
JAMA
, vol.272
, pp. 1413-1420
-
-
Seddon, J.M.1
Ajani, U.A.2
Sperduto, R.D.3
-
6
-
-
0032521155
-
Glutathione in human plasma: Decline in association with aging, age-related macular degeneration, and diabetes
-
Samiec PS, Drews-Botsch C, et al. Glutathione in human plasma: decline in association with aging, age-related macular degeneration, and diabetes. Free Radic Biol Med. 1998;24:699-704.
-
(1998)
Free Radic Biol Med
, vol.24
, pp. 699-704
-
-
Samiec, P.S.1
Drews-Botsch, C.2
-
7
-
-
0035122024
-
Sunlight and the 5-year incidence of early age-related maculopathy: The beaver dam eye study
-
Cruickshanks KJ, Klein R, Klein BE, Nondahl DM. Sunlight and the 5-year incidence of early age-related maculopathy: the beaver dam eye study. Arch Ophthalmol. 2001;119:246-250.
-
(2001)
Arch Ophthalmol
, vol.119
, pp. 246-250
-
-
Cruickshanks, K.J.1
Klein, R.2
Klein, B.E.3
Nondahl, D.M.4
-
8
-
-
0034800655
-
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
-
Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol. 2001;119:1417-1436.
-
(2001)
Arch Ophthalmol
, vol.119
, pp. 1417-1436
-
-
-
9
-
-
1842478123
-
Current concepts in the pathogenesis of age-related macular degeneration
-
Zarbin MA. Current concepts in the pathogenesis of age-related macular degeneration. Arch Ophthalmol. 2004;122:598-614.
-
(2004)
Arch Ophthalmol
, vol.122
, pp. 598-614
-
-
Zarbin, M.A.1
-
11
-
-
0028879019
-
Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins
-
Snodderly DM. Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins. Am J Clin Nutr. 1995;62(suppl 6):1448S-161S.
-
(1995)
Am J Clin Nutr
, vol.62
, Issue.SUPPL. 6
-
-
Snodderly, D.M.1
-
12
-
-
0027930278
-
Evaluation of oxidative processes in human pigment epithelial cells associated with retinal outer segment phagocytosis
-
Miceli MV, Liles MR, Newsome DA. Evaluation of oxidative processes in human pigment epithelial cells associated with retinal outer segment phagocytosis. Exp Cell Res. 1994;214:242-249.
-
(1994)
Exp Cell Res
, vol.214
, pp. 242-249
-
-
Miceli, M.V.1
Liles, M.R.2
Newsome, D.A.3
-
13
-
-
0029562829
-
Lipofuscin of the retinal pigment epithelium: A review
-
Kennedy CJ, Rakoczy PE, Constable IJ. Lipofuscin of the retinal pigment epithelium: a review. Eye. 1995;9:763-771.
-
(1995)
Eye
, vol.9
, pp. 763-771
-
-
Kennedy, C.J.1
Rakoczy, P.E.2
Constable, I.J.3
-
15
-
-
0033795036
-
The role of oxidative stress in the pathogenesis of age-related macular degeneration
-
Beatty S, Koh H, Phil M, Henson D, Boulton M. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol. 2000;45:115-134.
-
(2000)
Surv Ophthalmol
, vol.45
, pp. 115-134
-
-
Beatty, S.1
Koh, H.2
Phil, M.3
Henson, D.4
Boulton, M.5
-
16
-
-
0020655183
-
Chemistry and metabolism of lipids in the vertebrate retina
-
Fliesler SJ, Anderson RE. Chemistry and metabolism of lipids in the vertebrate retina. Prog Lipid Res. 1983;22:79-131.
-
(1983)
Prog Lipid Res
, vol.22
, pp. 79-131
-
-
Fliesler, S.J.1
Anderson, R.E.2
-
18
-
-
0037375044
-
Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: A possible mechanism for RPE aging and age-related macular degeneration
-
Liang FQ, Godley BF. Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration. Exp Eye Res. 2003;76:397-403.
