메뉴 건너뛰기




Volumn 23, Issue 13, 2004, Pages 2620-2631

Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes

Author keywords

Intron; RNA export; Splicing; Transcription; TREX

Indexed keywords

DNA; PROTEIN HPR1P; PROTEIN SUB2P; PROTEIN TREX; PROTEIN YRA1P; RIBONUCLEASE; RNA; RNA BINDING PROTEIN; SMALL NUCLEOLAR RIBONUCLEOPROTEIN; UNCLASSIFIED DRUG;

EID: 3343003673     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600261     Document Type: Article
Times cited : (141)

References (51)
  • 1
    • 1542334001 scopus 로고    scopus 로고
    • Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3́ end processing
    • Ahn SH, Kim M, Buratowski S (2004) Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3́ end processing. Mol Cell 13: 67-76
    • (2004) Mol Cell , vol.13 , pp. 67-76
    • Ahn, S.H.1    Kim, M.2    Buratowski, S.3
  • 3
    • 0034329461 scopus 로고    scopus 로고
    • A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae
    • Chavez S, Beilharz T, Rondon AG, Erdjument-Bromage H, Tempst P, Svejstrup JQ, Lithgow T, Aguilera A (2000) A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae. EMBO J 19: 5824-5834
    • (2000) EMBO J , vol.19 , pp. 5824-5834
    • Chavez, S.1    Beilharz, T.2    Rondon, A.G.3    Erdjument-Bromage, H.4    Tempst, P.5    Svejstrup, J.Q.6    Lithgow, T.7    Aguilera, A.8
  • 4
    • 0033105008 scopus 로고    scopus 로고
    • Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II
    • Dye MJ, Proudfoot NJ (1999) Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II. Mol Cell 3: 371-378
    • (1999) Mol Cell , vol.3 , pp. 371-378
    • Dye, M.J.1    Proudfoot, N.J.2
  • 5
    • 0034932941 scopus 로고    scopus 로고
    • High-copy-number expression of Sub2p, a member of the RNA helicase superfamily, suppresses hpr1-mediated genomic instability
    • Fan HY, Merker RJ, Klein HL (2001) High-copy-number expression of Sub2p, a member of the RNA helicase superfamily, suppresses hpr1-mediated genomic instability. Mol Cell Biol 21: 5459-5470
    • (2001) Mol Cell Biol , vol.21 , pp. 5459-5470
    • Fan, H.Y.1    Merker, R.J.2    Klein, H.L.3
  • 7
    • 0742304306 scopus 로고    scopus 로고
    • Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1
    • GaIy V, Gadal O, Fromont-Racine M, Romano A, Jacquier A, Nehrbass U (2004) Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1. Cell 116: 63-73
    • (2004) Cell , vol.116 , pp. 63-73
    • GaIy, V.1    Gadal, O.2    Fromont-Racine, M.3    Romano, A.4    Jacquier, A.5    Nehrbass, U.6
  • 8
    • 0025994140 scopus 로고
    • Guide to yeast genetics and molecular biology
    • Guthrie C, Fink GR (1991) Guide to yeast genetics and molecular biology. Methods Enzymol 194: 389-398
    • (1991) Methods Enzymol , vol.194 , pp. 389-398
    • Guthrie, C.1    Fink, G.R.2
  • 11
    • 0141819093 scopus 로고    scopus 로고
    • Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination
    • Huertas P, Aguilera A (2003) Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination. Mol Cell 12: 711-721
    • (2003) Mol Cell , vol.12 , pp. 711-721
    • Huertas, P.1    Aguilera, A.2
  • 12
    • 0036645687 scopus 로고    scopus 로고
    • The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability
    • Jimeno S, Rondon AG, Luna R, Aguilera A (2002) The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability. EMBO J 21: 3526-3535
    • (2002) EMBO J , vol.21 , pp. 3526-3535
