Ligand-induced conformational changes: Improved predictions of ligand binding conformations and affinities

Biophysical Journal

Volumn 84, Issue 4, 2003, Pages 2273-2281

  Frimurer, Thomas M ^a   Peters, Günther H ^b   Iversen, Lars F ^c   Andersen, Henrik S ^c   Møller, Niels Peter H ^c   Olsen, Ole H ^c  

^a Rønnegade 2 ^*  (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^c NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ENZYME INHIBITOR; LIGAND; PROTEIN; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CALCULATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME INHIBITION; LIGAND BINDING; MODEL; PKA; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

EID: 0037379786     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(03)75033-4     Document Type: Article

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