-
(2003)
Exp Eye Res
, vol.76
, pp. 397-403
-
-
Liang, F.Q.1
Godley, B.F.2
-
19
-
-
0025425556
-
Hemoprotein(s) mediate blue light damage in the retinal pigment epithelium
-
Pautler EL, Morita M, Beezley D. Hemoprotein(s) mediate blue light damage in the retinal pigment epithelium. Photochem Photobiol. 1990;51:599-605.
-
(1990)
Photochem Photobiol
, vol.51
, pp. 599-605
-
-
Pautler, E.L.1
Morita, M.2
Beezley, D.3
-
20
-
-
0036349652
-
Bcl-2 overexpression increases survival in human retinal pigment epithelial cells exposed to HO
-
Godley BF, Jin GF, Guo YS, Hurst JS. Bcl-2 overexpression increases survival in human retinal pigment epithelial cells exposed to HO. Exp Eye Res. 2002;74:663-669.
-
(2002)
Exp Eye Res
, vol.74
, pp. 663-669
-
-
Godley, B.F.1
Jin, G.F.2
Guo, Y.S.3
Hurst, J.S.4
-
21
-
-
0033034822
-
Oxidant-induced apoptosis in cultured human retinal pigment epithelial cells
-
Cai J, Wu M, Nelson KC, Sternberg P Jr, Jones DP. Oxidant-induced apoptosis in cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1999;40:959-966.
-
(1999)
Invest Ophthalmol Vis Sci
, vol.40
, pp. 959-966
-
-
Cai, J.1
Wu, M.2
Nelson, K.C.3
Sternberg Jr., P.4
Jones, D.P.5
-
22
-
-
0032504574
-
Mitochondrial control of apoptosis: The role of cytochrome c
-
Cai J, Yang J, Jones DP. Mitochondrial control of apoptosis: the role of cytochrome c. Biochim Biophys Acta. 1988;1366:139-149.
-
(1988)
Biochim Biophys Acta
, vol.1366
, pp. 139-149
-
-
Cai, J.1
Yang, J.2
Jones, D.P.3
-
24
-
-
2942565817
-
Mitochondria-derived reactive oxygen species mediate blue light-induced death of retinal pigment epithelial cells
-
King A, Gottlieb E, Brooks DG, Murphy MP, Dunaief JL. Mitochondria-derived reactive oxygen species mediate blue light-induced death of retinal pigment epithelial cells. Photochem Photobiol. 2004;79:470-475.
-
(2004)
Photochem Photobiol
, vol.79
, pp. 470-475
-
-
King, A.1
Gottlieb, E.2
Brooks, D.G.3
Murphy, M.P.4
Dunaief, J.L.5
-
25
-
-
0037705336
-
A2E-epoxides damage DNA in retinal pigment epithelial cells: Vitamin E and other anti-oxidants inhibit A2E-epoxide formation
-
Sparrow JR, Vollmer-Snarr HR, Zhou J, et al. A2E-epoxides damage DNA in retinal pigment epithelial cells: vitamin E and other anti-oxidants inhibit A2E-epoxide formation. J Biol Chem. 2003;278:18207-18213.
-
(2003)
J Biol Chem
, vol.278
, pp. 18207-18213
-
-
Sparrow, J.R.1
Vollmer-Snarr, H.R.2
Zhou, J.3
-
26
-
-
0036974163
-
Effects of hypoxia on retinal pigmented epithelium cells: Protection by antioxidants
-
Castillo M, Bellot JL, Garcia-Cabanes C, Miquel J, Orts A, Palmero M. Effects of hypoxia on retinal pigmented epithelium cells: protection by antioxidants. Ophthalmic Res. 2002;34:338-342.
-
(2002)
Ophthalmic Res
, vol.34
, pp. 338-342
-
-
Castillo, M.1
Bellot, J.L.2
Garcia-Cabanes, C.3
Miquel, J.4
Orts, A.5
Palmero, M.6
-
27
-
-
0032857578
-
Effect of dietary inducer dimethylfumarate on glutathione in cultured human retinal pigment epithelial cells
-
Nelson KC, Carlson JL, Newman ML, et al. Effect of dietary inducer dimethylfumarate on glutathione in cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1999;40:1927-1935.
