Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of huntington's disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 17, 2000, Pages 9701-9705

  Carmichael, Jenny ^a   Chatellier, Jean ^b,d   Woolfson, Adrian ^c   Milstein, César ^c   Fersht, Alan R ^b   Rubinsztein, David C ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^d Avidis SA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CHAPERONE; FUNGAL PROTEIN; HEAT SHOCK PROTEIN; HUNTINGTIN; MUTANT PROTEIN; POLYGLUTAMINE;

ANIMAL CELL; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BACTERIUM; CELL AGGREGATION; CELL DEATH; CELL INCLUSION; CONTROLLED STUDY; EXON; HUNTINGTON CHOREA; MAMMAL CELL; MODEL; NONHUMAN; NUCLEOTIDE REPEAT; PATHOGENESIS; PRIORITY JOURNAL; RAT; RNA TRANSLATION; YEAST;

ANIMALIA; BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 0034662915     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.170280697     Document Type: Article

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