    • Jimeno, S.1    Rondon, A.G.2    Luna, R.3    Aguilera, A.4
  • 13
    • 0036242097 scopus 로고    scopus 로고
    • Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis
    • Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ (2002) Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. RNA 8: 426-439
    • (2002) RNA , vol.8 , pp. 426-439
    • Jurica, M.S.1    Licklider, L.J.2    Gygi, S.R.3    Grigorieff, N.4    Moore, M.J.5
  • 14
    • 0037076221 scopus 로고    scopus 로고
    • HEL/UAP56 binds cotranscriptionally to the Balbiani ring pre-mRNA in an intron-independent manner and accompanies the BR mRNP to the nuclear pore
    • Kiesler E, Miralles F, Visa N (2002) HEL/UAP56 binds cotranscriptionally to the Balbiani ring pre-mRNA in an intron-independent manner and accompanies the BR mRNP to the nuclear pore. Curr Biol 12: 859-862
    • (2002) Curr Biol , vol.12 , pp. 859-862
    • Kiesler, E.1    Miralles, F.2    Visa, N.3
  • 15
    • 1542290655 scopus 로고    scopus 로고
    • Transitions in RNA polymerase II elongation complexes at the 3′ ends of genes
    • Kim M, Ahn SH, Krogan NJ, Greenblatt JF, Buratowski S (2004) Transitions in RNA polymerase II elongation complexes at the 3′ ends of genes. EMBO J 23: 354-364
    • (2004) EMBO J , vol.23 , pp. 354-364
    • Kim, M.1    Ahn, S.H.2    Krogan, N.J.3    Greenblatt, J.F.4    Buratowski, S.5
  • 16
    • 0035177309 scopus 로고    scopus 로고
    • Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for sub2, an essential spliceosomal ATPase
    • Kistler AL, Guthrie C (2001) Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for sub2, an essential spliceosomal ATPase. Genes Dev 15: 42-49
    • (2001) Genes Dev , vol.15 , pp. 42-49
    • Kistler, A.L.1    Guthrie, C.2
  • 17
    • 0034307008 scopus 로고    scopus 로고
    • Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription
    • Komarnitsky P, Cho EJ, Buratowski S (2000) Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. Genes Dev 14: 2452-2460
    • (2000) Genes Dev , vol.14 , pp. 2452-2460
    • Komarnitsky, P.1    Cho, E.J.2    Buratowski, S.3
  • 18
    • 0041630999 scopus 로고    scopus 로고
    • Cotranscriptional recruitment of the U1 snRNP to intron-containing genes in yeast
    • Kotovic KM, Lockshon D, Boric L, Neugebauer KM (2003) Cotranscriptional recruitment of the U1 snRNP to intron-containing genes in yeast. Mol Cell Biol 23: 5768-5779
    • (2003) Mol Cell Biol , vol.23 , pp. 5768-5779
    • Kotovic, K.M.1    Lockshon, D.2    Boric, L.3    Neugebauer, K.M.4
  • 19
    • 0035002059 scopus 로고    scopus 로고
    • Interruption of coding sequences by heterologous introns can enhance the functional expression of recombinant genes
    • Lacy-Hulbert A, Thomas R, Li XP, Lilley CE, Coffin RS, Roes J (2001) Interruption of coding sequences by heterologous introns can enhance the functional expression of recombinant genes. Gene Therapy 8: 649-653
    • (2001) Gene Therapy , vol.8 , pp. 649-653
    • Lacy-Hulbert, A.1    Thomas, R.2    Li, X.P.3    Lilley, C.E.4    Coffin, R.S.5    Roes, J.6
  • 20
    • 0034672093 scopus 로고    scopus 로고
    • The spliceo-some deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions
    • Le Hir H, Izaurralde E, Maquat LE, Moore MJ (2000) The spliceo-some deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions. EMBO J 19: 6860-6869