-
(1999)
Invest Ophthalmol Vis Sci
, vol.40
, pp. 1927-1935
-
-
Nelson, K.C.1
Carlson, J.L.2
Newman, M.L.3
-
28
-
-
0036846489
-
Protection of retinal pigment epithelial cells from oxidative damage by oltipraz, a cancer chemopreventive agent
-
Nelson KC, Armstrong JS, Moriarty S, et al. Protection of retinal pigment epithelial cells from oxidative damage by oltipraz, a cancer chemopreventive agent. Invest Ophthalmol Vis Sci. 2002;43:3550-3554.
-
(2002)
Invest Ophthalmol Vis Sci
, vol.43
, pp. 3550-3554
-
-
Nelson, K.C.1
Armstrong, J.S.2
Moriarty, S.3
-
29
-
-
3142721782
-
Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage
-
Gao X, Talalay P. Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage. Proc Natl Acad Sci USA. 2004;101:10446-10451.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10446-10451
-
-
Gao, X.1
Talalay, P.2
-
31
-
-
0030915483
-
Mitochondrial decay in hepatocytes from old rats: Membrane potential declines, heterogeneity and oxidants increase
-
Hagen TM, Yowe DL, Bartholomew JC, et al. Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase. Proc Natl Acad Sci USA. 1997;94:3064-3069.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3064-3069
-
-
Hagen, T.M.1
Yowe, D.L.2
Bartholomew, J.C.3
-
32
-
-
0033042929
-
(R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate
-
Hagen TM, Ingersoll RT, Lykkesfeldt J, et al. (R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate. FASEB J. 1999;13:411-418.
-
(1999)
FASEB J
, vol.13
, pp. 411-418
-
-
Hagen, T.M.1
Ingersoll, R.T.2
Lykkesfeldt, J.3
-
33
-
-
0037133304
-
Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress
-
Hagen TM, Liu J, Lykkesfeldt J, et al. Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proc Natl Acad Sci USA. 2002;99:1870-1875.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 1870-1875
-
-
Hagen, T.M.1
Liu, J.2
Lykkesfeldt, J.3
-
34
-
-
0037133283
-
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid
-
Liu J, Head E, Gharib AM, et al. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid. Proc Natl Acad Sci USA. 2002;99:2356-236l.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
-
-
Liu, J.1
Head, E.2
Gharib, A.M.3
-
35
-
-
33747608757
-
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
-
In press
-
Suh JH, Shenvi SV, Dixon BM, et al. Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proc Natl Acad Sci USA. In press.
-
Proc Natl Acad Sci USA
-
-
Suh, J.H.1
Shenvi, S.V.2
Dixon, B.M.3
-
36
-
-
0033743950
-
(R)-alpha-lipoic acid reverses the age-associated increase in susceptibility of hepatocytes to tert-butylhydroperoxide both in vitro and in vivo
-
Hagen TM, Vinarsky V, Wehr CM, Ames BN. (R)-alpha-lipoic acid reverses the age-associated increase in susceptibility of hepatocytes to tert-butylhydroperoxide both in vitro and in vivo. Antioxid Redox Signal. 2000;2:473-483.
-
(2000)
Antioxid Redox Signal
, vol.2
, pp. 473-483
-
-
Hagen, T.M.1
Vinarsky, V.2
Wehr, C.M.3
Ames, B.N.4
-
37
-
-
0033991466
-
Oxidative damage and protection of the RPE
-
Cai J, Nelson KC, Wu M, Sternberg P Jr, Jones DP. Oxidative damage and protection of the RPE. Prog Retin Eye Res. 2000;19:205-221.
-
(2000)
Prog Retin Eye Res
, vol.19
, pp. 205-221
-
-
Cai, J.1
Nelson, K.C.2
Wu, M.3
Sternberg Jr., P.4
Jones, D.P.5
-
38
-
-
0020535984
-
On the relationship between Ca2+ efflux and membrane damage during t-butylhydroperoxide metabolism by liver mitochondria
-
Moore GA, Jewell SA, Bellomo G, Orrenius S. On the relationship between Ca2+ efflux and membrane damage during t-butylhydroperoxide metabolism by liver mitochondria. FEBS Lett. 1983;153:289-292.
