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Volumn 6, Issue 4, 2002, Pages 447-452

Protein flexibility and drug design: How to hit a moving target

Author keywords

[No Author keywords available]

Indexed keywords

DRUG; LIGAND; PROTEIN;

EID: 0036680063     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(02)00341-1     Document Type: Review
Times cited : (288)

References (44)
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    • Designing non-peptide peptidomimetics in the 21st century: Inhibitors targeting conformational ensembles
    • (2002) J Med Chem , vol.45 , pp. 541-558
    • Bursavich, M.G.1    Rich, D.H.2
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    • A method for including protein flexibility in protein-ligand docking: Improving tools for database mining and virtual screening
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    • Broughton, H.B.1
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    • Binding mode prediction for a flexible ligand in a flexible pocket using multi-conformation simulated annealing pseudo crystallographic refinement
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    • Prediction of potential toxicity and side effect protein targets of a small molecule by ligand-protein inverse docking approach
    • (2001) J Mol Graph Model , vol.20 , pp. 199-218
    • Chen, Y.Z.1    Ung, C.Y.2
  • 42
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    • Ligand-protein inverse docking and its potential use in the computer search of protein targets of a small molecule
    • (2001) Proteins , vol.43 , pp. 217-226
    • Chen, Y.Z.1    Zhi, D.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.