    • (2000) EMBO J , vol.19 , pp. 6860-6869
    • Le Hir, H.1    Izaurralde, E.2    Maquat, L.E.3    Moore, M.J.4
  • 21
    • 0024973850 scopus 로고
    • Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm
    • Legrain P, Rosbash M (1989) Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm. Cell 57: 573-583
    • (1989) Cell , vol.57 , pp. 573-583
    • Legrain, P.1    Rosbash, M.2
  • 22
    • 0035878119 scopus 로고    scopus 로고
    • Messenger RNAs are recruited for nuclear export during transcription
    • Lei EP, Krebber H, Silver PA (2001) Messenger RNAs are recruited for nuclear export during transcription. Genes Dev 15: 1771-1782
    • (2001) Genes Dev , vol.15 , pp. 1771-1782
    • Lei, E.P.1    Krebber, H.2    Silver, P.A.3
  • 23
    • 0036829415 scopus 로고    scopus 로고
    • Intron status and 3′-end formation control Cotranscriptional export of mRNA
    • Lei EP, Silver PA (2002) Intron status and 3′-end formation control Cotranscriptional export of mRNA. Genes Dev 16: 2761-2766
    • (2002) Genes Dev , vol.16 , pp. 2761-2766
    • Lei, E.P.1    Silver, P.A.2
  • 24
    • 0036889142 scopus 로고    scopus 로고
    • Interactions between mRNA export commitment, 3′-end quality control, and nuclear degradation
    • Libri D, Dower K, Boulay J, Thomsen R, Rosbash M, Jensen TH (2002) Interactions between mRNA export commitment, 3′-end quality control, and nuclear degradation. Mol Cell Biol 22: 8254-8266
    • (2002) Mol Cell Biol , vol.22 , pp. 8254-8266
    • Libri, D.1    Dower, K.2    Boulay, J.3    Thomsen, R.4    Rosbash, M.5    Jensen, T.H.6
  • 25
    • 0035180388 scopus 로고    scopus 로고
    • Multiple roles for the yeast SUB2/yUAP56 gene in splicing
    • Libri D, Graziani N, Saguez C, Boulay J (2001) Multiple roles for the yeast SUB2/yUAP56 gene in splicing. Genes Dev 15: 36-41
    • (2001) Genes Dev , vol.15 , pp. 36-41
    • Libri, D.1    Graziani, N.2    Saguez, C.3    Boulay, J.4
  • 27
    • 0035846138 scopus 로고    scopus 로고
    • Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly
    • Luo ML, Zhou Z, Magni K, Christoforides C, Rappsilber J, Mann M, Reed R (2001) Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly. Nature 413: 644-647
    • (2001) Nature , vol.413 , pp. 644-647
    • Luo, M.L.1    Zhou, Z.2    Magni, K.3    Christoforides, C.4    Rappsilber, J.5    Mann, M.6    Reed, R.7
  • 29
    • 0024988383 scopus 로고
    • In vitro polyadenylation is stimulated by the presence of an upstream intron
    • Niwa M, Rose SD, Berget SM (1990) In vitro polyadenylation is stimulated by the presence of an upstream intron. Genes Dev 4: 1552-1559
    • (1990) Genes Dev , vol.4 , pp. 1552-1559
    • Niwa, M.1    Rose, S.D.2    Berget, S.M.3
  • 31
    • 0036674269 scopus 로고    scopus 로고
    • Large-scale proteomic analysis of the human spliceosome
    • Rappsilber J, Ryder U, Lamond AI, Mann M (2002) Large-scale proteomic analysis of the human spliceosome. Genome Res 12: 1231-1245
    • (2002) Genome Res , vol.12 , pp. 1231-1245
    • Rappsilber, J.1    Ryder, U.2    Lamond, A.I.3    Mann, M.4
  • 32
    • 0036826885 scopus 로고    scopus 로고
    • 5′ exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly
    • Reichert V, Le Hir H, Jurica MS, Moore M (2002) 5′ exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly. Genes Dev 16: 2778-2791
    • (2002) Genes Dev , vol.16 , pp. 2778-2791