-
(1983)
FEBS Lett
, vol.153
, pp. 289-292
-
-
Moore, G.A.1
Jewell, S.A.2
Bellomo, G.3
Orrenius, S.4
-
39
-
-
0023201205
-
Glutathione depleting agents and lipid peroxidation
-
Comporti M. Glutathione depleting agents and lipid peroxidation. Chem Phys Lipids. 1987;45:l43-l69.
-
(1987)
Chem Phys Lipids
, vol.45
-
-
Comporti, M.1
-
40
-
-
0026618868
-
Ion transport mechanisms in native human retinal pigment epithelium
-
Quinn RH, Miller SS. Ion transport mechanisms in native human retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1992;33:3513-3527.
-
(1992)
Invest Ophthalmol Vis Sci
, vol.33
, pp. 3513-3527
-
-
Quinn, R.H.1
Miller, S.S.2
-
41
-
-
0035164069
-
Adrenergic receptor activated ion transport in human fetal retinal pigment epithelium
-
Quinn RH, Quong JN, Miller SS. Adrenergic receptor activated ion transport in human fetal retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2001;42:255-264.
-
(2001)
Invest Ophthalmol Vis Sci
, vol.42
, pp. 255-264
-
-
Quinn, R.H.1
Quong, J.N.2
Miller, S.S.3
-
42
-
-
0026615870
-
Na-dependent pHi regulatory mechanisms in native human retinal pigment epithelium
-
Lin H, Kenyon E, Miller SS. Na-dependent pHi regulatory mechanisms in native human retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1992;33:3528-3538.
-
(1992)
Invest Ophthalmol Vis Sci
, vol.33
, pp. 3528-3538
-
-
Lin, H.1
Kenyon, E.2
Miller, S.S.3
-
43
-
-
0036847575
-
The P2Y receptor agonist INS37217 stimulates RPE fluid transport in vitro and retinal reattachment in rat
-
Maminishkis A, Jalickee S, Blaug SA, et al. The P2Y receptor agonist INS37217 stimulates RPE fluid transport in vitro and retinal reattachment in rat. Invest Ophthalmol Vis Sci. 2002;43:3555-3566.
-
(2002)
Invest Ophthalmol Vis Sci
, vol.43
, pp. 3555-3566
-
-
Maminishkis, A.1
Jalickee, S.2
Blaug, S.A.3
-
44
-
-
0000820462
-
Transport mechanisms in the retinal pigment epithelium
-
Marmor M, Wolfensberger T, eds. New York: Oxford University Press
-
Hughes B, Gallemore R, Miller S. Transport mechanisms in the retinal pigment epithelium. In: Marmor M, Wolfensberger T, eds. The Retinal Pigment Epithelium. New York: Oxford University Press; 1998:103-134.
-
(1998)
The Retinal Pigment Epithelium
, pp. 103-134
-
-
Hughes, B.1
Gallemore, R.2
Miller, S.3
-
45
-
-
0036533531
-
Mitochondrial and nonmitochondrial reduction of MTT: Interaction of MTT with TMRE, JC-1, and NAO mitochondrial fluorescent probes
-
Bernas T, Dobrucki J. Mitochondrial and nonmitochondrial reduction of MTT: interaction of MTT with TMRE, JC-1, and NAO mitochondrial fluorescent probes. Cytometry. 2002;47:236-242.
-
(2002)
Cytometry
, vol.47
, pp. 236-242
-
-
Bernas, T.1
Dobrucki, J.2
-
46
-
-
0028881848
-
Mitochondrial membrane potential monitored by JC-1 dye
-
Reers M, Smiley ST, Mottola-Hartshorn C, Chen A, Lin M, Chen LB. Mitochondrial membrane potential monitored by JC-1 dye. Methods Enzymol. 1995;260:406-417.
-
(1995)
Methods Enzymol
, vol.260
, pp. 406-417
-
-
Reers, M.1
Smiley, S.T.2
Mottola-Hartshorn, C.3
Chen, A.4
Lin, M.5
Chen, L.B.6
-
47
-
-
0030612749
-
JC-1, but not DiOCo or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: Implications for studies on mitochondrial functionality during apoptosis
-
Salvioli S, Ardizzoni A, Franceschi C, Cossarizza A. JC-1, but not DiOCo or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett. 1997;411:77-82.
