Aminoglycoside-hybrid ligands targeting the ribosomal decoding site

ChemBioChem

Volumn 6, Issue 1, 2005, Pages 58-65

  Vourloumis, Dionisios ^a   Winters, Geoffrey C ^a   Simonsen, Klaus B ^a   Takahashi, Masayuki ^a   Ayida, Benjamin K ^a   Shandrick, Sarah ^a   Zhao, Qiang ^a   Han, Qing ^a   Hermann, Thomas ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Aminoglycosides; Antibiotics; Drug design; Medicinal chemistry; RNA recognition

Indexed keywords

2,5 DIDEOXYSTREPTAMINE; 5 DEOXYNEAMINE DERIVATIVE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; BACTERIAL RNA; FRAMYCETIN; HYGROMYCIN B; LIGAND; NEAMINE; NEOMYCIN; PAROMOMYCIN; RIBOSOME RNA; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DRUG BINDING SITE; DRUG POTENCY; ESCHERICHIA COLI; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RIBOSOME; RNA BINDING; STAPHYLOCOCCUS AUREUS; STRUCTURE ANALYSIS; TRANSLATION REGULATION;

AMINOGLYCOSIDES; BASE SEQUENCE; BINDING SITES; LIGANDS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, SECONDARY; RNA, RIBOSOMAL;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 12344308343     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200400197     Document Type: Article

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