    • Reichert, V.1    Le Hir, H.2    Jurica, M.S.3    Moore, M.4
  • 34
    • 0033990048 scopus 로고    scopus 로고
    • Primer3 on the WWW for general users and for biologist programmers
    • Rozen S, Skaletsky H (2000) Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 132: 365-386
    • (2000) Methods Mol Biol , vol.132 , pp. 365-386
    • Rozen, S.1    Skaletsky, H.2
  • 35
    • 0343729923 scopus 로고    scopus 로고
    • A dual role for BBP/ScSF1 in nuclear pre-mRNA retention and splicing
    • Rutz B, Seraphin B (2000) A dual role for BBP/ScSF1 in nuclear pre-mRNA retention and splicing. EMBO J 19: 1873-1886
    • (2000) EMBO J , vol.19 , pp. 1873-1886
    • Rutz, B.1    Seraphin, B.2
  • 36
    • 0032964808 scopus 로고    scopus 로고
    • The Saccharomyces cereuisiae hyperrecombination mutant hpr1Delta is synthetically lethal with two conditional alleles of the acetyl coenzyme A carboxylase gene and causes a defect in nuclear export of polyadenylated RNA
    • Schneller R, Guerra CE, Lampl M, Gogg G, Kohlwein SD, Klein HL (1999) The Saccharomyces cereuisiae hyperrecombination mutant hpr1Delta is synthetically lethal with two conditional alleles of the acetyl coenzyme A carboxylase gene and causes a defect in nuclear export of polyadenylated RNA. Mol Cell Biol 19: 3415-3422
    • (1999) Mol Cell Biol , vol.19 , pp. 3415-3422
    • Schneller, R.1    Guerra, C.E.2    Lampl, M.3    Gogg, G.4    Kohlwein, S.D.5    Klein, H.L.6
  • 38
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski RS, Hieter P (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 39
    • 0043171067 scopus 로고    scopus 로고
    • Chromatin immunoprecipitation: A tool for studying histone acetylation and transcription factor binding
    • Spencer VA, Sun JM, Li L, Davie JR (2003) Chromatin immunoprecipitation: a tool for studying histone acetylation and transcription factor binding. Methods 31: 67-75
    • (2003) Methods , vol.31 , pp. 67-75
    • Spencer, V.A.1    Sun, J.M.2    Li, L.3    Davie, J.R.4
  • 40
    • 0034698683 scopus 로고    scopus 로고
    • Binding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export
    • Strasser K, Bassler J, Hurt E (2000) Binding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export. J Cell Biol 150: 695-706
    • (2000) J Cell Biol , vol.150 , pp. 695-706
    • Strasser, K.1    Bassler, J.2    Hurt, E.3
  • 41
    • 0035846109 scopus 로고    scopus 로고
    • Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p
    • Strasser K, Hurt E (2001) Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p. Nature 413: 648-652
    • (2001) Nature , vol.413 , pp. 648-652
    • Strasser, K.1    Hurt, E.2
  • 42
    • 0141469976 scopus 로고    scopus 로고
    • Yra1p, a conserved nuclear RNA binding protein, interacts directly with Mex67 and is required for mRNA export
    • Sträßer K, Hurt E (2000) Yra1p, a conserved nuclear RNA binding protein, interacts directly with Mex67 and is required for mRNA export. EMBO J 19: 410-420
    • (2000) EMBO J , vol.19 , pp. 410-420
    • Sträßer, K.1    Hurt, E.2
  • 44
    • 0028070676 scopus 로고
    • Proteins binding to 5́ untranslated region sites: A general mechanism for translational regulation of mRNAs in human and yeast cells
    • Stripecke R, Oliveira CC, McCarthy JE, Hentze MW (1994) Proteins binding to 5́ untranslated region sites: a general mechanism for translational regulation of mRNAs in human and yeast cells. Mol Cell Biol 14: 5898-5909