-
(1997)
FEBS Lett
, vol.411
, pp. 77-82
-
-
Salvioli, S.1
Ardizzoni, A.2
Franceschi, C.3
Cossarizza, A.4
-
48
-
-
0032705639
-
A rapid method for the evaluation of compounds with mitochondria- protective properties
-
Nuydens R, Novalbos J, Dispersyn G, Weber C, Borgers M, Geerts H. A rapid method for the evaluation of compounds with mitochondria-protective properties. J. Neurosci Methods. 1999;92:153-159.
-
(1999)
J Neurosci Methods
, vol.92
, pp. 153-159
-
-
Nuydens, R.1
Novalbos, J.2
Dispersyn, G.3
Weber, C.4
Borgers, M.5
Geerts, H.6
-
49
-
-
0023079953
-
High-performance liquid chromatography of thiols and disulfides: Dinitrophenol derivatives
-
Fariss MW, Reed DJ. High-performance liquid chromatography of thiols and disulfides: dinitrophenol derivatives. Methods Enzymol. 1987;143:101-109.
-
(1987)
Methods Enzymol
, vol.143
, pp. 101-109
-
-
Fariss, M.W.1
Reed, D.J.2
-
51
-
-
0036240776
-
Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites
-
Liu J, Atamna H, Kuratsune H, Ames BN. Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites. Ann NY Acad Sci. 2002;959:133-l66.
-
(2002)
Ann NY Acad Sci
, vol.959
-
-
Liu, J.1
Atamna, H.2
Kuratsune, H.3
Ames, B.N.4
-
52
-
-
0036372619
-
Redox potential of GSH/GSSG couple: Assay and biological significance
-
Jones DP. Redox potential of GSH/GSSG couple: assay and biological significance. Methods Enzymol. 2002;348:93-112.
-
(2002)
Methods Enzymol
, vol.348
, pp. 93-112
-
-
Jones, D.P.1
-
53
-
-
0036205219
-
Involvement of oxidative mechanisms in blue-light-induced damage to A2E-laden RPE
-
Sparrow JR, Zhou J, Ben-Shabat S, Vollmer H, Itagaki Y, Nakanishi K. Involvement of oxidative mechanisms in blue-light-induced damage to A2E-laden RPE. Invest Ophthalmol Vis Sci. 2002;43:1222-1227.
-
(2002)
Invest Ophthalmol Vis Sci
, vol.43
, pp. 1222-1227
-
-
Sparrow, J.R.1
Zhou, J.2
Ben-Shabat, S.3
Vollmer, H.4
Itagaki, Y.5
Nakanishi, K.6
-
54
-
-
0029872876
-
ARPE-19, a human retinal pigment epithelial cell line with differentiated properties
-
Dunn KC, Aotaki-Keen AE, Putkey FR, Hjelmeland LM. ARPE-19, a human retinal pigment epithelial cell line with differentiated properties. Exp Eye Res. 1996;62:155-169.
-
(1996)
Exp Eye Res
, vol.62
, pp. 155-169
-
-
Dunn, K.C.1
Aotaki-Keen, A.E.2
Putkey, F.R.3
Hjelmeland, L.M.4
-
55
-
-
0030719486
-
Aerobic glycolysis by proliferating cells: Protection against oxidative stress at the expense of energy yield
-
Brand K. Aerobic glycolysis by proliferating cells: protection against oxidative stress at the expense of energy yield. J Bioenerg Biomembr. 1997;29:355-364.
-
(1997)
J Bioenerg Biomembr
, vol.29
, pp. 355-364
-
-
Brand, K.1
-
56
-
-
0033695541
-
Bioenergetics and mitochondrial transmembrane potential during differentiation of cultured osteoblasts
-
Komarova SV, Ataullakhanov FI, Globus RK. Bioenergetics and mitochondrial transmembrane potential during differentiation of cultured osteoblasts. Am J Physiol. 2000;279:C1220-C1229.
-
(2000)
Am J Physiol
, vol.279
-
-
Komarova, S.V.1
Ataullakhanov, F.I.2
Globus, R.K.3
-
57
-
-
21844441151
-
Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, Alzheimer's disease and Parkinson's disease
-
In press
-
Liu J, Ames B. Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, Alzheimer's disease and Parkinson's disease. Nutr Neurosci. In press.
-
Nutr Neurosci
-
-
Liu, J.1
Ames, B.2
-
58
-
-
0031682205
-
Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes: Reversal with (R)-alpha-lipoic acid supplementation
-
Lykkesfeldt J, Hagen TM, Vinarsky V, Ames BN. Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes: reversal with (R)-alpha-lipoic acid supplementation. FASEB J. 1998;12:1183-1189.
-
(1998)
FASEB J
, vol.12
, pp. 1183-1189
-
-
Lykkesfeldt, J.1
Hagen, T.M.2
Vinarsky, V.3
Ames, B.N.4
-
59
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K, et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science. 1997;275:1129-1132.
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
-
60
-
-
0043163463
-
Mitotropic compounds for the treatment of age-related macular degeneration: The metabolic approach and a pilot study
-
Feher J, Papale A, Mannino G, Gualdi L, Balacco Gabrieli C. Mitotropic compounds for the treatment of age-related macular degeneration: the metabolic approach and a pilot study. Ophthalmologica. 2003;217:351-357.
-
(2003)
Ophthalmologica
, vol.217
, pp. 351-357
-
-
Feher, J.1
Papale, A.2
Mannino, G.3
Gualdi, L.4
Balacco Gabrieli, C.5
-
61
-
-
0031761354
-
Determination of oxidized and reduced lipoic acid using high-performance liquid chromatography and coulometric detection
-
Sen CK, Roy S, Khanna S, Packer L. Determination of oxidized and reduced lipoic acid using high-performance liquid chromatography and coulometric detection. Methods Enzymol. 1999;299:239-246.
-
(1999)
Methods Enzymol
, vol.299
, pp. 239-246
-
-
Sen, C.K.1
Roy, S.2
Khanna, S.3
Packer, L.4
-
62
-
-
0036070514
-
Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid
-
Moini H, Packer L, Saris NE. Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid. Toxicol Appl Pharmacol. 2002;182:84-90.
-
(2002)
Toxicol Appl Pharmacol
, vol.182
, pp. 84-90
-
-
Moini, H.1
Packer, L.2
Saris, N.E.3
-
63
-
-
0000197851
-
Alpha-lipoic acid: A metabolic antioxidant and potential redox modulator of transcription
-
Packer L, Roy S, Sen CK. Alpha-lipoic acid: a metabolic antioxidant and potential redox modulator of transcription. Adv Pharmacol. 1997;38:79-101.
-
(1997)
Adv Pharmacol
, vol.38
, pp. 79-101
-
-
Packer, L.1
Roy, S.2
Sen, C.K.3
-
64
-
-
0029909010
-
Neuroprotection by the metabolic antioxidant alpha-lipoic acid
-
Packer L, Tritschler HJ, Wessel K. Neuroprotection by the metabolic antioxidant alpha-lipoic acid. Free Radic Biol Med. 1997;22:359-378.
-
(1997)
Free Radic Biol Med
, vol.22
, pp. 359-378
-
-
Packer, L.1
Tritschler, H.J.2
Wessel, K.3
-
65
-
-
0030768236
-
The pharmacology of the anti-oxidant lipoic acid
-
Biewenga GP, Haenen GR, Bast A. The pharmacology of the anti-oxidant lipoic acid. Gen Pharmacol. 1997;29:315-31.
-
(1997)
Gen Pharmacol
, vol.29
, pp. 315-331
-
-
Biewenga, G.P.1
Haenen, G.R.2
Bast, A.3
-
66
-
-
0029031443
-
Thioctic (lipoic) acid: A therapeutic metal-chelating antioxidant?
-
Ou P, Tritschler HJ, Wolff SP. Thioctic (lipoic) acid: a therapeutic metal-chelating antioxidant? Biochem Pharmacol. 1995;50:123-126.