    • (1994) Mol Cell Biol , vol.14 , pp. 5898-5909
    • Stripecke, R.1    Oliveira, C.C.2    McCarthy, J.E.3    Hentze, M.W.4
  • 45
    • 0033625090 scopus 로고    scopus 로고
    • REF, an evolutionarily conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA export
    • Stutz F, Bachi A, Doerks T, Braun I, Seraphin B, Wilm M, Bork P, Izaurralde E (2000) REF, an evolutionarily conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA export. RNA 6: 638-650
    • (2000) RNA , vol.6 , pp. 638-650
    • Stutz, F.1    Bachi, A.2    Doerks, T.3    Braun, I.4    Seraphin, B.5    Wilm, M.6    Bork, P.7    Izaurralde, E.8
  • 46
    • 0024328155 scopus 로고
    • Inhibition of in vivo and in vitro transcription by monoclonal antibodies prepared against wheat germ RNA polymerase II that react with the heptapeptide repeat of eukaryotic RNA polymerase II
    • Thompson NE, Steinberg TH, Aronson DB, Burgess RR (1989) Inhibition of in vivo and in vitro transcription by monoclonal antibodies prepared against wheat germ RNA polymerase II that react with the heptapeptide repeat of eukaryotic RNA polymerase II. J Biol Chem 264: 11511-11520
    • (1989) J Biol Chem , vol.264 , pp. 11511-11520
    • Thompson, N.E.1    Steinberg, T.H.2    Aronson, D.B.3    Burgess, R.R.4
  • 47
    • 0141864354 scopus 로고    scopus 로고
    • Rds3p is required for stable U2 snRNP recruitment to the splicing apparatus
    • Wang Q, Rymond BC (2003) Rds3p is required for stable U2 snRNP recruitment to the splicing apparatus. Mol Cell Biol 23: 7339-7349
    • (2003) Mol Cell Biol , vol.23 , pp. 7339-7349
    • Wang, Q.1    Rymond, B.C.2
  • 48
    • 0034971040 scopus 로고    scopus 로고
    • The yeast hnRNP-Like proteins Yra1p and Yra2p participate in mRNA export through interaction with Mex67p
    • Zenklusen D, Vinciguerra P, Strahm Y, Stutz F (2001) The yeast hnRNP-Like proteins Yra1p and Yra2p participate in mRNA export through interaction with Mex67p. Mol Cell Biol 21: 4219-4232
    • (2001) Mol Cell Biol , vol.21 , pp. 4219-4232
    • Zenklusen, D.1    Vinciguerra, P.2    Strahm, Y.3    Stutz, F.4
  • 49
    • 0036889334 scopus 로고    scopus 로고
    • Stable mRNP formation and export require cotranscriptional recruitment of the mRNA export factors Yra1p and Sub2p by Hpr1p
    • Zenklusen D, Vinciguerra P, Wyss JC, Stutz F (2002) Stable mRNP formation and export require cotranscriptional recruitment of the mRNA export factors Yra1p and Sub2p by Hpr1p. Mol Cell Biol 22: 8241-8253
    • (2002) Mol Cell Biol , vol.22 , pp. 8241-8253
    • Zenklusen, D.1    Vinciguerra, P.2    Wyss, J.C.3    Stutz, F.4
  • 50
    • 0035187881 scopus 로고    scopus 로고
    • Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56
    • Zhang M, Green MR (2001) Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56. Genes Dev 15: 30-35
    • (2001) Genes Dev , vol.15 , pp. 30-35
    • Zhang, M.1    Green, M.R.2
  • 51
    • 0034699472 scopus 로고    scopus 로고
    • The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans
    • Zhou Z, Luo MJ, Straesser K, Katahira J, Hurt E, Reed R (2000) The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans. Nature 407: 401-405
    • (2000) Nature , vol.407 , pp. 401-405
    • Zhou, Z.1    Luo, M.J.2    Straesser, K.3    Katahira, J.4    Hurt, E.5    Reed, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.