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 123-126
-
-
Ou, P.1
Tritschler, H.J.2
Wolff, S.P.3
-
67
-
-
0037332176
-
Alpha lipoic acid changes iron uptake and storage in lens epithelial cells
-
Goralska M, Dackor R, Holley B, McGahan MC. Alpha lipoic acid changes iron uptake and storage in lens epithelial cells. Exp Eye Res. 2003;76:241-248.
-
(2003)
Exp Eye Res
, vol.76
, pp. 241-248
-
-
Goralska, M.1
Dackor, R.2
Holley, B.3
McGahan, M.C.4
-
68
-
-
0041560975
-
Maculas affected by age-related macular degeneration contain increased chelatable iron in the retinal pigment epithelium and Bruch's membrane
-
Hahn P, Milam AH, Dunaief JL. Maculas affected by age-related macular degeneration contain increased chelatable iron in the retinal pigment epithelium and Bruch's membrane. Arch Ophthalmol. 2003;121:1099-1105.
-
(2003)
Arch Ophthalmol
, vol.121
, pp. 1099-1105
-
-
Hahn, P.1
Milam, A.H.2
Dunaief, J.L.3
-
69
-
-
0035181945
-
Alpha-lipoic acid and alpha-lipoamide prevent oxidant-induced lysosomal rupture and apoptosis
-
Persson HL, Svensson AI, Brunk UT. Alpha-lipoic acid and alpha-lipoamide prevent oxidant-induced lysosomal rupture and apoptosis. Redox Rep. 2001;6:327-334.
-
(2001)
Redox Rep
, vol.6
, pp. 327-334
-
-
Persson, H.L.1
Svensson, A.I.2
Brunk, U.T.3
-
70
-
-
0037448064
-
Prevention of oxidant-induced cell death by lysosomotropic iron chelators
-
Persson HL, Yu Z, Tirosh O, Eaton JW, Brunk UT. Prevention of oxidant-induced cell death by lysosomotropic iron chelators. Free Radie Biol Med. 2003;34:1295-1305.
-
(2003)
Free Radie Biol Med
, vol.34
, pp. 1295-1305
-
-
Persson, H.L.1
Yu, Z.2
Tirosh, O.3
Eaton, J.W.4
Brunk, U.T.5
-
71
-
-
0027769391
-
Protection of retinal pigment epithelium from oxidative injury by glutathione and precursors
-
Sternberg P Jr, Davidson PC, Jones DP, Hagen TM, Reed RL, Drews-Botsch C. Protection of retinal pigment epithelium from oxidative injury by glutathione and precursors. Invest Ophthalmol Vis Sci. 1993;34:3661-3668.
-
(1993)
Invest Ophthalmol Vis Sci
, vol.34
, pp. 3661-3668
-
-
Sternberg Jr., P.1
Davidson, P.C.2
Jones, D.P.3
Hagen, T.M.4
Reed, R.L.5
Drews-Botsch, C.6
-
72
-
-
12144265572
-
Microsomal glutathione S-transferase 1 in the retinal pigment epithelium: Protection against oxidative stress and a potential role in aging
-
Maeda A, Crabb JW, Palczewski K. Microsomal glutathione S-transferase 1 in the retinal pigment epithelium: protection against oxidative stress and a potential role in aging. Biochemistry. 2005;44:480-489.
-
(2005)
Biochemistry
, vol.44
, pp. 480-489
-
-
Maeda, A.1
Crabb, J.W.2
Palczewski, K.3
-
73
-
-
0030696877
-
Lipoic acid increases de novo synthesis of cellular glutathione by improving cystine utilization
-
Han D, Handelman G, Marcocci L, et al. Lipoic acid increases de novo synthesis of cellular glutathione by improving cystine utilization. Biofactors. 1997;6:321-338.
-
(1997)
Biofactors
, vol.6
, pp. 321-338
-
-
Han, D.1
Handelman, G.2
Marcocci, L.3
-
74
-
-
0033655446
-
Regulation of glutathione synthesis
-
Lu SC. Regulation of glutathione synthesis. Curr Top Cell Regul. 2000;36:95-116.
-
(2000)
Curr Top Cell Regul
, vol.36
, pp. 95-116
-
-
Lu, S.C.1
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